Tumo pituitary

ʻO ka tumo pituitary kahi ulu ulu ʻole o ka pituitary gland. ʻO ka pituitary kahi gland liʻiliʻi ma ke kumu o ka lolo. Hoʻoponopono ia i ke kaulike o ke kino o nā hormones he nui.

ʻO ka hapa nui o nā pituitary tumors he noncancerous (benign). Aia a 20% o ka poʻe i loaʻa i nā tumors pituitary. ʻO ka hapa nui o kēia mau tumors ʻaʻole kumu o nā ʻōuli a ʻike ʻole ʻia i ke ola o ke kanaka.

ʻO ka pituitary kahi ʻāpana o ka ʻōnaehana endocrine. Kōkua ka pituitary i ka hoʻokuʻu ʻia ʻana o nā homone mai nā gland endocrine ʻē aʻe, e like me ka thyroid, nā gland sex (testes a ovaries), a me nā adrenal glands. Hoʻokuʻu pū ka pituitary i nā hormoni e hoʻopili pololei i nā kino o ke kino, e like me nā iwi a me nā momona o ka waiū. Aia nā hormones pituitary i:

• Adrenocorticotropic hormone (ACTH)
• Hone ulu (GH)
• ʻO Prolactin
• ʻO ka hōmona stimulus thyroid (TSH)
• Luteinizing hormone (LH) a me follicle-stimulate hormone (FSH)

Ke ulu nei kahi pituitary tumor, e hōʻino ʻia paha nā cell e hoʻokuʻu ana i ka hormone maʻamau o ka pituitary. ʻO kēia ka hopena i ka pituitary gland ʻaʻole e hana pono i kāna mau hormones. Kapa ʻia kēia ʻano hypopituitarism.

ʻAʻole ʻike ʻia nā kumu o nā pituitary tumors. Hoʻokumu ʻia kekahi mau tumors e nā maʻi hoʻoilina e like me nā neoplasia endocrine I (MEN I).

Hiki ke hoʻopili ʻia ka pituitary gland e nā tumors lolo ʻē aʻe e hoʻomohala i ka ʻāpana like o ka lolo (kumu iwi poʻo), e hopena ai i nā ʻōuli like.

Hana kekahi mau pituitary tumors i ka nui o hoʻokahi a ʻoi paha nā hormona. A ʻo kahi hopena, hiki i nā ʻōuli o hoʻokahi a ʻoi paha o nā kūlana aʻe ke kū aʻe.

• ʻO Hyperthyroidism (hana ka nui o kāna mau homone i ka thyroid gland; he ʻano maʻamau loa kēia o nā pituitary tumors)
• ʻO Cushing Syndrome (ʻoi aku ke kiʻekiʻe o ke kino ma mua o ka pae maʻamau o ka hormone cortisol)
• Gigantism (ka ulu ulu ʻole ma muli o ke kiʻekiʻe ma mua o ka pae maʻamau o ka hormone ulu i ka wā kamaliʻi) a i ʻole acromegaly (ʻoi aku ma mua o ka pae maʻamau o ka hormone ulu i nā mākua)
• Ka hoʻokuʻu ʻana o ka nipple a me nā wā maʻamau a maʻa mau ʻole i nā wahine
• Hoʻoemi i ka hana moekolohe ma nā kāne

ʻO nā ʻōuli i hoʻokumu ʻia e ke kaomi mai kahi tumo pituitary ʻoi aku paha e komo pū:

• Nā loli i ka hihiʻo e like me ka hihiʻo lua, nalo ʻana o ke kahua ʻike (nalowale o ka ʻike ākea), nā lihilihi maka a i ʻole nā ​​hoʻololi i ka hihi kala.
• ʻEha poʻo.
• Ka nele o ka ikehu.
• Nalu kahe o ka wai mōakāka, paʻakai.
• ʻO Nusea a me ka luaʻi.
• Nā pilikia me ke ʻano o ka pilau.
• I nā hihia maʻamau, kū koke kēia mau ʻōuli a hiki ke koʻikoʻi (pituitary apoplexy).

E hana kāu mea mālama ola i kahi hoʻokolokolo kino. E hoʻomaopopo ka mea hāʻawi i nā pilikia me ka ʻike pālua a me ke kahua ʻike, e like me ka nalo ʻana o ka ʻaoʻao (peripheral) ʻike a i ʻole ka hiki ke ʻike i kekahi mau wahi.

E nānā ka hoʻokolohua no nā hōʻailona o ka nui o ka cortisol (Cushing syndrome), ka nui o ka hormone ulu (acromegaly), a me ka nui o ka prolactin (prolactinoma).

Hiki ke kauoha ʻia nā hoʻāʻo e nānā i ka hana endocrine, me:

• Nā pae Cortisol - hōʻike dexamethasone suppression test, mimi Cortisol test, salivary Cortisol test
• Pae FSH
• ʻO ka pae ulu Insulin-1 (IGF-1) pae
• LHlevel
• Pae Prolactin
• Nā pae testosterone / estradiol
• Nā pae hormone thyroid - hoʻāʻo T4 manuahi, hoʻāʻo TSH

ʻO nā hoʻāʻo e kōkua i ka hōʻoia ʻana i ka hōʻailona me kēia mau mea:

• Nā kahua hiʻona
• MRI o ke poʻo

ʻO ke ʻoki kino e kāpae pinepine ai i ka tumo, keu hoʻi inā ke kaomi nei ka tumo i nā ʻalolo e kaohi ana i ka ʻike (optic nerves).

ʻO ka hapanui o ka manawa, hiki ke wehe ʻia i nā tumā pituitary ma o ka ihu a me nā sinus. Inā ʻaʻole hiki ke hemo i ka tumo i kēia ala, hemo ia ma ka iwi poʻo.

Hiki ke hoʻohana ʻia ka radiation radiation e hoʻoliʻiliʻi i ka tumo i ka poʻe hiki ʻole ke ʻoki kino. Hiki ke hoʻohana ʻia inā hoʻi ka tumo ma hope o ke kahakaha ʻana.

I kekahi mau hihia, kauoha ʻia nā lāʻau e hoʻoliʻiliʻi i kekahi ʻano tumors.

Hiki i kēia mau kumuwaiwai ke hāʻawi i ka ʻikepili hou aʻe e pili ana i nā pituitary tumors:

• Ke Keʻena ʻInikena Mīkini - www.cancer.gov/types/pituitary
• ʻAhahui Pūnaewele Pituitary - pituitary.org
• ʻO ka Pituitary Society - www.pituitarysociety.org

Inā hiki ke hoʻoneʻe ʻia i ka tumo, kūpono ka nānā i ka maikaʻi, kaukaʻi ʻia inā wehe ʻia ka tumo holoʻokoʻa.

ʻO ka pilikia koʻikoʻi ka makapō. Hiki i kēia ke hana inā hōʻino nui ʻia ke aʻalolo optic.

ʻO ka tumo a i ʻole kona hemo ʻana paha ke kumu o ke kaulike ʻole o ke ola a pau. Pono paha e hoʻololi i nā homona i hoʻopilikia ʻia, a pono ʻoe e ʻai i ka lāʻau no ke koena o kou ola.

Hiki i nā tumors a me ke kahakaha ke hōʻino i ka pituitary o hope (ka ʻaoʻao hope o ka momona). Hiki i kēia ke alakaʻi i ka maʻi diabetes insipidus, kahi ʻano me nā ʻōuli o ka urination pinepine a me ka make wai loa.

Kāhea i kāu mea hāʻawi inā hoʻomohala ʻoe i nā hōʻailona o ka tumo pituitary.

Tumor - pituitary; Pituitary adenoma

• Nānā Endocrine
• Kelepona pituitary

ʻO Dorsey JF, Salinas RD, Dang M, et al. Ka maʻi ʻaʻai o ka ʻōnaehana waena. I: Niederhuber JE, Armitage JO, Kastan MB, Doroshow JH, Tepper JE, eds. ʻO Oncology Clinical ʻo Abboff. ʻElua huaʻōlelo Piladelapia, PA: Elsevier; 2020: chap 63.

Melmed S, Kleinberg D. Pituitary masses a me nā tumors. I: Melmed S, Polonsky KS, Larsen PR, Kronenberg HM, eds. ʻO Williams Textbook of Endocrinology. 13th ed. Piladelapia, PA: Elsevier; 2016: chap 9.