Ka nele o ka antithrombin III nele

ʻO ka nele o ka antithrombin III hemahema kahi maʻi genetical e kumu i ke kōkuʻu o ke koko ma mua o ka maʻamau.

ʻO Antithrombin III kahi protein i loko o ke koko e ālai ana i nā clots koko ʻole mai ka hana ʻana. Kōkua ia i ke kino e mālama i ke kaulike olakino ma waena o ke kahe ʻana o ke kaho a me ka ʻōpala ʻana. ʻO ka hemahema antithrombin III hemahema kahi maʻi hoʻoilina. Hana ʻia ia ke loaʻa i ke kanaka kekahi kope pono ʻole o ka gen antithrombin III mai kahi makua me ka maʻi.

Ke alakaʻi nei ka gen abnormal i kahi pae haʻahaʻa o ka protein antithrombin III. Hiki i kēia pae haʻahaʻa o antithrombin III ke kumu i ke kahe o ke koko (thrombi) i hiki ke pale i ke kahe o ke koko a hōʻino i nā lālā.

ʻO ka poʻe me kēia ʻano e loaʻa pinepine lākou i ke koko koko i ka wā ʻōpio. Loaʻa paha iā lākou kekahi mau ʻohana i loaʻa i kahi pilikia pili koko.

E loaʻa pinepine nā kānaka i nā ʻōuli o ke kōkuʻu koko. ʻO ke kuʻi koko i nā lima a me nā wāwae ke kumu o ka pehu, ʻulaʻula, a me ka ʻeha. Ke haki ke koko koko mai kahi i hana a hele i kekahi ʻāpana o ke kino, ua kapa ʻia he thromboembolism. Pili nā ʻōuli i kahi e hele ai ke koko. ʻO kahi maʻamau ka lung, kahi e hiki ai i ka hāpau ke kumu i ka puʻu, ka pōkole o ka hanu, ʻeha ke lawe nei i nā hanu hohonu, ʻeha o ka umauma, a me ka make pū kekahi. Hiki ke hōʻeha i nā kahe koko e holo i ka lolo.

E hōʻike paha kahi hōʻike kino:

• ʻO ka wāwae a pehu paha
• Kani ka hanu emi i nā akemāmā
• Kahi wikiwiki wikiwiki

Hiki i ke kauka olakino ke kauoha i kahi hoʻokolohua koko e nānā inā he pae haʻahaʻa kāu o ka antithrombin III.

Mālama ʻia kahi ʻōpala o ke koko me nā lāʻau lapaʻau hōʻemi koko (i kapa ʻia hoʻi nā anticoagulants). Pehea ka lōʻihi e pono ai ʻoe e lawe i kēia mau lāʻau e pili ana i ka nui o ke koko a me nā kumu ʻē aʻe. Kūkākūkā i kēia me kāu mea hāʻawi.

Hiki i kēia mau kumuwaiwai ke hāʻawi i ka ʻike hou aku e pili ana i ka hemahema antithrombin III hemahema:

• National Organization for Rare Disorder - rarediseases.org/rare-diseases/antithrombin-deficiency
• NLM Genetics Home Reference - ghr.nlm.nih.gov/condition/hereditary-antithrombin-deficiency

Loaʻa ka hopena maikaʻi ka hapa nui o ka poʻe inā noho lākou ma nā lāʻau anticoagulant.

Hiki i ke kahe koko ke hana i ka make. Hoʻoweliweli loa ke kuʻi koko i nā akemāmā.

E ʻike i kāu mea hāʻawi inā loaʻa iā ʻoe nā ʻōuli o kēia ʻano.

I ka manawa e ʻike ʻia kekahi kanaka me ka hemahema antithrombin III, pono e hoʻopaʻa ʻia nā lālā ʻohana pili āpau no kēia maʻi. Hiki i nā lāʻau hoʻohaʻahaʻa koko ke pale i nā kaola koko mai ka hana ʻana a pale i nā pilikia mai ka hoʻopili ʻana.

Ka nele - antithrombin III - hānau hānau; Ka hemahema Antithrombin III - hānau hānau

• ʻŌpū koko Venous

ʻO Anderson JA, Hogg KE, Weitz JI. Nā mokuʻāina ʻo Hypercoagulable. I: Hoffman R, Benz EJ, Silberstein LE, et al, eds. Hematology: Nā Kumumanaʻo a me ka Hoʻomeheu. ʻEpekema 7 Piladelapia, PA: Elsevier Saunders; 2018: chap 140.

ʻO Schafer AI. Nā maʻi thrombotic: nā mokuʻāina hypercoagulable. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 25th hua. Piladelapia, PA: Elsevier Saunders; 2016: chap 176.