Maʻi maʻi loli

ʻO ka maʻi loli liʻiliʻi ka maʻi hōʻino e hiki ai ke alakaʻi i ka maʻi nephrotic. ʻO ka nephrotic syndrome kahi hui o nā ʻōuli e pili pū me ka protein i ka mimi, nā pae protein o ke koko haʻahaʻa i ke koko, nā kiʻekiʻe kolesterol kiʻekiʻe, nā pae triglyceride kiʻekiʻe, a me ka pehu.

Hana ʻia kēlā me kēia puʻukū ma mua o hoʻokahi miliona mau ʻāpana i kapa ʻia he nephrons, ka mea e kānana i ke koko a hana i ka mimi.

I ka maʻi loli liʻiliʻi, aia ka ʻino o ka glomeruli. ʻO kēia nā kīʻaha koko liʻiliʻi ma loko o ka nephron kahi i kānana ʻia ke koko e hana i ka mimi a hemo ka ʻōpala. Loaʻa ka inoa o ka maʻi no ka mea ʻaʻole ʻike ʻia kēia pohō ma lalo o kahi microscope maʻamau. ʻIke wale ʻia ia ma lalo o kahi microscope mana loa i kapa ʻia he microscope electron.

ʻO ka maʻi loli liʻiliʻi ka kumu maʻamau o ka nephrotic syndrome i nā keiki. ʻIke ʻia ia i nā mākua me ka nephrotic syndrome, akā ʻoi aku ka liʻiliʻi.

ʻAʻole ʻike ʻia ke kumu, akā hiki mai ka maʻi ma hope a pili paha i:

• Nā hopena āpau
• Hoʻohana o NSAIDs
• Nā Tumors
• Hoʻomaha (flu a me ka pneumococcal, ʻoiai kakaikahi)
• Nā maʻi viral

Aia paha he mau hōʻailona o nephrotic syndrome, me:

• ʻO ka helehelena hua o ka mimi
• Makemake maikaʻi ʻole
• ʻO ka pehu (ʻo ka maka hoʻi, nā wāwae, a me nā kuʻekuʻe wāwae, a me ka ʻōpū)
• Loaʻa waiwai (mai ka paʻa ʻana o ka wai)

ʻAʻole hoʻemi ka maʻi liʻiliʻi i ka nui o ka mimi i hana ʻia. ʻAʻohe hele iki i ka holo ʻole o ka hakuʻala.

ʻAʻole hiki i ka mea mālama ola ke ʻike i nā hōʻailona o ka maʻi, ʻē aʻe o ka pehu. Hōʻike nā hōʻike koko a me ka mimi i nā hōʻailona o nephrotic Syndrome, me:

• Kolesterol kiʻekiʻe
• Nā pae kiʻekiʻe o ka protein i ka mimi
• Nā pae haʻahaʻa o ka albumin i ke koko

Hiki i kahi biopsy kidney a me ka nānā ʻana i nā kiko me ka microscope electron ke hōʻike i nā hōʻailona o ka maʻi loli iki.

Hiki i nā lāʻau i kapa ʻia ʻo Corticosteroids ke hoʻōla i ka maʻi liʻiliʻi i ka hapa nui o nā keiki. Pono paha kekahi mau keiki e noho ma nā steroid i mea e hoʻi ʻole ai ka maʻi.

Kūpono nā Steroids i nā mākua, akā ʻoi aku ka liʻiliʻi o nā keiki. Hiki paha i nā mākua ke hoʻi pinepine a lilo i ka hilinaʻi i nā steroid.

Inā maikaʻi ʻole nā ​​steroid, e manaʻo paha ka mea hāʻawi i nā lāʻau ʻē aʻe.

Hiki ke mālama ʻia ka pehu ʻana me:

• Nā lāʻau kaohi ACE
• Kaohi kaomi koko
• Diuretics (wai huaale)

ʻ toldlelo ʻia paha ʻoe e hōʻemi i ka nui o ka paʻakai i kāu papaʻai.

ʻOi aku ka maikaʻi o ka pane ʻana o nā keiki i nā corticosteroids ma mua o nā mākua. Pane pinepine nā keiki i loko o ka mahina mua.

Hiki i kahi hoʻi hou. Hiki ke hoʻomaikaʻi ke kūlana ma hope o ka mālama wā lōʻihi me nā corticosteroids a me nā lāʻau e kāohi i ka ʻōnaehana pale (nā pale pale pale).

Kāhea i kāu mea hāʻawi inā:

• Hoʻolālā ʻoe i nā ʻōuli o ka maʻi loli liʻiliʻi
• Loaʻa iā ʻoe kēia maʻi a ʻoi aku ka maikaʻi o kāu mau ʻōuli
• Hoʻolālā ʻoe i nā ʻōuli hou, me nā hopena o nā lāʻau i hoʻohana ʻia e mālama ai i ka maʻi

Hoʻololi iki i ka maʻi nephrotic; Maʻi Nil; Lipoid nephrosis; Idiopathic nephrotic maʻi pale o ka wā kamaliʻi

• ʻO Glomerulus a me nephron

ʻO Appel GB, Radhakrishnan J, DʻAgati VD. Maʻi glomerular lua. I: Yu ASL, Chertow GM, Luyckx VA, Marsden PA, Skorecki K, Taal MW, eds. ʻO Brenner a me Rector's The Kidney. 11th hua. Piladelapia, PA: Elsevier; 2020: chap 32.

ʻO Erkan E. Nephrotic maʻi maʻi. I: Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, eds. ʻO Puka Textbook of Pediatrics ʻo Nelson. 21st ed. Piladelapia, PA: Elsevier; 2020: chap 545.