ʻO glomerulosclerosis segmental mākā

ʻO ka glomerulosclerosis ʻāpana kikoʻī kahi ʻili maka i ka wae kānana o ka puʻupaʻa. Kapa ʻia kēia ʻano ʻo glomerulus. Mālama ka glomeruli i mau kānana e kōkua i ke kino e hoʻopau i nā mea ʻino. He tausani glomeruli ko kēlā me kēia hakuʻala.

"Focal" ʻo ia hoʻi, lilo kekahi o ka glomeruli i scarred. Noho mau ka poʻe ʻē aʻe. "Segmental" ʻo ia hoʻi, ʻāpana wale nō o kahi glomerulus pākahi i hōʻino ʻia.

ʻO ke kumu o ka glomerulosclerosis segmental focal ʻike pinepine ʻole ʻia.

Hoʻopili ke ʻano i nā keiki a me nā mākua. Kū pinepine pinepine ia i nā kāne a me nā keikikāne. ʻOi aku ka maʻamau i nā ʻAmelika ʻAmelika. Mālama ka glomerulosclerosis segmental i ka hapahā o nā hihia āpau o ka nephrotic syndrome.

ʻO nā kumu i ʻike ʻia e hoʻopili ʻia:

• Nā lāʻau e like me heroin, bisphosphonates, anabolic steroid
• Maʻi kīnā
• Hoʻopilikia i nā pilikia pili koko
• Ka momona
• Reflux nephropathy (kahi ʻano e kahe ka hoʻi o ka mimi mai ka pale a i ka puʻupaʻa)
• Maʻi maʻi maʻi maʻi
• ʻO kekahi mau lāʻau

Pākuʻi ʻia paha nā ʻōuli:

• Mimi hua (mai ka nui o ka protein i ka mimi)
• Makemake maikaʻi ʻole
• ʻO Swelling, i kapa ʻia he edema laulaha, mai nā wai i paʻa i ke kino
• Kaumaha hoʻonui

E hana ka mea mālama ola i kahi hoʻokolohua kino. Hiki i kēia hoʻokolohua ke hōʻike i ka pehu o nā mea (edema) a me ke kiʻekiʻe o ke koko. Hiki ke hoʻomohala i nā ʻōuli o ke kōpaʻa (ʻākāhā) a me ka nui o ka wai i ke ʻano o ka ʻino.

E komo pū paha nā hoʻāʻo:

• ʻO Biopsy hakuʻala
• Nā ho'āʻo hana hakuʻala (ke koko a me ka mimi)
• Urinalysis
• Mīkini paʻi mimi
• Pīmī protein

Hiki i nā mālama ke hoʻopili:

• ʻO nā lāʻau e hōʻemi i ka pane o ke kino i ka pane.
• ʻO nā lāʻau e hoʻohaʻahaʻa i ke kahe o ke koko. Kōkua kekahi o kēia mau lāʻau i ka hoʻoliʻiliʻi i ka nui o nā protein i ninini ʻia i ka mimi.
• Nā lāʻau lapaʻau e hoʻopau ai i ka nui o ka wai (diuretic a i ʻole "pila wai").
• ʻO kaʻai sodium haʻahaʻa e hōʻemi ai i ka pehu ʻana a hoʻohaʻahaʻa i ke koko.

ʻO ka pahuhopu o ka mālama ʻana ka kaohi ʻana i nā ʻōuli o nephrotic Syndrome a pale i ka holo pono ʻole ʻana o ke kīnā ʻole. Pākuʻi ʻia paha kēia mau ʻano mālama ʻana:

• Nā lāʻau Antibiotics e kaohi i nā maʻi
• Pākuʻi loli
• ʻAi momona momona
• Papaʻai haʻahaʻa a haʻahaʻa paha
• Pākuʻi wikamina D
• Dialysis
• Ke kuʻi ʻōhua

ʻO kahi ʻāpana nui o ka poʻe me ka glomerulosclerosis focal a i ʻole segmental e hoʻomohala i ka hōʻino kīnā ʻole mau.

Komo pū nā pilikia:

• Ka hōʻeha kīnā ʻole
• ʻO ka maʻi hōʻeha hope loa
• Maʻi kīnā
• Kaʻai pono ʻole
• Nā maʻi Nephrotic

Kāhea i kāu mea hāʻawi inā hoʻomohala ʻoe i nā ʻōuli o kēia ʻano, keu hoʻi inā aia:

• Fiva
• ʻEha me ka urination
• Hoʻoemi i ka puka mimi

ʻAʻole ʻike ʻia kahi pale.

Glomerulosclerosis ʻāpana; Sclerosis kālele ana me hyalinosis

• ʻŌnaehana mimi kāne

ʻO Appel GB, DʻAgati VD. ʻO ke kumu a me ke kula kiʻekiʻe (non-genetic) ke kumu o ka glomerulosclerosis focal and segmental. I: Feehally J, Floege J, Tonelli M, Johnson RJ, eds. Nā Nephrology Haumāna piha. ʻElua huaʻōlelo Piladelapia, PA: Elsevier; 2019: chap 18.

ʻO Appel GB, Radhakrishnan J. Nā maʻi Glomerular a me nā nephrotic syndrome. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil.25th hua. Piladelapia, PA: Elsevier Saunders; 2016: chap 121.

Pendergraft WF, Nachman PH, Jennette JC, Falk RJ. Maʻi glomerular mua. I: Skorecki K, Taal MW, Chertow GM, Marsden PA, Yu ASL, eds. ʻO Brenner a me Rector's The Kidney. 10 o ka lā. Piladelapia, PA: Elsevier Saunders; 2016: chap 32.