Kalipona pyrophosphate arthritis

ʻO ka calcium pyrophosphate dihydrate (CPPD) kahi maʻi hui pū kekahi e hiki ke hoʻouka i nā maʻi o ke kuamoʻo. E like me ka gout, nā aniani i loko o nā hono. Akā i kēia arthritis, ʻaʻole i hoʻokumu ʻia nā aniani mai ka uric acid.

ʻO ka waiho ʻana o ka calcium pyrophosphate dihydrate (CPPD) ke kumu o kēia ʻano arthritis. ʻO ke kūkulu ʻana o kēia mea hana kemika i nā aniani i ka cartilage o nā hono. ʻO kēia ke alakaʻi aku nei i nā hoʻouka ʻana o ka huʻi pū a me ka ʻeha o nā kuli, nā pūlima, nā kuʻekuʻe wāwae, nā poʻohiwi a me nā hono ʻē aʻe. ʻOkoʻa ka gout, ʻaʻole pili ka metatarsal-phalangeal ami o ka manamana nui.

Ma waena o nā poʻe mākua, he kumu maʻamau ka CPPD o ka maʻi pākī (huʻi) i hoʻokahi hui. Hoʻokumu ʻia kēia hoʻouka e:

• Ka hōʻeha i ka hui
• Hyaluronate ka pahu kui i ka hui
• Maʻi maʻi

Hoʻopili nui ka ʻōpala CPPD i ka ʻelemakule ma muli o ka hoʻonui ʻana o ka degeneration a me ka osteoarthritis me ka makahiki. Hoʻonui ka poino hui like i ka ʻano o ka waiho ʻana o CPPD. Eia nō naʻe, hiki i ka CPPD arthritis ke hoʻopili i ka poʻe ʻōpio i loaʻa nā kūlana e like me:

• Hemochromatosis
• Maʻi Parathyroid
• Hewa ʻōiwi kīnā ʻole ʻo Dialysis

I ka hapanui o nā hihia, ʻaʻole kumu ʻo CPPD arthritis i kekahi ʻōuli. Akā, hōʻike nā x-ray o nā hono i hoʻopili ʻia e like me nā kuli e hōʻike i nā waihona o ka calcium.

ʻO kekahi poʻe me nā waihona CPPD mau i nā hono nui i loaʻa i kēia mau ʻōuli:

• ʻEha
• ʻŌhū
• Mahana
• ʻUlaʻula

Hiki ke hala i nā ʻeha hui pū no nā mahina. ʻAʻohe paha hōʻailona ma waena o nā hoʻouka.

I kekahi poʻe CPPD arthritis ke kumu o ka hōʻino nui i kahi hui.

Hiki pū kekahi ke kuʻi CPPD i ka iwikuamoʻo, ma lalo a ma luna hoʻi. ʻO ke kaomi ʻana i nā ʻalalā iwi e ʻeha ai nā lima a me nā wāwae.

Ma muli o ka like o nā ʻōuli, hiki ke huikau ʻo CPPD arthritis me:

• Gouty arthritis (gout)
• ʻO Osteoarthritis
• Rheumatoid arthritis

Hōʻike ka hapa nui o nā kūlana arthritic i nā ʻōuli like. ʻO ka hoʻāʻo ʻana i ka wai hui no nā aniani hiki ke kōkua i ke kauka e ʻike i ke ʻano.

Hiki iā ʻoe ke hana i nā hōʻike aʻe:

• ʻO ka hoʻāʻo ʻana o ka wai hui e ʻike i nā aʻa koko keʻokeʻo a me nā aniani kalipona pyrophosphate
• Hoʻohui nā x-ray e nānā no ka hōʻino hui a me nā waihona calcium i nā wahi i hui ʻia
• ʻO nā hoʻokolohua kiʻi ʻē aʻe e like me CT scan, MRI a i ʻole ultrasound, inā koi ʻia
• ʻO nā hoʻokolohua koko e kānana no nā ʻano e hoʻopili ʻia i ka maʻi kō pyrophosphate calcium

Hoʻopili paha ka mālama ʻana i ka hoʻoneʻe ʻana i ka wai e hoʻōla i ke kaomi o ka ami. Hoʻokomo ʻia kahi nila i loko o ka ami a makemake nui ʻia ka wai. ʻO kekahi mau koho lapaʻau maʻamau:

• Nā kōkō steroid: e mālama pono i nā hono pehu
• ʻO nā mea steroid oral: e mālama i nā hono pehu āpau
• Nā lāʻau anti-inflammatory Nonsteroidal (NSAIDs): e hoʻomāmā i ka ʻeha
• Colchisin: e mālama i nā hōʻeha o CPPD arthritis
• No ka maʻi CPPD maʻi mau i nā hui like methotrexate a i ʻole hydroxychloroquine kōkua paha

Hana maikaʻi ka hapa nui o ka poʻe me ka mālama ʻana e hōʻemi i ka ʻeha hui pū. Hiki i kahi lāʻau e like me colchinika ke kōkua i ka pale ʻana i nā hoʻouka hou ʻana. ʻAʻohe mālama e wehe i nā aniani CPPD.

Hiki ke hana ʻino paʻa paʻa me ka ʻole o ka lāʻau.

Kāhea i kāu mea mālama ola inā loaʻa iā ʻoe nā hōʻeha o ka huʻihuʻi a me ka ʻeha pū.

ʻAʻohe ala i ʻike ʻia e pale ai i kēia maʻi. Eia nō naʻe, mālama ʻana i nā pilikia ʻē aʻe i hiki i ka hopena o ka CPPD arthritis e hoʻoliʻiliʻi loa ai ke ʻano.

Hiki i nā kipa ukali maʻamau ke pale i ka hōʻino mau o nā hono i hoʻopili ʻia.

ʻO ka maʻi kalipona pyrophosphate dihydrate maʻi; Maʻi CPPD; Huʻi / maʻi CPPD arthritis; Pseudogout; Pyrophosphate arthropathy; ʻO Chondrocalcinosis

• Huʻi hui ʻapo
• ʻO Osteoarthritis
• ʻO ke ʻano o kahi ami

Andrés M, Sivera F, Pascual E. Therapy no CPPD: nā koho a me nā hōʻike. ʻO Curr Rheumatol Rep. 2018; 20 (6): 31. PMID: 29675606 pubmed.ncbi.nlm.nih.gov/29675606/.

ʻO Edwards NL. Nā maʻi waiho Crystal. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 257.

ʻO Terkeltaub R. Ka maʻi aniani calcium: calcium pyrophosphate dihydrate a me ka phosphate calcium. I: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, nā hua. ʻO Kelley lāua ʻo Firestein's Bookbook of Rheumatology. 10 o ka lā. Piladelapia, PA: Elsevier; 2017: chap 96.