Mea Kākau: Janice Evans
Lā O Ka Hana: 26 Iulai 2021
HōʻAno Hou I Ka Lā: 16 Nowemapa 2024
Anonim
Multiple Endocrine Neoplasia (MEN)
Wikiō: Multiple Endocrine Neoplasia (MEN)

ʻO ka neoplasia endocrine Multiple (MEN) ʻano I kahi maʻi kahi o kahi a ʻoi aku paha o nā endocrine glands i hana nui a hana paha i kahi tumo. Ua hoʻoili ʻia i loko o nā ʻohana.

Hoʻopili pinepine nā gland Endocrine i:

  • ʻO Pancreas
  • ʻO Parathyroid
  • Pituitary

Hoʻokumu ʻia ʻo MEN I e kahi kīnā i loko o kahi ʻāpana e hāpai i ke code no ka protein i kapa ʻia menin. Kuhi ke ʻano i nā hikoko o nā glands like ʻole i ka mea like, akā ʻaʻole pono i ka manawa like.

Hiki ke hana i ka maʻi i kēlā me kēia makahiki, a pili like ia i nā kāne a me nā wahine. Hāpai kahi moʻolelo ʻohana o kēia maʻi i kou makaʻi.

Hoʻololi nā ʻōuli i kēlā me kēia kanaka, a kaukaʻi ʻia i ka gland. Pākuʻi ʻia lākou:

  • Abdominal eha
  • Hopohopo
  • ʻEleʻele, noho aliʻi
  • Manaʻo Bloated ma hope o ka pāʻina ʻana
  • ʻO ke puhi ʻana, ʻehaʻeha ʻana, a i ʻole pōloli pōpilikia ma ka ʻōpū o luna a i ʻole ka umauma i lalo i hoʻomaha ʻia e nā antacids, ka waiū, a me nā meaʻai.
  • Hoemi i ka hoihoi wahine
  • Ka luhi
  • ʻEha poʻo
  • Ka nele o nā menstrual wā (i nā wahine)
  • Loaʻa ka ʻai ʻole
  • Ka nalowale o ke kino a i ʻole ka helehelena maka (i nā kāne)
  • Hoʻololi manaʻo a huikau paha
  • ʻEha ʻeha
  • ʻO Nusea a me ka luaʻi
  • ʻIke i ke anuanu
  • Ka hoʻohaʻahaʻa kaumaha ʻole
  • Nā pilikia ʻike
  • Nawaliwali

E hana ka mea mālama ola i kahi hoʻokolohua kino a nīnau i nā nīnau e pili ana i kāu mōʻaukala a me nā hōʻailona. E hana ʻia paha kēia mau hoʻāʻo:


  • Pae pae cortisol
  • CT scan o ka ʻōpū
  • CT scan o ke poʻo
  • ʻO ka kō kō kō
  • Ke hoʻāʻo genetic
  • Hōʻike insulina
  • MRI o ka ʻōpū
  • MRI o ke poʻo
  • ʻO ka hormonone adrenocorticotropic serum
  • Kalipuna serum
  • ʻO ka hormone follicle hoʻonāukiuki
  • Gas gastrin
  • Serum glukagon
  • ʻO ka hormone luteinizing serum
  • ʻO ka hormonone parathyroid serum
  • ʻO ka prolactin serum
  • ʻO ka hormone hoʻouluulu thyroid
  • Ultrasound o ka ʻāʻī

ʻO keʻoki e wehe i ka momona maʻi pinepine ka mālama ʻana i nā koho. Hiki ke hoʻohana ʻia kahi lāʻau i kapa ʻia bromocriptine ma kahi o ke kahakaha ʻana no nā pituitary tumors e hoʻokuʻu i ka hormone prolactin.

Hiki ke hemo i nā gland parathyroid, ka mea e kaohi ai i ka hana kalima. Eia nō naʻe, paʻakikī i ke kino e hoʻoponopono i nā pae o ka calcium me ka ʻole o kēia mau glands, no laila ʻaʻole hana mua ʻia kahi huakaʻi parathyroid āpau i ka nui o nā hihia.

Loaʻa ka lāʻau lapaʻau e hoʻemi i ka nui o ka hana ʻana o ka ʻōpū o ka ʻōpū i hoʻokumu ʻia e kekahi mau tumors (gastrinomas), a e hōʻemi i ka makaʻala o nā maʻi puʻupuʻu.


Hāʻawi ʻia ka Hormone replacement therapy ke lawe ʻia nā glands holoʻokoʻa a hana ʻole paha i nā hormona.

ʻO nā maʻi pituitary a me parathyroid he noncancerous (benign), akā hiki i kekahi mau tumite pancreatic ke lilo i maʻi maʻi (malignant) a hohola i ke ake. Hiki i kēia mau mea ke hoʻohaʻahaʻa i ke kali ola.

ʻO nā ʻōuli o ka maʻi ulcer peptic, kō kō ke kō, me ka nui o ka calcium i loko o ke koko, a pane pinepine ka hana pituitary i ka lapaʻau kūpono.

Hiki ke hoʻi hou i nā tumors. Pili nā ʻōuli a me nā pilikia ma luna o nā glands e hoʻopili ai. Pono pono nā loiloi maʻamau e kāu mea hāʻawi.

Kāhea i kāu mea hāʻawi inā ʻike ʻoe i nā ʻōuli o MEN I a i ʻole he moʻolelo ʻohana ko kēia ʻano.

Paipai ʻia nā ʻohana pili pili o ka poʻe i hoʻopilikia ʻia me kēia maʻi.

Wermer maʻi maʻi; NA KANAKA I

  • Nānā Endocrine

Pūnaewele Pūnaewele Manuahi Manuahi. Nā kulekele hana lapaʻau i ka oncology (NCCN guideine): neuroendocrine tumors. Mana 1.2019. www.nccn.org/professionals/physician_gls/pdf/neuroendocrine.pdf. Hoʻohou ʻia Malaki 5, 2019. Loaʻa ʻia ma Malaki 8, 2020.


Newey PJ, Thakker RV. Neoplasia endocrine lehulehu. I: Melmed S, Auchus RJ, Goldfine AB, Koenig RJ, Rosen CJ, eds. ʻO Williams Textbook of Endocrinology. 14th ed. Piladelapia, PA: Elsevier; 2020: chap 42.

Nieman LK, Spiegel AM. Nā maʻi Polyglandular. I: Goldman L, Schafer AI, eds. ʻO ka lāʻau lapaʻau Goldman-Cecil. 26th ed. Piladelapia, PA: Elsevier; 2020: chap 218.

ʻO Thakker RV. ʻO nā neoplasia endocrine lehulehu 1. I: Jameson JL, De Groot LJ, de Kretser DM, et al, eds. Endocrinology: Makua a Pediatric. ʻEpekema 7 Piladelapia, PA: Elsevier Saunders; 2016: chap 148.

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