ʻO Vincristine: he aha ia, he aha ia a me nā hopena ʻaoʻao

Anter

• No ke aha ia
• Pehea e ho ohana
• Nā Kūʻai Kūʻai
• Nā hopena ʻē aʻe

ʻO Vincristine ka mea hana i loko o kahi lāʻau antineoplastic i ʻike ʻia ma ke ʻano kālepa ʻo Oncovin, i hōʻike ʻia no ka mālama ʻana i nā ʻano like ʻole o ka maʻi ʻaʻai, e like me leukemia, lung a me ka maʻi ʻaʻai umauma.

ʻO kāna hana e hoʻopilikia i ka metabolism o nā amino acid a pale i ka hoʻokaʻawale ʻana o ka pūnaewele, e hoʻemi ana i ka likelika o ka maʻi ʻaʻai e laha ana ma ke kino.

Loaʻa kēia lāʻau lapaʻau ma ke ʻano he injection a pono e lawelawe ʻia e kahi ʻoihana olakino.

No ke aha ia

ʻO kahi lāʻau lāʻau i hōʻike ʻia no ka mālama ʻana i nā ʻano maʻi ʻaʻai e like me:

• Leukemia lymphoid huikau;
• Neuroblastoma;
• ʻŌiwi ʻo Wilms;
• Maʻi ʻaʻai umauma;
• Maʻi ʻaʻai puʻu;
• Maʻi ʻaʻai Ovary;
• Maʻi ʻaʻai cerviery;
• Maʻi ʻaʻai kala;
• ʻO Hodgkin's a me non-Hodgkin's lymphoma;
• ʻO sarweka a Ewing;
• Osteosarcoma;
• Melanoma malignant.

Hoʻohui ʻia, hōʻike ʻia kēia lāʻau no ka mālama ʻana i nā mycosis fungoides a me idiopathic thrombocytopenic purpura. E aʻo he aha ia a pehea e ʻike ai i nā ʻōuli o ka idiopathic thrombocytopenic purpura.

Pehea e ho ohana

Pono e lawelawe i kēia lāʻau i intravenously, e kekahi ʻoihana olakino, a me ka mahele lāʻau a me ka manawa o ka lapaʻau e hoʻoholo ʻia e ka oncologist.

Ma ke ʻano laulā, penei ke ana:

Nā mākua

• 0.01 a 0.03 mg o Vincristine no kg o ke kaumaha o ke kino, ma ke ʻano hoʻokahi mahele lāʻau, i kēlā me kēia 7 lā.

Kamaliʻi

• Ma luna o 10 kg: lawelawe i 1.5 a 2 mg o Vincristine ma ka mika mika o ka ʻili o ke kino, ma ke ʻano he mahele lāʻau, i kēlā me kēia 7 lā;
• Me ka 10 kg a ʻoi iki paha: lawelawe i 0.05 mg o Vincristine no kg o ke kaumaha o ke kino, ma ke ʻano hoʻokahi mahele lāʻau, i kēlā me kēia 7 lā.

ʻO ka lōʻihi o ka mālama ʻana e hoʻoholo ʻia e ka oncologist.

Nā Kūʻai Kūʻai

Hoʻopaʻa ʻia kēia lāʻau no ka poʻe me ka hypersensitivity i nā ʻāpana o ka haʻilula a i nā mea maʻi me ka maʻi demyelinating o Charcot-Marie-Tooth syndrome.

Eia hou, ʻaʻole pono e hoʻohana ʻia e nā wahine hāpai a me nā wahine e hānai ana i nā waiū e hoʻopau i ka lactation i ka wā o ka mālama ʻana me vincristine.

Nā hopena ʻē aʻe

ʻO kekahi o nā hopena maʻamau i hiki ke hana ʻia i ka wā o ka mālama ʻana me vincristine ka nalowale ʻana o ka lauoho, ka paʻa paʻa ʻana, ka ʻeha o ke kino, ka hoʻēmi ʻana i nā aʻa koko keʻokeʻo, ka nalowale ʻana o ka naʻau, ka paʻakikī e hele a me ka nalo ʻana o nā reflexes.

ʻO nā hopena ʻē aʻe i hiki ke hana ʻia he maʻi neuromuscular.