No ke aha ʻo Trimetazidine?

Anter

• Pehea e ho ohana
• He aha ke ʻano o ka hana
• ʻO wai ka mea pono ʻole e hoʻohana
• Nā hopena ʻē aʻe

ʻO Trimetazidine kahi mea hana i hōʻike ʻia no ka mālama ʻana i ka puʻuwai ischemic a me ka maʻi puʻuwai ischemic, kahi maʻi i hoʻokumu ʻia e ka hemahema o ke kahe o ke koko i nā aʻa.

Hiki ke kūʻai ʻia ʻo Trimetazidine i nā hale kūʻai lāʻau no kahi kumukūʻai ma kahi o 45 a 107 mau reais, ke hōʻike ʻia kahi palapala kuhikuhi.

Pehea e ho ohana

ʻO ka mea i koi ʻia ʻo 1 papa o 35 mg, ʻelua manawa i ka lā, hoʻokahi manawa i ke kakahiaka, i ka wā o ka ʻaina kakahiaka a i hoʻokahi manawa i ke ahiahi, i ka wā o ka ʻaina awakea.

He aha ke ʻano o ka hana

Mālama ʻo Trimetazidine i ka ikehu metabolism o nā hunaola ischemic, i hōʻike ʻia i ka hoʻohaʻahaʻa oxygen, e pale ana i ka hōʻemi ʻana o nā pae intracellular o ATP (ikehu), no laila e hōʻoia ana i ka hana kūpono o nā pauma ionic a me ke kahe o ka sodium a me ka potassium, ʻoiai e mālama ana i ka cell homeostasis.

Loaʻa kēia mālama ʻana o ka ikehu metabolism ma o ka pāpā ʻana i ka β-oxidation o nā wai momona, hana ʻia e trimetazidine, kahi e hoʻonui ai i ka hoʻohaʻahaʻa o ka glucose, kahi ala e loaʻa ai ka ikehu e koi ai i ka liʻiliʻi o ka oxygen e hoʻohālikelike ʻia i ka hana β-oxidation. No laila, ʻo ka potentiation o ka glucose oxidation e hoʻonui i ka hana ikehu cellular, e mālama ana i ka metabolism ikehu kūpono i ka manawa o ka ischemia.

I nā maʻi me ka maʻi puʻuwai ischemic, hana ʻo trimetazidine ma ke ʻano he metabolic agents e mālama nei i nā pae intracellular o myocardial high phosphates ikaika.

ʻO wai ka mea pono ʻole e hoʻohana

Hoʻopili ʻia kēia lāʻau i loko o nā mea maʻi me ka hypersensitivity e trimetazidine a i ʻole kekahi o nā ʻāpana o ke kumumanaʻo, nā kānaka me ka maʻi ʻo Parkinson, nā ʻōuli o ka parkinsonism, nā haʻalulu, nā wāwae wāwae hoʻomaha ʻole a me nā hoʻololi ʻē aʻe e pili ana i ka neʻe ʻana a me ka hōʻeha ʻana o ka puʻuwai nui me ka cleinine clearance ma lalo o 30mL. / min.

Hoʻohui ʻia, ʻaʻole pono e hoʻohana ʻia kēia lāʻau lapaʻau e nā keiki ma lalo o 18, nā wahine hāpai a i ʻole nā ​​wahine hānai.

Nā hopena ʻē aʻe

ʻO kekahi o nā hopena ʻē aʻe i hiki ke hana ʻia i ka wā o ka mālama ʻana me trimetazidine ʻo ka puʻupuʻu, ka ʻeha o ka ʻeha, ka ʻeha o ka ʻōpū, ka maʻi diarrhea, ka ʻai maikaʻi ʻole, ka pīhoihoi, ka luaʻi, ka pehu, ka huehue, ka hives a me ka nāwaliwali.