Ke hoʻokolohua pololei a pololei ʻole o ka coomb: he aha ia a he aha ia

Anter

• Pehea e pau ai ka hōʻike
• He aha ke ʻano o ka hopena

ʻO ka hoʻokolohua coomb kahi ʻano o ka hoʻāʻo koko e loiloi i ke kū ʻana o nā mea ʻino kikoʻī e hoʻouka i nā hunaola ʻulaʻula, e hopena ana i ko lākou luku a hiki i ke ʻano o kahi ʻano anemia i kapa ʻia ʻo hemolytic.

ʻElua ʻano nui o kēia hōʻike, e hoʻopili ana:

• Hōʻike Coombs pololei: loiloi pololei i nā hunaola ʻulaʻula, e nānā ana i nā mea ʻino i hoʻopili ʻia i ka hunaʻulaʻula a inā paha i loaʻa ʻia kēia mau mea ʻino mai ka ʻōnaehana pale pilikino o ke kanaka a i ʻole i loaʻa ʻia e transfusion. Hana ʻia kēia hōʻike e ʻike i nā anemias hemolytic autoimmune - E ʻike i nā hōʻailona e hōʻike ai i ka hemolytic anemia;
• Hōʻike Coombs Indirect: Loiloi i ke koko serum, e hoʻomaopopo ana i nā mea ʻino i loaʻa ma laila, a noi pinepine ʻia i nā hanana o ke transfusion, e hōʻoia i ke kūlike o ke koko e hāʻawi ʻia me ka mea e loaʻa ana.

Ma waho aʻe o ka anemia, hiki i kēia hoʻokolohua ke kōkua i ka ʻike ʻana i nā maʻi ʻē aʻe e pili ana i nā huna koko e like me leukemia, lupus, mononucleosis a me nā fetry erythroblastosis, ʻo ia hoʻi ka maʻi hemolytic o ka hānau hou, a me ka ʻike ʻana i ka makaʻu o ka transfusion react. E aʻo hou aʻe e pili ana i ka erythroblastosis fetal.

Pehea e pau ai ka hōʻike

Hana ʻia ka hoʻāʻo Coombs mai kahi hāpana koko, a pono e hōʻiliʻili ʻia i loko o kahi keʻena hoʻokolohua hoʻokolohua hoʻokolohua. Hoʻouna ʻia ke koko i hōʻiliʻili ʻia i ke keʻena hoʻokolohua, kahi e hana pololei ʻia ai nā hoʻokolohua a Coombs pololei, kaukaʻi ʻia i ke kumu

I ka hoʻokolohua Coombs pololei, hoʻohui ʻia ka reagent Coombs i ke koko o ka mea maʻi, e ʻae ana i ka ʻike ʻana o nā mea pale i hoʻohui ʻia i nā hunaola ʻulaʻula. I ka hōʻike Coombs ʻole, hōʻiliʻili ʻia ke koko a centrifuged, e hoʻokaʻawale ana i nā hunaola ʻulaʻula mai ka serum, kahi e loaʻa ai nā mea ʻino. I ke serum, hoʻohui ʻia nā hunaola ʻulaʻula me nā lāʻau ʻino i mea e hōʻoia ai inā aia nā autoantibodies i loko o ke serum, a no laila, i ke koko o ka mea maʻi.

No ka hoʻokō ʻana i ka hōʻike Coombs, ʻaʻole pono kahi hoʻomākaukau, akā hiki i kekahi mau lāʻau ke hoʻopilikia i ka hopena, no laila he mea nui e hoʻomaopopo i ke kauka e pili ana i kāna hoʻohana i hiki ai ke hāʻawi ʻia ke alakaʻi ma kāna kau ʻia ʻana.

He aha ke ʻano o ka hopena

He maikaʻi ʻole ka hopena o nā hōʻike Coombs ke loaʻa ʻole kahi antibody i kumu e luku ai i nā ʻulaʻula poepoe, ʻo ia ke kumu i manaʻo ʻia he hopena maʻamau ia.

Eia nō naʻe, inā maikaʻi ka hopena, ʻo ia hoʻi he antibody i loko o ke koko a, no laila, inā maikaʻi ka hopena ma nā hōʻike Coombs pololei ʻo ia hoʻi he maʻi paha kā ke kanaka e like me:

• Anemia hemolytic autoimmune;
• Maʻi ʻaʻai e Mycoplasma sp.;
• Syphilis;
• Leukemia;
• Lupus erythematosus;
• Mononucleosis.

I ke ʻano o kahi hoʻokolohua Coombs ʻole, ʻo ka hopena maikaʻi ke ʻano he antibody ke kanaka i hiki ke hana i nā clots ke loaʻa iā ia kekahi ʻano o ke koko a, no laila, pono e akahele i ka hana ʻana o ke kō.

I kekahi hihia, he mea nui mau ka loiloi i ka hopena e ke kauka nāna i noi no ia, ʻoiai hiki i kekahi ʻano o ke kanaka ke hoʻololi i ka hopena.