Ka lāʻau i kau ʻia no ka maʻi ʻaʻai ʻoi loa: 7 mau mea e ʻike

Anter

• 1. He aha nā therapies i hoʻolālā ʻia?
• 2. Pehea e ʻokoʻa ai ka hoʻomoana hoʻomākaukau ʻia mai ka chemotherapy maʻamau?
• 3. Pehea e hoʻomohala ʻia ai nā therapies i hoʻolālā ʻia?
• 4. He aha nā therapies i hoʻolālā ʻia i ʻāpono ʻia a pehea e hana ai?
• 5. ʻO wai ka moho no ka therapeutical target?
• 6. Aia kekahi mau palena o ka hoʻomōhala hoʻomōhala?
• 7. He aha nā hopena āpau o ka therapeutical target?

ʻO nā ʻike hou i ka genome maʻi ʻaʻai i alakaʻi ʻia i nā ʻano lāʻau hoʻomōhala hou he nui no ka maʻi ʻaʻai umauma holomua. Kuhi kēia kahua hoʻohiki o ka mālama ʻana i ka maʻi ʻaʻai a hōʻeha i nā hunaola maʻi ʻaʻai me ka maikaʻi loa. Eia nā mea ʻehiku āu e pono ai e ʻike e pili ana i kēia hui hou o nā lāʻau lapaʻau kikoʻī.

1. He aha nā therapies i hoʻolālā ʻia?

Hoʻohana nā therapies i kau ʻia i ka ʻike e pili ana i kāu genes a me nā protein e pale, ʻike pono, a mālama i ka maʻi ʻaʻai. Kūpono nā therapies e hoʻouka i nā hunaola maʻi ʻaʻai me ka ʻole o ka hōʻeha ʻana i nā hunaola olakino.

2. Pehea e ʻokoʻa ai ka hoʻomoana hoʻomākaukau ʻia mai ka chemotherapy maʻamau?

Hana ka chemotherapy maʻamau i ka luku ʻana i nā ʻelua maʻamau a me ka hoʻokaʻawale wikiwiki ʻana i nā hunaola maʻi ʻaʻai. Hoʻolālā ʻia nā mea i hoʻolālā ʻia e pale i ka hoʻolaha ʻana o nā māka molekula e pili ana i ka maʻi ʻaʻai.

ʻOkoʻa nā hunaola ʻaukā i nā hunaola olakino. Hiki i nā hoʻoponopono i hoʻopaʻa ʻia ke huki i nā hunaola maʻi ʻaʻai a laila luku a pale paha i ko lākou ulu ʻana me ka ʻole o ka hōʻeha ʻana i nā hunaola maʻi ʻole. Manaʻo ʻia kēia ʻano lapaʻau he ʻano chemotherapy, ʻoiai he ʻokoʻa ka hana. ʻOi aku ka nui o nā hopena i loaʻa i nā therapies māka ʻia ma mua o nā lāʻau chemotherapy maʻamau.

3. Pehea e hoʻomohala ʻia ai nā therapies i hoʻolālā ʻia?

ʻO ka hana mua i ka hoʻomohala ʻana i kahi lāʻau i hoʻomākaukau ʻia e ʻike i nā māka mole e hana nui i ka ulu ʻana o ka maʻi ʻaʻai a me ke ola. I ka manawa e ʻike ʻia ai kahi māka, hoʻomohala ʻia kahi therapy e hoʻopilikia ai i ka hana a i ʻole ke ola ʻana o nā hunaola maʻi ʻaʻai. Hiki ke hana i kēia ma ka hoʻoliʻiliʻi ʻana i ka hana o ka māka a pale paha iā ia mai ka hoʻopaʻa ʻana i kahi mea loaʻa e hana maʻamau.

4. He aha nā therapies i hoʻolālā ʻia i ʻāpono ʻia a pehea e hana ai?

• Nā hōʻailona Hormone lohi a hoʻōki paha i ka ulu ʻana o nā tumora pili i ka hormon e koi i kekahi mau hormoni e ulu.
• Nā mea kāohi transduction hōʻailona ālai i nā hana o nā mole i komo i ka transduction hōʻailona, ​​ke kaʻina hana e pane ai kahi pūnaewele i nā hōʻailona mai kona wahi.
• ʻO nā mea hoʻohālikelike Gene expression(GEM) hoʻololi i ka hana o nā protein i hana i ka mālama ʻana i ka manaʻo o ka ʻāpana.
• Nā mea hoʻokomo Apoptosis hana i nā hunaola maʻi ʻaʻai e loaʻa i ka apoptosis, ke kaʻina hana o ka make ʻana o ke koleke.
• Nā mea kāohi Angiogenesis ālai i ka ulu ʻana o nā kīʻaha koko hou, a laila kaohi ʻana i ka lako o ke koko e pono ai e ulu nā tumors.
• Nā Immunotherapies hoʻonāukiuki i ka ʻōnaehana pale pale e luku ai i nā hunaola maʻi ʻaʻai.
• Nā monemona monoclonal (mAb a i ʻole moAb) hāʻawi i nā molikō ʻawahia e māka a pepehi i nā hunaola maʻi ʻaʻai ma ke ʻano e like me ka magnet e loaʻa a iā lākou a ālai i kā lākou hana hou ʻana.

5. ʻO wai ka moho no ka therapeutical target?

Ke ʻae ʻia e ka US Food and Drug Administration kahi ʻano i hoʻomākaukau hoʻomohala ʻia, wehewehe lākou i nā ʻano kikoʻī ke hiki ke hoʻohana ʻia. Hoʻomaopopo pū lākou i ka mea kūpono no ka lāʻau. Ma ke ʻano laulā, hoʻohana ʻia nā therapies i hoʻomākaukau ʻia e mālama ai i ka poʻe i loaʻa kahi ʻano hoʻololi e hiki ke ʻike ʻia e ka lāʻau. Hana lākou e luku a pāpā paha i nā hunaola maʻi ʻaʻai o kēlā hoʻololi. He koho nō hoʻi ia no ka poʻe i loaʻa ʻole ka maʻi ʻaʻai i nā ʻano lāʻau ʻē aʻe, ua laha, a ʻaʻole kūpono i ke ʻoki.

6. Aia kekahi mau palena o ka hoʻomōhala hoʻomōhala?

Hiki ke pale aku nā hunaola maʻi ʻaʻai e ka hoʻololi ʻana i mea ʻole ka hopena o ka lāʻau i hoʻomākaukau ʻia. Inā pēlā, hiki i ka tumo ke loaʻa i kahi ala hou e hoʻokō ai i ka ulu ʻana ʻaʻole i kaukaʻi ʻia. I kekahi mau hanana, ʻoi aku ka maikaʻi o ka hoʻomaʻamaʻa e kau ʻia i ka hoʻohui ʻana i ʻelua mau therapies a i ʻole nā ​​lāʻau chemotherapy maʻamau.

7. He aha nā hopena āpau o ka therapeutical target?

ʻO nā hopena ʻaoʻao maʻamau o nā therapies i hoʻopili ʻia e komo pū me:

• nāwaliwali
• nausea
• ka luaʻi
• pāhoehoe
• ʻeha poʻo
• pilikia
• ka hanu ʻana
• pehu

ʻO nā hopena ʻē aʻe e pili ana i ka depigmentation o ka lauoho, nā pilikia me ke kāpili ʻana o ke koko a me ka hōʻeha ʻana o ka ʻeha, a me ke kiʻekiʻe o ke koko.