Huli ʻulaʻula kou alo ke inu ʻoe? Eia ke kumu

Anter

• ʻO wai ka mea maʻalahi?
• He aha ka hana?
• Weliweli paha?
• Nā hoʻoponopono
• Hiki iaʻu ke pale aku?
• Nā akahele
• Ke laina lalo

ʻAlekohola a me ka holoi ʻana o ka maka

Inā ʻulaʻula kou helehelena ma hope o kekahi mau aniani o ka waina, ʻaʻole ʻoe hoʻokahi. ʻIke ka hapa nui o ka poʻe i ka holoi ʻana i ka helehelena ke inu lākou i ka waiʻona. ʻO ka huaʻōlelo o kēia kūlana he "ʻalekohola flush react."

ʻO ka hapanui o ka manawa, hiki mai ka palaka no ka mea he pilikia ʻoe i ka ʻeli ʻana i ka waiʻona.

ʻO ka poʻe e holoi i ka wā e inu ai lākou he hewa hewa paha ko ka ʻaoʻao aldehyde dehydrogenase 2 (ALDH2). ʻO ALDH2 kahi enzyme i kou kino e kōkua ai e wāwahi i kahi mea i loko o ka waiʻona i kapa ʻia acetaldehyde.

Hiki i ka acetaldehyde nui loa ke kumu i kahi helehelena ʻulaʻula a me nā ʻōuli ʻē aʻe.

E heluhelu e aʻo hou aʻe e pili ana i ke kumu e hana ai ka flushing a me nā mea hiki iā ʻoe ke hana e pili ana.

ʻO wai ka mea maʻalahi?

Manaʻo nā ʻepekema aia ma ka liʻiliʻi he poʻe ma ka honua holoʻokoʻa me ka hemahema ALDH2. Ma kahi o 8 pākēneka o ka heluna kānaka.

ʻO ka poʻe Kepani, Kina, a me nā kūpuna Kōlea e loaʻa ka hopena o ka waiʻona. Ma ka liʻiliʻi, a hiki paha i ka 70 pākēneka, o ka East Asians ʻike i ka holoi ʻana i ka maka e like me ka pane ʻana i ka inu ʻalekohola.

ʻO ka ʻoiaʻiʻo, ke ʻano ʻulaʻula ke ʻano o ka maka ʻulaʻula e kapa ʻia ʻo "ka Asian flush" a i ʻole ka "Asian light."

Ua hōʻike ʻia kekahi mau noiʻi i ka poʻe o ka Iudaio kahi i loaʻa paha kahi mutation ALDH2.

ʻAʻole ʻike ʻia ke kumu e loaʻa ai kēia pilikia i kekahi mau heluna, akā he genetical a hiki ke hoʻoili ʻia e hoʻokahi a ʻelua paha mau mākua.

He aha ka hana?

Hana ʻo ALDH2 maʻamau e wāwahi i ka acetaldehyde. Ke hoʻololi ka hoʻololi genetic i kēia enzyme, ʻaʻole ia e hana i kāna hana.

ʻO ka hemahema ALDH2 ke kumu o ka acetaldehyde hou aʻe e kūkulu i loko o kou kino. Hiki i ka acetaldehyde nui ke hoʻonāukiuki ʻole iā ʻoe i ka ʻalekohola.

ʻO Flushing kekahi hōʻailona, ​​akā ʻo ka poʻe me kēia ʻano e ʻike paha:

• puʻuwai wikiwiki
• ʻeha poʻo
• nausea
• ka luaʻi

Weliweli paha?

ʻOiai ʻaʻole ʻino ka pīpī iā ia iho, he hōʻailona hōʻailona paha ia no nā pilikia ʻē aʻe.

Ua hōʻike ʻia kahi noiʻi ma 2013 e hiki i ka poʻe e pīpī ʻia ma hope o ka inu ʻana ke loaʻa i ka manawa kiʻekiʻe o ka hoʻoulu ʻana i ke koko kiʻekiʻe.

Nānā nā kānaka ʻepekema i nā kāne Kōlea he 1,763 a loaʻa nā "flusher" i inu i nā mea inu ʻehā ma mua o ʻehā mau pule i ka hebedoma iʻoi aku ka nui o ka pilikia o ka hoʻomohala ʻana i ke koko kiʻekiʻe ke hoʻohālikelike ʻia me ka poʻe inu ʻole.

Akā, ʻo ka "non-flushers" wale nō ka nui o ke kahe o ke koko inā ua ʻoi aku lākou ma mua o ʻewalu mau inu i ka pule.

ʻO ka loaʻa o ke koko kiʻekiʻe ke hoʻonui i kou manawa o ka maʻi puʻuwai a me ka hahau.

Ua ʻike ʻia he 10 o nā noiʻi ʻokoʻa e pili ana ka pane ʻana o ka helehelena i ka waiʻona me ka nui o ka maʻi ʻaʻai, ʻo ia hoʻi ka maʻi ʻaʻai esophageal, ma nā kāne ma Asia Hikina. ʻAʻole pili ia i ka maʻi maʻi ʻaʻai ma waena o nā wahine.

Manaʻo kekahi mau kauka he kōkua paha ka hopena flush i ka ʻike ʻana i ka poʻe e makaʻu no kēia mau maʻi.

Nā hoʻoponopono

ʻO nā lāʻau i kapa ʻia ʻo histamine-2 (H2) blockers hiki ke mālama i ka holoi ʻana i nā maka. Hana kēia mau lāʻau i ka hoʻolōʻihi ʻana i ka haki ʻana o ka wai ʻona i acetaldehyde i kou kahe koko. ʻO nā poloka H2 maʻamau ka:

• Pepcid
• Zantac
• Tagamet

ʻO Brimonidine kahi lapaʻau kaulana no ka holoi ʻana i ka maka. ʻO kahi kumuhana kumuhana e hoʻoliʻiliʻi i ka ʻulaʻula o ka helehelena i ka manawa. Hana ka lāʻau ma ka hōʻemi ʻana i ka nui o nā kīʻaha koko liʻiliʻi loa.

Ua ʻae ka US Food and Drug Administration (FDA) i ka brimonidine no ka mālama ʻana i ka rosacea - kahi ʻano ʻili e hana ai i ka ʻulaʻula a me nā puʻupuʻu liʻiliʻi ma ka maka.

ʻO kekahi kalima topical, ʻoxymetazoline, i ʻae ʻia ma 2017 e mālama iā rosacea. Hiki ke kōkua i ka ʻulaʻula o ka helehelena e ka hoʻopili ʻana i nā kīʻaha koko i ka ʻili.

Hoʻohana pū kekahi poʻe i nā kukuna a me nā lāʻau hoʻomālamalama e hōʻemi i ka ʻulaʻula. Hiki i nā mālama ʻana ke kōkua i ka hoʻomaikaʻi ʻana i ke ʻano o nā kīʻaha koko i ʻike ʻia.

He mea nui ia e ʻike i nā hoʻoponopono e kōkua i ka holoi ʻana ʻaʻole e kamaʻilio i ka hemahema ALDH2. Hiki iā lākou ke pale i nā hōʻailona koʻikoʻi i hiki ke hōʻailona i kahi pilikia.

Hiki iaʻu ke pale aku?

ʻO ke ala wale nō e pale ai i ka holoi ʻana o ka maka i ka inu ʻana e pale a pale paha i kāu inu waiʻona. He manaʻo maikaʻi paha kēia, ʻoiai inā ʻaʻohe ou pilikia me ka ʻulaʻula.

Wahi a ka World Health Organization (WHO), ʻo ke ʻona ke kuleana o ka mea i ʻoi aku ma mua o nā make ma ka honua holoʻokoʻa.

Wahi a WHO he "kumu kumu" ka ʻona ma mua o nā ʻeha.

Hiki i ka nui o ka waiʻona ke hoʻonui i kou makaʻu no ka hoʻomohala ʻana i nā pilikia olakino, e like me:

• maʻi maʻi ate
• kekahi maʻi ʻaʻai
• kahe koko kiʻekiʻe
• maʻi puʻuwai a i ʻole hahau
• pilikia pilikia hoʻomanaʻo
• nā pilikia digestive
• kaukaʻi ʻaʻano

Inā inu ʻoe, hoʻāʻo e inu i ke akahai. Hoʻohālikelike ka wehewehe i ka inu "waena" a hoʻokahi inu i ka lā no nā wahine a hiki i ʻelua inu i ka lā no nā kāne.

Nā akahele

ʻO nā lāʻau e hoʻohuli i nā ʻōuli o ka hoʻomanawanui ʻole i ka waiʻona e manaʻo paha ʻoe e hiki ke inu i nā mea hou aʻe ma mua o kāu. Hiki ke weliweli kēia, keu hoʻi inā loaʻa iā ʻoe kahi hemahema ALDH2.

E hoʻomanaʻo, ʻo ka holoi ʻana i ka maka kahi hōʻailona paha e haʻalele ʻoe i ka inu ʻana.

Ke laina lalo

ʻO ka holoi ʻana i ka helehelena ke inu nei ma muli o ka hemahema o ka ALDH2, kahi e hōʻino ai ka inu ʻana i ka waiʻona i kou olakino. ʻO ka poʻe o ka moʻokūʻauhau Asia a me nā Iudaio paha e loaʻa kēia pilikia.

ʻOiai hūnā ʻia ka ʻulaʻula, uhi wale lākou i kāu mau hōʻailona. Inā ʻike ʻoe i ka holoi ʻana i ka maka i ka wā e inu ana, pono ʻoe e hoʻāʻo a palena a hōʻalo paha i ka ʻalekohola.

E kamaʻilio me kāu kauka inā manaʻo ʻoe he hemahema paha kāu ALDH2. Loaʻa nā hoʻāʻo e hōʻoia ua loaʻa iā ʻoe ka ʻāpana i hoʻololi ʻia.