Mea Kākau: Lewis Jackson
Lā O Ka Hana: 14 Mei 2021
HōʻAno Hou I Ka Lā: 17 Nowemapa 2024
Anonim
Proton pump inhibitors (PPI) vs H2 blockers
Wikiō: Proton pump inhibitors (PPI) vs H2 blockers

Anter

ʻO ka mālama ʻana no ka maʻi reflux gastroesophageal (GERD) ma kahi o ʻekolu mau pae. ʻO nā pae mua ʻelua e pili ana i ka lawe ʻana i nā lāʻau a me ka hoʻololi ʻana i ka papaʻai a me ka nohona. ʻO ke kolu o ka pae ka ʻoki kino. Hoʻohana wale ʻia ke ʻoki kino ma ke ʻano he hopena hope loa i nā hihia koʻikoʻi loa o GERD e pili ana i nā pilikia.

E pōmaikaʻi ka hapa nui o nā poʻe i nā hana ma ka hoʻomaʻamaʻa ʻana pehea, ahea, a me nā mea a lākou e ʻai ai. Eia nō naʻe, ʻaʻole maikaʻi ka hoʻoponopono ʻana i ka papaʻai a me ka nohona wale nō no kekahi. I nā hihia theses, hiki i nā kauka ke koi aku i ka hoʻohana ʻana i nā lāʻau e lohi a hooki paha i ka hana ʻana o ka waikawa i loko o ka ʻōpū.

ʻO nā mea kūpale Proton pump (PPIs) kekahi ʻano o ka lāʻau i hiki ke hoʻohana ʻia e hōʻemi i ka waikawa ʻōpū a hoʻomaha i nā hōʻailona GERD. ʻO nā lāʻau ʻē aʻe i hiki ke mālama i ka waikawa ʻōpū nui me nā H2 receptor blockers, e like me famotidine (Pepcid AC) a me cimetidine (Tagamet). Eia nō naʻe, ʻoi aku ka maikaʻi o ka PPI ma mua o ka H2 receptor blockers a hiki ke hoʻomāmā i nā hōʻailona i ka hapanui o ka poʻe i loaʻa ka GERD.

Pehea e hana ai nā Inhibitors Pump Proton?

Hana nā PPI ma ka pale ʻana a hoʻemi ʻana i ka hana o ka waikawa ʻōpū. Hāʻawi kēia i kēlā me kēia manawa i nā manawa o ke kino ʻeha e hoʻōla. Kōkua pū nā PPI i ka pale ʻana i ka puʻuwai puʻuwai, ke ʻano puhi ahi e pili pū me GERD. ʻO nā PPI kekahi o nā lāʻau i ikaika loa no ka hōʻoluʻolu ʻana i nā hōʻailona GERD no ka mea ʻoiai ka liʻiliʻi o ka waikawa hiki ke hana i nā hōʻailona koʻikoʻi.


Kōkua nā PPI i ka hoʻēmi ʻana i ka waikawa ʻōpū ma kahi o ʻehā a 12 mau pule. Hāʻawi kēia nui o ka manawa i ka hoʻōla kūpono o kaʻiʻo esophageal. Lōʻihi paha ka lōʻihi o ka PPI e hōʻoluʻolu ai i kāu mau hōʻailona ma mua o ka H2 receptor blocker, ka mea e hoʻomaka pinepine i ka hoʻoliʻiliʻi acid i loko o hoʻokahi hola. Eia nō naʻe, ʻoi aku ka lōʻihi o ke kōkua hōʻailona mai nā PPI. No laila, kūpono nā lāʻau PPI kūpono loa no ka poʻe me GERD.

Aia kekahi mau ʻano ʻokoʻa o nā Inhibitors Pump Proton?

Loaʻa nā PPI ma kahi kūʻai a ma ke kauka. Aia nā PPI ma luna o ka counter:

  • lansoprazole (Prevacid 24 HR)
  • omeprazole (Prilosec)
  • esomeprazole (Nexium)

Loaʻa ʻo Lansoprazole a me omeprazole e ke kuhikuhi, e like me nā PPI e hiki mai ana.

  • dexlansoprazole (Dexilant, Kapidex)
  • pantoprazole sodium (Protonix)
  • rabeprazole sodium (Aciphex)

Loaʻa kekahi lāʻau lāʻau kuhikuhi e kapa ʻia ʻo Vimovo no ka mālama ʻana iā GERD. Loaʻa iā ia kahi hui o esomeprazole a me naproxen.


Me he mea lā ke hana maikaʻi nei nā PPI kuhikuhi a me nā PPI ma luna o ka counter i ka pale ʻana i nā hōʻailona GERD.

E kamaʻilio me kāu kauka inā ʻaʻole hoʻomaikaʻi ʻo GERD mau hōʻailona me nā PPI over-the-counter a i ʻole reseta i loko o kekahi mau pule. Loaʻa paha iā ʻoe Helicobacter pylori (H. pylori) maʻi kīnā. ʻO kēia ʻano maʻi e pono ai i ka lapaʻau ʻoi aku ka paʻakikī. Eia naʻe, ʻaʻole kumu ka maʻi i nā ʻōuli. Ke hoʻomohala nā ʻōuli, ʻano like lākou me nā hōʻailona GERD. He mea paʻakikī kēia e hoʻokaʻawale i waena o nā ʻano ʻelua. Nā ʻōuli o an H. pylori maʻi pū paha e:

  • nausea
  • kanu pinepine ʻana
  • nalo ʻai ʻole
  • ʻōhūhū

Inā kānalua kāu kauka he loaʻa kāu H. pylori maʻi, e holo lākou i nā hoʻokolohua like ʻole e hōʻoia i ke kuhi. A laila e hoʻoholo lākou i kahi hoʻolālā lapaʻau kūpono.

He aha nā pilikia o ka hoʻohana ʻana i nā Inhibitors Pump Proton?

Ua manaʻo ʻia nā PPI he mea palekana a hoʻomanawanui maikaʻi ʻia nā lāʻau. Eia nō naʻe, ke hōʻike nei ka noiʻi i kēia manawa e pili ana kekahi mau pilikia me ka hoʻohana lōʻihi o kēia mau lāʻau.


Ua ʻike ʻia kahi noiʻi i loaʻa i ka poʻe e hoʻohana ana i nā wā lōʻihi o ka PPI i ka liʻiliʻi o nā ʻano like ʻole i loko o kā lākou bacteria bacteria. Hāʻawi kēia nele o ka like ʻole iā lākou i ka nui o ka makaʻu no nā maʻi, nā haʻihaʻi iwi, a me nā hemahema o ka wikamina a me ka mineral. Aia i loko o kou ʻōpū nā trillion bacteria. ʻOiai kekahi o kēia mau koʻohune he "ʻino," ʻo ka hapa nui o lākou he mea makaʻu ʻole a kōkua i nā mea āpau mai ka digestion a i ka stabilization mood. Hiki paha i nā PPI ke hoʻopilikia i ke kaulike o nā koʻohune i ka manawa, e hoʻoili ana i nā "bacteria" maikaʻi ʻole e kiʻi i nā bacteria maikaʻi. Hiki i kēia ke hopena i ka maʻi.

Hoʻohui ʻia, ua hoʻopuka ka U.S. Food and Drug Administration (FDA) i kahi ma 2011 i ʻōlelo e hoʻohana lōʻihi ʻia nā PPI kuhikuhi e pili ana me nā pae magnesium haʻahaʻa. Hiki i kēia ke hopena i nā pilikia olakino koʻikoʻi, me nā spasms muscle, kuʻi puʻuwai ʻole, a me nā haunaele. Ma kahi o 25 pākēneka o nā hihia a ka FDA i nānā ai, ʻo ka hoʻopili magnesium wale nō ʻaʻole i hoʻomaikaʻi i nā pae magnesium haʻahaʻa. ʻO ka hopena, ua hoʻopau ʻia nā PPI.

Akā ua hoʻokūpaʻa ka FDA aia kahi liʻiliʻi o ka hoʻomohala ʻana i nā pae magnesium haʻahaʻa ke hoʻohana nei i nā PPI over-the-counter e like me ke kuhikuhi. ʻAʻole like me nā PPI i kuhikuhi ʻia, kūʻai ʻia nā mana o ka counter ma nā kaha haʻahaʻa. Hoʻolālā pū ʻia lākou no kahi papa hana ʻelua mau pule ma mua o ʻekolu mau manawa o ka makahiki.

ʻOiai nā hopena ʻē aʻe, he maʻa maikaʻi loa nā PPI no GERD. Hiki iā ʻoe a me kāu kauka ke kūkākūkā i nā pilikia e hiki mai ana a hoʻoholo inā ʻo PPI ke koho maikaʻi loa nāu.

ʻAnuʻu aʻe

Ke hoʻopau ʻoe i ka lawe ʻana i nā PPI, ʻike paha ʻoe i ka hoʻonui ʻana o ka hana acid. Hiki ke hala kēia hoʻonui i mau mahina. Lawe mālie paha kāu kauka iā ʻoe mai kēia mau lāʻau e kōkua i ka pale ʻana i kēia mai ka hanana ʻana. Paipai paha lākou i kēia mau hana i mea e hōʻemi ai i kou hōʻoluʻolu mai nā hōʻailona GERD āpau.

  • ka ʻai ʻana i nā ʻāpana liʻiliʻi
  • ʻai liʻiliʻi momona
  • e hōʻalo nei i ka waiho ʻana ma lalo o ʻelua mau hola ma hope o ka ʻai ʻana
  • e hōʻalo nei i nā meaʻai māmā ma mua o ka hiamoe
  • ʻaʻahu lole ʻaʻano
  • ke hoʻokiʻekiʻe nei i ke poʻo o kahi moe ma kahi o ʻeono iniha
  • ka hōʻalo ʻana i ka ʻalekohola, ka paka, a me nā meaʻai e hoʻomaka ai nā ʻōuli

E hōʻoia e kūkākūkā me kāu kauka ma mua o kou kū ʻana i ka lawe ʻana i nā lāʻau i kuhikuhi ʻia.

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