Pyrimethamine (Daraprim)
Anter
ʻO Daraprim kahi lāʻau lapaʻau antimalarial e hoʻohana ana i ka pyrimethamine ma ke ʻano he mea hana, hiki ke kāohi i ka hana ʻana o nā enzymes e ka protozoan kuleana no ka malaria, a pēlā e mālama ai i ka maʻi.
Hiki ke kūʻai ʻia ʻo Daraprim mai nā hale kūʻai lāʻau lapaʻau maʻamau me kahi kuhikuhi i ke ʻano o nā pahu i loaʻa nā papa he 100 o 25 mg.
Kumukūʻai
ʻO ke kumukūʻai o Daraprim ma kahi o 7 reais, akā hiki ke hoʻololi i ka nui e like me kahi i kūʻai ʻia ai ka lāʻau.
Nā Hōʻike
Hōʻike ʻia ʻo Daraprim no ka pale a me ka mālama ʻana i ka malaria, me nā lāʻau ʻē aʻe. Eia hou, hiki ke hoʻohana ʻia ʻo Daraprim e mālama iā Toxoplasmosis, e like me ka hōʻike a ke kauka.
Pehea e ho ohana
Pehea e hoʻohana ai iā Daraprim ʻokoʻa e like me ke kumu o ka mālama ʻana a me nā makahiki o ka mea hoʻomanawanui, me nā alakaʻi āpau e like me:
Kāohi Malaria
- Nā mākua a me nā keiki ma luna o 10 mau makahiki: 1 papa i kēlā me kēia pule;
- Nā keiki mai 5 a 10 mau makahiki: ½ papa i kēlā me kēia pule;
- Nā keiki ma lalo o 5: ¼ papa o ka pule.
Malaria lapaʻau
- Nā mākua a me nā keiki ma mua o 14 mau makahiki: 2 a 3 mau papa me ka 1000 mg a 1500 mg o ka sulfadiazine i hoʻokahi mahele lāʻau;
- Nā keiki mai 9 a 14 mau makahiki: 2 mau papa me ka 1000 mg o ka sulfadiazine i hoʻokahi mahele lāʻau;
- Nā keiki mai 4 a 8 mau makahiki: 1 papa pū me 1000 mg o ka sulfadiazine i hoʻokahi mahele lāʻau;
- Nā keiki ma lalo o 4 mau makahiki: ʻO ka papa ½ me 1000 mg o ka sulfadiazine i hoʻokahi mahele.
Nā hopena ʻaoʻao
ʻO nā hopena ʻē aʻe o Daraprim e pili ana i nā maʻi ʻili, palpitations, nausea, cramp, diarrhea, ʻai maikaʻi ʻole, ke koko i ka mimi a me nā loli i ka hoʻāʻo ʻana o ke koko.
Nā Kūʻai Kūʻai
Hoʻopiʻi ʻia ʻo Daraprim i nā mea maʻi me ka anemia megaloblastic lua ma muli o ka hemahema o ka folate a i ʻole ka hypersensitivity i ka pyrimethamine a i ʻole kekahi o nā mea o ka haʻilula.
LoaʻA Ka Kaulana
He aha ka ihoiho pepeiao ʻo Hopi a he aha nā makaʻi
