Mea Kākau: Randy Alexander
Lā O Ka Hana: 28 Apelila 2021
HōʻAno Hou I Ka Lā: 17 Nowemapa 2024
Anonim
ʻO nā mea āpau āu e ʻike ai e pili ana i ka nephrotic Syndrome - Ola Kino
ʻO nā mea āpau āu e ʻike ai e pili ana i ka nephrotic Syndrome - Ola Kino

Anter

Hōʻike Overview

Hana ka nephrotic Syndrome i ka hōʻino ʻana o kāu mau puʻupaʻa i ke kumu o kēia mau mea e hoʻokuʻu i nā protein i loko o kāu mimi.

ʻAʻole maʻi ʻo Nephrotic maʻi. ʻO nā maʻi e hōʻino ai i nā kīʻaha koko i kāu mau puʻupaʻa ke kumu o kēia maʻi.

Nā ʻōuli o ka maʻi nephotic

Hōʻike ʻia ka nephrotic Syndrome e kēia:

  • kahi nui o nā protein i loko o ka mimi (proteinuria)
  • kiʻekiʻe kolesterol a me nā pae triglyceride i loko o ke koko (hyperlipidemia)
  • nā pae haʻahaʻa o kahi protein i kapa ʻia ʻo albumin i loko o ke koko (hypoalbuminemia)
  • ʻōhū (edema), keu hoʻi i kou kuʻekuʻe wāwae a me kou mau wāwae, a puni kou mau maka

Ma waho aʻe o nā hōʻailona ma luna aʻe, ʻike paha ka poʻe me nā maʻi nephrotic:

  • mimi hu
  • loaʻa ke kaupaona mai ka hoʻoliʻiliʻi wai i ke kino
  • luhi
  • poho ʻai

Nā kumu nephrotic

Hoʻopiha ʻia kou puʻupaʻa me nā kīʻaha koko liʻiliʻi i kapa ʻia ʻo glomeruli. Ke holo nei kou koko i loko o kēia mau moku, kānana ʻia ka wai hou a me nā huahana ʻōpala i loko o kou mimi. ʻO ka protein a me nā mea ʻē aʻe e pono ai i kou kino e noho i kou kahe koko.


Hana ʻia ka maʻi nephrotic ke hōʻino ʻia ka glomeruli a ʻaʻole hiki ke kānana pono i kou koko. ʻO ka hōʻino i kēia mau kīʻaha koko e ʻae i ka protein i loko o kāu mimi.

ʻO Albumin kekahi o nā protein i nalowale i kāu mimi.Kōkua ʻo Albumin i ka huki hou ʻana i ka wai mai kou kino i loko o kou puʻupaʻa. Lawe ʻia kēia wai i kāu mimi.

Me ka ʻole o ka albumin, paʻa kou kino i ka wai keu. ʻO kēia ke kumu o ka pehu (edema) i kou mau wāwae, wāwae, kuʻekuʻe wāwae, a me kou alo.

Nā kumu kumu o ka maʻi nephrotic

Hoʻopili wale kekahi mau ʻano i nā nephrotic syndrome i nā puʻupaʻa. Kapa ʻia kēia mau kumu ke kumu nui o ka nephrotic syndrome. Loaʻa kēia mau ʻano:

  • Glomerulosclerosis (segmental glomerulosclerosis) (FSGS). ʻO kēia kahi ʻano i ʻulaʻula ʻia ka glomeruli mai ka maʻi, a defect genetic, a i ʻole kumu i ʻike ʻole ʻia.
  • Nephropathy membranous. I kēia maʻi, mānoanoa nā membrane i ka glomeruli. ʻAʻole ʻike ʻia ke kumu o ka mānoanoa, akā hiki pū paha me ka lupus, ka maʻi hepitis B, malaria, a i ʻole ka maʻi ʻaʻai.
  • Maʻi maʻi loli. No kahi kanaka me kēia maʻi, ʻike maʻamau nā kiko o ka puʻupaʻa ma lalo o kahi microscope. Akā no kekahi kumu i ʻike ʻole ʻia, ʻaʻole ia e kānana pono.
  • Trombosis aʻa koko. I kēia maʻi, ālai ke kīpoki koko i kahi aa koko e hoʻokahe i ke koko mai ka puʻupaʻa.

Nā kumu kiʻekiʻe o ka maʻi nephrotic

ʻO nā maʻi ʻē aʻe e kumu i ka maʻi nephrotic e hoʻopili i ke kino holoʻokoʻa. Kapa ʻia kēia mau mea ke kumu ʻelua o nephrotic syndrome. Hiki i nā maʻi ke hoʻopili pū:


  • Diabetes. I kēia maʻi, hiki i ke kō kō ʻole i kaohi ʻia ke hōʻino i nā kīʻaha koko ma kou kino āpau, e like me kāu mau puʻupaʻa.
  • Lupus. ʻO ka Lupus kahi maʻi autoimmune nāna e hoʻoulu i nā ami, nā puʻupaʻa, a me nā lālā ʻē aʻe.
  • ʻO Amyloidosis. Hoʻokumu ʻia kēia maʻi laha ʻole e ke kūkulu ʻia ʻana o ka protein amyloid i kāu mau lālā. Hiki iā Amyloid ke kūkulu i loko o kāu mau puʻupaʻa, e hopena paha i ka hōʻino ʻana o ka hakuʻala.

ʻO kekahi mau lāʻau lapaʻau, e like me nā lāʻau hakakā-maʻi a me nā lāʻau anti-inflammatory nonsteroidal (NSAIDs), ua hoʻopili pū ʻia me ka nephrotic syndrome.

ʻO ka papaʻai Nephrotic Syndrome

He mea nui ka papaʻai no ka mālama ʻana i ka maʻi nephrotic. E palena i ka nui o ka paʻakai āu e ʻai ai e pale i ka pehu ʻana a me ka mālama ʻana i kou kaomi koko. E ʻōlelo paha kāu kauka e inu ʻoe i ka wai liʻiliʻi e hōʻemi ai i ka pehu.

Hiki i ka nephrotic Syndrome ke hoʻonui i kāu mau kolesterol a me nā pae triglyceride, no laila e hoʻāʻo e ʻai i kahi papaʻai i haʻahaʻa i ka momona momona a me ka kolesterol. Hiki i kēia ke kōkua i ka hōʻemi i kou makaʻu i ka ulu ʻana i ka maʻi puʻuwai.


ʻOiai ke kumu o kēia ʻano e nalo ai ka protein i loko o kou mimi, ʻaʻole e koi ʻia ka ʻai ʻana i nā protein keu. Hiki i kahi papaʻai protein kiʻekiʻe ke hana i ka nephrotic syndrome i ʻoi aku ka maikaʻi. E hoʻomau i ka heluhelu ʻana e aʻo hou aʻe e pili ana i nā meaʻai e ʻai ai a hōʻalo ke loaʻa ʻoe i ka maʻi nephrotic.

ʻO ka lāʻau lapaʻau nephrotic

Hiki i kāu kauka ke mālama i ke ʻano o ke nephrotic syndrome, a me nā ʻōuli o kēia maʻi. Hiki ke hoʻohana ʻia i nā ʻano lāʻau like ʻole e hoʻokō i kēia:

  • ʻO nā lāʻau kaomi koko. Hiki i kēia ke kōkua i ka hoʻohaʻahaʻa ʻana i ke kahe o ke koko a hōʻemi i ka nui o nā protein i lilo i ka mimi. Hoʻopili kēia mau lāʻau i nā mea hoʻopilikia angiotensin-hoʻololi i nā enzyme (ACE) a me nā angiotensin II receptor blockers (ARBs).
  • ʻO Diuretics. Hoʻokumu nā diuretics i kāu mau puʻupaʻa e hoʻokuʻu i kahi kahe keu, kahi e hoʻohaʻahaʻa i ka pehu. Hoʻopili kēia mau lāʻau i nā mea e like me furosemide (Lasix) a me spironolactone (Aldactone).
  • Statins. Hoʻoiho kēia mau lāʻau i nā pae kolesterol. ʻO kekahi mau laʻana o nā stains me ka atorvastatin calcium (Lipitor) a me ka lovastatin (Altoprev, Mevacor).
  • ʻ thinʻiliʻili koko. Hoʻoemi kēia mau lāʻau i kou hiki ke komo i kou koko a kuhikuhi ʻia inā ua loaʻa ʻoe i ke koko i loko o kou puʻupaʻa. ʻO nā laʻana me heparin a me warfarin (Coumadin, Jantoven).
  • Nā mea kāohi Immune ʻōnaehana. Kōkua kēia mau lāʻau i ka mālama ʻana i ka ʻōnaehana paleʻāina ma lalo o ka kaohi a hiki ke lilo i mea kōkua no ka mālama ʻana i kahi ʻano kumu e like me ka lupus. ʻO kahi laʻana o kahi lāʻau lapaʻau hoʻopōpō-pale ʻo corticosteroids.

E makemake paha kāu kauka e hana i nā hana e hōʻemi ai i kāu makaʻu o ka maʻi. No ka hana ʻana i kēia, koi paha lākou iā ʻoe e loaʻa i kahi lāʻau lapaʻau pneumococcal a me ka pana o ka maʻi flu makahiki.

ʻO ka maʻi Nephrotic i nā keiki

ʻO lāua ʻelua Hiki ke hana i nā maʻi nephrotic mua a me ka lua i nā keiki. ʻO ka maʻi nephrotic mua ka ʻano maʻamau o nā keiki.

Hiki i kekahi mau keiki ke loaʻa i kekahi mea i kapa ʻia he congenital nephrotic syndrome, e hana ʻia i loko o nā mahina 3 mua o ke ola. Hiki i kēia ke kumu mai i kahi maʻi kīnā hoʻoilina i hoʻoili ʻia a i ʻole kahi maʻi maʻi ma hope koke o ka hānau ʻana. ʻO nā keiki me kēia ʻano e pono paha i kahi transplant kidney.

I nā keiki, nephrotic syndrome ke kumu o kēia mau ʻōuli:

  • ke kuni, ka luhi, ka huhū, a me nā ʻōuli ʻē aʻe o ka maʻi
  • nalo ʻai ʻole
  • koko i ka mimi
  • pāhoehoe
  • kahe koko kiʻekiʻe

ʻO nā keiki me nā maʻi nephrotic Childhood loaʻa nā maʻi ʻoi aku ma mua o ka maʻamau. ʻO kēia no ka mea ʻo nā protein i pale maʻamau iā lākou mai ka maʻi i nalowale i kā lākou mimi. Loaʻa iā lākou he kolesterol koko kiʻekiʻe.

Nā maʻi nephotic

E like me nā keiki, hiki i ka nephrotic syndrome i nā mākua ke loaʻa i nā kumu kumu a me nā lua. I nā mākua, ʻo ke kumu kumu nui maʻamau o nephrotic syndrome ka glomerulosclerosis segmental (FGS).

Pili kēia kulana me kahi kuanauna ʻilihuna. ʻO ka nui o nā protein i loko o ka mimi kahi mea nui i ka hoʻoholo ʻana i ka wānana i kēia mau kānaka. Ma kahi o ka hapalua o ka poʻe me FSGS a me nephrotic syndrome e holomua ana i ka hopena o ka maʻi kidney ma 5 a 10 mau makahiki.

Eia nō naʻe, hana nui nā kumu ʻelua o ka nephrotic syndrome i nā mākua. Ua koho ʻia aia ma kahi o 50 pākēneka o nā hihia nephrotic syndrome i nā mākua i kumu kumu lua e like me ka maʻi diabetes a me ka lupus.

ʻIke diagnose nephrotic

No ke kuhi ʻana i ka maʻi nephrotic, e lawe mua kāu kauka i kāu mōʻaukala olakino. E nīnau ʻia ʻoe e pili ana i kāu mau hōʻailona, ​​nā lāʻau lapaʻau āu e lawe nei, a inā he ʻano olakino kāu.

E hana ana kāu kauka i kahi hoʻokolokolo kino. Hiki i kēia ke komo i nā mea e like me ke ana ʻana i kou kaomi koko a hoʻolohe ʻana i kou puʻuwai.

Hoʻohana ʻia kekahi mau hoʻokolohua e kōkua i ke kuhi hewa ʻana i ka maʻi nephrotic. Pākuʻi ʻia lākou:

  • Nā hoʻāʻo mimi. E noi ʻia ʻoe e hāʻawi i kahi laʻana o ka mimi. Hiki ke hoʻouna ʻia kēia i kahi keʻena hoʻokolohua e hoʻoholo ai inā he nui nā protein i loko o kāu mimi. I kekahi mau hihia, noi ʻia ʻoe e ʻohiʻohi i ka mimi ma kahi o 24 mau hola.
  • Nā hoʻāʻo koko. I kēia mau hoʻāʻo, e lawe ʻia kahi laʻana o ke koko mai kahi aa i kou lima. Hiki ke kālailai ʻia i kēia laʻana e nānā i nā kaha koko o ka hana hakuʻala holoʻokoʻa, nā pae koko o albumin, a me nā pae kolesterol a me nā triglyceride.
  • Kukuna ultrasound. Hoʻohana kahi ultrasound i nā nalu kani e hana i kiʻi o kāu mau puʻupaʻa. Hiki i kāu kauka ke hoʻohana i nā kiʻi i hana ʻia e loiloi i ke ʻano o kāu mau puʻupaʻa.
  • ʻO Biopsy. I ka wā o kahi biopsy, e hōʻiliʻili ʻia kahi mea liʻiliʻi o nā ʻaʻa puʻupaʻa. Hiki ke hoʻouna ʻia kēia i kahi lab no ka hoʻāʻo hou ʻana a hiki ke kōkua i ka hoʻoholo ʻana i ka mea e hoʻopiʻi ai i kou ʻano.

Nā pilikia o ka maʻi nephrotic

ʻO ka lilo o nā protein mai kou koko a me ka hōʻino ʻana i nā puʻupaʻa hiki ke alakaʻi i nā ʻano pilikia like ʻole. ʻO kekahi mau laʻana o nā pilikia kūpono i hiki i kekahi me ka nephrotic syndrome ke ʻike i loko.

  • Huʻi koko. ʻO nā protein e pale i ke kāpili ʻana hiki ke nalowale mai ke koko, e hāpai ana i kou makaʻi i ke koko koko.
  • Kolesterol kiʻekiʻe a me nā triglycerides. Hiki ke hoʻokuʻu ʻia nā kolesterol a me nā triglycerides i loko o kou koko. Hiki i kēia ke hāpai i kāu makaʻu i ka maʻi puʻuwai.
  • Piʻi koko kiʻekiʻe. Hiki i ka hōʻino kīwī ke hoʻonui i ka nui o nā huahana neoneo i kou koko. Hiki i kēia ke hāpai i ke koko.
  • Kaʻai pono ʻole. ʻO ka nalowale o ka protein i ke koko hiki ke alakaʻi i ka pohō kaumaha, i uhi ʻia e ka pehu (edema).
  • Anemia. Loaʻa iā ʻoe ka hemahema o nā hunaola ʻulaʻula e lawe i ka oxygen i nā ʻokena a me nā ʻaʻa o kou kino.
  • Maʻi maʻi ʻōniʻoniʻo. Hiki i kāu mau puʻupaʻa ke lilo i kā lākou hana i ka manawa, e pono ai i ka dialysis a i ʻole ke kuʻi ʻōiwi.
  • Hoka kōwi koʻikoʻi. Hiki i nā hōʻino kīwī ke hoʻonā i kāu mau puʻupaʻa e hoʻopau i ka kānana ʻana o ka ʻōpala, kahi e koi ai i ka hana pōpilikia ma o dialysis.
  • Nā maʻi ʻino. Loaʻa ka nui o ka makaʻu o ka poʻe me nā maʻi nephrotic i ka loaʻa ʻana o nā maʻi, e like me ka pulumonia a me ka meningitis.
  • Kelepona thyroid paʻa ʻole (hypothyroidism). ʻAʻole lawa kāu thyroid i ka nui o ka homone.
  • Maʻi maʻi ʻaʻai Coronary. Pākuʻi ʻia nā kīʻaha koko e kahe ana ke kahe o ke koko i ka puʻuwai.

Nā kumu weliweli o ka maʻi Nephrotic

Aia kekahi mau mea i hiki ke waiho iā ʻoe i kahi makaʻu nui o ka hoʻomohala ʻana i ka maʻi nephrotic. Hiki i kēia mau mea ke:

  • ʻO ke ʻano kumu e hiki ai ke hōʻeha i nā puʻupaʻa. ʻO nā laʻana o ia ʻano ʻano e like me nā mea e like me ka maʻi diabetes, lupus, a i ʻole nā ​​maʻi maʻi ʻōpū ʻē aʻe.
  • Nā maʻi ʻino kikoʻī. Aia kekahi mau maʻi e hoʻonui i kou makaʻu i ka maʻi nephrotic, me HIV, ka maʻi hepitis B a me C, a me ka malaria.
  • Nā Lapaʻau. Hiki i kekahi mau lāʻau lapaʻau hakakā me nā NSAID ke hoʻonui i ka makaʻu o ka maʻi nephrotic.

E hoʻomanaʻo ma muli wale nō o kāu loaʻa ʻana i kekahi o kēia mau kumu pilikia ʻaʻole ia he manaʻo e hoʻomohala ʻoe i ka maʻi nephrotic. Eia nō naʻe, he mea nui e nānā i kou olakino a ʻike i kāu kauka inā ʻike ʻoe i nā ʻōuli e kūlike me ka nephrotic syndrome.

Nānā o ka maʻi nephotic

Hiki ke loli ke kuanaʻike no ka nephrotic syndrome. Aia ia i ka mea e hoʻokumu a me kou olakino holoʻokoʻa.

ʻO kekahi o nā maʻi e kumu i ka nephrotic syndrome e ʻoi aku ka maikaʻi ma kā lākou iho a i ʻole me ka lāʻau. I ka manawa e mālama ʻia ai ka maʻi paʻa, pono e hoʻomaikaʻi i ka maʻi nephrotic.

Eia nō naʻe, hiki i nā kūlana ʻē aʻe ke alakaʻi i ka ʻole kīʻaha, ʻoiai me ka lāʻau. Ke hiki mai kēia, e koi ʻia ka dialysis a maliʻa paha he transplant kidney.

Inā loaʻa iā ʻoe nā ʻōuli e pīhoihoi ana a i ʻole manaʻo ʻoe he maʻi nephrotic paha ʻoe, e hoʻopaʻa i kou manawa me kāu kauka e kūkākūkā i kāu mau hopohopo.

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