Mea Kākau: Eugene Taylor
Lā O Ka Hana: 7 Aukake 2021
HōʻAno Hou I Ka Lā: 16 Nowemapa 2024
Anonim
Megaloblastic Anemia Part 1- Vitamin B12 Deficiency Anemia
Wikiō: Megaloblastic Anemia Part 1- Vitamin B12 Deficiency Anemia

Anter

He aha ka Megemia Megaloblastic?

ʻO ka anemia Megaloblastic kekahi ʻano anemia, kahi maʻi koko ma kahi o ka helu o nā ʻulaʻula i lalo o ka maʻamau. Lawe nā hunaola ʻulaʻula i ka oxygen ma o ke kino. Ke lawa ʻole kou kino i nā hunaola ʻulaʻula, ʻaʻole lawa ka oxygen i kou mau pūnaewele.

Nui a hewahewa nā ʻano anemia me nā kumu a me nā ʻano like ʻole. Kuhi ʻia ka anemia Megaloblastic e nā hunaola ʻulaʻula i ʻoi aku ka nui ma mua o ka maʻamau. ʻAʻole lawa nō hoʻi o lākou. ʻIke ʻia ʻo ka huaʻai B-12 a i ʻole ka anemia deficit folate, a i ʻole ka anemia macrocytic, pū kekahi.

Hoʻokumu ʻia ka anemia Megaloblastic ke hana pono ʻole ʻia nā hunaola ʻulaʻula. Ma muli o ka nui o nā hunaola, ʻaʻole hiki iā lākou ke haʻalele i ka iwi iwi e komo i ke kahe o ke koko a hāʻawi i ka oxygen.

Nā kumu o Megaloblastic Anemia

ʻO nā kumu maʻamau ʻelua o ka megaloblastic anemia ka hemahema o ka wikamina B-12 a i ʻole ka folate. Pono kēia mau meaola ʻelua no ka hana ʻana i nā hunaola ʻulaʻula olakino. Ke lawa ʻole ʻoe o ia mau mea, hoʻopili ia i ka makana o kou mau ʻulaʻula. Ke alakaʻi nei kēia i nā pūnaewele e hoʻokaʻawale ʻole a hana hou i ke ala e pono ai.


Loaʻa ka Vitamin B-12

ʻO ka Vitamin B-12 kahi mea momona i loaʻa i kekahi mau meaʻai e like me kaʻiʻo, iʻa, hua manu, a me ka waiū. ʻAʻole hiki i kekahi poʻe ke omo i ka wikamina B-12 mai kā lākou meaʻai, a hiki i ka megaloblastic anemia. ʻO ka anemia Megaloblastic i hoʻokumu ʻia e ka nele i ka wikamina B-12 i kapa ʻia he anemia ʻinoʻino.

Hoʻokumu pinepine ʻia ka hemahema o ka Vitamin B-12 e ka nele o kahi protein i loko o ka ʻōpū i kapa ʻia ʻo "intrinsic factor." Me ka ʻole o ke kumu intrinsic, ʻaʻole hiki ke omo ʻia ka wikamina B-12, me ka nānā ʻole i ka nui o kāu ʻai. Hiki nō hoʻi ke hoʻomohala i ka anemia anuanu no ka mea ʻaʻole lawa ka wikamina B-12 i kāu papaʻai.

Ka Hakahaka Folate

ʻO Folate kekahi mea waiwai nui i mea nui no ka hoʻomohala ʻana i nā hunaola ʻulaʻula olakino olakino. Loaʻa ʻo Folate i nā meaʻai e like me ka akepaʻa pipi, ka milo, a me nā ʻōpuʻu o Brussels. Hoʻohui pinepine ʻia ʻo Folate me ka waikawa folic - ʻenehana, ʻo ka folic acid kahi ʻano folate o folate, i loaʻa i nā mea hoʻohui. Hiki iā ʻoe ke loaʻa ka waikawa folic i nā cereal paʻa a me nā meaʻai.

ʻO kāu papaʻai kahi mea nui i ka hōʻoia ʻana ua lawa ʻoe i ka folate. Hiki ke kumu ʻia ka hemahema Folate e ka hōʻino ʻana i ka waiʻona mau, ʻoiai ke keʻakeʻa nei ka waiʻona i ka hiki i ke kino ke komo i ka waikawa folic. Loaʻa ka loaʻa ʻole o ka folate i nā wahine hāpai, no ka nui o ka nui o ka folate e pono ai i ka fetus e ulu nei.


He aha nā hōʻailona o ka Megaloblastic Anemia?

ʻO ka hōʻailona maʻamau o ka megaloblastic anemia ka luhi. Hiki ke hoʻololi i nā ʻōuli mai kekahi kanaka a i kekahi kanaka. ʻO nā ʻōuli maʻamau ka:

  • pokole o ka hanu
  • nāwaliwali o nā mākala
  • ʻeleʻele ʻokoʻa o ka ʻili
  • glossitis (swollen alelo)
  • lilo o ka makemake / lilo kaumaha
  • pāhoehoe
  • nausea
  • puʻuwai wikiwiki
  • alelo laumania a palupalu paha
  • ʻūlū nei i nā lima a me nā wāwae
  • ʻōlohelohe i nā hope loa

ʻIke i ka Megaloblastic Anemia

Hoʻokahi hōʻike i hoʻohana ʻia e hōʻoia i nā ʻano anemia he helu piha i ke koko (CBC). Ana kēia hōʻike i nā ʻāpana like ʻole o kou koko. Hiki i kāu kauka ke nānā i ka helu a me ke ʻano o kāu mau hunaola ʻulaʻula. E ʻike ʻia ka nui a me ke kūkulu ʻole inā loaʻa ʻoe me ka anemia megaloblastic. E hōʻiliʻili pū kāu kauka i kāu mōʻaukala olakino a hana i kahi hoʻokolohua kino e kāpae i nā kumu ʻē aʻe o kāu mau hōʻailona.

Pono kāu kauka e hana hou i nā hoʻokolohua koko e ʻike inā ke loaʻa ʻole ka wikamina i kāu anemia. E kōkua pū kēia mau hoʻokolohua iā lākou e ʻike inā he wikamina B-12 a i ʻole ʻo ka folate deficit ke kumu o kēia ʻano.


Hoʻokahi hōʻike i hiki i kāu kauka ke hoʻohana e kōkua i ke kuhi ʻana iā ʻoe ka hōʻike Schilling. ʻO ka hōʻike Schilling kahi hōʻike koko e loiloi i kou hiki ke ʻimi i ka wikamina B-12. Ma hope o kou lawe ʻana i kahi paku o ka radioactive vitamina B-12, e hōʻiliʻili ʻoe i kahi mimi na kāu kauka e kālailai. A laila e lawe ʻoe i ka pākuʻina radioactive like i hui pū ʻia me ka "intrinsic factor" protein e pono ai i kou kino ke komo i ka wikamina B-12. A laila e hāʻawi ʻoe i kahi mimi ʻē aʻe i hiki ai ke hoʻohālikelike ʻia me ka mea mua.

He hōʻailona ia mai hana ʻole ʻoe i kāu kumu ponoʻī inā hōʻike nā mimi i kou lawe wale ʻana i ka B-12 ma hope o ka ʻai ʻana me ka mea kumu. ʻO kēia ka hiki ʻole iā ʻoe ke omo maoli i ka wikamina B-12 kūlohelohe.

Pehea e mālama ʻia ai ka Megaloblastic Anemia?

Pehea ʻoe a me kāu kauka e hoʻoholo ai e mālama i ka anemia megaloblastic ma muli o ke kumu o ia. Hiki i kāu papa hoʻolāʻau ke hilinaʻi i kou makahiki a me kou olakino holoʻokoʻa a me kāu pane i nā mālama ʻana a me ke ʻano o ka maʻi. Hoʻomau pinepine ka mālama ʻana e mālama i ka anemia.

Loaʻa ka Vitamin B-12

I ke kumu o ka anemia megaloblastic i hoʻokumu ʻia e ka hemahema o ka wikamina B-12, pono ʻoe i nā injection o ka huaola B-12 i kēlā me kēia mahina. Hāʻawi ʻia kekahi nā mea kōkua waha. Hiki ke kōkua i ka hoʻohui ʻana i nā meaʻai me ka huaʻai B-12 i kāu papaʻai. ʻO nā meaʻai i loaʻa ka huaʻai B-12 i loko o lākou e komo pū ana:

  • huamoa
  • moa
  • nā cereala paʻa (ʻoiai ʻo bran)
  • ʻiʻo ʻulaʻula (ʻo ka pipi hoʻi)
  • waiū
  • pūpū

Loaʻa i kekahi poʻe i ka hoʻololi kūlohelohe ma ka moʻokūʻauhau MTHFR (methylenetetrahydrofolate reductase). ʻO kēia moʻokūʻauhau MTHFR ke kuleana no ka hoʻolilo ʻana i kekahi mau huaora B, me B-12 a me folate, i loko o kā lākou mau ʻano hiki ke hoʻohana ʻia i loko o ke kino. Kūkā ʻia nā mea me ka hoʻololi MTHFR e lawe i ka methylcobalamin supplement. ʻO ka lawe mau ʻana o ka meaʻai B-12-rich waiwai, nā wikamina, a i ʻole ka paʻa ʻana, ʻaʻole ia e pale aku i ka hemahema a i ʻole nā ​​hopena olakino i kēlā mau mea me kēia hoʻololi kūlohelohe.

Ka Hakahaka Folate

Hiki ke mālama ʻia me ka anemia Megaloblastic i hana ʻia e ka nele o ka folate me nā mea kōkua folic acid a waha a i ʻole intravenous. Hoʻololi pū nā loli meaʻai i nā pae folate. Nā meaʻai e hoʻokomo i kāu papaʻai:

  • ʻalani
  • lau lau ʻōmaʻomaʻo
  • pīnani
  • ʻāpala
  • hua palaoa

E like me ka wikamina B-12, paipai ʻia kēlā me kēia kanaka me ka hoʻololi MTHFR e lawe i ka methylfolate e pale aku ai i ka hemahema folate a me nā pilikia ona.

Noho me Megaloblastic Anemia

I ka wā ma mua, paʻakikī ka mālama ʻana i ka anemia megaloblastic. I kēia lā, hiki i nā poʻe me ka anemia megaloblastic ma muli o ka lawa ʻole o ka wikamina B-12 a i ʻole ka folate hiki ke hoʻokele i kā lākou mau hōʻailona a me ka maikaʻi o ka maikaʻi me ka mālama mau ʻana i nā mea kōkua a me nā mea momona.

Hiki i ka hemahema ʻo Vitamin B-12 ke alakaʻi i nā pilikia ʻē aʻe. Hiki i kēia ke hoʻopili i ka hōʻino nerve, nā pilikia neurological, a me nā pilikia o ka digestive. Hiki ke hoʻohuli i kēia mau pilikia inā ʻike ʻia ʻoe a mālama mua ʻia. Loaʻa ka hoʻāʻo genetic e hoʻoholo inā loaʻa iā ʻoe ka mutation genth MTHFR. ʻO ka poʻe i loaʻa i ka anemia anemia hiki i ka makaʻu kiʻekiʻe loa no ka nāwaliwali o ka iwi iwi a me ka maʻi ʻaʻai ʻōpū. No kēia mau kumu, he mea nui e hopu mua i ka anemia megaloblastic. E kamaʻilio me kāu kauka inā ʻike ʻoe i nā hōʻailona o ka anemia i hiki iā ʻoe a me kāu kauka ke hana me kahi hoʻolālā mālama a kōkua i ka pale ʻana i nā pohō mau.

Nā ʻano anemia like ʻole

Q:

He aha nā ʻokoʻa ma waena o ka anemia macrocytic a me ka anemia microcytic?

Hoʻomanawanui inoa ʻole

A:

ʻO Anemia kahi huaʻōlelo no hemoglobin haʻahaʻa a i ʻole nā ​​ʻulaʻula koko. Hiki ke hoʻokaʻawale ʻia ka anemia i nā ʻano like ʻole e pili ana i ka nui o nā hunaola ʻulaʻula. ʻO ke anemia Macrocytic ka nui o nā hunaola ʻulaʻula ma mua o ka maʻamau. I ka anemia microcytic, ʻoi aku ka liʻiliʻi o nā hunaola ma mua o ka maʻamau. Hoʻohana mākou i kēia hoʻohālikelike no ka mea kōkua ia iā mākou e hoʻoholo i ke kumu o ka anemia.

ʻO nā kumu maʻamau o ka anemia macrocytic ka wikamina B-12 a me ka hemahema folate. ʻO ka anemia Pernicious kahi ʻano o ka anemia macrocytic ma muli o ka hiki ʻole i ke kino ke omo i ka wikamina B-12. ʻOi aku ka maʻalahi o ka poʻe ʻelemākule, nā vegans, a me nā mea ʻona i ka hoʻomōhala ʻana i ka anemia macrocytic.

ʻO ke kumu maʻamau o ka anemia microcytic ka hao-hemahema anemia, maʻamau ma muli o ka maikaʻi ʻole o kaʻai a me ke kahe o ke koko, e like me ka nalowale ʻana o ke koko o menstrual a i ʻole ma o ka gastrointestinal tract. ʻO ka hāpai ʻana, nā wahine menstruating, nā pēpē, a me nā mea me ka papaʻai liʻiliʻi i ka hao e hoʻonui i ka manawa kūpono e hoʻomohala i ka anemia microcytic. ʻO nā kumu ʻē aʻe o ka anemia microcytic e komo pū me nā kīnā i ka hana hemoglobin e like me ka maʻi maʻi sickle, thalassemia, a me sideroblastic anemia.

ʻO Katie Mena, MD ʻO nā pane i pani i nā manaʻo o kā mākou kauka loea. Hoʻomaopopo ʻike ʻike ʻole ʻia nā ʻike āpau a pono ʻole e noʻonoʻo ʻia he ʻōlelo aʻoaʻo olakino.

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