Mea Kākau: Louise Ward
Lā O Ka Hana: 4 Pepeluali 2021
HōʻAno Hou I Ka Lā: 19 Nowemapa 2024
Anonim
Inbrija® (levodopa inhalation powder) Demonstration Video
Wikiō: Inbrija® (levodopa inhalation powder) Demonstration Video

Anter

He aha ʻo Inbrija?

ʻO Inbrija kahi lāʻau lapaʻau inoa inoa inoa inoa i hoʻohana ʻia e mālama ai i ka maʻi o Parkinson. Kauoha ʻia ia no ka poʻe i hoʻi koke i nā hōʻailona o Parkinson ʻoiai ke lawe nei i kahi hui lāʻau i kapa ʻia ʻo carbidopa / levodopa. Ua kapa ʻia kēia hoʻi ʻana o nā ʻōuli he "wā kū." Hana ʻia ia ke pau nā hopena o carbidopa / levodopa a hana ʻole paha ka lāʻau e like me ka mea e pono ai.

Ma hope o kou lawe ʻana iā Inbrija, hiki i kou lolo a lilo i mea i kapa ʻia ʻo dopamine. Kōkua ka Dopamine i nā hōʻailona o ka maʻi o Parkinson.

Hele mai ʻo Inbrija ma ke ʻano he capsule me ka pauka i loko ona. I kēlā me kēia manawa āu e kūʻai ai iā Inbrija, e loaʻa iā ʻoe kahi mea inhaler. Hoʻokomo ʻoe i nā capsule i loko o ka hāmeʻa a huki iā Inbrija ma o kou waha. Loaʻa ka lāʻau i hoʻokahi wale nō ikaika: 42 milligrams (mg) no ka capsule.

Ka hoʻokō ʻana

Ua ʻike ʻia ka maikaʻi o Inbrija i ka mālama ʻana i nā wā o ka maʻi ʻo Parkinson.

Ma kahi hoʻokolohua hoʻokolohua, ua hoʻohālikelike ʻia nā hopena o Inbrija i kahi placebo (kahi lapaʻau me ka ʻole o kahi lāʻau hana) ma 226 poʻe me ka maʻi o Parkinson. ʻO ka poʻe āpau i ke aʻo ʻana e lawe ana i ka carbidopa / levodopa akā ua loaʻa naʻe nā ʻōuli o Parkinson.


Hāʻawi ʻia ʻo Inbrija i ka poʻe i kēlā me kēia manawa i hoʻihoʻi ʻia kahi hōʻailona koke. Ma hope o ka lawe ʻana iā Inbrija, 58% o ka poʻe i hoʻi i ka "ma ka manawa" o ka maʻi o Parkinson. ʻO ka manawa ke ʻike ʻole ʻoe i nā ʻōuli. No nā poʻe i lawe i kahi placebo, 36% i hoʻi i ka wā o Parkinson.

ʻO Generic Inbrija

Loaʻa ʻo Inbrija (levodopa) ma ke ʻano he lāʻau lapaʻau inoa. ʻAʻole i loaʻa i kēia manawa i ka palapala generic.

Nā hopena ʻaoʻao Inbrija

Hiki i Inbrija ke kumu i nā hopena ʻoluʻolu a koʻikoʻi paha. Loaʻa i nā papa inoa aʻe kekahi o nā hopena ʻaoʻao nui i hiki ke hana ʻia i ka wā e lawe ana iā Inbrija. ʻAʻole pili kēia mau papa inoa i nā hopena ʻaoʻao āpau.

No ka ʻike hou aku e pili ana i nā hopena ʻē aʻe o Inbrija, e kamaʻilio me kāu kauka a kauka paha. Hiki iā lākou ke hāʻawi iā ʻoe i nā ʻōlelo aʻoaʻo e pili ana i ka hana me nā hopena ʻē aʻe e hoʻonāukiuki paha.

Nā hopena ʻaoʻao hou aʻe

Hiki i nā hopena ʻaoʻao maʻamau o Inbrija ke hoʻopili pū:

  • ʻūhā
  • maʻi hanu o luna, e like me ke anuanu maʻamau
  • nausea e mau ana i kahi manawa lōʻihi (e nānā i nā "ʻaoʻao hopena kikoʻī" ma lalo)
  • nā wai pouli waihoʻoluʻu pouli e like me ka mimi a i ʻole ka hou (e ʻike i nā kikoʻī o ka ʻaoʻao ʻaoʻao) ma lalo)

E hala paha ka hapa nui o kēia mau hopena i loko o kekahi mau lā a i ʻole ʻelua mau pule. Inā ʻoi aku ke koʻikoʻi a i ʻole hele aku, e kamaʻilio me kāu kauka a kauka paha.


Nā hopena hopena koʻikoʻi

ʻO nā hopena koʻikoʻi koʻikoʻi mai Inbrija ʻaʻole maʻamau, akā hiki iā lākou ke hana. Kāhea koke i kāu kauka inā loaʻa nā hopena koʻikoʻi. Kāhea iā 911 inā manaʻo kou mau hōʻailona i ka hoʻoweliweli ola a i ʻole inā manaʻo ʻoe e loaʻa ana kahi pilikia olakino.

Hiki i nā hopena ʻē aʻe a me kā lākou mau hōʻailona ke hoʻopili:

  • withdrawal syndrome
  • hypotension (haʻahaʻa ke koko,)
  • psychosis a me nā hallucination (ʻike a lohe paha i kahi mea ʻaʻole maoli ma laila)
  • koi ikaika ʻole
  • dyskinesia (kaohi ʻole a neʻe kino ʻole o ke kino)
  • ke hiamoe nei i nā hana maʻamau
  • nā hualoaʻa kūpono ʻole mai nā hoʻokolohua hoʻokolohua, me nā hōʻike ate (hiki i hōʻailona o ka hōʻino o ke ake)

Kaha: E ʻike i ka ʻaoʻao "Nā ʻaoʻao kikoʻī hopena" ma lalo e aʻo hou ai e pili ana i kēlā me kēia hopena.

Nā kikoʻī hopena ʻaoʻao

E noʻonoʻo paha ʻoe i ka pinepine o kekahi mau hopena i hopena ʻia me kēia lāʻau, a i ʻole pili kekahi mau ʻaoʻao iā ia. Eia kekahi mau kikoʻī i nā hopena ʻē aʻe i hiki ʻole i kēia lāʻau ke kumu.


Withdrawal maʻi pale

Hiki paha iā ʻoe ke ʻike i ka haʻalele ʻana i ka maʻi ma hope o ka hoʻohaʻahaʻa ʻana i kāu hana o Inbrija a i ʻole ke oki ʻana i ka lawe ʻana. ʻO kēia no ka maʻa o kou kino i ka loaʻa ʻana o Inbrija. Ke kū koke ʻoe i ka lawe ʻana, ʻaʻohe manawa o kou kino e hoʻoponopono pono ai i ka loaʻa ʻole.

Hiki i nā ʻōuli o ka withdrawal syndrome ke komo pū:

  • wela wela a kuni paha e lōʻihi ana ka lōʻihi
  • huikau
  • ʻoʻoleʻa o ka mākala
  • nā puʻuwai puʻuwai ʻokoʻa (hoʻololi i kāu puʻuwai puʻuwai)
  • loli i ka hanu ʻana

E haʻi i kāu kauka inā ʻike ʻoe i kahi hōʻailona haʻalele. Mai hoʻomaka hou i ka lawe ʻana iā Inbrija inā ʻike ʻoe i nā ʻōuli o ka withdrawal syndrome ke ʻole ke aʻo a kāu kauka iā ʻoe. Kau inoa paha lākou i kekahi mau lāʻau e kōkua ai i kāu mau ʻōuli.

Hypotension (ke koko haʻahaʻa)

Loaʻa paha ʻoe i ke kahe haʻahaʻa i ka lawe ʻana iā Inbrija. I kahi noiʻi hoʻokolohua, 2% o ka poʻe e lawe ana iā Inbrija i loaʻa ke kahe o ke koko haʻahaʻa. ʻAʻohe o ka poʻe i lawe i kahi placebo (kahi lapaʻau me ka ʻole o ka lāʻau hana) i loaʻa ke kahe haʻahaʻa.

I kekahi mau hihia, hiki i ke kaomi haʻahaʻa ke hoʻolilo iā ʻoe i kou kaulike a hāʻule. I mea e hōʻalo ai i kēia, e ala lohi inā ʻoe e noho ana a e moe ana paha i kahi manawa.

Hiki i nā ʻōuli o ke kaomi haʻahaʻa ke komo pū i loko:

  • ʻūpā
  • nausea e lōʻihi ana ka lōʻihi
  • maule ana
  • ʻili clammy

E haʻi i kāu kauka inā ʻike ʻoe i nā hōʻailona o ke kahe o ke koko haʻahaʻa e hele ʻole. Hiki iā lākou ke nānā i kou kaomi koko e ʻike inā loaʻa iā ʻoe kahi kuhiakau. Eia kekahi, kōkua paha lākou iā ʻoe e hana i kahi papaʻai meaʻai a kuhikuhi paha i nā lāʻau e hoʻonui i kou kaomi koko.

Psychosis

Hiki iā ʻoe ke ʻike i nā ʻāpana psychotic (me nā hallucination) ʻoiai e lawe ana iā Inbrija. Me nā māhele psychotic, hiki ke hoʻololi i kou ʻano maoli. ʻIke paha ʻoe, lohe, a manaʻo paha i nā mea ʻaʻole maoli. ʻAʻole maopopo i ke ʻano maʻamau o kēia hopena me Inbrija.

Hiki i nā ʻōuli o ka psychosis ke hoʻopili pū:

  • nā ʻōlelo hoʻohiwahiwa
  • huikau, disorientation, a i ʻole noʻonoʻo pono ʻole
  • hiamoe (pilikia hiamoe)
  • moemoeā nui
  • paranoia (ke manaʻo nei makemake ka poʻe e hōʻeha iā ʻoe)
  • kuhi hewa (manaʻoʻiʻo ʻole i nā mea ʻoiaʻiʻo ʻole)
  • hana hoʻomāinoino
  • hoʻonāukiuki a manaʻo hoʻomaha ʻole paha

Pono e mālama ʻia nā māhele psychotic i mea e hōʻeha ʻole ai iā ʻoe. E hoʻomaopopo koke i kāu kauka inā loaʻa nā hōʻailona o ka psychosis iā ʻoe. Hiki iā lākou ke kuhikuhi i nā lāʻau e kōkua i nā hōʻailona a me nā hanana psychotic. Kāhea iā 911 inā manaʻo kou mau hōʻailona i ka hoʻoweliweli ola a i ʻole inā manaʻo ʻoe e loaʻa ana kahi pilikia olakino.

Koi ikaika ʻole

Hiki i ka Inbrija ke hoʻopili i nā ʻāpana o kou lolo e kaohi i ka mea āu e makemake ai e hana. No laila lawe paha ʻo Inbrija i mea a i kahi manawa āu e makemake ai e hana i nā mea. Eia kekahi, manaʻo paha ʻoe i kahi koi nui e hana i nā mea āu e maʻa mau ʻole ai.

Hiki i nā ʻōuli ke hoʻohui pū:

  • ka makemake koke i ka piliwaiwai
  • hana kūpilikiʻi (e like me ka ʻai ʻana a i ʻole ke kūʻai ʻana)
  • makemake nui i ka hana moekolohe

ʻAʻole maopopo i ke ʻano maʻamau o kēia ʻaoʻao.

I kekahi mau hihia, ʻaʻole hiki i ka poʻe e lawe nei iā Inbrija ke hoʻomaopopo i kā lākou koi pinepine ʻole. E nānā pono inā he hoaaloha a ʻohana paha ʻohana e ʻōlelo ana ʻaʻole ʻoe e hana e like me ʻoe iho. Loaʻa paha iā ʻoe nā koi ikaika ʻole me ka ʻike ʻole iā ia.

E haʻi i kāu kauka inā ʻoe, kou ʻohana, a i ʻole kou mau hoaaloha e ʻike i nā ʻano hana maʻamau ʻole i loko ou. Hiki i kāu kauka ke hōʻemi i kāu lāʻau Inbrija e kōkua i ka hoʻohaʻahaʻa i kou makaʻu i ka loaʻa ʻana o kēia mau koi maʻamau.

ʻO Dyskinesia

Loaʻa paha iā ʻoe ka dyskinesia (kaohi a me ka neʻe ʻana o ke kino) ke lawe nei iā Inbrija. I kahi noiʻi hoʻokolohua, 4% o ka poʻe e lawe ana iā Inbrija i loaʻa i ka diskinesia. I ka hoʻohālikelike ʻana, 1% o ka poʻe e lawe ana i kahi placebo i loaʻa i ka diskinesia. Ua hele kēia mau neʻe i ke alo o ka poʻe, nā ʻōlelo, a me nā ʻāpana ʻē aʻe o ko lākou mau kino.

Hiki i nā ʻōuli o ka dyskinesia ke:

  • hoʻoneʻe i ke poʻo i luna a i lalo
  • ʻalalā
  • hiki ʻole ke hoʻomaha
  • ʻōwili ʻana o ke kino
  • mimilo ʻili
  • ʻōwili ʻana

E hoʻomaopopo i kāu kauka inā loaʻa nā ʻōuli o ka dyskinesia ʻoiai e lawe ana iā Inbrija. E nānā kāu kauka i kāu kūlana kikoʻī e hoʻoholo inā ʻo Inbrija ka lāʻau maikaʻi loa nāu.

E hiamoe ana i nā hana maʻamau

Hiki paha iā Inbrija ke hoʻololi i ka pehea a ke hiamoe ʻoe. Hiki paha iā ʻoe ke ala piha akā hiamoe hiamoe. ʻAʻole maopopo i ke ʻano maʻamau o kēia ʻaoʻao.

ʻOiai e lawe ana iā Inbrija, hiamoe paha ʻoe i ka hana ʻana i nā hana maʻamau, e like me:

  • kalaiwa ʻana
  • hoʻohana a lawelawe ʻana i nā mea weliweli, e like me nā pahi
  • ka ʻai ʻana
  • hana i nā hana kino, e like me ka hāpai ʻana i nā mea kaumaha
  • e kamaʻilio nei i ka poʻe

Hiki weliweli paha ka hiamoe koke ʻana, ke kaukaʻi ʻia i kāu hana. ʻO kahi laʻana, hiki iā ʻoe ke hōʻeha iā ʻoe iho a me nā poʻe ʻē aʻe inā hiamoe ʻoe i ka wā e hoʻokele. No laila, pono ʻoe e hōʻalo i ka hoʻokele a i ʻole ka lawelawe ʻana i nā mea weliweli, e like me nā pahi a i ʻole nā ​​mea kaua ʻē aʻe, ʻoiai e lawe ana iā Inbrija.

E hoʻomaopopo i kāu kauka inā hiamoe koke e hoʻololi i kāu hana o kēlā me kēia lā. E aʻo lākou iā ʻoe pehea e hana pono ai i kēia hopena ʻaoʻao. E kūkākūkā pū lākou inā ʻo Inbrija ka lāʻau kūpono no ʻoe.

Ke hoʻomau nei ka hiamoe ʻana e hoʻomau i ka hana ma mua o hoʻokahi makahiki ma hope o kou hoʻomaka ʻana i Inbrija. Inā kū ʻoe i ka lawe ʻana iā Inbrija, e nīnau i kāu kauka e pili ana i ka hoʻokele, nā mīkini hana a me ka hāpai ʻana i nā mea kaumaha. Hiki iā lākou ke aʻo iā ʻoe inā palekana kēia mau hana iā ʻoe i kēia manawa.

Nā hopena hoʻokolohua maʻamau ʻole

Hoʻokumu paha ʻo Inbrija i nā hopena wahaheʻe i loko o kekahi mau hoʻokolohua keʻena hoʻokolohua, e like me nā hōʻike ate. ʻO kēia mau hopena maikaʻi ʻole he hōʻailona ia o ka hōʻino o ke ake. ʻAʻole maopopo i ke ʻano maʻamau o kēia ʻaoʻao.

Inā manaʻo ʻoe he maikaʻi ʻole kahi hopena hōʻike laboratory (ʻoi aku ke kiʻekiʻe o kahi mea), e nīnau i kāu kauka. Hiki iā lākou ke nānā i kāu mau hopena e nānā inā hewa paha kekahi mea.

Nusea

I kahi noiʻi hoʻokolohua, 5% o ka poʻe i lawe iā Inbrija i loaʻa i ka nausea. I ka hoʻohālikelike, 3% o ka poʻe i lawe i kahi placebo i loaʻa i ka nausea. I nā kūlana ʻelua, ʻaʻole koʻikoʻi ka nausea, a ʻaʻole ia i hoʻokumu i nā pilikia koʻikoʻi.

E kamaʻilio me kāu kauka inā loaʻa ka nausea ma mua o ʻekolu mau lā. Hiki iā lākou ke kōkua iā ʻoe e hana i kahi hoʻolālā meaʻai e kōkua ai i ka hoʻoluhi i kou nausea. Inā kōkua ʻole nā ​​hoʻololi i kāu papaʻai, hiki i kāu kauka ke kuhikuhi i nā lāʻau e hōʻoluʻolu ai i kou nausea.

Mimi kala ʻeleʻele

ʻOiai e lawe ana iā Inbrija, loaʻa paha iā ʻoe ka mimi kala ʻeleʻele. ʻO nā wai ʻē aʻe e like me ka hou, lawaiʻa a phlegm paha e pouli ʻeleʻele pū kekahi. Ma ka laulā, ʻaʻole weliweli kēia a ʻaʻohe hopena maikaʻi ʻole i kou kino.

Inā hoʻomau ʻoe i ka mimi ʻeleʻele a i ʻole nā ​​wai o ke kino a hoʻomaka ʻoe e hopohopo, e kamaʻilio me kāu kauka. Hōʻike paha lākou i nā hoʻokolohua koko e ʻike pono iā Inbrija e palekana iā ʻoe.

Kaumaha (ʻaʻole kahi hopena)

ʻAʻole i hōʻike ʻia ke kaumaha loa ma ke ʻano he hopena ʻaoʻao i kēlā me kēia noiʻi hoʻokolohua ʻana o Inbrija. Eia nō naʻe, ʻo ke kaumaha paha kahi hopena o ka maʻi o Parkinson.

Ua koho ʻia ma kahi o 35% o ka poʻe i loaʻa i ka maʻi ʻo Parkinson e loaʻa paha i nā ʻōuli o ke kaumaha. E loli paha kēia pākēneka ma muli o ka makahiki o ka poʻe. ʻO ka maʻamau, ʻoi aku ka nui o ka makaʻu o ka poʻe ʻōpio me Parkinson.

ʻO nā hōʻailona kaumaha i nā poʻe me ka maʻi ʻo Parkinson he ʻokoʻa ma mua o ka poʻe me ke ʻano ʻole. ʻO nā ʻōuli kaumaha ka mea maʻa mau i ka poʻe me Parkinson e komo pū ana:

  • kaumaha
  • hopohopo nui loa
  • ukiuki
  • dysphoria (manaʻo hauʻoli ʻole loa i ke ola)
  • pessimism (manaʻo e like me nā mea āpau ʻole a ke kali nei paha i nā hopena maikaʻi ʻole)
  • manaʻo o ka pepehi kanaka

E kamaʻilio me kāu kauka inā manaʻo ʻoe ua kaumaha ʻoe. Hiki iā lākou ke hoʻohui iā ʻoe me nā kumuwaiwai a me ke kākoʻo e kōkua iā ʻoe e hōʻoluʻolu maikaʻi. Inā koho lākou iā ʻoe me ke kaumaha, kauoha paha lākou i nā lāʻau e mālama iā ia.

ʻO ka hana Erectile (ʻaʻole kahi hopena)

ʻAʻole i hōʻike ʻia ka hopena o Erectile (ED) ma ke ʻano he hopena ʻaoʻao i kēlā me kēia noiʻi hoʻokolohua ʻana o Inbrija.Akā ʻo nā kāne me ka maʻi ʻo Parkinson e loaʻa iā ED.

Ua koho ʻia he 79% o nā kāne me Parkinson iā ED, nā pilikia ejaculation, a i ʻole ka pilikia e loaʻa ana i kahi orgasm. Inā ʻoi aku ka maikaʻi o ka maʻi o Parkinson kāne, hiki iā ia ke kumu iā ED nui loa.

ʻO nā kāne me ka maʻi ʻo Parkinson i loaʻa ka hopohopo, kaumaha, a i ʻole ke koʻikoʻi paha ua hoʻonui ʻia ʻo ED i ka hoʻohālikelike ʻia me nā poʻe ʻē aʻe. Eia kekahi, ʻo ka inu wai ʻona ʻana a me ka puhipaka ʻana i ka paka hiki ke ʻoi aku ka paʻakikī o ED Pono ʻoe e hōʻalo i ka inu a pume paha inā he ED kāu.

E hoʻomaopopo i kāu kauka inā loaʻa iā ʻoe ʻo ED ʻaʻole e hele. Kauoha paha lākou i nā lāʻau e mālama i kāu ED.

Hoʻoulu (ʻaʻole kahi hopena)

ʻAʻole i hōʻike ʻia ka sweating nui ma ke ʻano he ʻaoʻao i loko o nā noiʻi maʻi o Inbrija. Akā ʻo ka sweating hiki ke lilo i hōʻailona o ke kuhiakau (kaomi haʻahaʻa). ʻO ke kaomi haʻahaʻa haʻahaʻa kahi hopena koʻikoʻi o Inbrija.

ʻO ke kahe haʻahaʻa e pili ana i kāu kaulike a me kāu kūlana i kapa ʻia he orthostatic hypotension. ʻO ka sweating kahi hōʻailona maʻamau o kēia. ʻO nā ʻōuli maʻamau o ka hypotension orthostatic me:

  • ʻūpā
  • nausea
  • maule ana

E hoʻomaopopo i kāu kauka inā ʻike ʻoe i ka sweating nui a i ʻole nā ​​hōʻailona ʻē aʻe o ke kuhiakau orthostatic. E ana lākou i kou kaomi koko e ʻike inā loaʻa iā ʻoe kahi kuhiakau. Inā ʻoe e hana, hiki iā lākou ke kōkua iā ʻoe e hana i kahi hoʻolālā meaʻai e hoʻonui ai i kou kahe koko. Inā ʻaʻole ia e hoʻonui ma o nā loli i kāu papaʻai, hiki i kāu kauka ke kuhikuhi i nā lāʻau e hoʻonui i kou kaomi koko.

Nā huahana Inbrija

ʻO ka lāʻau Inbrija i kuhikuhi ʻia e kāu kauka e kaukaʻi ʻia i ke koʻikoʻi o ke ʻano āu e hoʻohana nei iā Inbrija e mālama ai a me ka hopena o kou kino i ka lāʻau.

ʻO ka maʻamau, e hoʻomaka kāu kauka iā ʻoe ma kahi lāʻau haʻahaʻa. A laila e hoʻoponopono lākou iā ia i ka manawa e hiki ai i ka nui e kūpono iā ʻoe. E kauoha kauka loa i kāu kauka liʻiliʻi e hāʻawi i ka hopena i makemake ʻia.

Hōʻike ka ʻikepili aʻe i nā lāʻau i hoʻohana pinepine ʻia a koi ʻia paha. Eia nō naʻe, e mālama pono i nā lāʻau a ke kauka i kuhikuhi ai nāu. E hoʻoholo kāu kauka i ka mea ʻoi loa e kūpono i kāu mau pono.

Nā ʻano lāʻau a me nā ikaika

Hele mai ʻo Inbrija ma ke ʻano he capsule āu e hanu ai me ka hoʻohana ʻana i kahi inhaler. Loaʻa wale ia i hoʻokahi ikaika: 42 mg i kēlā me kēia capsule.

Nā hana no ka maʻi ʻo Parkinson

ʻO ka hana Inbrija maʻamau he ʻelua mau capsule no kēlā me kēia "wā kau" o ka maʻi o Parkinson. ʻO kahi wā hoʻomaha ke loaʻa ʻoe i nā hōʻailona o Parkinson ʻoiai ʻo kāu lāʻau carbidopa / levodopa.

ʻAʻole pono ʻoe e lawe ma mua o hoʻokahi mahele (ʻelua mau capsule) o Inbrija no kēlā me kēia manawa. Eia kekahi, mai lawe i nā mea ma mua o ʻelima mau helu (10 capsule) o Inbrija i kēlā me kēia lā.

He aha inā e haʻo wau i kahi lāʻau?

E hoʻohana wale ʻia ʻo Inbrija ke loaʻa iā ʻoe kahi wā haʻalele. Inā ʻaʻohe ou wā hoʻomaha, ʻaʻole pono ʻoe e lawe iā Inbrija. Inā he mau nīnau kāu e pili ana i ka wā e lawe ai ʻoe iā Inbrija, e kamaʻilio me kāu kauka.

Pono wau e hoʻohana i kēia lāʻau lōʻihi?

Hoʻohana ʻia ʻo Inbrija ma ke ʻano he lāʻau hoʻomau mau. Inā hoʻoholo ʻoe a me kāu kauka i ka palekana a me ka maikaʻi o Inbrija nāu, lawe paha ʻoe i ka lāʻau lōʻihi.

Inbrija no ka maʻi ʻo Parkinson

Ua ʻae ka Food and Drug Administration (FDA) i nā lāʻau i kuhikuhi ʻia e like me Inbrija e mālama ai i kekahi mau ʻano.

Ua ʻae ʻia ʻo Inbrija e mālama iā "off period" o ka maʻi o Parkinson i ka poʻe e lawe nei i kahi hui lāʻau i kapa ʻia ʻo carbidopa / levodopa.

Hiki ke hala nā manawa o Parkinson ke pau nā hopena o ka carbidopa / levodopa a i ʻole ke holo ʻana o ka lāʻau e like me ka mea e pono ai. Inā kū kēia, loaʻa paha iā ʻoe nā hōʻailona koʻikoʻi o Parkinson, me nā neʻe ʻole i kāohi ʻia. Ma hope o ka pau ʻana o ka wā haʻalele, hoʻomaka paha ʻo carbidopa / levodopa e hana maikaʻi hou nāu.

Ka hoʻokō ʻana

I kahi hoʻokolohua hoʻokolohua, ua maikaʻi ʻo Inbrija i ka mālama ʻana i nā wā o ka maʻi o Parkinson i ka poʻe e lawe ana i ka carbidopa / levodopa. Ua hoʻomaha ʻo Inbrija i nā ʻōuli koʻikoʻi o Parkinson i loaʻa i ka poʻe i kēlā me kēia wā kūleʻa. ʻO ka hapa nui o ka poʻe e lawe ana iā Inbrija ua pau ka manawa o ka manawa ma hope o ka lawe ʻana i ka lāʻau o ka lāʻau.

I loko o kēia noi ʻana, 58% o ka poʻe i ʻehaʻeha nā hōʻailona o ka maʻi o Parkinson a lawe iā Inbrija i hiki ke hoʻi i ko lākou pae "ma" (me ka ʻole o nā ʻōuli o Parkinson). I ka hoʻohālikelike, 36% o ka poʻe i lawe i kahi placebo (kahi lapaʻau me ka ʻole o ka lāʻau hana) hoʻi iā lākou i ka manawa.

I loko o kēia noi ʻana, ua ana ʻia ka pono o Inbrija me ka hoʻohana ʻana i ka pālākiō UPDRS Part III 30 minuke ma hope o ka lawe ʻana i ka lāʻau. ʻO kēia kahi pālākiō e ana i ka nui o nā ʻōuli o ke kanaka o ka maʻi o Parkinson. ʻO ka hōʻemi ʻana o ka helu he mea ʻoi aku ke koʻikoʻi o nā ʻōuli o ke kanaka ma mua.

Ma hope o 12 mau hebedoma, ua hoʻemi ka poʻe i lawe iā Inbrija i ka helu UPRS Māhele III me ka 9.8. Hoʻohālikelike ʻia kēia me ka emi ʻana o ka helu 5.9 no ka poʻe i lawe i kahi placebo.

Inbrija a me ka waiʻona

ʻAʻohe pilina i ʻike ʻia ma waena o Inbrija a me ka wai ʻona. Eia nō naʻe, hiki i ka Inbrija a me ka waiʻona ke hana i ka luʻuluʻu a me ka hiamoe ke hoʻohana ʻia iā lākou iho. Eia kekahi, pilikia paha ʻoe i ka noʻonoʻo ʻana a me ka hoʻohana ʻana i ka noʻonoʻo maikaʻi me kēlā me kēia o lākou. ʻO ka inu ʻana i ka waiʻona i ka wā e lawe ana iā Inbrija hiki ke hōʻeha i kēia mau hopena.

Inā inu ʻoe i ka waiʻona, e kamaʻilio me kāu kauka inā palekana iā ʻoe e inu i ka lawe ʻana iā Inbrija.

Nā hana a Inbrija

Hiki iā Inbrija ke launa pū me nā lāʻau ʻē aʻe. Hiki iā ia ke launa pū me kekahi mau mea hoʻohui.

Hiki i nā launa like ʻole ke kumu i nā hopena like ʻole. ʻO kahi laʻana, hiki i kekahi mau pilina ke keakea me ka maikaʻi o ka hana a Inbrija. Hiki i nā pilina ʻē aʻe ke hoʻonui i kāna hopena a i ʻole e hoʻonui i ke koʻikoʻi.

Inbrija a me nā lāʻau ʻē aʻe

Ma lalo ka papa inoa o nā lāʻau i hiki ke launa pū me Inbrija. ʻAʻohe i loko o kēia papa inoa nā lāʻau āpau i hiki ke launa pū me Inbrija.

Ma mua o ka lawe ʻana iā Inbrija, e kamaʻilio me kāu kauka a me kāu kauka lāʻau. E haʻi iā lākou e pili ana i nā kuhikuhi āpau, nā mea kūʻai aku, a me nā lāʻau ʻē aʻe āu e lawe ai. E haʻi pū iā lākou e pili ana i nā wikamina, nā mea kanu, a me nā mea hoʻopiha āu e hoʻohana ai. Hiki ke kōkua i ka hāʻawi ʻana i kēia ʻike iā ʻoe e hōʻalo i nā launa ʻole.

Inā he mau nīnau kāu e pili ana i nā launa lāʻau e hoʻopili iā ʻoe, e nīnau i kāu kauka a kauka paha.

Inbrija a me kekahi mau lāʻau kaumaha

Monoamine oxidase inhibitors (MAOI) nā lāʻau i hoʻohana ʻia e mālama i ke kaumaha. ʻO ka poʻe e lawe nei i kekahi ʻano o kēia mau lāʻau, i kapa ʻia ʻo nonselective MAOI, ʻaʻole pono lākou e lawe i Inbrija.

Inā ʻoe e lawe i kahi MAOI nonselective, pono ʻoe e kali ma kahi o ʻelua mau pule ma hope o kāu hopena hope ma mua o ka hoʻomaka ʻana iā Inbrija.

Nonselective MAOI i hoʻohana pinepine ʻia no ke kaumaha me:

  • isocarboxazid (Marplan)
  • phenelzine (Nardil)
  • tranylcypromine (Parnate)

E kamaʻilio me kāu kauka inā lawe ʻoe i kahi MAOI nonselective. Hiki iā lākou ke kuhikuhi i kahi koho ʻē aʻe iā Inbrija a i ʻole ka antidepressant e ʻoi aku ka palekana iā ʻoe.

Inā lawe ʻoe i kekahi ʻano MAOI, i kapa ʻia he MAO-B-mea kāohi, hiki iā ʻoe ke lawe iā Inbrija. Eia nō naʻe, ʻo ka lawe pū ʻana i kēia mau lāʻau i hiki ke hāpai i kou makaʻu i ka loaʻa ʻana o ke kuhiakau (kaomi haʻahaʻa). Ma kahi kikoʻī, hoʻonui paha ia i kou manawa o ke kahe ʻana o ke koko haʻahaʻa e pili ana i kou kūlana a me kāu kaulike. Hiki i kēia ke lilo iā ʻoe e lilo i kāu kaulike a hāʻule.

MAO-B-mea kūpale i hoʻohana pinepine ʻia no ke kaumaha me:

  • rasagiline (Azilect)
  • selegiline (Emsam, Zelapar)

E kamaʻilio me kāu kauka inā ʻoe e lawe i kahi mea hōʻoki MAO-B. Hiki iā lākou ke nānā i kou kaomi koko e ʻike inā loaʻa iā ʻoe kahi kuhiakau. Inā pono, hiki iā lākou ke kōkua iā ʻoe e hana i kahi hoʻolālā nutritional a kuhikuhi i ka lāʻau e kāohi i kou kaomi koko.

Kaha: No ka ʻike hou aku e pili ana i ke kaomi haʻahaʻa, e ʻike i ka ʻaoʻao “Inbrija effects” ma luna.

Inbrija a me dopamine D2 mea loaʻa antagonists

Lawe i ka dopamine D2 antagonists o ka receptor me Inbrija i mea e hōʻemi ai ʻo Inbrija. ʻO kēia no ka loaʻa ʻana o nā hopena ʻē aʻe o D2 a me Inbrija i kāu lolo. Hoʻemi ka D2 receptor antagonists i nā pae o ka dopamine i kou lolo, ʻoiai ʻo Inbrija e hoʻonui iā lākou.

Hoʻohana ʻia nā antagonists ʻo D2 e ​​mālama i ka psychosis. ʻO nā dopagon D2 receptor antagonists e komo pū ana:

  • kālaipunahele
  • chlorpromazine
  • haloperidol (Haldol)
  • risperidone (Risperdalone)

ʻO kekahi antagonist D2, metoclopramide (Reglan), hoʻohana ʻia e mālama i ka maʻi reflux gastroesophageal, kahi ʻano mau o ka reflux acid.

E hoʻomaopopo i kāu kauka inā lawe ʻoe i kahi antagonist receptor dopamine D2. Hiki iā lākou ke kamaʻilio pū me ʻoe e pili ana inā hiki iā ʻoe ke lawe iā Inbrija a i ʻole inā ʻoi aku ka maikaʻi o kekahi lāʻau lapaʻau iā ʻoe.

ʻO Inbrija a me isoniazid

ʻO Isoniazid kahi lāʻau antibiotic i hoʻohana ʻia e mālama i ka maʻi kō (TB). ʻO ka hoʻohana ʻana iā Inbrija me isoniazid e hōʻemi paha i ka Inbrija. ʻO kēia no ka hopena o nā lāʻau ʻelua i nā hopena ʻē aʻe i kou lolo. Hoʻemi ʻo Isoniazid i nā pae o ka dopamine i kou lolo, ʻoiai ʻo Inbrija e hoʻonui iā lākou.

E haʻi koke aku i kāu kauka inā kau ʻia ʻo isoniazid e mālama iā TB ʻoiai e lawe ana iā Inbrija. Hiki iā ʻoe ke kamaʻilio e pili ana inā ʻoi aku kahi antibiotic ʻoi aku iā ʻoe. Inā ʻo isoniazid ke koho ʻoi loa, hiki i kāu kauka ke hoʻololi iā ʻoe mai Inbrija i kahi lāʻau ʻokoʻa e mālama i ka maʻi o Parkinson.

Inbrija a me nā paʻakai hao a i ʻole nā ​​huaora

Lawe iā Inbrija me nā lāʻau i loaʻa i nā paʻakai hao a i ʻole nā ​​wikamina e hiki ai ke hōʻemi i ka Inbrija. ʻO kēia no ka mea hiki i nā paʻakai hao a me nā huaora ke hoʻemi i ka nui o Inbrija i hiki i kou lolo.

E hoʻomaopopo i kāu kauka e pili ana i nā lāʻau āpau āu e lawe nei, e like me nā mea ʻoi loa. Hiki iā ʻoe ke kamaʻilio e pili ana inā pono ʻoe e hōʻoki i ka lawe ʻana i nā lāʻau i loaʻa nā paʻakai hao a i ʻole nā ​​huaora i loko o lākou ke lawe nei ʻoe iā Inbrija.

Inbrija a me nā mea kanu a me nā mea hoʻohui

Lawe kekahi poʻe i kahi mea kanu lāʻau i kapa ʻia Mucuna pruriens (Mucuna) e kōkua i ka hōʻoluʻolu i nā hōʻailona o ka maʻi ʻo Parkinson. Hele mai ʻo Mucuna ma ke ʻano he pill a i ʻole he pauka. Loaʻa nā Inbrija a me Mucuna i ka levodopa, a hoʻonui nā mea ʻelua i ka nui o ka dopamine i kou lolo.

Loaʻa ka nui o ka dopamine i kou lolo i hiki ke hōʻeha. Hiki paha ke hopena i nā hopena koʻikoʻi, e like me ke kahe o ke koko, psychosis, a me ka dyskinesia (ʻike i ka ʻāpana "Inbrija effects" ma luna).

E kamaʻilio me kāu kauka inā lawe a makemake paha ʻoe e lawe iā Mucuna i ka hoʻohana ʻana iā Inbrija. Hiki iā ʻoe ke kūkākūkā inā palekana kēia, a inā pēlā, he aha nā ʻōlelo a Mucuna e ʻōlelo ʻia.

Pehea e hana ai ʻo Inbrija

ʻO ka maʻi ʻo Parkinson kahi maʻi neurodegenerative. ʻO kēia ke kumu o ka make ʻana o nā hunaola (i kapa ʻia he neurons) i kou lolo a me ka iwi kuamoʻo. ʻAʻole i ʻike ʻia ke kumu e make ai nā hunaola a no ke aha e ulu ʻole ai nā hunaola hou i ko lākou wahi.

ʻO ka maʻi ʻo Parkinson e lilo ʻoe i mau sel i nā ʻāpana o kou kino e hana i ka dopamine (kahi mea e pono ai ka mālama ʻana i nā neʻe). No laila ke hoʻemi ʻia nei ka dopamine, kahi mea e kōkua ai i ka hoʻomohala ʻana i nā ʻōuli o Parkinson.

Ma ka hala ʻana o ka manawa, hoʻopili ka nalo ʻana o nā pūnaewele i kāu kaohi ma luna o kāu neʻe o kou kino. Ke hiki mai kēia nalowale o ka kaohi, ʻo nā hōʻailona maʻamau o ka maʻi o Parkinson e hoʻomaka pinepine e ʻike (me nā neʻe ʻole i kāohi ʻia).

He aha ka hana a Inbrija?

Hana nui ʻo Inbrija ma ka hoʻonui ʻana i ka nui o ka dopamine i kou lolo.

Kōkua ka nui o ka dopamine i kāu mau keena i koe e hoʻomaikaʻi i kā lākou hana. Kōkua kēia i ka hōʻoluʻolu i nā hōʻailona o ka maʻi o Parkinson a ʻae iā ʻoe e kaohi maikaʻi i kāu neʻe.

Pehea ka lōʻihi o ka hana?

Hoʻomaka ʻo Inbrija e hana i loko o nā minuke ma hope o kou lawe ʻana. No ka hapanui o ka poʻe, hoʻomaha ʻia nā ʻōuli koʻikoʻi o ka maʻi o Parkinson ma waena o 30 mau minuke o ka lawe ʻana iā Inbrija.

Hoʻohana wale ʻia ʻo Inbrija e mālama i nā hōʻailona koʻikoʻi i ka wā "off period" o ka maʻi ʻo Parkinson. E hoʻi paha kāu mau hōʻailona ma hope o ka pau ʻana o nā hopena o Inbrija. I kēia hihia, e lawe hou iā Inbrija e like me ka mea i koi ʻia e kāu kauka (ʻike i ka ʻāpana "Inbrija dosage" ma luna).

E kamaʻilio me kāu kauka inā loaʻa iā ʻoe ma mua o ʻelima mau manawa o ka maʻi ʻo Parkinson i kēlā me kēia lā. Hiki pū, hiki iā ʻoe ke hoʻoholo inā ke holo pono nei kāu lāʻau o Parkinson i kēia lā no ʻoe a i ʻole inā e hoʻāʻo ʻoe i kahi lāʻau ʻokoʻa.

Kumukūʻai Inbrija

E like me nā lāʻau āpau, hiki ke hoʻololi ke kumukūʻai o Inbrija. E ʻike ai i nā kumukūʻai o kēia wā no Inbrija i kou wahi, e nānā iā WellRx.com. ʻO ke kumukūʻai āu e ʻike ai ma WellRx.com ka mea āu e uku ai me ka ʻole o ka ʻinikua. ʻO ke kumukūʻai maoli āu e uku ai ma muli o kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

He mea nui e hoʻomaopopo he hiki wale nō iā Inbrija ma nā hale kūʻai lāʻau lapaʻau kūikawā. ʻO kēia nā hale kūʻai lāʻau i ʻae ʻia e lawe i nā lāʻau lapaʻau kūikawā (nā lāʻau paʻakikī, loaʻa nā kumukūʻai kiʻekiʻe, a i ʻole paʻakikī e lawe).

Kōkua kālā a me nā ʻinikua

Inā makemake ʻoe i kākoʻo kālā e uku no Inbrija, a i ʻole inā pono ʻoe e kōkua i ka hoʻomaopopo ʻana i kāu ʻinikua uhi, loaʻa ke kōkua.

Hāʻawi ʻo Acorda Therapeutics Inc., ka mea hana a Inbrija, i kahi papahana i kapa ʻia Nā lawelawe kākoʻo prescription. Hiki paha i kēia polokalamu ke kōkua i ka hoʻohaʻahaʻa ʻana i ke kumukūʻai o kāu lāʻau. No ka ʻike hou aku a e ʻike inā ua kūpono ʻoe no ke kākoʻo, kāhea iā 888-887-3447 a i ʻole kipa i ka pūnaewele pūnaewele.

Inbrija overdose

ʻO ka hoʻohana ʻana ma mua o ke ana i koi ʻia o Inbrija hiki ke alakaʻi i nā hopena ʻino.

Nā hōʻailona overdose

Hiki i nā ʻōuli o ka overdose ke komo pū me:

  • nā pilikia o ka maʻi puʻuwai, e like me arrhythmia (ka wikiwiki a me ka helu puʻuwai ʻole o ka puʻuwai) a me ka hypension (ke koko kiʻekiʻe)
  • rhabdomyolysis (haki o nā mākala)
  • nā pilikia ʻōpū
  • psychosis (ʻike i ka ʻāpana "Inbrija effects" ma luna)

He aha e hana ai inā he overdose

Inā manaʻo ʻoe ua lawe nui ʻoe i Inbrija, e kāhea i kāu kauka. Hiki iā ʻoe ke kāhea i ka ʻAmelika Hui Pū ʻIa o nā Poison Control ma 800-222-1222 a i ʻole hoʻohana i kā lākou mea hana pūnaewele. Akā inā koʻikoʻi kāu mau ʻōuli, e kāhea iā 911 a i ʻole e hele koke i kahi lumi pilikia kokoke.

Nā koho ʻē aʻe i Inbrija

Loaʻa nā lāʻau ʻē aʻe e mālama i ka maʻi o Parkinson. Ua kūpono paha kekahi no ʻoe ma mua o kekahi.

ʻO nā koho ʻē aʻe i Inbrija e mālama nei i nā "episode" i waho:

  • apomorphine (Apokyn)
  • safinamide (Xadago)

ʻO nā koho ʻē aʻe i Inbrija e mālama ai i ka maʻi o Parkinson e komo pū ana:

  • carbidopa / levodopa (Sinemet, Duopa, Rytary)
  • pramipexole (Mirapex, Mirapex ER)
  • ropinirole (Koi, koi XL)
  • rotigotine (Neupro)
  • selegiline (Zelapar)
  • rasagiline (Azilect)
  • entacapone (Comtan)
  • benztropine (Cogentin)
  • trihexyphenidyl

Inā makemake ʻoe i ka ʻimi ʻana i kahi ʻokoʻa i Inbrija, e kamaʻilio me kāu kauka. Hiki iā lākou ke haʻi iā ʻoe e pili ana i nā lāʻau ʻē aʻe i hana maikaʻi iā ʻoe.

Inbrija vs. Apokyn

Mahalo paha ʻoe pehea e hoʻohālikelike ai ʻo Inbrija i nā lāʻau ʻē aʻe i kuhikuhi ʻia no nā hoʻohana like. Maanei mākou e nānā ai i ka like a like ʻole o Inbrija a me Apokyn.

Hoʻohana

Ua ʻae ka Food and Drug Administration (FDA) iā Inbrija a me Apokyn e mālama i ka poʻe me "nā wā kū" o ka maʻi o Parkinson. Hana ʻia kahi mau manawa ke lawe ka poʻe i ka lāʻau no Parkinson i nā ʻōuli koʻikoʻi o Parkinson.

ʻO ka poʻe e lawe nei i ka carbidopa / levodopa e mālama iā Parkinson e pono iā Inbrija. Hoʻohana ʻia ia e mālama i kekahi hōʻailona o Parkinson.

Hiki paha ke hoʻohana ʻia ʻo Apokyn i ka poʻe e mālama nei i nā lāʻau no Parkinson's. Hoʻohana ʻia ia e mālama i ka neʻe ʻana o ke kino i nā wā i hala o Parkinson.

Aia i loko o Inbrija ka lāʻau levodopa. Apokyn i loko o ka lāʻau apomorphine.

Hoʻonui ka Inbrija a me Apokyn i ka hana dopamine i kou lolo. ʻO kēia ke ʻano o ko lākou hopena i kou kino.

Nā ʻano lāʻau a me ka hoʻoponopono ʻana

Hele mai ʻo Inbrija ma ke ʻano he capsule me ka pauma āu e huki ai. Loaʻa ia i hoʻokahi ikaika: 42 mg. ʻO ka mahele maʻamau o Inbrija ka 84 mg (ʻelua mau capsule) no kēlā me kēia manawa o ka maʻi o Parkinson.

Lawe ʻoe iā Apokyn ma ka hoʻokomo ʻana iā ia ma lalo o kou ʻili (kahi subcutaneous injection). Loaʻa ʻo Apokyn i hoʻokahi ikaika: 30 mg. ʻO ka mahele i koi ʻia ʻo 2 mg a 6 mg i kēlā me kēia wā pau ʻole o Parkinson.

Nā hopena a me nā pilikia

Loaʻa nā Inbrija a me Apokyn i nā hopena ʻaoʻao like a me nā mea ʻokoʻa ʻokoʻa. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻē aʻe i hiki ke hana ʻia me Inbrija, me Apokyn, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

  • Hiki ke hana me Inbrija:
    • ʻūhā
    • maʻi hanu o luna, e like me ke anuanu maʻamau
    • nā wai pouli ʻeleʻele e like me ka mimi a i ʻole ka hou
  • Hiki ke hana me Apokyn:
    • ʻā nui aʻe
    • hiamoe
    • ʻūpā
    • ihu ihope
    • ka luaʻi e lōʻihi ana ka lōʻihi
    • hallucination (ʻike a lohe ʻana paha i kahi mea ʻaʻole maoli ma laila)
    • huikau
    • ka pehu ʻana i kou mau wāwae, nā kuʻekuʻe wāwae, nā wāwae, nā lima, a i ʻole nā ​​ʻāpana ʻē aʻe o kou kino
    • nā hopena pae o ka ʻūpā, e like me ka palapū, pehu, a i ʻole ka ʻūnini
  • Hiki ke hana me nā Inbrija a me Apokyn:
    • nausea e lōʻihi ana ka lōʻihi

Nā hopena hopena koʻikoʻi

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana ʻia me Inbrija, me Apokyn, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

  • Hiki ke hana me Inbrija:
    • nā hualoaʻa kūpono ʻole mai nā hoʻokolohua hoʻokolohua, me nā hōʻike ate (hiki i hōʻailona o ka hōʻino o ke ake)
  • Hiki ke hana me Apokyn:
    • hopena maʻi ʻaʻano
    • huʻi koko
    • hāʻule
    • nā pilikia puʻuwai, me ka puʻuwai puʻuwai
    • manaʻo puʻuwai puʻuwai
    • nā pilikia fibrotic (hoʻololi i kāu mauʻaʻaʻa)
    • priapism (hoʻolōʻihi ʻia, kūkulu ʻeha)
  • Hiki ke hana me nā Inbrija a me Apokyn:
    • psychosis
    • koi ikaika ʻole
    • dyskinesia (kaohi ʻole a neʻe kino ʻole o ke kino)
    • ke hiamoe nei i nā hana maʻamau
    • withdrawal syndrome, me nā ʻōuli e like me ke kuni a me ka puʻuwai puʻuwai
    • hypotension (haʻahaʻa ke koko,)

Ka hoʻokō ʻana

ʻAʻole i hoʻohālikelike pololei ʻia kēia mau lāʻau i nā noiʻi maʻi. Eia nō naʻe, ua ʻike ʻia nā noiʻi i loko o Inbrija a me Apokyn e maikaʻi no ka mālama ʻana i nā wā o ka maʻi ʻo Parkinson.

Nā kumukūʻai

ʻO Inbrija lāua ʻo Apokyn nā lāʻau lapaʻau inoa ʻelua. ʻAʻohe ʻano generic o nā lāʻau āpau i kēia manawa. ʻOi aku ke kumu kūʻai o nā lāʻau lapaʻau inoa inoa ma mua o nā generics.

Wahi a nā koho ma WellRx, ʻo Inbrija lāua ʻo Apokyn ke kumu kūʻai o nā mea like. ʻO ke kumukūʻai āu e uku ai no Inbrija a i ʻole Apokyn e hilinaʻi ia i kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

He mea nui e hoʻomaopopo he hiki wale nō iā Inbrija lāua ʻo Apokyn ma nā hale kūʻai lāʻau lapaʻau kūikawā. ʻO kēia nā hale kūʻai lāʻau i ʻae ʻia e lawe i nā lāʻau lapaʻau kūikawā (nā lāʻau paʻakikī, loaʻa nā kumukūʻai kiʻekiʻe, a i ʻole paʻakikī e lawe).

Pehea e lawe ai iā Inbrija

Hele mai ʻo Inbrija ma ke ʻano he capsule me ka pauma āu e huki ai. Lawe iā Inbrija e like me kāu kauka a kauka paha. Aia kahi pūnaewele hōʻikeʻike a Inbrija i kahi wikiō hōʻikeʻike a me nā kuhikuhi ʻanuʻu e kōkua iā ʻoe e lawe pololei iā Inbrija.

E lawe wale ʻoe iā Inbrija e ka hanu ʻana iā ia. He mea nui ʻaʻole ʻoe e wehe a ale i kekahi capsule Inbrija. E hoʻokomo wale ʻia nā capsule i loko o ka polokalamu inhal Inbrija. E hoʻohana ka hāmeʻa i ka pauka i loko o nā capsule e ʻae iā ʻoe e inhale i ka lāʻau.

Mai hoʻohana i nā capsule Inbrija i loko o nā mea inhaler ʻē aʻe ma mua o ka Inbrija inhaler. Eia kekahi, mai inhale i kekahi lāʻau ʻē aʻe ma o kāu Inbrija inhaler.

E noi i kāu kauka a kauka paha inā pilikia ʻoe i ka lawe ʻana iā Inbrija. E hele wāwae lākou iā ʻoe ma nā ʻanuʻu āpau e ʻike pono ʻoe i ke ala kūpono.

I ka manawa hea e lawe ai

Pono ʻoe e lawe iā Inbrija i ka hoʻomaka o kahi wā i waho o ka maʻi o Parkinson. Eia naʻe, mai lawe i nā ʻoi aku ma mua o ʻelima mau kaha (10 capsule) o Inbrija i hoʻokahi lā. Inā loaʻa iā ʻoe kahi manawa ma hope o ka lawe ʻana i ʻelima mau inbrija o kēlā me kēia lā, e kāhea i kāu kauka. Hiki iā ʻoe ke kūkākūkā inā pono ʻoe i kahi lāʻau ʻokoʻa i kēlā me kēia lā e mālama i ka maʻi o Parkinson no laila ʻaʻole pono ʻoe e hoʻohana pinepine iā Inbrija.

Mai hōʻoki i ka lawe ʻana i kāu lāʻau ʻē aʻe i kēlā me kēia lā e mālama iā Parkinson i ka wā a ma hope paha o ka lawe ʻana iā Inbrija.

Inbrija a hāpai

ʻAʻohe haʻawina hoʻokolohua o Inbrija i nā wahine hāpai. I nā noiʻi holoholona, ​​loaʻa nā hopena maikaʻi ʻole o Inbrija i nā holoholona pēpē. Hānau ʻia nā pēpē me nā kīnā o ka hānau ʻana, me nā pilikia i loko o kā lākou ʻokana a me nā iwi. Eia naʻe, ʻaʻole hōʻike mau ka noiʻi holoholona i nā mea e hana ʻia i nā kānaka.

E kamaʻilio me kāu kauka inā hāpai ʻoe a i ʻole ke hoʻolālā ʻana e hāpai i ka lawe ʻana iā Inbrija. Hiki iā ʻoe ke kūkākūkā i nā pilikia a me nā pono o ka lawe ʻana iā Inbrija.

Inbrija a me ka kaohi hānau

ʻAʻole ʻike ʻia inā palekana ʻo Inbrija e hoʻohana i ka wā hāpai. Inā ʻoe e moekolohe a hiki i kou a i ʻole kāu pakanā ke hāpai, e kamaʻilio me kāu kauka e pili ana i kāu pono hanau hānau ke hoʻohana nei ʻoe iā Inbrija.

Inbrija a me ka waiū hānai

ʻAʻole he mau noiʻi hoʻokolohua e nānā i nā hopena o Inbrija i ka wā o ka hānai ʻana. Akā hōʻike nā hōʻike hoʻokolohua e hele ʻo Inbrija i ka waiū umauma kanaka. Eia kekahi, hōʻike nā noiʻi e hiki i Inbrija ke kumu i kou kino e hana i ka waiū liʻiliʻi. ʻAʻole ʻike ʻia inā pilikia kēia mau pilikia iā ʻoe a i ʻole kāu keiki.

E haʻi i kāu kauka inā ʻoe e hānai ana i ka waiū a hoʻolālā paha i ka hānai ʻana iā ʻoe e lawe ana iā Inbrija. Hiki iā ʻoe ke kamaʻilio e pili ana inā palekana iā ʻoe e lawe iā Inbrija i ka wā e hānai ana i ka waiū.

ʻO nā nīnau maʻamau e pili ana iā Inbrija

Eia nā pane i kekahi o nā nīnau e nīnau pinepine ʻia e pili ana iā Inbrija.

He aha ke ʻano o ka loaʻa ʻana o ka wā 'off' o ka maʻi ʻo Parkinson?

ʻO nā wā kūleʻa o ka maʻi ʻo Parkinson he mau manawa ia e pau ai kāu lāʻau i kēlā me kēia lā e mālama ai i ka maʻi o Parkinson a hana ʻole paha e like me ka mea e pono ai. Ke hiki mai kēia, hoʻi hou nā hōʻailona o kāu Parkinson.

Lawe ka poʻe me ka maʻi ʻo Parkinson i nā lāʻau e hoʻonui i ka nui o ka dopamine i ko lākou lolo. ʻO Dopamine kahi mea e pono ai ke kaohi i nā neʻe o kou kino. Me kaʻole o ka dopamine, hikiʻole i kou kino ke neʻe kūpono. ʻO kēia ke kumu o ka puka ʻana o nā ʻōuli o Parkinson.

ʻO nā lāʻau e hoʻonui i ka nui o ka dopamine i kou lolo e hana maʻamau i nā wā lōʻihi. Akā i kekahi manawa hoʻōki lākou i ka hana iki. I kēia manawa a lākou e hana ʻole ai, loaʻa paha iā ʻoe nā ʻōuli o Parkinson. Kēia mau manawa ke hana ʻole kāu lāʻau lapaʻau e kāhea ʻia nā wā o Parkinson.

Hiki paha iaʻu ke kiʻi iā Inbrija ma kaʻu hale kūʻai lāʻau kūloko?

ʻAʻole paha. Hiki paha iā ʻoe ke kiʻi iā Inbrija ma nā hale kūʻai lāʻau lapaʻau kūikawā, i ʻae ʻia e lawe i nā lāʻau lapaʻau kūikawā. ʻO kēia nā lāʻau lapaʻau paʻakikī, loaʻa nā kumukūʻai kiʻekiʻe, a i ʻole paʻakikī e lawe.

E noi i kāu kauka inā ʻaʻole maopopo iā ʻoe kahi e hiki ai iā ʻoe ke kiʻi iā Inbrija. Hiki iā lākou ke paipai i kahi hale kūʻai lāʻau lapaʻau kūikawā i kou wahi e hāpai iā ia.

E pani ʻo Inbrija i kaʻu mahele maʻamau o carbidopa / levodopa?

ʻAʻole, ʻaʻole ia. Hoʻohana wale ʻia ʻo Inbrija e mālama i nā wā o ka maʻi ʻo Parkinson. ʻAʻole pono e lawe ʻia i kēlā me kēia lā e hoʻololi i kāu hoʻohana o carbidopa / levodopa.

E kamaʻilio me kāu kauka inā he hopohopo kāu e pili ana i ka lawe ʻana i ka carbidopa / levodopa a me Inbrija. Hiki i kāu kauka ke wehewehe i ke koʻikoʻi o nā mālama ʻelua e kaohi piha i kāu mau hōʻailona o ka maʻi ʻo Parkinson.

Pono wau e hāhai i kekahi papaʻai i ka hoʻohana ʻana iā Inbrija?

Hiki paha i kāu kauka ke koi aku iā ʻoe e hāhai i kekahi papaʻai ʻoiai e lawe ana iā Inbrija.

ʻO nā papaʻai i waiwai i nā protein a i ʻole nā ​​wikamina e hoʻemi ai i ka Inbrija ke hoʻopau ʻia i ka manawa like me ka lāʻau. ʻO kēia no ka mea e hōʻemi paha nā protein a me nā wikamina i ka nui o Inbrija i hiki i kou lolo. Pono ʻo Inbrija e kiʻi i kou lolo e hana i kou kino.

Hōʻike paha kāu kauka i nā loli ke lawe ʻoe i kāu lāʻau Inbrija e hōʻalo ai i ka lawe ʻana iā ia a puni ka manawa like āu e ʻai nei i nā meaʻai momona i nā huaora a i ʻole nā ​​protein.

E kamaʻilio me kāu kauka inā he nīnau kāu e pili ana i ka mea āu e ʻai ai. Hāʻawi ʻia iā ʻoe i kahi hoʻolālā meaʻai e ukali iā ʻoe e lawe ana iā Inbrija.

Hiki iaʻu ke ale i ka capsule Inbrija?

ʻAʻole, ʻaʻole hiki iā ʻoe. ʻO ka ale ʻana i kahi capsule Inbrija e hoʻoliʻiliʻi pono paha ia. ʻO kēia no ka mea hiki i Inbrija liʻiliʻi ke hiki i kou lolo.

Pono e hoʻokomo i nā capsule Inbrija i loko o ka mea inhal Inbrija e hele mai me nā capsule. I ka hāmeʻa, hoʻokuʻu nā capsule i kahi pauma āu e hanu ai.

E nīnau i kāu kauka a kauka paha inā he nīnau kāu e pili ana i ka lawe ʻana iā Inbrija. Hiki iā lākou ke wehewehe pehea e hoʻohana ai i ka mea inhaler e hōʻoia i ka lawe pololei ʻana iā Inbrija. Hiki iā ʻoe ke kipa aku i ka pūnaewele o Inbrija e ʻike i kahi wikiō hōʻikeʻike a kiʻi i nā kuhikuhi i kēlā me kēia kaʻina no ka lawe pololei ʻana iā Inbrija.

E loaʻa iaʻu nā hōʻailona haʻalele inā kū koke wau i ka lawe ʻana iā Inbrija?

Malia paha. Hiki paha iā ʻoe ke haʻalele i nā ʻōuli inā hoʻohaʻahaʻa ʻoe i kāu mea o Inbrija a i ʻole hoʻōki i ka lawe ʻana iā ia. ʻO kēia no ka maʻa o kou kino iā Inbrija. Ke kū koke ʻoe i ka lawe ʻana, ʻaʻohe manawa o kou kino e hoʻoponopono pono ai i ka loaʻa ʻole.

ʻO ka haʻalele ʻana i nā ʻōuli āu e ʻike ai me Inbrija pū:

  • wela loa a kū lōʻihi paha
  • huikau
  • nāʻiʻo paʻa
  • nā puʻuwai puʻuwai (hoʻololi i ka puʻuwai)
  • loli i ka hanu ʻana

E haʻi i kāu kauka inā ʻike ʻoe i nā ʻōuli o ka haʻalele ʻana ma hope o kou hoʻohaʻahaʻa ʻana i kāu lāʻau o Inbrija a i ʻole ke oki ʻana i ka lawe ʻana. Kau inoa paha lākou i nā lāʻau e kōkua ai i kāu mau ʻōuli.

Hiki iaʻu ke lawe iā Inbrija inā loaʻa iaʻu kahi maʻi pulmonary obstructive maʻi (COPD) a i ʻole hānō?

ʻAʻole paha. Hoʻokumu paha ʻo Inbrija i nā pilikia me kou hanu ʻana a hiki ke hana i nā hōʻailona o ka maʻi maʻi lōʻihi (lōʻihi) i ʻoi aku ka nui. No laila, ʻaʻole koi ʻia ʻo Inbrija no ka poʻe me ka hānō, COPD, a i ʻole nā ​​maʻi maʻi maʻi mau.

E kamaʻilio me kāu kauka inā loaʻa ʻoe i ka maʻi maʻi mau. Hiki iā lākou ke kōkua iā ʻoe e ʻike i kahi lāʻau e kūpono paha iā ʻoe.

Nā hana aka Inbrija

Ma mua o ka lawe ʻana iā Inbrija, e kamaʻilio me kāu kauka e pili ana i kāu mōʻaukala olakino. ʻAʻole kūpono paha ʻo Inbrija iā ʻoe inā loaʻa iā ʻoe kekahi ʻano olakino. Pākuʻi ʻia kēia mau mea:

  • Psychosis. Hoʻokumu paha ʻo Inbrija i nā ʻōuli o psychosis, i hiki ke hoʻololi ʻia i kou ʻano maoli. ʻIke paha ʻoe, lohe, a manaʻo paha i nā mea ʻaʻole maoli. Ma mua o ka lawe ʻana iā Inbrija, e haʻi i kāu kauka inā loaʻa nā ʻōuli o psychosis i ka wā i hala. Inā loaʻa iā ʻoe, ʻaʻole kūpono ka lawe ʻana iā Inbrija iā ʻoe.
  • Nā pilikia mālama impulse. Hiki i ka Inbrija ke hoʻopili i nā ʻāpana o kou lolo e kaohi i ka mea āu e makemake ai e hana. Hiki iā ʻoe ke makemake hou e hana i nā mea āu e maʻa mau ʻole ai, e like me ka pili kālā a me ke kūʻai ʻana. Hoʻopilikia pū kekahi i nā maʻi o ka impulse i ka poʻe e makemake e hana a i ka wā e makemake ai lākou e hana. No laila e hoʻonui i ka Inbrija i kēia mau koi maʻamau inā loaʻa iā ʻoe kahi mōʻaukala o nā maʻi kaohi impulse.
  • ʻO Dyskinesia. Inā ua loaʻa ʻoe i ka dyskinesia (kaohi ʻole a neʻe wale paha o ke kino) i ka wā i hala, ʻaʻole palekana ʻo Inbrija iā ʻoe. ʻO ka lawe ʻana iā Inbrija e hoʻonui paha i kou makaʻu i ka loaʻa ʻana o ka dyskinesia inā ua loaʻa iā ʻoe ke ʻano ma mua.
  • Glaucoma. Inā loaʻa ʻoe i ka glaucoma (kahi maʻi maka e hoʻopili ai i kāu ʻike), maluhia ʻole ʻo Inbrija iā ʻoe. ʻO kēia no ka mea hiki i Inbrija ke kumu o ka hoʻonui ʻana i ke kaomi intraocular (hoʻonui kaomi i nā maka), e hōʻeha paha i kāu glaucoma. Inā loaʻa iā ʻoe ka glaucoma, e nānā ke kauka i kou kaomi maka ke lawe nei ʻoe iā Inbrija e ʻike inā piʻi ka piʻi. Inā kiʻekiʻe kou maka maka, hiki i kāu kauka ke hoʻopau iā ʻoe i ka lawe ʻana iā Inbrija a hoʻāʻo i kahi lāʻau ʻokoʻa.
  • Nā maʻi maʻi maʻi (wā lōʻihi). ʻAʻole koi ʻia ʻo Inbrija no nā poʻe me ka hānō, nā maʻi pulmonary obstructive maʻi (COPD), a i ʻole nā ​​maʻi maʻi māmā ʻē aʻe. Hoʻokumu paha ʻo Inbrija i nā pilikia me kou hanu ʻana a hiki ke hana i nā hōʻailona o kēia mau maʻi māmā i ʻoi aku ka koʻikoʻi.

Kaha: No ka ʻike hou aku e pili ana i nā hopena maikaʻi ʻole o Inbrija, e ʻike i ka ʻāpana "Inbrija effects" ma luna.

Inbrija pau, mālama, a hoʻolei

Ke kiʻi ʻoe iā Inbrija mai ka hale kūʻai lāʻau, e hoʻohui ka kauka i kahi lā palena pau i ka lepili ma ka pūʻolo. ʻO kēia lā he 1 mau makahiki ia mai ka lā a lākou i hāʻawi ai i ka lāʻau.

Kōkua ka lā palena e hōʻoia i ka maikaʻi o Inbrija i kēia manawa. ʻO ke kūlana o ka Food and Drug Administration (FDA) i kēia manawa e hōʻalo i ka hoʻohana ʻana i nā lāʻau i make. Inā loaʻa iā ʻoe kahi lāʻau i hoʻohana ʻole ʻia i hala i ka lā palena pau, e kamaʻilio me kāu kauka lāʻau e pili ana inā hiki paha iā ʻoe ke hoʻohana.

Waihona

Pehea ka lōʻihi o ka maikaʻi o ka lāʻau e hoʻohana ai hiki ke hilinaʻi i nā kumu he nui, e like me pehea a me kahi e mālama ai i ka lāʻau.

Pono e mālama ʻia nā capsule Inbrija i ka mahana wela (68 a 77 ° F a i ʻole 20 a 25 ° C) i loko o kahi pahu paʻa paʻa paʻa ʻole ʻia. Hiki iā ʻoe ke hoʻonui i ke ana wela i 59 a 86 ° F (15 a 30 ° C) inā huakaʻi ʻoe.

ʻAʻole pono e mālama ʻia nā capsule Inbrija i loko o ka Inbrija inhaler. Hiki i kēia ke hoʻopōkole i ka nui o ka manawa o ka noho maikaʻi ʻana o nā capsule. ʻO nā capsule maikaʻi ʻole e hōʻino paha iā ʻoe.

E hoʻolei i ka mea inhaler ma hope o kou hoʻohana ʻana i nā capsule āpau i loko o ka pahu. E loaʻa iā ʻoe kahi mea hoʻōha hou i kēlā me kēia manawa ke hoʻopiha hou i kāu kuhikuhi Inbrija.

Hoʻolei

Inā ʻaʻole pono ʻoe e lawe hou iā Inbrija a loaʻa nā lāʻau i koe, he mea nui ia e hoʻolei aku me ka palekana. Kōkua kēia i ka pale aku i nā poʻe ʻē aʻe, e like me nā keiki a me nā holoholona, ​​mai ka lawe lāʻau ʻana ʻole. Mālama pū kekahi ia i ka lāʻau mai hōʻino i ke kaiapuni.

Hāʻawi ka pūnaewele FDA i nā ʻōlelo aʻoaʻo e pili ana i ka hoʻolāʻau lāʻau. Hiki iā ʻoe ke nīnau i kāu kauka lāʻau no ka ʻike e pili ana i ka hoʻolilo ʻana i kāu lāʻau.

ʻO ka ʻike ʻoihana no Inbrija

Hāʻawi ʻia ka ʻike aʻe no nā kauka lapaʻau a me nā ʻoihana ola.

Nā Hōʻike

Hōʻike ʻia ʻo Inbrija e mālama i nā "wā kū" o ka maʻi o Parkinson. Ua kaupalena ʻia kona hōʻailona i nā mea maʻi e mālama ʻia me carbidopa / levodopa.

Mekanism o ka hana

ʻO ke ʻano o ka hana a Inbrija e hōʻemi ai i nā ʻōuli o nā wā kau o ka maʻi ʻo Parkinson ʻaʻole i ʻike ʻia.

Aia ʻo Inbrija i ka levodopa, kahi mea mua o ka dopamine. Keʻa nei ʻo Levodopa i ka pale ā-lolo. I ka lolo, hoʻololi ʻia ʻo levodopa i dopamine. ʻO ka Dopamine e hōʻea i ka basal ganglia i manaʻo ʻia e hōʻemi i nā ʻōuli o nā ʻāpana o ka maʻi o Parkinson.

Pharmacokinetics a me ka metabolism

I ke alo o carbidopa, kahi kū hoʻokahi o Inbrija 84 mg hiki i ka piko kiʻekiʻe ma waena o 30 mau minuke ma hope o ka hoʻoponopono ʻana. ʻO ka nui o ka nui o ka hopena ma kahi o 50% o nā papa waha waha koke o levodopa.

ʻO ka bioavailability o Inbrija ma kahi o 70% o nā papa waha waha koke o levodopa. I ka manawa o ka ʻōnaehana, hiki i ka Inbrija 84 mg i ka nui o ka hāʻawi o 168 L.

ʻO ka hapanui o Inbrija e loaʻa i ka metabolism enzymatic. ʻO nā ala metabolic nui e pili ana i ka decarboxylation e dopa decarboxylase a me O-methylation e catechol-O-methyltransferase. I ke alo o carbidopa, kahi hoʻomalu hoʻokahi o Inbrija 84 mg kahi hapa hapalua o nā hola he 2.3.

ʻAʻole hōʻike ʻia nā ʻokoʻa i ka piko kiʻekiʻe (Cmax) a me ka wahi ma lalo o ka piko (AUC) ma waena o nā kāne a me nā wahine e lawe ana iā Inbrija. ʻAʻole ʻike ʻia nā ʻokoʻa ma waena o ka poʻe puhipaka a me ka poʻe puhipaka ʻole.

Nā Kūʻai Kūʻai

Hoʻohālikelike ʻia ka hoʻohana ʻana o Inbrija i nā mea maʻi e lawe ana i nā mea hōʻoki monoamine oxidase (MAOI) nonselective. Hoʻohālikelike pū ʻia ia i nā mea maʻi i lawe i nā MAOI nonselective i loko o ʻelua mau pule.

ʻO ka hui pū ʻana o Inbrija a me nonselective MAOI paha ke kumu o ke koko kiʻekiʻe. Inā hoʻomaka kahi mea maʻi e lawe i kahi MAOI nonselective, pono e hoʻopau ʻia ka mālama ʻana me Inbrija.

Waihona

Pono e noho mau nā capsule Inbrija i kā lākou pūʻolo mua. Pono e mālama ʻia ka pūʻolo a me ka ipu ma 68 a 77 ° F (20 a 25 ° C). Hoʻonui ʻia kēia mahana i 59 a 86 ° F (15 a 30 ° C) ke huakaʻi.

Ke mālama nei i nā capsule Inbrija i loko o ka Inbrija inhaler mea hiki ke hoʻololi i ke kūpaʻa o ka lāʻau. Pono e aʻo ʻia nā mea maʻi e pili ana i ka mālama ʻana i nā capsule i kā lākou pahu maoli.

Hoʻolaha: Ua hana ʻo Nūhou Lapaʻau i kēia mau lā e hōʻoia i ka pololei, ka laulā, a me ka lā hou o nā ʻike āpau. Eia nō naʻe, ʻaʻole pono e hoʻohana i kēia ʻatikala i pani no ka ʻike a me ka mākaukau o kahi loea mālama ola laikini. E nīnau mau ʻoe i kāu kauka a i ʻole ʻoihana olakino ʻē aʻe ma mua o ka lawe ʻana i nā lāʻau. Hiki ke loli i ka ʻike o ka lāʻau i loko a ʻaʻole i manaʻo ʻia e uhi i nā hoʻohana a pau, nā kuhikuhi, ka mālama ʻana, nā ʻōlelo aʻoaʻo, nā launa lāʻau, nā hopena maʻi ʻaʻai, a me nā hopena maikaʻi ʻole. ʻO ka loaʻa ʻole o nā ʻōlelo aʻoaʻo a i ʻole nā ​​ʻike ʻē aʻe no kahi lāʻau i hāʻawi ʻia ʻaʻole ia e hōʻike i ka palekana o ka lāʻau a lāʻau paha i kūpono no nā mea maʻi āpau a i ʻole nā ​​hoʻohana kikoʻī āpau.

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