Immunoglobulin A (IgA): he aha ia a he aha ke ʻano ke kiʻekiʻe ia

Anter

• He aha kā IgA
• He aha ka mea hiki ke kiʻekiʻe IgA
• He aha ka mea hiki ke lilo iā IgA haʻahaʻa?

ʻO Immunoglobulin A, ka mea i ʻike nui ʻia me IgA, kahi protein i loaʻa i nā nui i nā membrane mucous, ʻo ka hapa nui i ka hanu hanu a me ka gastrointestinal mucosa, me ka loaʻa i ka waiū umauma, i hiki ke hoʻoili ʻia i ka pēpē i ka hānai ʻana a me ka hoʻoulu ʻana i ka ulu ʻōnaehana pale ʻino.

ʻO kēia immunoglobulin ka hana nui o ka pale ʻana i ka meaola a, no laila, ke komo i nā haʻahaʻa haʻahaʻa, hiki iā ia ke aloha i ka ulu ʻana o nā maʻi, pono e ʻike ʻia a mālama ʻia e like me ke alakaʻi a ke kauka.

He aha kā IgA

ʻO ka hana nui a IgA ka pale ʻana i ke kino i nā maʻi a hiki ke kiʻi ʻia ma o ka hānai ʻana, kahi i lawe ʻia ai nā immunoglobulins a ka makuahine i ka pēpē. Hiki ke hoʻokaʻawale ʻia kēia protein i ʻelua ʻano e like me kona wahi a me nā ʻano, a he mau hana ʻokoʻa paha ia e koʻikoʻi no ka pale ʻana i ka meaola.

• IgA 1, ka mea i loaʻa nui i ka serum a kuleana no ka pale ʻana i ka pale pale pale, no ka mea hiki ke pale i nā mea make a i ʻole nā ​​mea ʻē aʻe i hana ʻia e ka hoʻouka ʻana i nā microorganism;
• IgA 2, aia i loko o nā membrane mucous a loaʻa i pili i kahi mea huna. Kūpono kēia ʻano IgA i ka hapa nui o nā protein i hana ʻia e nā bacteria i kuleana no ka luku ʻia o nā hunaola o nā meaola, a no laila, kūlike i ka laina mua o ka pale e kūʻē i nā agena infectious e komo i ka meaola ma o nā membrane mucous.

Hiki ke loaʻa ʻo Immunoglobulin A i ka waimaka, ka huha a me ka waiū o ka waiū, a ʻoi aku ka noho ʻana i nā genitourinary, digestive a me nā ʻōnaehana hanu, e pale ana i kēia mau ʻōnaehana i nā maʻi.

E ʻike pū i ka holo ʻana o ka ʻōnaehana pale.

He aha ka mea hiki ke kiʻekiʻe IgA

Hiki ke ulu ka IgA ke hoʻololi ʻia nā membrane mucous, keu hoʻi i ka membrane gastrointestinal a me ka mucous membrane, ʻoiai loaʻa pinepine kēia immunoglobulin ma ia wahi. Pēlā, e hoʻonui ʻia ka nui o ka IgA i ka hihia o ka hanu a me nā maʻi ʻōpū a me ka cirrhosis ate, no ka laʻana, a ʻoi aku ka mea e loli ana i ka hihia o nā maʻi ma ka ʻili a me nā puʻupaʻa.

He mea nui e lawe ʻia nā hoʻokolohua ʻē aʻe e ʻike i ke kumu o ka IgA kiʻekiʻe a, no laila, hiki ke hoʻomaka ʻia ka lapaʻau kūpono loa.

He aha ka mea hiki ke lilo iā IgA haʻahaʻa?

ʻO ka emi o ka nui o ka holo ʻana o IgA he genetical a ʻaʻole ia e alakaʻi i ka hoʻomohala ʻana o nā ʻōuli e pili ana i kēia loli, ke manaʻo ʻia he hemahema ke emi ka nui o kēia immunoglobulin ma mua o 5 mg / dL i loko o ke koko.

Eia nō naʻe, hiki i ka liʻiliʻi o kēia immunoglobulin ke holo nei i ke kino ke makemake i ka hoʻomohala ʻana i nā maʻi, ʻoiai ʻaʻole pale ʻia nā membrane mucous. No laila, ma kahi o ka hoʻemi ʻia ʻana ma muli o nā kumu kūlohelohe, hiki i ka hemahema IgA ke loaʻa i ka hihia o:

• Hoʻololi Immunological;
• Asthma;
• Nā maʻi āpau hanu;
• ʻO Cystic fibrosis;
• Leukemia;
• Pāpā maʻi mau;
• Maʻi maʻi Malabsorption;
• Nā hānau hou me ka rubella;
• ʻO ka poʻe i hana i ka hoʻoneʻe iwi iwi;
• ʻO nā keiki i loaʻa i ka maʻi Epstein-Barr.

ʻO ka maʻamau, ke emi ka IgA, hoʻāʻo ke kino e uku no kēia hoʻoliʻiliʻi ma o ka hoʻonui ʻana i ka hana o IgM a me IgG i mea e hakakā ai i ka maʻi a mālama ʻia ka pale o ke kino. He mea nui ia, i ka hoʻohui ʻana i nā ana IgA, IgM a me IgG, lawe ʻia nā hoʻokolohua kikoʻī e ʻike i ke kumu o ka loli a, no laila, hoʻomaka i ka lāʻau kūpono kūpono. E aʻo hou aʻe e pili ana iā IgM a me IgG.