Hepatosplenomegaly: He aha kāu e ʻike ai
Anter
- Nā kuleana o ke akepaʻa a me ka pelupelu
- Nā ʻōuli
- Nā kumu a me nā kumu pilikia
- Nā maʻi ʻino
- Nā maʻi Hematological
- Nā maʻi Metabolic
- Nā kūlana ʻē aʻe
- I nā keiki
- Kānāwai
- Nā pilikia
- Lapaʻau
- Outlook
- Kāohi
Hōʻike Overview
ʻO Hepatosplenomegaly (HPM) kahi maʻi kahi e pehu ai ke ake a me ka iwi āpau ma mua o kā lākou nui maʻamau, ma muli o kekahi o nā kumu.
ʻO ka inoa o kēia ʻano - hepatosplenomegaly - hele mai nā huaʻōlelo ʻelua e pili ana iā ia:
- hepatomegaly: pehu a hoʻonui ʻana paha o ke ake
- splenomegaly: pehu a hoʻonui ʻana paha o ka palapū
ʻAʻole paʻakikī nā hihia āpau o HPM. E hoʻomaʻemaʻe paha kekahi i kahi mea liʻiliʻi. Eia nō naʻe, hiki i ka HPM ke hōʻike i kahi pilikia koʻikoʻi, e like me ka maʻi mālama lysosomal a i ʻole ke kanesa.
Nā kuleana o ke akepaʻa a me ka pelupelu
Loaʻa i ke akepaʻa nā ʻano hana like ʻole me ke detoxifying i kou koko, synthesizing nā polokina, a me nā hakakā maʻiʻaʻai. He hapa nui kāna i ka hana ʻana i nā amino acid a me nā paʻakai bile.
Pono kou kino i ka hao e hana i nā hunaola ʻulaʻula, a me nā hana o kou ake a mālama i kēlā mea hao. Malia paha ʻo ka mea kaulana loa o nā hana o kou ake ka hana ʻana i nā mea ʻōpala o kou kino, a laila hiki ke excreted.
ʻO ka spleen kekahi o nā lālā o kou kino, ma ka nui, ʻaʻole maopopo iki i ka hapa nui o ka poʻe. He kī nui ko ka palolo i kāu ʻōnaehana pale. Kōkua ia iā ia e ʻike i nā pathogens, ʻo ia nā bacteria, nā mea hoʻomaʻi, a me nā microorganism hiki ke hana i nā maʻi. Hoʻokumu ia i nā mea pale e kaua iā lākou.
Hoʻomaʻemaʻe hoʻi kou kuʻi i ke koko a hana ʻia i ka pulp ʻulaʻula a keʻokeʻo e pono ai e hana a hoʻomaʻemaʻe i nā huna koko. E aʻo hou aʻe e pili ana i ka spleen.
Nā ʻōuli
Hiki i nā poʻe me ka hepatosplenomegaly ke hōʻike aku i hoʻokahi a ʻoi paha o kēia mau hōʻailona aʻe:
- luhi
- ʻeha
Nā hōʻailona ʻē aʻe, ʻoi aku paha ke koʻikoʻi, e hoʻopili pū me:
- ʻeha o ka ʻōpū ma ka ʻaoʻao ʻākau luna
- palupalu ma ka ʻaoʻao ʻākau o ka ʻōpū
- nausea a me ka luaʻi
- pehu o ka ʻōpū
- fiva
- ʻumeʻume mau
- jaundice, hōʻike ʻia e nā maka melemele a me ka ʻili
- mimi ʻeleʻele
- pahu noho pālolo
Nā kumu a me nā kumu pilikia
Hepatomegaly kumumea kumumea nā:
- momona
- ʻalo lama
- maʻi ʻaʻai ate
- maʻi hepa
- diabetes
- kolesterol kiʻekiʻe
Hoʻokumu ʻia ʻo Splenomegaly e ka hepatomegaly ma kahi o 30 pākēneka o ka manawa. Nui a hewahewa nā kumu kūpono o ka maʻi akepaʻa:
Nā maʻi ʻino
- hepatitis viral huʻi
- infectious mononucleosis, i ʻike ʻia he glandular fever a i ʻole ka "maʻi honi" a hoʻokumu ʻia e ka maʻi Epstein-Barr
- cytomegalovirus, kahi ʻano ma ka ʻohana herpes virus
- brucellosis, he mea hoʻomaʻi i hoʻoili ʻia ma o ka meaʻai haumia a i ʻole ke launa ʻana me kahi holoholona i loaʻa i ka maʻi
- malaria, he maʻi maʻi i lawe ʻia i ka makika hiki ke hoʻoweliweli i ke ola
- leishmaniasis, kahi maʻi i hoʻokumu ʻia e ka parasite Leishmania a hohola ma o ka nahu ʻana o kahi lele one
- schistosomiasis, i kumu ʻia e kahi worm parasite e hoʻopili ana i ka mimi urinary a i ʻole nā ʻōpū
- maʻi ahulau septicemic, i kumu ʻia e a ʻO Yersinia pestis maʻi a hiki ke hoʻoweliweli i ke ola
Nā maʻi Hematological
- nā maʻi myeloproliferative, kahi e hana ai ka iwi iwi i nā pūnaewele he nui loa
- leukemia, a i ʻole ka maʻi ʻaʻai o ka iwi iwi
- lymphoma, a i ʻole ke kele o ke koko e pili ana i nā hunaola lymphatic
- ʻo ka maʻi anemia ʻona maʻi, kahi maʻi koko hoʻoilina i loaʻa i nā keiki kahi hiki ʻole i nā huna hemoglobin ke hoʻololi i ka oxygen
- thalassemia, kahi maʻi koko hoʻoilina i hana ʻia ai ka hemoglobin me ka ʻole
- myelofibrosis, kahi maʻi ʻaʻai liʻiliʻi o ka iwi iwi
Nā maʻi Metabolic
- ʻO ka maʻi Niemann-pick, kahi maʻi maʻi metabolic koʻikoʻi e pili ana i ka hōʻiliʻili momona i nā pūnaewele
- ʻO ka maʻi o Gaucher, kahi ʻano genetical e hoʻouluulu ai i ka momona i nā mea like ʻole a me nā hunaola
- ʻO Hurler Syndrome, kahi maʻi kūlohelohe me ka nui o ka make o ka make ma o ka hōʻino ʻana o nā meaola
Nā kūlana ʻē aʻe
- maʻi ʻo ke akepaʻa, me ka hepatitis hana mau
- amyloidosis, kahi laha ʻole, hōʻuluʻulu kūpono ʻole o nā protein i pelu ʻia
- systemic lupus erythematosus, ke ʻano maʻamau o ka lupus maʻi autoimmune
- sarcoidosis, kahi ʻano i ʻike ʻia nā hunaola ʻino i nā mea ʻokoʻa
- trypanosomiasis, kahi maʻi parasite i lawe ʻia ma o ka nahu ʻana o kahi lele lele
- hemahema sulfatase he nui, kahi hemahema enzyme laha ʻole
- osteopetrosis, kahi maʻi kūlohelohe i ʻike ʻole ʻia ka iwi i ʻoi aku ka paʻakikī ma mua o ka maʻamau
I nā keiki
Hiki ke hōʻuluʻulu ʻia nā kumu maʻamau o ka hepatosplenomegaly i nā keiki penei:
- nā keiki hānau: nā maʻi mālama a me ka thalassemia
- nā pēpē: ʻaʻole hiki i ke akepaʻa ke hana i ka glucocerebroside, i hiki ai ke hōʻeha nui i ka ʻōnaehana ʻōiwi waena
- nā keiki nui: malaria, kala azar, fever fever, a me sepsis
Kānāwai
He helu kēia o nā hoʻokolohua a kāu kauka i kauoha ai e kōkua i ka hōʻoia ʻana o ka maʻi hepatosplenomegaly. Eia nā:
- kahi ultrasound, ka mea i ʻōlelo pinepine ʻia ma hope o ka loaʻa ʻana o kahi nui o ka ʻōpū i ka wā o kahi hoʻokolohua kino
- kahi CT scan, hiki ke hōʻike i kahi ake ākea a i ʻole nā ʻāpala a me nā meaola e pili ana
- nā hoʻāʻo ʻana o ke koko, me ka hoʻāʻo ʻana o ka hana ate a me ka hoʻowalewale ʻana i ke koko
- kahi scan MRI e hōʻoia i ka hōʻoia ma hope o ka hoʻokolokolo kino
Nā pilikia
ʻO nā pilikia maʻamau o ka hepatosplenomegaly ʻo:
- kahe ana ke koko
- koko i ka noho
- koko i ka luaʻi
- hoka ʻole o ke ake
- encephalopathy
Lapaʻau
Hiki ke hoʻololi ʻia nā mālama ʻana no ka hepatosplenomegaly mai kekahi kanaka a i kekahi kanaka e like me ke kumu o ke ʻano.
A ʻo kahi hopena, ʻo ka papa hana maikaʻi loa nāu e kamaʻilio me kāu kauka e pili ana i kāu ʻike a me kāu ʻōlelo aʻo o ka lāʻau.
Kuhi paha lākou:
- Ke hoʻololi nei i ka nohona i ke kūkākūkā ʻana me kāu kauka. Pono kāu pahuhopu nui e hōʻoki i ka inu ʻana a i ʻole, e hoʻēmi i kāu inu ʻana i ka waiʻona e like me ka hiki; hoʻoikaika kino e like me ka hiki iā ʻoe; a ʻoluʻolu i ka papaʻai olakino. Eia kekahi ʻōlelo aʻoaʻo no ka pili ʻana me ka papaʻai olakino.
- Hoʻomaha, hydration, a me nā lāʻau. Hiki ke mālama maʻalahi ʻia kekahi mau maʻi ʻoi aku ka liʻiliʻi e alakaʻi i ka hepatosplenomegaly me nā lāʻau kūpono a me ka hoʻomaha ʻana ʻoiai e hōʻoia ana ʻaʻole ʻoe e maloʻo. Inā loaʻa ʻoe i kahi maʻi lele, ʻelua pālua kāu mālama ʻana: ka lāʻau e hōʻoluʻolu ai i nā ʻōuli a me nā lāʻau lapaʻau e hoʻoneʻe i ka microorganism infectious.
- Nā mālama maʻi ʻaʻai. Ke loaʻa ka maʻi kumu i ka maʻi ʻaʻai, pono ʻoe i nā lapaʻau kūpono e komo pū ana me ka chemotherapy, radiotherapy, a me ke kahakaha e wehe ai i ka tumo.
- Ka hoʻoliʻiliʻi ate. Inā koʻikoʻi kou hihia, e like me ka hopena o ka cirrhosis, koi paha ʻoe i kahi neʻe ʻana o ke ake. E aʻo i nā ʻoiaʻiʻo e pili ana i ka lawe ʻana i ke ake.
Outlook
Ma muli o nā kumu he nui, ʻaʻohe hopena hopena o ka hepatosplenomegaly. Pili kāu kūlana i nā ʻano like ʻole, e like me ke kumu, ke koʻikoʻi, a me ka mālama ʻana i loaʻa iā ʻoe.
Hoʻomaopopo a mālama ʻia ka HPM ma mua, ʻoi aku ka maikaʻi. E ʻike i kāu kauka inā ʻike ʻoe i nā ʻōuli maʻamau a kuhi paha ua hewa kekahi.
Kāohi
Ma muli o ka like ʻole o nā kumu o ka hepatosplenomegaly, ʻaʻole hiki ke pale ʻia i nā manawa a pau. Eia nō naʻe, hiki i kahi nohona olakino ke kōkua wale. Hōʻalo i ka wai ʻona, loaʻa ka hoʻoikaika kino nui, a ʻai i ka papaʻai olakino e kōkua i ka hōʻemi ʻana i ka hapa nui o nā kumu pilikia maʻamau.