He aha ka Hemostasis a pehea e hana ai

Anter

• Pehea e hana ai ka hehestasis
• 1. Heherasis kumu
• 2. Hehestasis lua
• 3. ʻO Fibrinolysis
• Pehea e ʻike ai i nā loli i ka hemostasis

Kūlike ʻo Hemostasis i kahi kaʻina hana e hana ʻia i loko o nā kīʻaha koko e mālama i ke kahe o ke koko, me ka ʻole o ke kūkulu ʻia ʻana o nā clots a i ʻole ka hemorrhage.

Hana ʻia, heostasis i loko o ʻekolu mau hanana i kū i kahi ala wikiwiki a hoʻohui ʻia a pili nui i nā platelet a me nā protein i kuleana no ka coagulation a me ka fibrinolysis.

Pehea e hana ai ka hehestasis

Hana ʻia ʻo Hemostasis i loko o ʻekolu mau pae i hilinaʻi ʻia a kū like i ka manawa like.

1. Heherasis kumu

Hoʻomaka ka Hemostasis ke hiki ke hōʻino ʻia ka ipu koko. I ka pane ʻana i ka ʻeha, hana ʻia ka vasoconstriction o ka moku ʻeha i mea e hōʻemi ai i ke kahe o ke koko a pale i ke kahe ʻana a i ʻole thrombosis.

I ka manawa like, hoʻoheheʻe ʻia nā platelet a pili i ka endothelium moku ma o von Willebrand factor. A laila hoʻololi nā platelet i ko lākou ʻano i hiki ai iā lākou ke hoʻokuʻu i kā lākou ʻike i ka plasma, kahi e loaʻa ai ka hana hou ʻana i nā pā i ka pūnaewele o ka liona, a hoʻomaka e pili i kekahi i kekahi, e hana ana i ka plug platelet mua, a he manawa manawa ʻole hopena

E aʻo hou aʻe e pili ana i nā platelet a me kā lākou mau hana.

2. Hehestasis lua

I ka manawa like e like me ka hemostasis mua, hana ʻia ka cascade coagulation, e hoʻoulu i nā protein i kuleana no ka coagulation. Ma ke ʻano he hopena o ka casagade coagulation, nā ʻano fibrin, nona ka hana o ka hoʻoikaika ʻana i ka plug platelet mua, e paʻa pono ai.

ʻO nā kumu coagulation he protein i holo i ke koko i kona ʻano hana ʻole, akā hoʻoheheʻe ʻia e like me nā pono o ka meaola a he pahuhopu nui kā lākou no ka fibrinogen i fibrin, he mea nui ia no ke kaʻina stagnation o ke koko.

3. ʻO Fibrinolysis

ʻO Fibrinolysis ke kolu o ka pae o ka hemostasis a komo i loko o ke kaʻina o ka luku ʻana i ka plug hemostatic e hoʻihoʻi i ke kahe o ke koko maʻamau. Hoʻopili ʻia kēia hana e plasmin, kahi protein i loaʻa mai i ka plasminogen a nona ka hana e hoʻoliʻiliʻi ai ka fibrin.

Pehea e ʻike ai i nā loli i ka hemostasis

Hiki ke ʻike ʻia nā loli i ka hemostasis ma o nā hoʻokolohua koko kikoʻī, e like me:

• Ka wā heʻe (TS): Aia kēia hōʻike i ka nānā ʻana i ka manawa ke loaʻa ka hemostasis a hiki ke hana ʻia ma o kahi puka liʻiliʻi i ka pepeiao, no ka laʻana. Ma o ka hopena o ka manawa kahe o ke kahe, hiki ke loiloi i ka hemostasis mua, ʻo ia hoʻi, inā he kuleana kūpono o nā platelet. ʻOiai ke hoʻāʻo nui e hoʻohana ʻia, hiki i kēia ʻenehana ke hōʻoluʻolu, keu hoʻi i nā keiki, ʻoiai he mea pono e hana i kahi puka liʻiliʻi i ka pepeiao a he haʻahaʻa ka pilina me ke kahe o ke kahe o ke kanaka.
• Hōʻike hōʻuluʻulu platelet: Ma o kēia hoʻokolohua ʻana, hiki ke hōʻoia i ka hiki ke hōʻuluʻulu i ka platelet, a he mea maikaʻi pū kekahi ma ke ʻano o ka loiloi ʻana i ka hemostasis mua. Hōʻike ʻia nā platelet o ke kanaka i nā mea like ʻole i hiki ke hoʻokomo i ka coagulation a hiki ke ʻike ʻia ka hopena i kahi hāmeʻa e ana i ke kēkelē o ka hōʻiliʻili platelet;
• Ka manawa Prothrombin (TP): Loiloi kēia hōʻike i ka hiki i ke koko ke hui pū me ka hoʻonāukiuki ʻana i kekahi o nā ala i ka cascade coagulation, ke ala extrinsic. No laila, nānā ia i ka lōʻihi o ke lawe ʻana i ke koko e hana i ka plug lua hemostatic lua. Hoʻomaopopo i ke ʻano o ka hōʻike Prothrombin Time a pehea e hana ai;
• Hoʻopau i ka Manawa Thromboplastin Partial (APTT): Loiloi pū kēia hōʻike i ka hemostasis lua, eia naʻe ke nānā nei i ka hana o nā mea coagulation i loaʻa i ke ala intrinsic o ka cascade coagulation;
• Nā huahana Fibrinogen: Hana ʻia kēia ho'āʻo me ka pahuhopu o ka hōʻoia inā loaʻa lawa ka nui o fibrinogen i hiki ke hoʻohana ʻia e hana fibrin.

Ma waho aʻe o kēia mau hoʻāʻo, hiki i ke kauka ke koi aku i nā poʻe ʻē aʻe, e like me ke ana ʻana i nā kumu o ka hoʻopili ʻana, no ka laʻana, i hiki ai ke ʻike inā aia kahi hemahema i loko o nā mea e hoʻopili ai i nā hihia i hiki ke hoʻopilikia i ke kaʻina o ka hemostasis.