Mau kaulahao kukui manuahi

Anter

• He aha ka hōʻike kaulahao kaulahao manuahi?
• No ke aha ia e hoʻohana ai?
• No ke aha wau e pono ai i kahi mau kaulahao māmā e hoʻāʻo?
• He aha ka hana i ka wā o ka hoʻāʻo ʻana o nā kaulahao māmā?
• Pono wau e hana i kekahi mea e hoʻomākaukau ai no ka hoʻāʻo?
• Aia kekahi mau pilikia i ka hoʻāʻo ʻana o nā kaulahao māmā?
• He aha ke ʻano o nā hopena?
• Aia kekahi mea ʻē aʻe e pono iaʻu e ʻike e pili ana i kahi hōʻike kaulahao māmā?
• Nā kūmole

He aha ka hōʻike kaulahao kaulahao manuahi?

ʻO nā kaulahao māmā nā protein i hana ʻia e nā hunaola plasma, kahi ʻano o ke keʻokeʻo keʻokeʻo. Hana nā hunaola Plasma i immunoglobulins (antibodies). Kōkua ka Immunoglobulins i ka pale ʻana i ke kino i ka maʻi a me nā maʻi. Hoʻokumu ʻia nā Immunoglobulins ke hoʻopili nā kaulahao māmā me nā kaulahao kaumaha, kekahi ʻano protein. Ke hoʻopili aku nā kaulahao māmā me nā kaulahao kaumaha, ʻike ʻia lākou ma ke ʻano nakinaki ʻia nā kaulahao māmā.

ʻO ka maʻamau, hana nā hunaola plasma i kahi liʻiliʻi o nā kaulahao keu i hoʻopaʻa ʻole ʻia me nā kaulahao kaumaha. Hoʻokuʻu ʻia lākou i ke kahe koko. ʻIke ʻia kēia mau kaulahao i hoʻopili ʻole ʻia manuahi nā kaulahao māmā.

ʻElua ʻano o nā kaulahao māmā: nā kaulahao kukui lambda a me kappa. Hoʻomaopopo kahi kaulahao kaulahao manuahi i ka nui o nā lambda a me nā kaulahao kappa manuahi i ke koko. Inā ʻoi aku ka kiʻekiʻe a i ʻole ka haʻahaʻa o ka nui o nā kaulahao māmā ma mua o ka maʻamau, hiki ke manaʻo ia loaʻa ʻoe i kahi maʻi o nā hunaola plasma. Hoʻopili kēia i nā myeloma maha, kahi maʻi ʻaʻai o nā hunaola plasma, a me ka amyloidosis, kahi ʻano e hoʻopilikia ai i ke kūkulu ʻana o nā protein i loko o nā ʻokana a me nā ʻano like ʻole.

Nā inoa ʻē aʻe: ka lākiō kappa / lambda manuahi, kappa / lambda kukui manuahi manuahi, freelite, kappa a me nā lei kukui free lambda, nā kaulahao kukui ʻole immunoglobulin

No ke aha ia e hoʻohana ai?

Hoʻohana ʻia kahi mau kaulahao māmā e kōkua i ke kuhi ʻana a i ʻole nānā i nā maʻi plasma cell.

No ke aha wau e pono ai i kahi mau kaulahao māmā e hoʻāʻo?

Pono paha ʻoe i kēia hōʻoia inā loaʻa iā ʻoe nā ʻōuli o kahi maʻi hunaola plasma. Kaukaʻi ʻia i ka maʻi plasma loaʻa iā ʻoe a me nā mea ola e hoʻopili ʻia, e hoʻopili pū ʻia kāu mau ʻōuli.

• ʻEha iwi
• Ka luhi
• Pōpō a ʻūlū paha i nā lima a me nā wāwae
• Huʻe ʻ Tonglelo
• Nā kiko poni ma ka ʻili

He aha ka hana i ka wā o ka hoʻāʻo ʻana o nā kaulahao māmā?

E lawe kahi ʻoihana mālama ola i kahi laʻana koko mai kahi aa i kou lima, e hoʻohana ana i kahi nila kuʻikuʻi. Ma hope o ka hoʻokomo ʻia ʻana o ka nila, e hōʻiliʻili ʻia kahi koko liʻiliʻi i loko o kahi pahu hoʻāʻo a ipu paha. Hiki paha iā ʻoe ke ʻoni iki i ka wā e hele ai a kuʻi paha ka nila. Lōʻihi kēia ma mua o ʻelima mau minuke.

Pono wau e hana i kekahi mea e hoʻomākaukau ai no ka hoʻāʻo?

ʻAʻole pono ʻoe i kahi hoʻomākaukau kūikawā no ka hoʻāʻo ʻana i nā kaulahao māmā.

Aia kekahi mau pilikia i ka hoʻāʻo ʻana o nā kaulahao māmā?

ʻAʻohe liʻiliʻi loa i ka hōʻoia ʻana o ke koko. Loaʻa paha iā ʻoe ka ʻeha a ʻeha paha ma kahi o ka nila i hoʻokomo ʻia ai, akā ʻo ka hapa nui o nā ʻōuli e hele wikiwiki aku.

He aha ke ʻano o nā hopena?

E hōʻike ana kāu mau hualoaʻa i nā huina no nā kaulahao kukui ʻole nā ​​lambda a me kappa. E hāʻawi pū ia i kahi hoʻohālikelike ma waena o nā mea ʻelua. Inā ʻaʻole maʻamau kāu mau hualoaʻa, manaʻo paha ia he maʻi plasma cell kou, e like me:

• Myeloma lehulehu
• ʻO Amyloidosis
• ʻO MGUS (monoclonal gammopathy o ka ʻike ʻike ʻole ʻia). He kūlana kēia i loaʻa ai iā ʻoe nā pae protein. ʻAʻole kumu pinepine ia i nā pilikia a me nā hōʻailona, ​​akā i kekahi manawa ulu i loko o ka myeloma maha.
• Waldenstrom macroglobulinemia (WM), kahi maʻi ʻaʻai o nā aʻa koko keʻokeʻo. ʻO kahi ʻano o ka lymphoma non-Hodgkin.

E aʻo hou aʻe e pili ana i nā hoʻokolohua hoʻokolohua, nā pae kuhikuhi, a me ka hoʻomaopopo ʻana i nā hopena.

Aia kekahi mea ʻē aʻe e pono iaʻu e ʻike e pili ana i kahi hōʻike kaulahao māmā?

Kauoha pinepine ʻia nā kaulahao kaulahao manuahi me nā hoʻokolohua ʻē aʻe, e like me ka hoʻokolohua ʻana i ke koko immunzineation, e kōkua ai e hōʻoia a hōʻalo paha i kahi kuhi.

Nā kūmole

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5. Nā Hoʻokolohua Lab ma ka Pūnaewele [Pūnaewele]. Wakinekona D.C .: ʻAmelika Hui Pū ʻIa no ka Chemical Clinical; c2001–2019. Nā kaulahao kukui kūʻokoʻa Serum; [hōʻano hou ʻia 2019 Oct 24; haʻi ʻia 2019 Dec 21]; [ma kahi o 2 pale]. Loaʻa mai: https://labtestsonline.org/tests/serum-free-light-chains
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8. Ka Papa ʻInikena Kanaka Makahiki [Pūnaewele]. Bethesda (MD): Ke KeʻenaʻOihana Ola a me nā lawelawe limahana Plasma Cell Neoplasms (Me ka Myeloma Multiple) Hoʻomaʻamaʻa (PDQ®) - Mana Mana Manaʻo; [hoʻohou 2019 Nov 8; haʻi ʻia 2019 Dec 21]; [ma kahi o 3 pale]. Loaʻa mai: https://www.cancer.gov/types/myeloma/patient/myeloma-treatment-pdq
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ʻAʻole pono e hoʻohana i ka ʻike ma kēia pūnaewele i pani no ka mālama olakino ʻoihana a ʻōlelo aʻoaʻo paha. Kāhea aku i ka mea mālama ola inā he nīnau kāu e pili ana i kou olakino.