Mea Kākau: Eugene Taylor
Lā O Ka Hana: 11 Aukake 2021
HōʻAno Hou I Ka Lā: 15 Nowemapa 2024
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Dermatitis Herpetiformis: A Gluten-Related Disorder - Dr. Tom O’Bryan
Wikiō: Dermatitis Herpetiformis: A Gluten-Related Disorder - Dr. Tom O’Bryan

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He aha ka dermatitis herpetiformis?

ʻO ka ʻūlū, ʻulaʻula, ʻāʻī i ka ʻili, dermatitis herpetiformis (DH) kahi ʻano paʻakikī e noho pū me ia. Kū ka ʻūlū a me ka ʻili ma nā kuʻekuʻe, nā kuli, nā ʻili, kua, a me nā puʻupuʻu. Kuhi paha kēia lapuwale i ka hoʻomanawanui ʻole o ka gluten, a pili paha ia i ke ʻano kumu ʻoi loa i ʻike ʻia ʻo ka maʻi celiac. Kāhea ʻia ʻo DH i kekahi manawa ʻo ka maʻi ʻo Duhring a i ʻole gluten rash. Pono nā poʻe i loaʻa kēia ʻano e mālama i ka papaʻai gluten-free koʻikoʻi.

Nā kiʻi o dermatitis herpetiformis

He aha ke kumu o dermatitis herpetiformis?

Mai ke kani o ka inoa, nui ka poʻe e manaʻo i kēia ʻōpala e kekahi ʻano o ka maʻi herpes. ʻAʻole kēia ka hihia, no ka mea ʻaʻohe mea e pili ai i ka herpes. Hana ʻia ka dermatitis herpetiformis i ka poʻe me ka maʻi celiac. ʻO ka maʻi Celiac (i kapa ʻia ʻo celiac sprue, intolerance gluten, a i ʻole enteropathy gluten-sensitive) kahi maʻi autoimmune i hōʻike ʻia e ka hoʻomanawanui ʻole i ka gluten. ʻO Gluten kahi protein i loaʻa i ka palaoa, ka rai, a me ka bale. ʻIke ʻia i kekahi manawa i nā ʻoka i hana ʻia i nā mea kanu e mālama i nā ʻanoʻano ʻē aʻe.


Wahi a ka National Institutes of Health (NIH), 15 a 25 pakeneka o ka poʻe me ka maʻi celiac ka DH. Hiki i ka maʻi Celiac ke hōʻeha i ka ʻeha o ka ʻōpū, ka paʻa ʻana, ka nausea, a me ka luaʻi. ʻAʻole loaʻa i ka poʻe me DH kekahi o nā ʻōpū ʻōpū. Eia nō naʻe, inā ʻaʻole lākou e ʻike i kekahi ʻōpū ʻōpū, 80 pākēneka a ʻoi paha o ka poʻe me DH mau ka pohō o ka ʻōpū, keu hoʻi inā ʻai lākou i ka papaʻai i kiʻekiʻe i ka gluten, e like me ka National Foundation for Celiac Awcious (NFCA).

ʻO ka hōʻino ʻia o ka ʻōpū a me ka wikiwiki ma muli o ka hopena o nā protein gluten me kahi ʻano antibody kūikawā i kapa ʻia immunoglobulin A (IgA). Hana kou kino i nā mea ʻino IgA e hoʻouka i nā protein gluten. Ke hoʻouka kaua nā mea kūpona IgA i ka gluten, hoʻopōʻino lākou i nā ʻāpana o nā ʻōpū e ʻae iā ʻoe e omo i nā wikamina a me nā meaola. Holo pinepine kēia ʻike i ka gluten i loko o nā ʻohana.

Hoʻokumu ʻia nā hale i ka hoʻopili ʻana o IgA i ka gluten a laila komo i ke kahe o ke koko, kahi e hoʻomaka ai lākou e kāpili i nā kīʻaha koko liʻiliʻi, ʻo ka mea hoʻi i ka ʻili. ʻIke ʻia nā hunaola koko keʻokeʻo i kēia mau clogs. Hoʻokuʻu nā hunaola keʻokeʻo i kahi kemika i kapa ʻia ʻo "komplement" e kumu ai i ka ʻūlū, ʻeleʻele blistery.


ʻO wai ka mea e makaʻu ʻole i ka dermatitis herpetiformis?

Hiki i ka maʻi Celiac ke hoʻopili i kekahi, akā ʻoi aku ka maʻamau o ka poʻe i loaʻa kekahi lālā ʻohana me ka maʻi celiac a i ʻole DH.

ʻOiai ʻoi aku ka nui o nā wahine ma mua o nā kāne i ʻike ʻia me ka maʻi celiac, ʻoi aku ka nui o ka ulu ʻana o nā kāne ma mua o ka wahine, e like me ka NIH. Hoʻomaka ka hoʻomaka ʻana o ka ʻōlapa i kou mau 20 a 30 paha, ʻoiai hiki ke hoʻomaka i ka wā kamaliʻi. Kū pinepine ke kūlana i nā poʻe o ko Europa moʻokūʻauhau. Hoʻololi iki ia i ka poʻe kūpuna ʻApelika a me ʻAsia paha.

He aha nā hōʻailona o dermatitis herpetiformis?

ʻO DH kekahi o nā rashes itchiest hiki loa. ʻO nā wahi maʻamau o ka hū e komo pū:

  • kuʻekuʻe lima
  • nā kuli
  • kua malalo
  • kaula lauoho
  • kua o ka ʻāʻī
  • poʻohiwi
  • kīʻaha
  • ʻili poʻo

ʻO ka lapalapa ka nui o ka nui a me ke ʻano ma nā ʻaoʻao ʻelua o ke kino a hele pinepine a hele.

Ma mua o ka laha piha ʻana o ka ʻino, ʻike paha ʻoe i ka ʻili i kahi ʻāʻī prash a kuni paha. ʻO nā peʻa e like me nā pimples piha me ka wai maopopo e hoʻomaka. ʻ scrpala koke ʻia kēia. Hoola nā puʻupuʻu i loko o kekahi mau lā a waiho i kahi māka poni e mau ana no nā pule. Akā ke hoʻomau mau nei i nā puʻupuʻu hou e like me ka hoʻōla o nā mea kahiko. Hiki ke hoʻomau i kēia hana no nā makahiki, a i ʻole hiki ke hele i ke kala ʻana a hoʻi.


ʻOiai pili pinepine kēia mau ʻōuli me ka dermatitis herpetiformis, hiki pū ʻia lākou i nā ʻano ʻili ʻē aʻe e like me atopic dermatitis, hoʻonāukiuki a i ʻole dermatitis pili i nā maʻi āpau, psoriasis, pemphigoid, a i ʻole nā ​​scabies.

Pehea e ʻike ʻia ai ka dermatitis herpetiformis?

Hoʻomaopopo maikaʻi ʻia ʻo DH me kahi biopsy o ka ʻili. Lawe kahi kauka i kahi laʻana o ka ʻili a nānā iā ia ma lalo o kahi microscope. I kekahi manawa, hana ʻia kahi hoʻokolohua pono immunofluorescence, kahi i hoʻopili ʻia ai ka ʻili a puni ka hū me kahi kala e hōʻike ai i ke kū ʻana o nā waihona antibody IgA. Hiki i ka biopsy o ka ʻili ke kōkua i ka hoʻoholo inā loaʻa nā ʻōuli e kekahi ʻano ʻili.

Hiki ke hana ʻia nā hoʻokolohua koko e nānā no kēia mau mea ʻino i loko o ke koko. Hana ʻia kahi biopsy ʻōpū e hōʻoia i ke kū ʻana o ka pōʻino ma muli o ka maʻi celiac.

Inā maopopo ʻole ka hōʻailona, ​​a i ʻole hiki ke loaʻa kahi hōʻike ʻē aʻe, hana ʻia paha nā hoʻokolohua ʻē aʻe. ʻO ka hoʻāʻo patch ka ala ʻoi loa e kuhikuhi ai i ka dermatitis pili i nā maʻi āpau, kahi kumu maʻamau o nā ʻōuli e like me ka dermatitis herpetiformis.

He aha nā hana i loaʻa no ka dermatitis herpetiformis?

Hiki ke mālama ʻia ʻo DH me kahi lāʻau antibiotic i kapa ʻia dapsone. ʻO Dapsone kahi lāʻau lapaʻau ikaika me nā hopena ʻino. Pono e hoʻonui mālie i ka lāʻau i loko o kekahi mau mahina ma mua o ka hopena piha.

ʻIke ka hapa nui o ka poʻe i ke kōkua mai ka lawe ʻana iā dapsone, akā e hoʻopili pū paha nā hopena ʻaoʻao i:

  • nā pilikia ate
  • ʻike maka i ka lā
  • anemia
  • nāwaliwali o nā mākala
  • neuropathy ākea

Hiki paha iā Dapsone ke launa pū me nā lāʻau ʻē aʻe, e like me aminobenzoate potassium, clofazimine, a i ʻole trimethoprim.

ʻO nā lāʻau ʻē aʻe i hiki ke hoʻohana ʻia e komo pū me tetracycline, sulfapyridine, a me kekahi mau lāʻau immunosuppressive. ʻOi aku ka maikaʻi o kēia mau mea ma mua o dapsone.

ʻO ka lapaʻau kūpono loa me ka ʻole o nā hopena ka mālama pono i ka papaʻai gluten-ʻole. ʻO kēia ka mea pono ʻoe e hōʻalo loa i ka meaʻai, inu, a i ʻole nā ​​lāʻau i loaʻa i kēia mau mea:

  • palaoa
  • rai
  • barley
  • ʻoka

ʻOiai paʻakikī ka ukali o kēia papaʻai, e loaʻa ka hopena maikaʻi loa i kou olakino inā loaʻa ʻoe i ka maʻi celiac. Hiki i kekahi hōʻemi ʻana i ka lawe gluten ke kōkua i ka hoʻemi ʻana i ka nui o nā lāʻau āu e pono ai.

He aha nā pilikia o dermatitis herpetiformis?

ʻO ka poʻe me DH a me ka maʻi celiac i hoʻomaʻamaʻa ʻole ʻia e loaʻa i kahi maʻi ʻoi loa ma muli o ka mumū mau o nā ʻōpū. Pilikia paha nā hemahema o ka wikamina a me ka anemia inā ʻaʻole hānai maikaʻi ʻia ka ʻōpū.

ʻOiai ʻo DH kahi maʻi maʻi autoimmune, ua ʻike he pili pū kekahi ia me nā ʻano maʻi autoimmune like ʻole. Pākuʻi ʻia kēia mau mea:

  • hypothyroidism
  • vitiligo
  • ʻano 1 diabetes mellitus
  • myasthenia gravis
  • ʻO Sjögren's syndrome
  • rumatika

He aha ka wā lōʻihi e nānā ai no dermatitis herpetiformis?

He maʻi ʻo DH no ke ola a pau. Hele paha ʻoe i ke kala ʻana, akā i kēlā me kēia manawa ke hōʻike ʻia ʻoe i ka gluten, loaʻa paha iā ʻoe ka maʻi o ka ʻino. Me ka ʻole o ka mālama ʻana, hiki i ka maʻi DH a me celiac ke hopena i nā hopena olakino maikaʻi ʻole, e like me nā hemahema o ka huaora, anemia, a me nā maʻi ʻaʻai gastrointestinal.

Hiki i ka mālama ʻana me dapsone ke kaohi koke i nā ʻōuli o ka hū. Eia nō naʻe, hiki ke mālama wale ʻia ka ʻino o ka ʻōpū e ka maʻi celiac ma ka mālama ʻana i kahi papaʻai gluten-ʻole koʻikoʻi. E nānā pono e kūkā kamaʻilio me nā kauka a me kāu kauka.

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