E ʻike i nā Antipsychotics Maikaʻi no nā Keiki
Anter
- Welina
- Pehea e hana ai nā Antypsychotics Atypical a ʻo wai ka mea e pono ai iā lākou?
- Nā kūlana i mālama ʻia me nā Antypsychotics Atypical
- Schizophrenia
- Bipolar kāna hana
- Aripiprazole (Abilify)
- ʻO Quetiapine (Seroquel)
- ʻO Olanzapine lāua ʻo Risperidone
- Nā maʻi hoʻomohala pālahalaha
- Nā maʻi kūpilikiʻi Disruptive
- Ka palekana o nā Antypsychotics Atypical
- Nā hopohopo palekana me nā antypsychotics atypical i nā keiki a me nā ʻōpio
- Kaumaha Loaʻa
- Nā pilikia puʻuwai a me ka maʻi diabetes
- Ka hana Suicidal
- Nā ʻaoʻao ʻē aʻe
- Koho i kahi Antypsychotic Atypical no nā Keiki
- Kamaʻilio me kāu Kauka
- Pehea mākou e loiloi ai i nā Antipsychotics
- Kaʻana like i kēia hōʻike
- E pili ana iā mākou
- Nā kūmole
- Hōʻuluʻulu Manaʻo
- Hoike piha
ʻO nā lāʻau i kuhikuhi ʻia i kapa ʻia atypical antipsychotics, i hoʻopili ʻia me aripiprazole (Abilify), asenapine (Saphris), clozapine (Clozaril), iloperidone (Fanapt), olanzapine (Zyprexa), paliperidone (Invega), quetiapine (Seroquel), risperidone (risperid) (Geodon), hāʻawi ʻia i nā keiki a me nā ʻōpio e mālama i ka schizophrenia a me ka maʻi bipolar. Hoʻohana ʻia lākou e hoʻāʻo e hoʻoliʻiliʻi i ka huhū, ka huhū, a me nā hana hōʻeha ponoʻī e pili ana i nā maʻi ulu ulu ākea, e like me autism a me Asperger Syndrome, a me nā maʻi disruptive behavior. Akā ʻo ke kuhikuhi ʻana i kēia mau lāʻau i ka poʻe ʻōpio he mea hoʻopaʻapaʻa ia no ka mea ʻaʻole lākou i aʻo maikaʻi ʻia, a ʻike ʻole ʻia ka palekana a me ka maikaʻi o ka wā lōʻihi no nā keiki a me nā ʻōpio.
Ua ʻike ʻia nā noiʻi ʻana i nā mākua hiki i nā antypsychotics atypical ke hana i nā hopena ʻino, no laila ke ʻano hopohopo lōʻihi e pili ana i kā lākou hoʻohana i nā keiki. ʻO kekahi o nā mea hopohopo loa e pili ana i nā neʻe ʻole e kaohi ʻia a me nā haʻalulu e like me ka maʻi o Parkinson (ʻike ʻia e like me nā hōʻailona extrapyramidal), kahi piʻi nui o ka maʻi diabetes, ka loaʻa nui o ke kaupaona, a me nā kiʻekiʻe kolesterol a me nā triglyceride. Hiki i nā lāʻau antypsychotic hōʻino ʻole ke hoʻonui i ka makaʻu o ka make wawe, ma muli o ka hahau ʻana, i nā mākua makua me ka dementia. Ua aʻo mua ʻia kēia mau pilikia i nā mākua; ʻaʻole ʻike maopopo ʻia nā hopena o nā keiki i kēia manawa.
Ma muli o ka nele o ka hōʻike, ʻaʻole hiki iā mākou ke koho i kahi Best Buy atypical antipsychotic no nā keiki me ka schizophrenia, ka maʻi bipolar, nā maʻi hoʻomohala ākea, a i nā maʻi disruptive behavior. Ma kahi o ia mea, koi aku ko mākou mau aʻoaʻo aʻoaʻo i nā mākua e noʻonoʻo pono i nā pilikia a me nā pono kūpono. Pono nā keiki me kēlā mau maʻi e loaʻa i ka lāʻau lapaʻau ākea, e komo pū me ka cognitive behavioral therapy, ka hoʻomaʻamaʻa hoʻokele makua, a me nā papahana aʻo kūikawā, me nā lāʻau hoʻōla lāʻau kūpono.
Ke hoʻoholo nei e hoʻohana i kekahi o kēia mau lāʻau e pono e hana pū ʻia me ke kauka o kāu keiki. ʻO nā mea nui e pili ana i ke kumukūʻai, hiki ke lilo i mea nui, nā hopena ʻē aʻe, a inā paha ua hōʻike ʻia ka hopena o ka lāʻau no ke kūlana a koʻikoʻi paha o kāu keiki. Inā loaʻa i kāu keiki kahi ʻano pilikino e noho nei-e laʻa me ADHD a i ʻole kaumaha - pono ʻoe e ʻike pono e mālama pono ʻia lākou, no ka mea e hoʻomaikaʻi paha kēia i nā hōʻailona o kāu keiki.
Ua paʻi ʻia kēia hōʻike ma Malaki 2012.
Papa Kuhikuhi- Paukū 1: Welina
- Māhele 2: Pehea e hana ai nā Antypsychotics Atypical a ʻo wai ka mea e pono ai iā lākou?
- Māhele 3: Ka palekana o nā Antypsychotics Atypical
- Mahele 4: Ke koho ʻana i kahi Antypsychotic Atypical no nā Keiki
- Māhele 5: Ke kamaʻilio pū ʻana me kāu kauka
- Paukū 6: Pehea mākou e loiloi ai i nā Antipsychotics
- Paukū 7: Kaʻana like ʻana i kēia hōʻike
- Paukū 8: E pili ana iā mākou
- Paukū 9: Nā Kūmole
Welina
Kuhi kēia hōʻike i ka hoʻohana ʻana o nā lāʻau i kuhikuhi ʻia i kapa ʻia he atypical antipsychotics e nā keiki a me nā ʻōpio, 18 a ʻoi paha mau makahiki. Hoʻohana ʻia nā antipsychotics atypical e mālama i ka schizophrenia a me ka maʻi bipolar. Hoʻohana ʻia lākou e hoʻāʻo e hoʻēmi i ka huhū, ka huhū, ka haʻalele ʻana i ka nohona / lepe, a me nā ʻōuli ʻē aʻe i nā keiki a me nā ʻōpio me nā maʻi e ulu nui ana, e like me autism a me Asperger Syndrome, a me nā maʻi disruptive behavior (akā pono e hoʻomaopopo ʻia ʻaʻole pili nā antypsychotics atypical. kōkua i nā pilikia kamaʻilio nui o autism a me nā maʻi like.)
ʻO ka kuhikuhi ʻana i nā keiki a me nā ʻōpio ʻōpio antipsychotic ka mea hoʻopaʻapaʻa no ka mea aia kahi hōʻike liʻiliʻi e pili ana i ka palekana a me ka maikaʻi no ka hoʻohana ʻana i kēia mau makahiki.ʻO ka hapa nui o nā mea a mākou i ʻike ai mai ka hoʻopaʻa ʻana i nā mākua. E like me ka Papa 1 e hōʻike nei, ʻaʻole ʻae ʻia ka hapa nui o nā antypsychotics atypical e ka Food and Drug Administration e hoʻohana ʻia e nā keiki. Akā hiki iā lākou ke hoʻohana ʻia ma ke kānāwai "off-label," ʻo ia hoʻi hiki ke kuhikuhi ʻia ka lāʻau e mālama ai i kahi kūlana ʻaʻohe ona ʻae ʻia e ka FDA. (Nā mea hou aʻe e pili ana i kēia ma ka ʻāpana 2.)
ʻOiai ka nele o ka hōʻike, kuhikuhi pinepine ʻia kēia mau lāʻau i nā keiki a me nā ʻōpio. Ua kōkua kēia i ka hoʻolilo ʻana i nā antypsychotics atypical i ka papa kūʻai lāʻau lapaʻau kiʻekiʻe ʻelima ma ka US ma 2010, me $ 16.1 biliona i ke kūʻai aku, e like me ka IMS Health.
ʻO Clozapine (Clozaril), i loaʻa i ka US ma 1989, ʻo ia ka antypsychotic atypical mua i ʻae ʻia e ka FDA. I kēia lā, hāʻawi wale ʻia ia ke holo ʻole nā lāʻau ʻē aʻe no ka mea hiki ke kumu i kahi maʻi koko koʻikoʻi i kekahi poʻe. Ua ukali ʻia e kekahi mau antypsychotics atypical ʻē aʻe, e like me aripiprazole (Abilify), asenapine (Saphris), iloperidone (Fanapt), olanzapine (Zyprexa), paliperidone (Invega), quetiapine (Seroquel), risperidone (Risperdal), a me ziprasidone (Geodon) . (E nānā i ka Papa 1.)
Hiki i nā antypsychotics atypical ke hoʻonāukiuki i nā hopena hopena, e like me ka paʻakikī o ka muscle, ka neʻe lohi a me nā haʻalulu ʻole (ʻike ʻia he mau hōʻailona extrapyramidal), loaʻa ke kaupaona nui, kahi hoʻonui i ka nui o ka maʻi diabetes type 2, a me nā kiʻekiʻe kolesterol kiʻekiʻe. (Helu ʻia nā hopena ʻaoʻao i ka Papa 2.) ʻAʻole nui nā poʻe e hoʻomaka i ka lawe ʻana i hoʻokahi no ka lōʻihi, ʻoiai e hōʻemi ana i kā lākou mau hōʻailona, no ka mea ʻaʻole hiki a makemake ʻole paha lākou e hoʻomanawanui i nā hopena ʻaoʻao.
ʻO ka hoʻokele ʻana i nā keiki me nā hanana hoʻomohala a i ʻole ke ʻano lawena hiki ke paʻakikī i nā mākua a me nā kauka. Ma muli o ka liʻiliʻi o ka ʻike e pili ana i ka hoʻohana ʻana i nā antypsychotics atypical i nā keiki, a no ka paʻakikī e pili ana i kēlā mau maʻi, ʻaʻole i hōʻike nā Consumer Reports Best Buy Drugs i nā koho lapaʻau kūikawā a i ʻole koho ʻia i kahi Buy maikaʻi loa i kēia hōʻike kūikawā. Akā, loiloi mākou i ka noiʻi olakino e kōkua iā ʻoe e hoʻomaopopo i nā pōmaikaʻi a me nā pilikia o nā antypsychotics atypical i hiki ai iā ʻoe ke hoʻoholo, me ke kauka o kāu keiki, inā kūpono lākou no kāu keiki.
ʻO kēia hōʻike kahi ʻāpana o kahi papahana Consumer Reports e kōkua iā ʻoe e loaʻa nā lāʻau lapaʻau palekana a maikaʻi e hāʻawi iā ʻoe i ka waiwai nui no kāu kālā mālama ola. E aʻo hou aʻe e pili ana i ka papahana a me nā lāʻau ʻē aʻe a mākou i loiloi ai no nā maʻi a me nā kūlana ʻē aʻe, e hele i CRBestBuyDrugs.org.
| Pakuhi 1. Nā lāʻau lapaʻau Antypsychotic Atypical i loiloi ʻia i kēia Hōʻike | |||
|---|---|---|---|
| Inoa Generic | Inoa inoa | Loaʻa Generic | ʻApono ʻo FDA no nā keiki |
| ʻO Aripiprazole | Hoʻomaʻa | Aʻole | ʻAe ʻia no ka hoʻohana ʻia e nā ʻōpio me schizophrenia, nā ʻōpio me ka maʻi bipolar i hui ʻia a i ʻole nā manic episodes, a me ka huhū e pili ana i ka autism. |
| Asenapine | Saphris | Aʻole | Aʻole |
| ʻO Clozapine | ʻO Clozaril Fazaclo | Ae | Aʻole |
| Iloperidone | Fanapt | Aʻole | Aʻole |
| ʻO Olanzapine | Zyprexa Zyprexa Zydis | Aʻole* | Ua ʻae ʻia no ka hoʻohana ʻia e nā ʻōpio me schizophrenia, a me nā ʻōpio me ka maʻi bipolar i hui ʻia a i ʻole nā manic episodes. |
| Paliperidone | Invega | Aʻole | Aʻole |
| ʻO Quetiapine | Seroquel ʻO Seroquel XR | Aʻole* | Ua ʻae ʻia no ka hoʻohana ʻana i ka mālama ʻana i nā keiki me nā manic episodes i ka maʻi bipolar, a me nā ʻōpio me schizophrenia. |
| ʻO Risperidone | Risperdal | Ae | ʻAe ʻia no ka hoʻohana ʻia e nā ʻōpio me schizophrenia, nā ʻōpio me ka maʻi bipolar i hui ʻia a i ʻole nā manic episodes, a no ka huhū e pili ana i ka autism. |
| Ziprasidone | ʻO Geodon | Aʻole | Aʻole |
* Ua hāʻawi ka Food and Drug Administration i ʻae ʻae no ka huahana maʻamau akā ʻaʻohe mea i loaʻa i kēia manawa.
E hoʻi i luna E heluhelu houPehea e hana ai nā Antypsychotics Atypical a ʻo wai ka mea e pono ai iā lākou?
ʻAʻole ʻike maopopo ʻia pehea e hana ai nā antipsychotics e kōkua i ka hōʻoluʻolu i nā ʻōuli. Akā ʻo ka mea a mākou e ʻike ai pili lākou i nā pae o nā kemika i ka lolo i kapa ʻia he neurotransmitters, he kuleana nui i ka hana a me ka noʻonoʻo, a me ka hiamoe, ke ʻano, ka noʻonoʻo, ka hoʻomanaʻo, a me ke aʻo ʻana. ʻO kēia paha kahi e hoʻemi ai i nā hōʻailona psychotic, e like me nā hallucination, nā kuhi hewa, ka noʻonoʻo pono ʻole, a me ka hoʻonāukiuki i ka schizophrenia a me ka maʻi bipolar. E wehewehe paha pehea e hiki ai iā lākou ke hōʻemi i ka huhū, ka huhū, a me nā hana hōʻeha ponoʻī e pili ana i nā maʻi e ulu ākea ana a me nā ʻano hana disruptive. Akā mai nā hōʻike kūpono i kaupalena ʻia, akāka ʻole i ka maikaʻi o kā lākou hana ʻana i kēia, a inā lākou e hoʻomau i ka maikaʻi ma mua o ka wā lōʻihi.
Nā kūlana i mālama ʻia me nā Antypsychotics Atypical
ʻO ka hapa nui o nā noiʻi e pili ana i nā antypsychotics atypical i ka nānā ʻana i ka mālama ʻana i ka schizophrenia a me ka maʻi bipolar. Ua ʻae ʻia kahi lāʻau e kekahi o nā lāʻau i loko o nā keiki a me nā ʻōpio a me nā mākua. Akā ua hoʻohana ʻia lākou me ka "off-label," ʻo ia hoʻi ua kuhikuhi ʻia lākou e nā kauka e mālama i nā kūlana i ʻae ʻole ʻia e FDA.
He hana maʻamau a kau ʻia ke kānāwai e nā kauka, ʻoiai he kū ʻole i nā ʻoihana lāʻau e hoʻolauna i kā lākou lāʻau no ka hoʻohana inoa ʻole. Hoʻohana ʻia ka inoa waho no nā antypsychotics atypical i nā keiki e pili ana i ka mālama ʻana i nā maʻi hoʻomohala ākea, e like me autism a me Asperger Syndrome, a me nā maʻi disruptive behavior. (ʻAe ʻia ʻo Aripiprazole a me risperidone no ka poʻe me nā maʻi autism-spectrum, akā ʻaʻole nā antipsychotics ʻāpiki ʻē aʻe.)
No nā kūlana ʻehā-bipolar maʻi, schizophrenia, nā maʻi hoʻomohala ākea, a me nā maʻi kūpilikiʻi disruptive-ʻo nā hōʻike e kākoʻo ana i ka hoʻohana ʻana i nā antypsychotics atypical e nā ʻōpio i kaupalena ʻia i kekahi mau, haʻawina wā pōkole liʻiliʻi, me ka ʻole o nā hōʻike maikaʻi maikaʻi ma ka lōʻihi -term pono a me ka palekana.
Ma ke ʻano holoʻokoʻa, ua pili nā noiʻi ʻana i ka hoʻohana atypical antipsychotics e nā keiki ma kahi o 2,640 wale nō o lākou. Ma kahi o 1000 mau keiki i loaʻa i ka maʻi bipolar, 600 i loaʻa i nā maʻi developmental pervasive, 640 i loaʻa i nā maʻi disruptive behavior, a ʻoi aku ma mua o 400 i loaʻa ka schizophrenia.
Hōʻike ka pahu ma ka ʻāpana 2 i nā lāʻau i aʻo ʻia i nā keiki, a no nā ʻano hea. ʻO ka aripiprazole (Abilify), olanzapine (Zyprexa), quetiapine (Seroquel), a me risperidone (Risperdal) i hoʻopaʻa ʻia i nā keiki me ka maʻi bipolar. I nā ʻōpio me ka schizophrenia hoʻomaka hou, ua aʻo wale ʻia ʻo olanzapine (Zyprexa), quetiapine (Seroquel), a me risperidone (Risperdal). Ua aʻo ʻia ʻo Aripiprazole (Abilify), olanzapine (Zyprexa), a me risperidone (Risperdal) i nā keiki me nā maʻi e ulu pono ana, ʻoiai ʻo risperidone (Risperdal) wale nō i hoʻopaʻa ʻia i loko o nā keiki me nā ʻano ʻano disruptive behavior.
No kēlā me kēia kūlana i nā keiki, hōʻike pololei ka hoʻohālikelike ʻana i kekahi antypsychotic atypical i kekahi mea palena ʻole ʻole ʻia. ʻO nā hōʻike no ka pono a me ka pōʻino i ʻōlelo ʻia ma lalo e ke ʻano no kēlā me kēia lāʻau.
Schizophrenia
ʻAʻole maopopo i ka nui o nā keiki e ʻeha i ka schizophrenia no ka mea ʻaʻole ʻike pinepine ʻia ka maʻi a hiki i ka wā makua, e like me ka National Institute of Mental Health. Ua ʻike ʻia ʻo Schizophrenia i loko o nā keiki ma mua o 5 akā paʻakikī loa kēia. ʻIke pinepine nā kāne i nā ʻōuli mua i ka ʻōpio o ko lākou ʻōpio a i ka wanaʻao a waena o 20; ʻike pinepine ʻia nā wahine ma kā lākou 20s a mid-30s.
ʻEha ka poʻe me schizophrenia i ka noʻonoʻo kolohe a me ka noʻonoʻo ʻole, akā kūʻē i ka manaʻo nui, ʻaʻohe o lākou ʻano pilikino. Ua huki ʻia paha lākou, makaʻu, a hoʻonāukiuki hoʻi, a ʻike i nā hiʻohiona a me nā kuhi hewa. A he paʻakikī paha kā lākou e pili ana i ka naʻau i kekahi.
Noho nā kānaka he nui me schizophrenia i nā ola kūpono a hana maikaʻi me ka lāʻau kūpono. ʻO ka hapa nui o nā noiʻi o nā lāʻau antypsychotic atypical i kau i ka poʻe mākua me ka schizophrenia. Ua loaʻa lākou e kōkua i ka hōʻemi ʻana i nā ʻōuli, hoʻomaikaʻi i ke ʻano o ke ola, a hoʻemi i ka manawa o ke kanaka e hana ʻino iā ia iho a i kekahi poʻe ʻē aʻe paha. Akā ʻo nā haʻawina e pili ana i ka hoʻohana antpsychotics e ka poʻe ʻōpio nona ka maʻi schizophrenia i ʻike koke ʻia ua kaupalena ʻia.
| ʻO nā Antypsychotics Atypical i aʻo ʻia i nā keiki a me nā ʻōpio, e nā maʻi | |||||
|---|---|---|---|---|---|
| Inoa Generic | Inoa inoa | Kūleʻa | |||
| ʻO nā keiki me ka maʻi bipolar | ʻO nā ʻōpio me ka schizophrenia hoʻomaka hou | ʻO nā keiki me nā maʻi kūpilikiʻi | ʻO nā keiki me nā maʻi e ulu ākea ana | ||
| ʻO Aripiprazole | Hoʻomaʻa | & nānā; | & nānā; | ||
| ʻO Olanzapine | Zyprexa | & nānā; | & nānā; | & nānā; | |
| ʻO Quetiapine | Seroquel | & nānā; | & nānā; | ||
| ʻO Risperidone | Risperdal | & nānā; | & nānā; | & nānā; | & nānā; |
& nānā; hōʻike i ka lāʻau i aʻo ʻia ma ke ʻano he lapaʻau no kēlā maʻi maʻi i nā keiki a me / a i ʻole ʻōpio. ʻAʻole helu ʻia ʻo Asenapine (Saphris), Clozpine (Clozaril), iloperidone (Fanapt), paliperidone, a me ziprasidone (Geodon) no ka mea ʻaʻole i aʻo ʻia i nā keiki.
Hōʻike nā noiʻi o nā mākua ma kahi o ka hapalua o ka poʻe me schizophrenia e ʻike i kahi hōʻemi kūpono i kā lākou mau hōʻailona ma hope o ka lawe ʻana i kahi antipsychotic. ʻO kekahi mau hōʻailona, e like me ka hoʻonāukiuki, e ʻoi aku paha ka maikaʻi i loko o kekahi mau lā. ʻO nā mea ʻē aʻe, e like me nā kuhi hewa a me nā hallucination, hiki ke lawe i ʻehā a ʻeono pule e maʻalahi ai. ʻO ka hopena, kokoke i kēlā me kēia kanaka i ʻike ʻia me ka schizophrenia e loaʻa kahi lāʻau antipsychotic.
Akā ʻaʻole hana nā antypsychotics atypical no nā mea āpau. Ma kahi o 20 pākēneka o ka poʻe me ka schizophrenia e loaʻa ʻole kahi pōmaikaʻi mai iā lākou, a ʻo kahi 25 a 30 mau pākēneka ʻike wale i ka hoʻoliʻiliʻi hapa o nā hōʻailona.
ʻElua mau haʻawina liʻiliʻi i hoʻohālikelike pololei i ka hopena o nā antypsychotics atypical i hoʻohana ʻia e nā ʻōpio me ka schizophrenia ʻaʻole i loaʻa nā ʻokoʻa nui ma waena o nā lāʻau i hoʻāʻo ʻia. Ua like ka hopena o Olanzapine (Zyprexa) a me quetiapine (Seroquel) i nā ʻōuli ma hope o ʻeono mau mahina i kahi aʻo liʻiliʻi loa o nā ʻōpio i loaʻa nā diagnose hou o ka schizophrenia. ʻO Risperidone (Risperdal) a me olanzapine (Zyprexa) i alakaʻi i nā hoʻomaikaʻi like i nā hōʻailona ma luna o ʻewalu pule.
Bipolar kāna hana
ʻO ka hapa nui o nā poʻe me ka maʻi bipolar hāʻawi pinepine ʻia i kahi hōʻailona i ko lākou mau makahiki ʻōpio a i ʻole 20 mau makahiki. Kuhi ka National Institute of Mental Health ua pili ke ʻano ma lalo o 3 pākēneka o nā ʻōpio, akā ʻaʻole ʻike ʻia ka prevalence kikoʻī no ka mea he paʻakikī ka maʻi e hōʻoia i nā keiki. He hapa kēia ma muli o ka maopopo ʻole o nā ʻōuli i nā keiki ma mua o nā mākua, a hiki iā lākou ke hoʻopili me nā ʻano kamaliʻi ʻē aʻe, e like me ADHD a i ʻole maʻi maʻi.
ʻO nā ʻōuli ʻōuli o ka maʻi bipolar ka ʻūlū ʻoi loa ma waena o nā ʻano kiʻekiʻe loa-a i ʻole mania-a me nā ʻano haahaa loa-a i ʻole ke kaumaha. I ka hapanui o nā hihia, kū mau kēlā mau mea i ke ʻano no kekahi mau pule. Aia kekahi ma waena o ka wā me ka naʻau “maʻamau”. Akā ʻo kekahi poʻe me ka maʻi bipolar paha he mau manawa kahi e loaʻa ai nā hōʻailona o ka mania a me ke kaumaha i ka manawa like. Kapa ʻia kēia mau māhele he "hui".
ʻAʻole hoʻohana pinepine ʻia nā antypsychotics atypical e mālama ai i ka maʻi bipolar a hiki i ka hoʻāʻo mua ʻana o ka poʻe i nā lāʻau ʻē aʻe, e like me ka lithium, divalproex, a me ka carbamazepine.
Ua ʻike nā noiʻi o nā mākua i nā antipsychotics āpau ke kōkua i ka hōʻemi ʻana i nā hōʻailona mania o ka maʻi bipolar, me 40 a 75 pakeneka o ka poʻe e ʻike nei i ka emi ʻana o nā ʻōuli. Akā ua liʻiliʻi nā noiʻi e pili ana i ka hopena o nā lāʻau i nā mākua me ka maʻi bipolar ma mua o ka schizophrenia, a ʻoi aku ka liʻiliʻi i waena o nā keiki me ka maʻi bipolar.
Eia ka mea i ʻike ʻia i kēia manawa:
Aripiprazole (Abilify)
I hoʻokahi noiʻi, pane manawa pōkole-ʻo ia hoʻi he 50 pākēneka a ʻoi paha ka hōʻemi o nā hōʻailona-i ʻike ʻia ma 45 i ka 64 pākēneka o nā keiki a me nā ʻōpio e lawe ana i ka aripiprazole ma hope o ʻehā mau pule o ka hoʻomaʻamaʻa hoʻohālikelike ʻia me 26 pakeneka i lawe i kahi placebo. Remission-kahi hopena kokoke loa o nā ʻōuli- i loaʻa ma 25 a 72 pakeneka o nā keiki e lawe ana i ka aripiprazole me 5 a 32 pākēneka ma kahi placebo. Akā i ka hopena o ke aʻo ʻana, hōʻike nā keiki i ka aripiprazole i ka maikaʻi o ko lākou ola ma mua o ka poʻe i mālama ʻia me kahi placebo.
ʻO Quetiapine (Seroquel)
I hoʻokahi noi, 58 i ka 64 pakeneka o nā keiki a me nā ʻōpio me nā ʻōuli mania i hōʻike i kahi pane ma hope o ʻekolu mau pule o ka mālama ʻana me ka quetiapine i hoʻohālikelike ʻia me 37 pākēneka i lawe i kahi placebo. Ua ʻike ʻia ke kala ʻana ma mua o ka hapalua i lawe i ka quetiapine i hoʻohālikelike ʻia me 30 pākēneka ma kahi placebo.
I ka manawa i hoʻohana ʻia ai ka quetiapine me kahi lāʻau ʻē aʻe, di - valproex, e nā ʻōpio me nā mana mania koʻikoʻi, ua hōʻike ʻia he 87 pākēneka i kahi pane ma hope o ʻeono mau pule i hoʻohālikelike ʻia me 53 pākēneka i lawe i ka divalproex wale nō. Ma kahi noiʻi ʻē aʻe i hoʻohālikelike i ka quetiapine i ka divalproex i nā ʻōpio me ka maʻi bipolar, ua hopena nā lāʻau ʻelua i ka hoʻomaikaʻi ʻana o ke ola i ka hopena o ʻehā mau pule. Ua ʻike ʻia nā hoʻomaikaʻi i ko lākou hiki ke launa pū me nā poʻe ʻē aʻe a hoʻokele i kā lākou ʻano, a ʻoi aku ka liʻiliʻi o nā haunaele i ke ola ʻohana. A ua ʻōlelo nā mākua o ka poʻe ma quetiapine ua ʻoi aku ka maikaʻi o kā lākou mau keiki i ke kula, ma ka pilikanaka a me ka noʻonoʻo, a ua ʻoi aku ka maikaʻi no lākou iho.
ʻAʻole ʻoi aku ka maikaʻi o Quetiapine ma mua o kahi placebo ke hiki mai i nā wā kaumaha o ka maʻi bipolar. I ke aʻo ʻana i 32 mau ʻōpio me kahi hanana depressive e pili ana i ka maʻi bipolar, ʻaʻole i alakaʻi ʻia ka quetiapine i nā hoʻomaikaʻi ʻana i nā ʻōuli a i ʻole ka hoʻomaikaʻi hou ʻia ʻana ma hope o ʻewalu mau pule o ka hoʻomaʻamaʻa ke hoʻohālikelike ʻia me kahi placebo.
ʻO Olanzapine lāua ʻo Risperidone
Hoʻohālikelike kahi haʻawina liʻiliʻi i ka risperidone (Risperdal) a me ka olanzapine (Zyprexa) ma 31 keiki kamaliʻi me nā maʻi bipolar e hōʻike nei i nā hōʻailona mania. Ua hōʻike ʻia nā lāʻau e like me ka maikaʻi i ka hoʻopakele ʻana i nā ʻōuli ma hope o ʻewalu pule o ka mālama ʻana. Pono kahi aʻo nui e hōʻoia i kēlā mau hopena.
Ua ʻike ʻia nā noiʻi o nā ʻōpio me nā ʻōuli mania he 59 a 63% pākēneka i lawe iā risperidone (Risperdal) no ʻekolu mau pule i ʻike i kahi pane ke hoʻohālikelike ʻia me 26 pākēneka i lawe i kahi placebo. Ma kahi noi like me olanzapine (Zyprexa), 49 pakeneka o nā ʻōpio e lawe ana i ka lāʻau i hōʻike i kahi pane i hoʻohālikelike ʻia me 22 pākēneka i lawe i kahi placebo. Ua ʻike pū kekahi nā noiʻi ʻelua i ka risperidone a me ka olanzapine i loaʻa i ka nui o nā mea maʻi e ʻike i ke kala ke hoʻohālikelike ʻia me kahi placebo.
Nā maʻi hoʻomohala pālahalaha
ʻO nā maʻi hoʻomohala pālahalaha pū kekahi me nā maʻi maʻi autism (autism a me Asperger Syndrome) a ʻo Rett Syndrome, maʻi maʻi disintegrative o ke keiki, a me nā maʻi hoʻomohala ākea āpau (i kapa pinepine ʻia ʻo "maʻi ulu ulu, ʻaʻole hōʻike ʻia").
Ma ka awelika, hoʻokahi o 110 mau keiki i ka U.S. i kekahi ʻano o ka maʻi autistic, e like me nā Centers for Disease Control and Prevent. ʻO Autism, ka mea maʻamau i nā keikikāne ma mua o nā kaikamahine, ʻike pinepine ʻia ma mua o ka makahiki 3. ʻAʻole ʻike ʻia ke kumu. Pilikia ka poʻe me ka autism me ka mākau kamaʻilio a me ke kamaʻilio ʻana, a me ka pānaʻi o ka naʻau, a hōʻike lākou i ka hana kapu, a me nā hana hou, nā hana, a me nā makemake.
ʻAʻohe lāʻau lapaʻau, akā aia kekahi mau hōʻailona i hiki ke kōkua. Hoʻonohonoho ʻia nā papahana aʻo a i ʻole i kēlā me kēia lā e kia ana i ka hoʻonui ʻana i ka mākau a me nā hoʻolālā kamaʻilio e hoʻohana maʻamau ʻia, me nā ʻenehana hoʻokele lawena a me ka hoʻomaʻamaʻa behavioral cognitive. Kau ʻia nā antipsychotics, inā pono, me ka pahuhopu e hōʻemi i ka hana disruptive, e like me hyperactivity, impulsivity, huhū, a me nā hana hōʻeha ponoʻī. Hoʻohana ʻia nā lāʻau ʻē aʻe e mālama ai i nā maʻi ʻē aʻe, e like me ka hopohopo a me ke kaumaha.
Kakaʻikahi nā noiʻi i nānā i ka hoʻohana ʻana o antipsychotics e nā keiki me kēia mau maʻi. ʻO ka noi nui loa, e pili ana i nā keiki 101 me ka maʻi o ka hoʻomohala ākea, ʻike ʻia he 69 pakeneka o ka poʻe i lawe i ka risperidone (Risperdal) i helu ʻia "hoʻomaikaʻi maikaʻi" ma hope o ʻewalu mau pule o ka hoʻomaʻamaʻa hoʻohālikelike ʻia me 12 pākēneka i lawe i kahi placebo. ʻO Risperidone (Risperdal) ʻo ia wale nō ka antypsychotic atypical i aʻo ʻia i nā keiki o ke kula kamaliʻi me ka maʻi e ulu pono ana, akā ʻaʻole i ʻike ʻia ʻoi aku ka maikaʻi ma mua o kahi placebo.
ʻAʻole maopopo inā hope nā pōmaikaʻi o risperidone ma kahi o ka wā lōʻihi. Hōʻike nā palena palena palena ʻole ma hope o ʻehā mau mahina o ka mālama ʻana, 10 pākēneka o nā keiki e hōʻike i ka hoʻomaikaʻi e hōʻoki i ka lawe ʻana i ka lāʻau no ka mea ʻaʻohe hopena a i ʻole ʻike lākou i nā hopena ʻaoʻao. Ua alakaʻi kēia i ka hoʻi hou ʻana - hoʻi o nā hōʻailona i kā lākou pae mua-i ka 63 pākēneka, akā ʻo 13 wale nō ka pākēneka o ka poʻe i hoʻomau i ka lawe ʻana i ka lāʻau i ʻelua mau mahina i hoʻi hou.
I loko o ʻelua mau noiʻi e pili ana i nā keiki 316, ʻo ka poʻe i lawe i ka aripiprazole (Abilify) ʻaʻole e hōʻeha iā lākou iho a hōʻike i ka huhū i kekahi poʻe ke hoʻohālikelike ʻia me ka poʻe i loaʻa kahi placebo. ʻAʻole lākou i huhū, ua liʻiliʻi ka huhū huhū, ua loaʻa i nā loli o ka naʻau a i ʻole nā ʻano kaumaha, a ʻoi aku ka liʻiliʻi o ka ʻuwī ʻana a me ka ʻuwē kūpono ʻole ʻana.
Loaʻa nā hōʻike palena palena loa i ka hoʻohana ʻia o olanzapine (Zyprexa) e nā keiki me nā maʻi e ulu ākea ana. Loaʻa ʻelua mau noiʻi e pili ana ma lalo o 25 mau keiki. Hōʻike nā hopena i ʻoi aku ka olanzapine ma mua o kahi placebo a like me ka antoperikotik haloperidol kahiko (Haldol). Akā ma muli o ka hapa liʻiliʻi loa o nā keiki i hoʻopaʻa ʻia, pono nā noiʻi nui e hoʻoholo inā hiki ke hoʻohana ākea ʻia kēlā mau hopena i nā keiki me nā maʻi ulu ākea.
Nā maʻi kūpilikiʻi Disruptive
ʻO nā maʻi kūpilikiʻi kūpilikiʻi me nā maʻi kūʻē kūʻē, kūleʻa, a me nā ʻano maʻi disruptive maʻamau (i kapa ʻia i nā puke olakino "maʻi kolohe, ʻaʻole i kuhikuhi ʻia"). Kū ka maʻi kūʻē kūʻē kūʻē ʻia ma kahi o 1 a 6 pākēneka o ka ʻōpio, a kū ka maʻi maʻi ma kahi o 1 a 4 pakeneka.
ʻO nā ʻōuli i ʻike ʻia i loko o nā keiki i ʻike ʻia me ka maʻi kūʻē kūʻē e komo pū me ka inaina, negativism, a me ka hoʻowahāwahā i ka luna. Hōʻike ʻia ma mua o ka makahiki 8, a ʻoi aku ka maʻamau o nā keikikāne. I kekahi mau hihia, hiki ke hoʻonui i ke koʻikoʻi o nā ʻōuli me ka makahiki a lilo i ʻano nui o ka maʻi maʻi. ʻO nā keiki i ʻike ʻia me nā maʻi disruptive e hōʻike pinepine i ka deficit attention / hyperactivity maʻi (ADHD).
Hōʻike nā keiki me ka maʻi maʻi i kahi ʻano o ka hakakā i ka poʻe a me nā holoholona, ka hōʻino a me / a ʻaihue paha o ka waiwai, a me nā hana hewa ʻē aʻe i hōʻeha ʻia, me ka ʻole o ka minamina. Hoʻomaʻamaʻa pinepine ʻia ka maʻi alakaʻi ma mua o ka piha ʻana o nā makahiki 16, a ʻoi aku ka maʻamau o nā keikikāne. Pili nā maʻi kūʻē ʻelua kūʻē a me nā maʻi i nā pilikia nui e hana ana ma ka home, ma ke kula, a ma hope, ma ka hana. ʻIke pinepine nā keiki me nā maʻi kūʻē kūʻē i nā pilikia aʻo i ke kula, a loaʻa pinepine i nā pilikia kū kānāwai ma ke ʻano he poʻe mākua.
ʻO nā keiki me nā ʻano like, akā ʻoi aku ka paʻakikī, nā ʻano o ka lawena, i hoʻohālikelike ʻia me nā mea kūpaʻa kūʻēʻē a hana ʻino paha, e ʻike ʻia me ka maʻi maʻamau disruptive a i ʻole nā ʻano disruptive behavior, ʻaʻole i kuhikuhi ʻia. Hōʻike nā keiki me kēia ʻano i ka pilina pilikino a me ka pilina ʻohana, a me / a i ʻole nā kula i hoʻopilikia ʻia.
ʻO ka hana mua o nā maʻi disruptive ka ʻohana a hoʻokumu ʻia me ka hoʻomaʻamaʻa hoʻokele makua. Manaʻo ʻia ka lāʻau lapaʻau mea hoʻohui a kuhikuhi ʻia i nā ʻōuli kikoʻī. I ka hoʻoholo e hoʻomaka i kahi lāʻau, he mea nui ia e noʻonoʻo i nā ʻano ʻē aʻe a ke keiki. ʻO kahi laʻana, pono paha nā lāʻau ADHD inā loaʻa i kahi keiki kahi maʻi hoʻoluhi a me ADHD. I nā keiki me ka maʻi kū, hiki ke kōkua i nā mea hoʻonāukiuki, e like me ka lithium a me ka valproate. Kau ʻia nā antipsychotics i nā keiki me nā maʻi disruptive e hōʻemi i ka huhū e pili ana i kēia mau ʻano, akā ʻelua wale nō antipsychotics-risperidone a me quetiapine i hoʻopaʻa ʻia no kēia hoʻohana. ʻAʻohe o nā lāʻau antipsychotic i ʻae ʻia e ka FDA no ka mālama ʻana i nā ʻano maʻi disruptive.
I ke aʻo ʻana i nā keiki me nā ʻōuli maʻi ʻōuli maikaʻi loa, ʻo ka poʻe i loaʻa iā risperidone ua hōʻike ʻia ma kahi o ʻelua mau manawa ka nui o ka hoʻomaikaʻi ʻana i nā hana pilikia ma mua o ʻeono a 10 mau pule o ka hoʻomaʻamaʻa hoʻohālikelike ʻia me ka poʻe i lawe i kahi placebo. Ma kahi o 27 pākēneka o nā keiki i hoʻomau i ka lawe ʻana i ka risperidone no ʻeono mau mahina ua hoʻi hou kahi hoʻohālikelike ʻia me 42 pākēneka o nā keiki i loaʻa ʻole ka lāʻau, akā ua hoʻemi ke degere o ka hoʻomaikaʻi i nā hui ʻelua.
I ke aʻo ʻana i nā ʻōpio me nā ʻōuli disruptive e pono ai i ka haukapila, ua hoʻomaikaʻi ʻo risperidone i kā lākou loiloi holoʻokoʻa, me 21 pākēneka i helu ʻia ma ke ʻano he "koʻikoʻi a weliweli loa" i hoʻohālikelike ʻia me 84 pakeneka e lawe ana i kahi placebo.
ʻAʻole i loaʻa ka maikaʻi o Quetiapine (Seroquel) i ka hoʻomaikaʻi ʻana i ka hana kūpilikiʻi e pili ana i ka maʻi o ka noho ʻana. I loko o kahi aʻo wale nō i loaʻa, ʻaʻole i ʻoi aku ka maikaʻi o ka quetiapine ma mua o kahi placebo e hoʻemi ana i ka huhū a me ka hyperactivity i nā ʻōpio me ka maʻi o ke ʻano a me ka lawena hakakā kūpikipiki a koʻikoʻi. ʻO kekahi o nā keiki ʻeiwa (11 pākēneka) i hoʻōki i ka lawe ʻana i ka lāʻau ma muli o ka akathisia, kahi hopena e hōʻike ai i ka poʻe me he mea lā ʻaʻole hiki iā lākou ke noho mālie. ʻOi aku ʻo Quetiapine i kahi placebo ma nā ana ākea o ka hoʻomaikaʻi ʻana i nā ʻōuli a me ke ʻano o ke ola.
E hoʻi i luna E heluhelu houKa palekana o nā Antypsychotics Atypical
Hiki i nā antypsychotics atypical ke kumu i nā hopena ʻaoʻao nui, ka mea e kaupalena ai i ko lākou pono holoʻokoʻa. (E nānā i ka Papa 2, ma lalo.) Nui nā poʻe e hoʻomaka i ka lawe ʻana i hoʻokahi ʻaʻole lawe no ka lōʻihi, ʻoiai inā hoʻemi ia i ko lākou mau hōʻailona, no ka mea ʻaʻole hiki a makemake ʻole paha lākou e hoʻomanawanui i nā hopena ʻaoʻao. Eia kekahi, ʻo ka poʻe me ka schizophrenia a me ka maʻi bipolar hikiwawe loa i ka hoʻōki ʻana i kā lākou lāʻau no ke ʻano o ko lākou maʻi. ʻAʻole maopopo iā lākou he maʻi psychiatric kā lākou, ʻaʻole ʻae i ke kōkua ʻana iā lākou mai nā lāʻau, hoʻopoina i ka lawe ʻana, a haʻalele paha i ka lawe ʻana ke maʻalahi nā ʻōuli koʻikoʻi.
ʻO kahi hopena ʻino o ka antypsychotics atypical ka pili o ka neʻe (extrapyramidal) - nā leka uila a me nā haʻalulu e like me ka maʻi o Parkinson. E hele keu nā hopena Extrapyramidal ke hoʻopau ʻia ka lāʻau a hoʻohaʻahaʻa ʻia ke ana. Akā hiki i kahi maʻi neʻe kikoʻī i kapa ʻia ʻo tardive dyskinesia ke ulu me ka hoʻohana lōʻihi a hoʻomau paha ma hope o ka pau ʻana o ka mea maʻi i ka lawe ʻana i ka antipsychotic.
Hoʻokomo pū ʻia nā lāʻau antypsychotic hōʻino kino ʻole i nā hopena ʻē aʻe koʻikoʻi, e like me ka hoʻonui ʻana o ka maʻi diabetes type 2, ka nui o ke kaumaha, a me nā kiʻekiʻe kolesterol a me nā triglyceride. Hoʻohui ʻia, ua ʻike ʻia lākou e hoʻonui i ka makaʻu o ka make wawe, ma muli o ka hahau ʻana, i nā mākua makua me ka dementia. Ua aʻo mua ʻia kēia mau pilikia i nā mākua; ʻaʻole ʻike maopopo ʻia nā hopena o nā keiki i kēia manawa.
| Papa 2. Nā ʻaoʻao ʻaoʻao i hui pū ʻia me nā Antypsychotics Atypical | |
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| Nā Liʻiliʻi i nā ʻaoʻao ʻino ʻino - Hiki i kēia mau mea ke maʻalahi a nalo paha i ka manawa, a hoʻoliʻiliʻi hoʻi inā e hoʻohaʻahaʻa ʻia ka lāʻau. Hele lākou ke pau ka lāʻau. ʻO ka papa inoa ma lalo ka pīʻāpā a ʻaʻole no ke ʻano o ka nui, ke koʻikoʻi, a me ke alapine. ʻO ka hapa nui o ka poʻe i ʻoi aku ma mua o hoʻokahi o kēia mau hopena. Akā ʻo ka ʻike me, a me ke koʻikoʻi o, nā hopena ʻokoʻa i loli ʻia e ka kanaka. | |
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| Nā ʻaoʻao ʻē aʻe paha ka hopena - Koi paha kēia i ka hoʻopau ʻana i ka lāʻau a i ʻole ka hoʻololi ʻana i kahi ʻokoʻa. Hoʻohuli pinepine ʻia lākou, akā hiki, i kekahi mau hihia, lilo i paʻa, a, i ka hihia o agranulocytosis, a me ka hoʻoweliweli ola. | |
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Hoʻohui mua ʻia me ka clozapine; koi ʻia nā hoʻokolohua koko maʻamau i ka wā e lawe ana.
Ma ke ʻano holoʻokoʻa, 80 a 90 pākēneka o nā mākua e lawe i ka antipsychotic o kēlā me kēia ʻano e loaʻa ma ka liʻiliʻi i hoʻokahi ʻaoʻao ʻaoʻao; ka hapanui e loaʻa i kahi o hoʻokahi. ʻO nā mea ʻike i nā hopena ʻaoʻao:
- 20 a 30 pākēneka e loaʻa i kahi hopena maikaʻi ʻole a hoʻomanawanui ʻole hoʻi a hooki i ka lawe ʻana i ka lāʻau i loko o nā lā, mau pule, a i ʻole kekahi mau mahina.
- 35 a 45 pakeneka e hōʻoki i ka lawe ʻana i ka lāʻau i loko o ʻeono mau mahina.
- 65 a 80 pākēneka e pau ka lawe ʻana i ka lāʻau i loko o 12 a 18 mau mahina.
Nā hopohopo palekana me nā antypsychotics atypical i nā keiki a me nā ʻōpio
Ma muli o ke kaupalena ʻia o nā noiʻi a nā keiki a me nā ʻōpio, ʻaʻole ʻike maopopo ʻia nā hopena maikaʻi ʻole o nā antypsychotics atypical. Hoʻololi ka ʻaoʻao ʻaoʻao i ka lāʻau lapaʻau, no laila ke noʻonoʻo nei i hoʻokahi no kāu keiki, pono e noʻonoʻo ʻia nā makaʻi o kēlā me kēia lāʻau kikoʻī e kūʻē i ka pono kūpono. ʻO nā ʻāpana aʻe kahi hōʻike o nā hopena i loaʻa i nā noiʻi e pili ana i nā keiki a me nā ʻōpio.
Kaumaha Loaʻa
ʻO ka loaʻa ʻana o ke kaupaona ka hopena hopena maʻamau e pili pū me nā antypsychotics atypical i lawe ʻia e nā keiki a me nā ʻōpio. Hāʻawi ʻia ʻo Risperidone (Risperdal) ma nā kaha haʻahaʻa, no ka laʻana, alakaʻi i kahi awelika o ke kaupaona ma kahi o 4 mau paona i nā keiki me nā maʻi e ulu ākea ana a i ʻole nā ʻano hana disruptive i hoʻohālikelike ʻia me nā mea i hāʻawi ʻia i kahi placebo. ʻAʻole maopopo inā paʻa a hoʻomau paha ka hoʻonui ʻana o kēia kaumaha ma luna o ka longterm. Hōʻike nā hōʻike o kēia manawa i ka hoʻomau ʻana o ke kaupaona, me nā koho o 4 a 12 mau paona i hoʻokahi makahiki a hiki i 18 mau paona ma hope o ʻelua mau makahiki.
ʻO ke kaupaona ʻana ka hopena pilikia loa me ka aripiprazole (Abilify). I hoʻokahi noi, 15 pākēneka o nā keiki e lawe ana iā ia i loaʻa i kahi loaʻa kaumaha koʻikoʻi (ma ka liʻiliʻi 7 pākēneka ma mua o ka hoʻomaka ʻana o ke kaupaona) ma luna o ʻewalu pule I loko o kahi noi ʻē aʻe, 32 pākēneka o nā keiki i ʻike i ka loaʻa ʻana o ke kaumaha i ka wā ma aripiprazole. I nā haʻawina ʻelua, ʻike nā keiki i kahi placebo i ka loaʻa ʻana o ke kaupaona i hoʻowahāwahā ʻia. Inā hoʻomau ka loaʻa ʻana o ke kaupaona me ka aripiprazole ma kahi o ka wā lōʻihi maopopo ʻole no ka mea ʻaʻohe loaʻa nā loiloi lōʻihi o ke kaupaona ʻana me ka hoʻomau hoʻomau ʻana.
Hoʻopili pū ʻia ʻo Olanzapine (Zyprexa) me ka waiwai kaupaona, me nā keiki e loaʻa ana he 7.5 a 9 mau paona ma kahi o ʻeono a 10 mau pule o ka mālama ʻana. Hoʻokahi o nā noi i loaʻa he ʻelua hapakolu o nā keiki i loaʻa ma ka liʻiliʻi he 7 pākēneka ma mua o ko lākou hoʻomaka kaumaha. E like me ka hihia me ka aripiprazole (Abilify), ʻaʻole loaʻa nā haʻawina o ke kaupaona i nā keiki e hoʻomau i ka lawe ʻana i ka olanzapine no kahi wā lōʻihi.
| Pakuhi 3. Kaumaha Loaʻa me nā Antypsychotics Atypical i nā Keiki a me nā ʻōpio | |||
|---|---|---|---|
| Laau lāʻau | Loaʻa ka paona ma nā paona ma mua o 6 a 8 mau pule | ||
| ʻO ka maʻi hoʻomohala pervasive a i ʻole kahi Disruptive Behaviour Disorder | Bipolar kāna hana | Schizophrenia | |
| Aripiprazole (Abilify) | 3-4 | <1 | – |
| Olanzapine (Zyprexa) | 7.5 a 9 | 7.4 | – |
| ʻO Quetiapine (Seroquel) | – | 3 | 4-5 |
| ʻO Risperidone (Risperdal) | 4 | 2 | 2 |
ʻO Quetiapine ke kumu o ka loaʻa ʻana o ke kaumaha. ʻO kahi laʻana, i ke aʻo ʻana i nā keiki me kahi maʻi kaumaha o ka maʻi bipolar, ʻo ka poʻe i loaʻa ka quetiapine i loaʻa ma kahi o 3 paona ma mua o ka poʻe i loaʻa kahi placebo.
Nā pilikia puʻuwai a me ka maʻi diabetes
Hiki i kekahi mau lāʻau antypsychotic atypical ke hoʻonui i ka nui o ke kolukolika (LDL a me nā triglycerides). Hoʻohui ʻia, ʻo kēlā mau lāʻau lapaʻau - me ka ʻokoʻa o ka aripiprazole (Abilify) -e hiki ke hoʻonui i ke kō kō, a i ʻole nā kaha ʻē aʻe o ka maʻi kō, i kekahi mau keiki, a i ʻole e hoʻomāhuahua i ka kaohi kō kō no nā poʻe me ka maʻi kō.
ʻAʻole hiki ke ʻōlelo i ka nui o ka hoʻonui i ka makaʻu i hoʻohui ʻia i nā lāʻau, a i ʻole inā ʻoi aku ka maikaʻi o kekahi lāʻau ma mua o kekahi no nā keiki. Ma muli o nā noiʻi i paʻi ʻia, hiki i ka olanzapine (Zyprexa) ke hoʻonui i ka nui o nā kiʻekiʻe kolesterol i nā keiki ma mua o ka poʻe mākua.
ʻOiai he maʻamau nā hiʻohiʻona puʻuwai-puʻuwai (EKGs), hōʻike hoʻokahi kahi hoʻonui i ka manawa o ka puʻuwai me ka risperidone i loko o nā pule mua ʻelua o ka mālama ʻana. Ua hoʻi ka helu o ka puʻuwai o ka poʻe komo i ka maʻamau ma hope o ʻelua mau pule o ka mālama ʻana.
Ka hana Suicidal
I ke aʻo ʻana i nā keiki e lawe nei i nā antypsychotics atypical, aia kekahi mau mea i hōʻike i ka hana suicidal, akā ʻaʻole hiki ke haʻi inā he hoʻonui a hoʻemi paha kēia i ka hopena o ka hana suicidal, a ʻaʻohe hopena iki.
ʻO nā lāʻau Psychoactive, e like me kekahi antidepressants, ua loaʻa e hoʻonui i kēia pilikia i nā ʻōpio. Ma muli o ka ʻāpana ʻana o ka aripiprazole (Abilify) a me ka quetiapine (Seroquel) i kekahi o ka hana neurotransmitter like i loko o ka lolo e like me kēia mau antidepressants, lawe nā lāʻau i kahi ʻōlelo aʻoaʻo koʻikoʻi e hoʻonui paha lākou i ka pilikia o ka noʻonoʻo a me ka lawena suicidal, ʻoiai ʻaʻole maopopo ka hōʻike.
I nā mākua me schizophrenia, clozapine (Clozaril, Fazaclo ODT) ʻo ia wale nō ka lāʻau antypsychotic atypical i loaʻa e hōʻemi ai i ka makaʻu a me ka lawena suicidal. ʻAʻole i aʻo ʻia kēia i nā keiki.
Nā ʻaoʻao ʻē aʻe
Ua loaʻa nā haʻawina o risperidone (Risperdal) i nā helu haʻahaʻa o nā hopena ʻē aʻe, akā ma muli paha o nā haʻahaʻa haʻahaʻa i hoʻohana ʻia, a me ka ukali pōkole. ʻO nā neʻe a me nā neʻe o ke kino maʻamau (nā hōʻailona extrapyramidal), pinepine ʻole i nā hoʻokolohua wā pōkole, akā ua hōʻike pinepine ʻia lākou ma mua o nā mea maʻi e lawe ana i kahi placebo.
ʻIke ʻia ʻo Risperidone e hoʻonui i nā pae o ka hormone prolactin, kahi e kōkua ai i ka hana ʻana o ka waiū umauma ma hope o ka hāpai ʻana. I nā wahine hāpai ʻole a me nā kāne, hiki i ka hoʻonui ʻana i ka prolactin ke hopena i ka hoʻonui ʻana i nā umauma a me nā pilikia me ka hana moekolohe. Ua ʻike ʻia nā haʻawina o nā keiki ua piʻi aʻe ka risperidone i nā pae prolactin, akā ʻaʻohe mea i hōʻike ʻia i nā hōʻailona a i ʻole nā hōʻailona e like me ka hoʻonui ʻana o ka umauma. ʻAʻole maopopo inā, i ka hala ʻana o ka manawa, noho kiʻekiʻe nā pae prolactin a hoʻi i ka maʻamau.
ʻO nā hopena ʻē aʻe i ʻike pinepine ʻia me ka aripiprazole (Abilify) ma mua o kahi placebo me ka hiamoe, kahe ʻana, ka haʻalulu, ka nausea, a me ka luaʻi. ʻO nā neʻe ʻole o nā lima, nā wāwae, a me ke kino i ʻike pinepine ʻia i nā keiki e lawe ana i ka aripiprazole. Pono e aʻo hou e hoʻoholo inā hoʻoholo kēia mau hopena ʻaoʻao, noho paʻa, a hōʻino paha i ka manawa me ka hoʻomau hoʻomau ʻana.
I ke aʻo ʻana i ka hoʻohana ʻana o quetiapine (Seroquel) i ka mālama ʻana i nā ʻōpio me ka maʻi maʻi, ua kū ka 11 pākēneka o ka poʻe e lawe ana i ka lāʻau ma muli o ka akathisia, kahi ʻano kahi e hoʻomaha ai ke kanaka, me he mea lā ʻaʻole hiki iā lākou ke noho mālie. Inā ʻole, ua ʻae maikaʻi ʻia ka lāʻau.
ʻO nā hopena ʻē aʻe i hōʻike ʻia e nā keiki e lawe ana i ka olanzapine me ka sedation a me ka hoʻonui ʻana i ka makemake.
Ma ke ʻano holoʻokoʻa, hōʻike pinepine ʻia nā hopena ʻē aʻe me ka olanzapine (Zyprexa) ma mua o ka quetiapine (Seroquel) a i ʻole risperidone (Risperdal). Loaʻa pinepine ka ʻoʻoleʻa i nā maʻi i mālama ʻia me ka olanzapine i hoʻohālikelike ʻia me ka quetiapine, a ʻo ka luhi ka mea pinepine me ka olanzapine i hoʻohālikelike ʻia me risperidone. Akā ʻoi aku ka nui o nā mea maʻi e lawe ana i ka risperidone i hōʻike i kahi hopena pili e pili ana i ka neʻe i hoʻohālikelike ʻia me ka poʻe e lawe nei i ka olanzapine.
E hoʻi i luna E heluhelu houKoho i kahi Antypsychotic Atypical no nā Keiki
Ma muli o ke kino liʻiliʻi o nā hōʻike e pili ana i ka hoʻohana ʻana i nā antypsychotics atypical e nā keiki a me nā ʻōpio, paʻakikī e hoʻoholo i kā lākou hopena pōkole a me ka palekana. A ʻaʻohe mea i ʻike ʻia e pili ana i ko lākou palekana wā lōʻihi a me ka pono no ka mea ʻo nā haʻawina e pili ana i ka poʻe ʻōpio liʻiliʻi a liʻiliʻi i ka lōʻihi.
No laila ʻaʻole hiki iā mākou ke koho i kahi Best Buy atypical antipsychotic no ka hoʻohana ʻia e nā keiki a me nā ʻōpio me ka schizophrenia, ka maʻi bipolar, nā maʻi ulu hoʻomāhuahua, a me nā maʻi disruptive behavior. Ma kahi o ka mea, ua paipai nā kākā'ōlelo aʻoaʻo i nā mākua e kaupaona pono i nā pilikia a me nā pono. ʻO kahi hoʻolālā lapaʻau ākea no nā keiki me kēia mau maʻi e pono e hoʻopili i ka conductive behavioral therapy, ka hoʻomaʻamaʻa hoʻomalu makua a me nā papahana aʻo kūikawā, me nā lāʻau lapaʻau hiki ke loaʻa.
Ke hoʻoholo nei e hoʻohana i kekahi o kēia mau lāʻau lapaʻau, a inā pēlā, ʻo wai ia, e hana pū ʻia me ke kauka o kāu keiki a pono e hoʻokumu ʻia i nā manaʻo nui. ʻO kahi laʻana, he aha nā hōʻailona koʻikoʻi a koʻikoʻi loa o kāu keiki? ʻO kēia mau hōʻailona i loaʻa nā lāʻau antipsychotic e hoʻomaha? Kūpono a waiwai paha nā pōmaikaʻi iā ʻoe a me kāu keiki?
Pono ʻoe e noʻonoʻo i ke kumukūʻai o ka lāʻau, i nui paha ia. A nānā i nā hopena ʻino o ka lāʻau i ka mōʻaukala o ka moʻolelo olakino o kāu keiki e ʻike pono ia he kūpono. Ua aʻo kūpono ʻole ʻia kēia mau lāʻau i loko o nā keiki e pili ana i nā hopena ʻaoʻao, no laila pono ʻoe e noʻonoʻo pū i nā hōʻike mai ka hoʻopaʻa ʻana i nā mākua.
Inā loaʻa i kāu keiki kahi ʻano pilikino - e laʻa me ADHD a i ʻole kaumaha - e ʻike pono ʻoe e mālama ʻia kēia mau mea. Hiki paha i kēia ke hoʻomaikaʻi i nā hōʻailona o kāu keiki. No ka maʻi bipolar, aia kekahi, ʻoi aku ka maikaʻi o nā lāʻau i noiʻi ʻia, e like me ka lithium, divalproex, a me ka carbamazepine, pono e hoʻāʻo mua ʻia ma mua o ka noʻonoʻo ʻana i nā antypsychotics atypical.
Inā hoʻoholo ʻoe e hāʻawi i kāu keiki i kahi antipsychotic, ʻōlelo mākou e hoʻohana i ka lāʻau haahaa haʻahaʻa e hoʻoliʻiliʻi i ka hiki i nā hopena ʻaoʻao. A e nānā pono e loiloi hou ʻia kāu keiki e kekahi kauka e hoʻoholo inā he kōkua a pono paha ka lāʻau.
E hoʻi i luna E heluhelu houKamaʻilio me kāu Kauka
ʻAʻole pili ka ʻike a mākou e hōʻike ai ma aneʻi e lilo i mea pani no ka hoʻokolokolo a ka kauka. Akā lana ko mākou manaʻo e kōkua ia iā ʻoe a me kāu kauka o kāu keiki e hoʻoholo inā kūpono kahi antipsychotic.
E hoʻomanaʻo i ka nui o ka poʻe e makemake e kūkākūkā i ke kumukūʻai o ka lāʻau me kā lākou kauka, a ua ʻike ʻia nā noiʻi ʻaʻole mālama pinepine nā kauka i ke kumukūʻai i ka wā e kuhikuhi ana i ka lāʻau. Inā ʻaʻole ʻoe e lawe mai, e noʻonoʻo paha kāu kauka ʻaʻole ka kumu kūʻai nāu.
Manaʻo ka poʻe he nui (me nā kauka) ʻoi aku ka maikaʻi o nā lāʻau hou. ʻOiai he manaʻo kūlohelohe kēlā e hana ai, ʻaʻole ia he ʻoiaʻiʻo. ʻImi mau i nā noiʻi he nui nā lāʻau lapaʻau kahiko e like me-a i kekahi mau ʻoi aku ka maikaʻi ma mua o ka lāʻau hou. E noʻonoʻo iā lākou ma ke ʻano he "hoʻāʻo a ʻoiaʻiʻo hoʻi," kikoʻī ke hiki mai i kā lākou moʻolelo palekana. ʻAʻole i hālāwai hou nā lāʻau hou i ka hoʻāʻo o ka manawa, a hiki i nā pilikia i manaʻo ʻole ʻia ke hōʻiliʻili ke kū lākou i ka mākeke.
ʻOiaʻiʻo, ʻoi aku ka maikaʻi a me ka palekana o kekahi o nā lāʻau lapaʻau hou. E kamaʻilio me kāu kauka e pili ana i nā plus a me nā minus o nā mea hou vs. nā lāʻau kahiko, e like me nā lāʻau laulaha.
Hele nā lāʻau lapaʻau i "generic" ke hala nā palapala Sila o ka hui ma luna o lākou, ma hope o 12 a 15 mau makahiki paha. I kēlā manawa, hiki i nā ʻoihana ʻē aʻe ke hana a kūʻai aku i ka lāʻau.
ʻOi aku ka liʻiliʻi o nā kumukūʻai ma mua o nā lāʻau lapaʻau inoa hou, akā ʻaʻole ia he mau lāʻau liʻiliʻi. ʻOiaʻiʻo, ʻo ka hapa nui o nā generics e mau ana ka waiwai i mau makahiki ma hope o ka kūʻai mua ʻia ʻana. ʻO ia ke kumu i kākau ʻia ai ma mua o 60 pākēneka o nā kuhikuhi a pau i ka U.S. i kēia lā no nā generics.
ʻO kekahi pilikia nui e kamaʻilio e pili ana i kāu kauka e mālama nei i kahi moʻohelu o nā lāʻau āu e lawe nei. Nui nā kumu no kēia:
- ʻO ka mea mua, inā ʻike ʻoe i kekahi mau kauka, ʻaʻole paha kēlā me kēia e noʻonoʻo i ka lāʻau a ka poʻe ʻē aʻe i kuhikuhi ai.
- ʻO ka lua, no ka mea ʻokoʻa ka poʻe i kā lākou pane i ka lāʻau, he mea maʻamau no nā kauka i kēia lā e kuhikuhi i kekahi mau mea ma mua o ka loaʻa ʻana o kahi e hana maikaʻi a maikaʻi paha.
- ʻO ke kolu, he nui ka poʻe e lawe i nā lāʻau i kuhikuhi ʻia, nā lāʻau ʻaʻohe kuhikuhi, a me nā mea hoʻopiha papaʻai i ka manawa like. Hiki iā lākou ke launa i nā ala i hiki ke hōʻemi i ka pono āu e loaʻa ai mai ka lāʻau a weliweli paha.
- ʻO ka hope loa, ʻo nā inoa o nā lāʻau i kuhikuhi ʻia - he generic a me ka brand-paʻakikī paʻakikī e haʻi a hoʻomanaʻo.
No kēlā mau kumu āpau, he mea nui e mālama i kahi papa inoa i kākau ʻia o nā lāʻau āpau a me nā mea hoʻopihapiha āu e lawe nei, a e loiloi pinepine ia me kāu mau kauka.
A e maʻa mau e hoʻomaopopo ʻoe i ka mahele lāʻau o ka lāʻau e kuhikuhi ʻia ana nāu a me nā pila āu e manaʻo ai e lawe i kēlā me kēia lā. Pono kāu kauka e haʻi iā ʻoe i kēia ʻike. Ke hoʻopihapiha ʻoe i kahi kuhikuhi ma kahi kauka lāʻau a i ʻole inā loaʻa ia iā ʻoe ma ka leka uila, e nānā e ʻike i ka lāʻau a me ka helu o nā pila i kēlā me kēia lā ma ka ipu pill i kūlike i ka nui a kāu kauka i haʻi aku ai iā ʻoe.
E hoʻi i luna E heluhelu houPehea mākou e loiloi ai i nā Antipsychotics
Hoʻokumu nui ʻia kā mākou loiloi ma ka loiloi ʻepekema kūʻokoʻa o nā hōʻike e pili ana i ka pono, palekana, a me nā hopena maikaʻi ʻole o antipsychotics.Ua alakaʻi ʻia kahi kime o nā kauka a me nā mea noiʻi ma ka Oregon Health & Science University Evidence-Based Practice Center i ka hōʻuluʻulu manaʻo ʻana ma ke ʻano he ʻāpana o ka Project Review Effectiveness Drug, a i ʻole DERP. ʻO DERP kahi hana mua multi-state-of-its-kind e loiloi i ka hopena hoʻohālikelike a me ka palekana o nā haneli o nā lāʻau lapaʻau.
ʻO kahi synopsis o ka anamanaʻo DERP o antipsychotics ke kumu o kēia hōʻike. He kākāʻōlelo i Consumer Reports Best Buy Drugs kekahi lālā o ka hui noiʻi ma Oregon, ʻaʻohe ona kuleana kālā i kekahi ʻoihana lāʻau lapaʻau a huahana paha.
Loaʻa ka loiloi DERP piha o antipsychotics ma //derp.ohsu.edu/about/final-documentdisplay.cfm. (He palapala lōʻihi a loea kēia i kākau ʻia no nā kauka.)
Hōʻike ʻia nā ʻikepili a nā mea kūʻai mai Kūʻai Lāʻau maikaʻi loa i nā kikoʻī i nā ʻāpana o nā hana ma CRBestBuyDrugs.org.
E hoʻi i luna E heluhelu houKaʻana like i kēia hōʻike
Hiki ke hoʻoiho manuahi ʻia kēia hōʻike kope kope ʻia, paʻi hou ʻia, a hoʻolaha ʻia no ka hoʻohana ʻole ʻana i kēlā me kēia mea me ka ʻole o ka ʻae mai ka Consumer Reports & circledR; ʻoiai ke kumu e pili pono ana ia i nā Consumer Reports Best Buy Drugs. ™ Paipai mākou i ka hoʻolaha ākea no ka mea e hoʻomaopopo ai i nā mea kūʻai aku. Akā ʻaʻole ʻae ka Consumer Reports i ka hoʻohana ʻana i kona inoa a i ʻole nā mea hana no nā ʻoihana kalepa, kālepa, a me nā mea hoʻolaha. ʻO nā hui i makemake i ka hoʻolaha ākea o kēia hōʻike e pono e leka uila iā [email protected]. ʻO nā hōʻike mea kūʻai aku Best Buy Drugs ™ kahi waiwai kalepa o Consumers Union. Pono nā huaʻōlelo āpau e kuhikuhi i nā hōʻike mea kūʻai aku Best Buy Drugs ™ ma ke ʻano he kumu.
© 2012 Hui Pū ʻIa o U.S. U.S. Inc.
E hoʻi i luna E heluhelu houE pili ana iā mākou
Union Union, mea hoʻopuka o Consumer Reports & circledR; makasina, he hui kūʻokoʻa a me ka loaʻa kālā ʻole nona ka mikiona mai 1936 e hoʻolako i nā mea kūʻai aku me ka ʻike kaulike ʻole i nā waiwai a me nā lawelawe a hana i kahi mākeke kūpono. ʻO ia ka pūnaewele www.CRBestBuyDrugs.org. ʻO ConsumerReports.org ka pūnaewele o ka makasina.
ʻO kēia mau mea i hiki ke loaʻa i kahi hāʻawi mai ka Loio Kuhina Nui a me ka Polokalamu Hoʻolālā Hoʻolaha Prescriber, i kālā ʻia e kahi lehulehu o nā hoʻopiʻi hoʻopunipuni a nā mea kūʻai e pili ana i ka kūʻai aku ʻana i ka lāʻau lapaʻau Neurontin.
Hāʻawi ka Engelberg Foundation i kahi hāʻawi nui e kākoʻo kālā i ka hoʻokumu ʻana o ka papahana mai 2004 a 2007. ʻO nā kālā hou i loaʻa mai ka National Library of Medicine, kahi o nā National Institutes of Health. Aia kahi wehewehe kikoʻī no ka papahana ma CRBestBuyDrugs.org.
Ua ukali mākou i kahi hana hoʻoponopono koʻikoʻi e hōʻoia i ka ʻike o kēia hōʻike a ma ka Pūnaewele Pūnaewele ʻo Buy Best Drugs ka pololei a wehewehe i nā hana lapaʻau i ʻae ʻia. Inā ʻike mākou i kahi hemahema a i ʻole e makaʻala i hoʻokahi e hoʻoponopono mākou iā ia i ka hiki wawe. Akā ʻaʻole hiki i nā Consumer Reports a me nā mea kākau, nā hoʻoponopono, nā mea paʻi, nā laikini, a me nā mea hoʻolako ke kuleana no nā hemahema olakino a i ʻole nā hopena i lawe ʻia, a i ʻole nā hopena mai ka hoʻohana ʻana o ka ʻike ma kēia pūnaewele. E ʻoluʻolu e nānā i kā mākou ʻaelike hoʻohana ma CRBestBuyDrugs.org no ka ʻike hou aku.
ʻAʻole pono e ʻike ʻia nā hōʻike mea kūʻai mai nā lāʻau kūʻai maikaʻi loa e like me kahi pani no ke kūkā kūkākūkā ʻana me kahi kauka a olakino olakino. Hāʻawi ʻia kēia hōʻike a me ka ʻike ma CRBestBuyDrugs.org e hoʻomaikaʻi i ke kamaʻilio me kāu kauka ma mua o ke kuapo.
E hoʻi i luna E heluhelu houNā kūmole
- Nā polokalamu J, Winkler J, Jandrisevits MD, Apps J, Winkler J, Jandrisevits MD. Nā maʻi Bipolar: nā hōʻailona a me ka mālama ʻana i nā keiki a me nā ʻōpio. Kahuhipa Pediatr. 2008; 34 (1): 84-8.
- ʻO Arango C, Robles O, Parellada M, Fraguas D, Ruiz-Sancho A, Medina O, Zabala A, Bombin I, Moreno D. Olanzapine i hoʻohālikelike ʻia me ka quetiapine i nā ʻōpio me kahi ʻaoʻao psychotic mua. Eur Psychiatry ʻōpio ʻōpio. 2009; 18 (7): 418-28.
- ʻO Barzman DH, ʻo DelBello MP, ʻo Adler CM, ʻo Stanford KE, ʻo Strakowski SM. ʻO ka pono a me ka hoʻomanawanui ʻana i ka quetiapine me ka divalproex no ka mālama ʻana i ka impulsivity a me ka hōʻeuʻeu hōʻeuʻeu i nā ʻōpio me ka maʻi bipolar e hui pū ʻia a me nā maʻi disruptive behavior (s). Ka Nūpepa o ke keiki a me nā ʻōpio Psychopharmacology. 2006; 16 (6): 665-70.
- Nā kikowaena no ka mālama ʻana i ka maʻi. ʻO ka prevalence o Autism Spectrum Disorder-Autism a me nā Developmental Disability Monitoring Network, United States, 2006. MMWR. 2009; 58 (SS10): 1-20.
- ʻO Correll CU, Manu P, Olshanskiy V, Napolitano B, Kane JM, Malhotra AK. Ka pilikia Cardiometabolic o ka hanauna antipsychotic hanauna hou i ka wā hoʻohana mua i nā keiki a me nā ʻōpio. Ka Nupepa o ka ʻAmelika ʻAmelika Hui Pū ʻIa. 28 ʻOkakopa 2009. 302 (16): 1765-1773.
- Cummings CM, Fristad MA, Cummings CM, Fristad MA. Ka maʻi bipolar pēpē: ʻIke i ka mālama mua ʻana. ʻO Curr Opin Pediatr. 2008; 20 (5): 560-5.
- Loaʻa iā RI, McNamara NK, Branicky LA, Schluchter MD, Lemon E, Blumer JL. Ke aʻo pilote makapō makapō makapō ʻelua o risperidone i ka mālama ʻana i nā maʻi maʻi. Puka o ka American Academy of Child & Adolescent Psychiatry. 2000; 39 (4): 509-16.
- ʻO Findling RL, Nyilas M, Forbes RA, McQuade RD, Jin N, Iwamoto T, Ivanova S, Carson WH, Chang K. Hoʻomaʻamaʻa koʻikoʻi ʻana i ka maʻi bipolar I pediatric, manic a i ʻole episode i hui ʻia, me ka aripiprazole hoʻopaʻa haʻawina placebo. Ka Nūpepa o ka Psychiatry Clinical. 2009; 70 (10): 1441-51.
- ʻO Goldstein BI. Ka maʻi bipolar pēpē: ʻOi aku i kahi pilikia huhū. Pediatrics. 2010; 125 (6): 1283-5.
- Haas M, Delbello MP, Pandina G, Kushner S, Van Hove I, Augustyns I, Quiroz J, Kusumakar V. Risperidone no ka mālama ʻana i ka mania koʻikoʻi i nā keiki a me nā ʻōpio me ka maʻi bipolar: A randomized, double-blind, placebo-kontrol hoʻopaʻa haʻawina. Nā maʻi Bipolar. 2009; 11 (7): 687-700.
- Hazell P, Williams R, Hazell P, Williams R. Hōʻike hoʻoponopono: Hoʻololi i nā ʻike e pili ana i ka maʻi ʻōpio bipolar a me nā maʻi ulu ulu ākea. ʻO Curr Opin Psychiatry. 2008; 21 (4): 328-31.
- Luby J, Mrakotsky C, Stalets MM, Belden A, Heffelfinger A, Williams M, Spitznagel E. Risperidone i nā keiki kamaliʻi me nā maʻi autistic spectrum: kahi noiʻi no ka palekana a me ka pono. Ka Nūpepa o ke keiki a me nā ʻōpio Psychopharmacology. 2006; 16 (5): 575-87.
- Maglione M, et al. Hoʻohana-Label Hoʻohana o Atypical Antipsychotics: He Hoʻohou. Manaʻo Hoʻohālikelike Hoʻohālikelike Helu 43. (Hoʻomākaukau ʻia e ka ʻO Kaleponi Hema / RAND Hōʻike Manaʻo Hoʻohālikelike Ma lalo o ka ʻAelike No. HHSA290-2007-10062-1.) AHRQ Publication No. 11- EHC087-EF. Rockville, MD: ʻOihana no ka ʻimi noiʻi ola kino a me ka maikaʻi. Kepakemapa 2011.
- Marcus RN, Owen R, Kamen l, Manos G, McQuade RD, Carson WH, Aman MG. ʻO kahi placebo-kāohi ʻia, hoʻopaʻa ʻia o ka aripiprazole i nā keiki a me nā ʻōpio me ka huhū e pili ana i ka maʻi autistic. Ka Nūpepa o ka American Academy of Child & Adolescent Psychiatry. 2009; 48 (11): 1110-9.
- McCracken JT, et al. ʻO Risperidone i nā keiki me ka autism a me nā pilikia koʻikoʻi koʻikoʻi. Ka Nūpepa Lapaʻau ʻo New England. 2002; 347 (5): 314-21.
- National Institute of Mental Health. ʻO ka maʻi Bipolar i waena o nā keiki. Loaʻa ma nimh.nih.gov/ helu helu / 1bipolar_child.shtml. Loaʻa iā Malaki 10, 20011.
- National Institute of Mental Health. Schizophrenia. Loaʻa ma nimh.nih.gov/statistics/ 1SCHIZ.shtml. Loaʻa iā Malaki 10, 20011.
- Nā Pūnaewele ʻImi ma Pediatric Psychopharmacology Autism Network. Ka mālama Risperidone o ka maʻi autistic: Nā pōmaikaʻi ʻoi aku ka lōʻihi a me ka hoʻopau makapō ma hope o 6 mau mahina. Ka NūpepaʻAmelika o ka Psychiatry. 2005; 162 (7): 1361-9.
- ʻO Seeman P. Atypical antipsychotics: Ka hana o ka hana. Hiki iā J Psychiatry. 2002 Pepeluali; 47 (1): 27-38.
- Snyder R, Turgay A, Aman M, Binder C, Fisman S, Carroll A. Nā hopena o ka risperidone i ka hana a me nā maʻi disruptive i nā keiki me nā IQ subaverage. Ka Nūpepa o ka American Academy of Child & Adolescent Psychiatry. 2002; 41 (9): 1026-36.
Kahakaha: Inā loaʻa ka pahu kumukūʻai a , e kuhikuhi ana i ka mahele o kēlā lāʻau hiki ke loaʻa no ka uku haʻahaʻa o ka mahina ma o nā papahana hoʻēmi i hāʻawi ʻia e nā hale kūʻai nui. ʻO kahi laʻana, hāʻawi ʻo Kroger, Sam's Club, Target, a me Walmart i hoʻokahi mahina no ka loaʻa ʻana o nā lāʻau lapaʻau generic i koho ʻia no $ 4 a i ʻole he ʻekolu mau mahina no $ 10. ʻO nā hale kūʻai kaulahao ʻē aʻe, e like me Costco, CVS, Kmart, a me Walgreens, hāʻawi i nā papahana like. Loaʻa i kekahi mau papahana i nā kapu a i nā uku lālā, no laila e nānā pono i nā kikoʻī no nā kapu a e hōʻoia i ka uhi ʻia o kāu lāʻau.
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Hoihoi
Wahi a Demi Lovato e hana ana i kāna olakino noʻonoʻo i kōkua iā ia e lilo i Ally maikaʻi i ke kaiāulu ʻeleʻele