Nā Huahana Hoʻohui no ke kaumaha

Anter

• Ke kuleana o nā lāʻau
• Nā Antidepressants Atypical
• Nā Antipsychotics
• L-Triiodothyronine
• Nā mea hoʻonāukiuki
• Hoʻohui Hoʻohui e like me ka lapaʻau mua-laina

Inā loaʻa ʻoe i kahi maʻi depressive nui (MDD), ke lawe nei paha ʻoe i hoʻokahi antidepressant. ʻO ka hoʻohui ʻana i ka lāʻau lapaʻau kahi ʻano lapaʻau e hoʻohana nui nei nā kauka a me nā psychiatrist i loko o nā makahiki he 10 i hala.

Ke kuleana o nā lāʻau

A hiki i kēia manawa, ua kau nā kauka i kahi lāʻau lāʻau antidepressant mai kahi papa lāʻau wale nō, hoʻokahi i ka manawa hoʻokahi. Kapa ʻia kēia he monotherapy. Inā holo ʻole kēlā lāʻau, hoʻāʻo paha lākou i kahi lāʻau ʻē aʻe i loko o kēlā papa, a i ʻole hoʻololi i kekahi papa antidepressants āpau.

Hōʻike ka noiʻi i kēia manawa ʻo ka lawe ʻana i nā antidepressants mai nā papa he nui ke ala ʻoi loa e mālama ai iā MDD. Ua ʻike ʻia hoʻokahi noi ʻana e hoʻohana ana i kahi ala hoʻohui i ka hōʻailona mua o MDD e pāpālua paha i ka likelike o ke kala.

Nā Antidepressants Atypical

Ma kāna iho ponoʻī, maikaʻi loa ka bupropion i ka mālama ʻana iā MDD, akā hoʻohana ʻia ʻia pū paha me nā lāʻau ʻē aʻe i loko o ke kaumaha kaumaha. ʻO ka ʻoiaʻiʻo, ʻo ka bupropion kekahi o nā lāʻau lapaʻau hoʻohuihui i hoʻohana pinepine ʻia. Hoʻohana pinepine ʻia me nā mea hōʻemi e loaʻa hou i nā serotonin reuptake (SSRI) a me nā serotonin- norepinephrine reuptake inhibitors (SNRIs). ʻAno maikaʻi ʻia i ka poʻe i ʻike i nā hopena ʻino loa mai nā lāʻau antidepressant ʻē aʻe. Hiki iā ia ke hōʻoluʻolu i kekahi o nā hopena pili kolohe (hoʻoliʻiliʻi libido, anorgasmia) e pili pū me nā SSRI kaulana a me SNRI.

No ka poʻe e ʻike nei i ka nalo o ka makemake ʻole a me ka hiamoe ʻole, he koho paha ka mirtazapine. ʻO nā hopena ʻaoʻao maʻamau ka loaʻa ʻana o ke kaumaha a me ka hoʻohiamoe. Eia naʻe, ʻaʻole i aʻo ʻia ʻo mirtazapine i kahi hohonu e like me kahi lāʻau hoʻohui.

Nā Antipsychotics

Hōʻike ka noiʻi e loaʻa paha kekahi pōmaikaʻi i ka mālama ʻana i nā ʻōuli koena i ka poʻe e lawe ana iā SSRI me nā antypsychotics atypical, e like me aripiprazole. ʻO nā hopena ʻē aʻe e pili ana i kēia mau lāʻau, e like me ka loaʻa ʻana o ke kaupaona, haʻalulu nā mākala, a me nā haunaele metabolic, pono e noʻonoʻo pono ʻia no ka mea e hoʻolōʻihi a hoʻomāhuahua paha i kekahi mau hōʻailona o ke kaumaha.

L-Triiodothyronine

Hoʻohana kekahi mau kauka iā L-Triiodothyronine (T3) i ka hoʻohui ʻia me ka tricyclic antidepressants (TCAs) a me nā monoamine oxidase (MAOI). ʻOi aku ka maikaʻi o nā manaʻo noiʻi ʻo T3 i ka wikiwiki i ka pane o ke kino i ka mālama ʻana ma mua o ka hoʻonui ʻana i ka likelike e komo ke kanaka i ke kala.

Nā mea hoʻonāukiuki

ʻO D-amphetamine (Dexedrine) a me methylphenidate (Ritalin) nā mea hoʻonāukiuki i hoʻohana ʻia e mālama i ke kaumaha. Hiki iā lākou ke hoʻohana ʻia ma ke ʻano he monotherapy, akā hiki paha ke hoʻohana ʻia i kahi hui pū me nā lāʻau antidepressant. Kōkua nui lākou inā he hopena wikiwiki ka hopena i makemake ʻia. ʻO nā mea maʻi i nāwaliwali, a i ʻole nā ​​mea maʻi komorbid (e like me ka hahau ʻana) a i ʻole nā ​​maʻi olakino mau, he moho maikaʻi paha lākou no kēia hui pū ʻana.

Hoʻohui Hoʻohui e like me ka lapaʻau mua-laina

Haʻahaʻa ka helu kūleʻa o ka mālama ʻana i ka monotherapy, a no laila he nui nā kānaka noiʻi a me nā kauka e manaʻoʻiʻo nei i ke ala mua a me ka maikaʻi loa no ka mālama ʻana iā MDD he mau lapaʻau hui pū ʻia. Eia nō naʻe, hoʻomaka nā kauka he nui me ka lāʻau antidepressant hoʻokahi.

Ma mua o ka hoʻoholo ʻana e pili ana i ka lāʻau, hāʻawi i ka manawa e hana. Ma hope o kahi manawa hoʻokolokolo (maʻamau ma kahi o 2 a 4 mau pule), inā ʻaʻole ʻoe e hōʻike i kahi pane kūpono, makemake paha kāu kauka e hoʻololi i nā lāʻau a hoʻohui i kahi lāʻau hou e ʻike ai inā kōkua ka hoʻohui i kāu hoʻolālā lapaʻau.