Hiki iā ʻoe ke overdose ma nā Antidepressants?

Anter

• He aha nā ʻano maʻamau i kau ʻia a make?
• TCAs
• SSRIs
• SNRIs
• MAOI
• Kāohi ʻana i ke ola
  
• He aha nā hōʻailona a me nā ʻōuli o ka overdose?
• Nā ʻōuli akahai
• Nā ʻōuli koʻikoʻi
• Serotonin maʻi maʻi
• Nā hopena ʻaoʻao antidepressant maʻamau
• He aha e hana ai inā manaʻo ʻoe he overdose
• Pehea e mālama ʻia ai ka overdose?
• Ke laina lalo

Hiki paha ke overdose?

ʻAe, hiki i ka overdose ma kēlā me kēia ʻano antidepressant, keu hoʻi inā lawe ʻia me nā lāʻau ʻē aʻe a i ʻole nā ​​lāʻau.

ʻO nā Antidepressants nā lāʻau lapaʻau i hoʻohana ʻia e mālama ai i nā ʻōuli o ke kaumaha, ka ʻeha mau, a me nā maʻi ʻano ʻē aʻe. ʻLelo ʻia lākou e hana e ka hoʻonui ʻana i nā pae o kekahi mau kemika - serotonin a me dopamine - i ka lolo.

Loaʻa nā ʻano antidepressants he nui, e like me:

• antidepressants tricyclic (TCAs), e like me amitriptyline a me imipramine (Tofranil)
• nā mea hoʻopaneʻe monoamine oxidase (MAOI), e like me isocarboxazid (Marplan) a me phenelzine (Nardil)
• ʻoki nā serotonin reuptake inhibitors(SSRIs), me fluoxetine (Prozac), sertraline (Zoloft), a me escitalopram (Lexapro)
• ʻo ka serotonin-norepinephrine hoʻi i nā mea kāohi(SNRIs), e like me duloxetine (Cymbalta) a me venlafaxine (Effexor XR)
• nā lāʻau lapaʻau atypical, me bupropion (Wellbutrin) a me vortioxetine (Trintellix)

Ua hōʻike ʻia nā overdoses TCA i nā hopena make ma mua o MAOI, SSRI, a i ʻole SNRI.

He aha nā ʻano maʻamau i kau ʻia a make?

ʻO ka hopena make o kahi antidepressant hilinaʻi ʻia i nā kumu he nui, e like me:

• ke ʻano o ka antidepressant
• pehea e hoʻopili ai kou kino i ka lāʻau
• kou kaumaha
• kou mau makahiki
• inā loaʻa iā ʻoe nā kūlana preexisting, e like me ka naʻau, ka puʻuwai, a me ke ʻano ate
• inā ʻoe i lawe i ka antidepressant me ka waiʻona a i ʻole nā ​​lāʻau ʻē aʻe (e like me nā antidepressants ʻē aʻe)

TCAs

Ke hoʻohālikelike ʻia i nā ʻano antidepressants ʻē aʻe, hopena nā tricyclic antidepressants (TCA) i ka helu kiʻekiʻe loa o nā overdosis make.

ʻO ka mahele maʻamau o ka TCA amitriptyline ma waena o 40 a me 100 milligrams (mg). ʻO ka mahele maʻamau o ka imipramine ma waena o 75 a me 150 mg i kēlā me kēia lā. Wahi a hoʻokahi hōʻike 2007 o ka ʻikepili kikowaena o U.S., ʻike pinepine ʻia nā ʻōuli hoʻoweliweli me nā lāʻau i ʻoi aku ma mua o 1,000 mg. I hoʻokahi hoʻokolohua hoʻokolohua, ʻo 200 mg wale nō ka hopena make o ka imipramine.

Ua paipai nā kānaka noiʻi i ka lāʻau pōpilikia no kēlā me kēia mea i lawe i ka lāʻau o desipramine, nortriptyline, a i ʻole trimipramine ʻoi aku ma mua o 2.5 mg i kēlā me kēia kilokilo (kg) o ke kaupaona. No ke kanaka kaupaona 70 kg (ma kahi o 154 paona), unuhi ʻia kēia ma kahi o 175 mg. No nā TCA ʻē aʻe, paipai ʻia ka mālama ulia pōpilikia no nā kaha i ʻoi aku ma mua o 5 mg / kg. No ke kanaka kaupaona 70 kg, unuhi kēia i kahi o 350 mg.

SSRIs

ʻO nā mea hoʻohiehie serotonin reuptake (SSRIs) nā antidepressants i kuhikuhi pinepine ʻia no ka mea loaʻa iā lākou ka liʻiliʻi o nā hopena. Inā lawe hoʻokahi ʻia, ʻaʻohe mea make ka overdose SSRI.

ʻO ka mahele maʻamau o ka SSRI fluoxetine (Prozac) ma waena o 20 a 80 mg i kēlā me kēia lā. ʻO kahi mahele haʻahaʻa ma lalo o 520 mg o fluoxetine i hoʻopili ʻia me kahi hopena make, akā aia kekahi e lawe ana i 8 gram o fluoxetine a ola hou.

ʻOi aku ka kiʻekiʻe o ka makaʻi a me ka make ke lawe ʻia kahi lāʻau kiʻekiʻe o kahi SSRI me ka wai ʻona a i ʻole nā ​​lāʻau ʻē aʻe.

SNRIs

Serotonin-norepinephrine reuptake inhibitors (SNRI) i manaʻo ʻia he mea ʻawahia ma mua o TCAs, akā ʻoi aku ka ʻona ma mua o SSRIs.

ʻO kahi mahele maʻamau o ka SNRI venlafaxine ma waena o 75 a me 225 mg i kēlā me kēia lā, lawe ʻia i ʻelua a ʻekolu paha mau mahele i hoʻokaʻawale ʻia. Ua ʻike ʻia nā hopena make ma nā hāmeʻa ma lalo o 2,000 mg (2 g).

Eia nō naʻe, ʻaʻole make ka hapa nui o nā overdosis SNRI, ʻoi aku ma nā koina kiʻekiʻe. ʻO ka nui o nā hihia o nā overdosis make e hoʻopili i nā lāʻau ʻoi aku ma mua o hoʻokahi.

MAOI

Monoamine oxidase inhibitors (MAOI) kahi papa kahiko o nā antidepressants a ʻaʻole hoʻohana ʻia e like me ka laulā. ʻO ka hapa nui o nā hihia MAOI hiki ke lawe ʻia nā lāʻau nui me ka wai ʻona a i ʻole nā ​​lāʻau ʻē aʻe.

Hiki i nā ʻōuli koʻikoʻi o kahi overdose ke hana inā lawe ʻoe i nā mea ʻoi aku ma mua o kou kaumaha o ke kino. Ka make mai kahi MAOI overdose, akā ʻo kēia no ka mea ʻaʻole lākou i kuhikuhi nui ʻia ma muli o kā lākou launa pū ʻana.

Kāohi ʻana i ke ola

1. Inā manaʻo ʻoe aia kekahi i ka makaʻu koke iā ia iho a hōʻeha paha i kekahi.
2. • Kāhea iā 911 a i ʻole kāu helu kūloko kūloko.
3. • Noho me ke kanaka a hiki i ke kōkua ʻana.
4. • Wehe i nā pū, nā pahi, nā lāʻau, a i ʻole nā ​​mea ʻē aʻe e hoʻopōʻino.
5. • E hoʻolohe, akā, mai hoʻokolokolo, hoʻopaʻapaʻa, hoʻoweliweli, a ʻū paha.
6. Inā ʻoe a i ʻole kekahi mea āu e ʻike nei e noʻonoʻo nei i ka pepehi kanaka, e loaʻa i ke kōkua mai kahi pilikia a i ʻole ka laina pale pale hoʻomake. E hoʻāʻo i ka National Suicide Prevent Lifeline ma 800-273-8255.

He aha nā hōʻailona a me nā ʻōuli o ka overdose?

Hiki i ka overdosing ma nā antidepressants ke hoʻonāukiuki i nā ʻōuli koʻikoʻi. I kekahi mau hihia, hiki i ka make ke hiki.

E pili kāu mau ʻōuli pākahi i:

• ehia nā lāʻau i lawe ʻia
• pehea kou noʻonoʻo i ka lāʻau
• inā ʻoe i lawe i ka lāʻau i hui pū ʻia me nā lāʻau ʻē aʻe

Nā ʻōuli akahai

I nā hihia maʻalahi, ʻike paha ʻoe:

• dilated pupils
• huikau
• ʻeha poʻo
• hiamoe
• waha maloo
• fiva
• ʻike hihi ʻole
• kahe koko kiʻekiʻe
• nausea a me ka luaʻi

Nā ʻōuli koʻikoʻi

I nā hihia koʻikoʻi, ʻike paha ʻoe:

• nā ʻōlelo hoʻohiwahiwa
• ka wikiwiki o ka puʻuwai wikiwiki (tachycardia)
• ka hopu ʻana
• haʻalulu
• haʻahaʻa puʻe (hypotension)
• koma
• hopu naʻau
• kaumaha hanu
• make

Serotonin maʻi maʻi

ʻO ka poʻe i overdose ma nā antidepressants e ʻike pū i ka maʻi serotonin. ʻO ka maʻi Serotonin kahi hopena lāʻau lapaʻau maikaʻi ʻole i kū ʻia ke kūkulu ʻia ka serotonin he nui i kou kino.

Hiki i ka maʻi Serotonin ke kumu:

• nausea
• ka luaʻi
• pāhoehoe
• ʻōpū o ka ʻōpū
• huikau
• hopohopo
• kuʻi ka naʻau kaulike (arrhythmia)
• loli i ke kaomi koko
• haʻalulu
• koma
• make

Nā hopena ʻaoʻao antidepressant maʻamau

E like me ka hapa nui o nā lāʻau, hiki i nā antidepressants ke kumu i nā hopena ʻoluʻolu a hiki i kahi lāʻau haʻahaʻa. ʻO nā hopena ʻaoʻao maʻamau e pili pū me:

• ʻeha poʻo
• hopohopo
• pāhoehoe
• nalo ʻai ʻole
• pilikia hiamoe
• waha maloo
• kōpaʻa
• loaʻa kaupaona
• ʻūpā
• kaʻa hoʻohaʻahaʻa haʻahaʻa

ʻAʻole ʻoluʻolu nā ʻaoʻao i ka wā mua, akā hoʻomaikaʻi mau lākou me ka manawa. Inā ʻoe e ʻike i kēia mau hopena ʻaoʻao i ka lawe ʻana i kāu lāʻau i kauoha ʻia, ʻaʻole ia he manaʻo ua overdosed ʻoe.

Akā pono ʻoe e haʻi i kāu kauka e pili ana i nā hopena ʻē aʻe āu e ʻike nei. Kaukaʻi ʻia i kāu koʻikoʻi o ka hōʻailona, ​​makemake paha kāu kauka e hōʻemi i kāu mea hana a hoʻololi iā ʻoe i kahi lāʻau ʻokoʻa.

He aha e hana ai inā manaʻo ʻoe he overdose

Inā manaʻo ʻoe ua kupu mai kekahi lāʻau nui, e ʻimi koke i ka mālama olakino. ʻAʻole ʻoe e kali a hiki i ka hōʻeha ʻana o kāu mau ʻōuli. ʻO kekahi ʻano antidepressants, keu hoʻi ʻo MAOI, ʻaʻole paha e hoʻokumu i nā ʻōuli koʻikoʻi a hiki i 24 mau hola ma hope o ka hoʻonui ʻana.

Ma ʻAmelika Hui Pū ʻIa, hiki iā ʻoe ke hoʻokaʻaʻike i ka National Capital Poison Center ma 1-800-222-1222 a kali i nā ʻōkuhi ʻē aʻe.

Inā kūpilikiʻi nā ʻōuli, e kāhea i kāu lawelawe kūloko kūloko. E hoʻāʻo e noho mālie a hoʻomaʻalili i kou kino ʻoiai ʻoe e kali nei no ka hōʻea ʻana mai o nā limahana pilikia.

Pehea e mālama ʻia ai ka overdose?

I ka hihia o kahi overdose, e lawe nā limahana pilikia i ka haukapila a i ʻole ke keʻena pilikia.

Hāʻawi ʻia paha iā ʻoe ka nānahu lanahu ke hele nei ʻoe. Hiki i kēia ke kōkua e omo i ka lāʻau a hōʻemi i kekahi o kāu mau ʻōuli.

Ke hōʻea ʻoe i ka haukapila a i ʻole kahi lumi pilikia, hiki i kāu kauka ke pume i kou ʻōpū e hemo i nā lāʻau i koe. Inā hoʻonāukiuki a hyperactive paha ʻoe, hoʻohana paha lākou i nā benzodiazepines e hoʻowalewale iā ʻoe.

Inā ʻoe e hōʻike nei i nā ʻōuli o ka maʻi serotonin, hiki paha iā lākou ke lawelawe i ka lāʻau e ālai ai i ka serotonin. Pono pono nā wai kūmomo (IV) e hoʻopiha i nā meaola kūpono a pale i ka make wai.

Ke pau kāu mau hōʻailona, ​​koi ʻia ʻoe e noho i ka haukapila no ka nānā ʻana.

Ke laina lalo

Ke hala ka lāʻau i waho o kāu ʻōnaehana, e hoʻōla loa paha ʻoe.

Pono e lawe i nā antidepressants ma lalo o ka nānā ʻana a ka lāʻau. ʻAʻole pono ʻoe e lawe i nā mea hou aʻe ma mua o kāu lāʻau i kauoha ʻia, a ʻaʻole pono ʻoe e hoʻoponopono i kēia lāʻau me ka ʻole o ka ʻae a kāu kauka.

ʻO ka hoʻohana ʻana i nā lāʻau antidepressants me ka ʻole o kauka a i ʻole ke kāwili ʻana iā lākou me nā lāʻau ʻē aʻe hiki ke makaʻu loa. ʻAʻole hiki iā ʻoe ke hilinaʻi pehea e launa pū ai me kāu kemika o kēlā me kēia kino a i ʻole nā ​​lāʻau a lāʻau ʻē aʻe āu e lawe nei.

Inā koho ʻoe e hoʻohana i nā antidepressants leʻaleʻa a kāwili iā lākou me nā mea leʻaleʻa ʻē aʻe, e hoʻomaopopo i kāu kauka. Hiki iā lākou ke kōkua iā ʻoe e hoʻomaopopo i kāu pilikino o ka launa ʻana a me ka overdose, a me ke kiaʻi no nā loli i kou olakino holoʻokoʻa.