Mea Kākau: Judy Howell
Lā O Ka Hana: 4 Iulai 2021
HōʻAno Hou I Ka Lā: 18 Nowemapa 2024
Anonim
Efavirenz, Emtricitabine and Tenofovir Treat HIV and AIDs in Adults - Overview
Wikiō: Efavirenz, Emtricitabine and Tenofovir Treat HIV and AIDs in Adults - Overview

Anter

He aha ʻo Atripla?

ʻO Atripla kahi lāʻau lapaʻau inoa inoa e hoʻohana ʻia e mālama i ka maʻi HIV i nā mākua a me nā keiki. Kau ʻia no ka poʻe i kaupaona ma ka liʻiliʻi 88 mau paona (40 kilokilo).

Hiki ke hoʻohana wale ʻia ʻo Atripla ma ke ʻano he regimen lapaʻau piha (hoʻolālā). Hiki nō ke hoʻohana pū ʻia me nā lāʻau ʻē aʻe. Hele mai ia ma ke ʻano he papa hoʻokahi i loaʻa nā lāʻau ʻekolu:

  • efavirenz (600 mg), ʻo ia kahi mea non-nucleoside reverse transcriptase inhibitor (NNRTI)
  • tenofovir disoproxil fumarate (300 mg), ʻo ia kahi mea hoʻohālikelike nucleoside analog huli transcriptase (NRTI)
  • emtricitabine (200 mg), ʻo ia pū kekahi me ka nucleoside analog huli hoʻohuli transcriptase (NRTI)

ʻAʻole hōʻike nā alakaʻi i kēia manawa iā Atripla ma ke ʻano he koho mua loa no ka hapanui o nā poʻe me ka maʻi HIV. ʻO kēia no ka mea aia kekahi mau hoʻoponopono hou e ʻoi aku ka palekana a ʻoi paha ka maikaʻi no ka hapanui o ka poʻe. Eia nō naʻe, kūpono paha ʻo Atripla no kekahi poʻe. E hoʻoholo kāu kauka i ka lāʻau maikaʻi loa nāu.

He mea nui e hoʻomaopopo ʻaʻole i ʻae ʻia ʻo Atripla e pale aku i ka maʻi HIV.


ʻO Generator Atripla

Loaʻa ʻo Atripla ma ke ʻano he lāʻau inoa inoa inoa. ʻAʻole i loaʻa i kēia manawa i ka palapala generic.

Loaʻa i loko o Atripla ʻekolu mau mea hana lāʻau: efavirenz, emtricitabine, a me tenofovir disoproxil fumarate. Loaʻa kēlā me kēia o nā lāʻau i kēlā me kēia. Aia paha he mau hui ʻē aʻe o kēia mau lāʻau i loaʻa ma ke ʻano he generics.

Nā hopena ʻaoʻao Atripla

Hiki i ka Atripla ke hana i nā hopena ʻoluʻolu a koʻikoʻi paha. Loaʻa i ka papa inoa aʻe kekahi o nā hopena ʻaoʻao nui i hiki ke hana ʻia i ka lawe ʻana iā Atripla. ʻAʻole pili kēia papa inoa i nā hopena ʻē aʻe āpau.

No ka ʻike hou aku e pili ana i nā hopena ʻē aʻe o Atripla, a i ʻole nā ​​ʻōlelo aʻoaʻo e pili ana i ka hopena o ka hopena pilikia, e kamaʻilio me kāu kauka a kauka paha.

Nā hopena ʻaoʻao hou aʻe

Hiki i nā hopena ʻaoʻao maʻamau o Atripla ke hoʻopili:

  • pāhoehoe
  • nausea
  • ʻeha poʻo
  • ikehu haʻahaʻa
  • moeʻuhane ʻino
  • pilikia pilikia
  • ʻūpā
  • pilikia hiamoe
  • kaumaha
  • ʻehu a ʻili ʻili paha
  • māhuahua kolesterol

ʻO ka hapa nui o nā hopena ʻē aʻe i kēia papa inoa nā hopena akahai i ke kūlohelohe. Inā ʻoi aku ke koʻikoʻi a paʻakikī paha i ka mālama ʻana i kāu lāʻau, e kamaʻilio me kāu kauka a kauka paha.


Nā hopena hopena koʻikoʻi

ʻAʻole maʻamau nā hopena koʻikoʻi mai Atripla, akā hiki iā lākou ke hana. Kāhea koke i kāu kauka inā loaʻa nā hopena koʻikoʻi. Kāhea iā 911 inā manaʻo kou mau ʻōuli i ka hoʻoweliweli o ke ola a i ʻole inā manaʻo ʻoe e loaʻa ana kahi pilikia olakino.

Hiki i nā hopena ʻē aʻe a me kā lākou mau hōʻailona ke hoʻohui i kēia:

  • ʻOi aku ka maikaʻi o ka maʻi hepatitis B (HBV). Hiki i nā ʻōuli ke hoʻohui pū:
    • luhi
    • mimi ʻeleʻele
    • ʻeha o ke kino a nāwaliwali hoʻi
    • melemele o kou ʻili a keʻokeʻo o kou mau maka
  • Rash. Kū pinepine kēia hopena ʻaoʻao ma waena o 2 mau pule o ka hoʻomaka ʻana iā Atripla a hele wale i loko o hoʻokahi mahina. Hiki i nā ʻōuli ke hoʻohui pū:
    • ʻulaʻula, ʻili ʻili
    • puʻupuʻu i ka ʻili
  • Poino ke ake. Hiki i nā ʻōuli ke hoʻohui pū:
    • melemele o kou ʻili a keʻokeʻo o kou mau maka
    • ʻeha ma ka ʻaoʻao ʻākau i luna o kou ʻōpū (ʻōpū ʻōpū)
    • nausea a me ka luaʻi
  • Hoʻololi ke ʻano. Hiki i nā ʻōuli ke hoʻohui pū:
    • kaumaha
    • manaʻo suicidal
    • hana hoʻomāinoino
    • hopena paranoid
  • Nā pilikia ʻōnaehana hopohopo. Hiki i nā ʻōuli ke hoʻohui pū:
    • nā ʻōlelo hoʻohiwahiwa
  • Poino hakuʻala. Hiki i nā ʻōuli ke hoʻohui pū:
    • ʻeha iwi
    • ʻeha ma kou mau lima a me kou mau wāwae
    • haki iwi
    • ʻehaʻeha a nāwaliwali paha
  • Lilo iwi. Hiki i nā ʻōuli ke hoʻohui pū:
    • ʻeha iwi
    • ʻeha ma kou mau lima a me kou mau wāwae
    • haki iwi
  • Nā manaʻo hoʻohoka. Hiki i nā ʻōuli ke hoʻohui pū:
    • nalowale o ka ʻike
    • ʻūpē mākala
    • kuʻi niho
  • ʻO ka buildup o ka lactic acid a me ka hōʻino o ke ake. Hiki i nā ʻōuli ke hoʻohui pū:
    • luhi
    • ʻehaʻeha a me nāwaliwali
    • ʻeha a hōʻoluʻolu paha i kou ʻōpū (ʻōpū)
  • Immune reconstitution syndrome (ke hoʻomaikaʻi wikiwiki ka ʻōnaehana pale a hoʻomaka i "overwork"). Hiki i nā ʻōuli ke hoʻohui pū:
    • fiva
    • luhi
    • maʻi maʻi
    • pehu lymph node
    • ʻeha a ʻeha hoʻi o ka ʻili
    • pilikia hanu
    • pehu a puni kou mau maka
  • Hoʻololi i ka hoʻonohonoho momona a me ke ʻano o ke kino. Hiki i nā ʻōuli ke hoʻohui pū:
    • hoʻonui ka momona a puni kou waena (kino)
    • hoʻomohala o kahi momona momona ma ka hope o kou poʻohiwi
    • nā umauma hoʻonui ʻia (i nā kāne a me nā wahine ʻelua)
    • lilo o ke kaupaona i kou alo, lima, a me nā wāwae

Kaumaha hoʻonui

ʻAʻole ka hopena kaupaona i kahi hopena i kū i ka noiʻi olakino o Atripla. Eia nō naʻe, hiki i ka mālama ʻana i ka maʻi HIV ma ke ākea ke loaʻa i ke kaumaha. ʻO kēia no ka mea hiki i ka HIV ke hōʻemi i ke kaupaona, no laila ke mālama ʻana i ke ʻano ke kumu o ka hoʻi ʻana o kekahi o nā kaumaha i nalo.


E ʻike paha ka poʻe e lawe iā Atripla ua neʻe ko lākou kino momona i nā wahi like ʻole o ko lākou kino. Kapa ʻia kēia lipodystrophy. Hiki ke ʻākoakoa ka momona o ke kino i waenakonu o kou kino, e like me kou pūhaka, kou umauma, a me kou ʻāʻī. E neʻe paha ia mai kou mau lima a me kou mau wāwae.

ʻAʻole ʻike ʻia inā hele aku kēia mau hopena ma kahi o ka manawa, a inā e nalo paha ma hope o kou hōʻoki ʻana i ka hoʻohana ʻana iā Atripla. Inā ʻike ʻoe i kēia hopena, e haʻi i kāu kauka. E kuapo paha lākou iā ʻoe i kekahi lāʻau ʻokoʻa.

ʻO Pancreatitis

He kakaikahi ia, akā ua ʻike ʻia ka pancreatitis (inflamed pancreas) i ka poʻe e lawe ana i nā lāʻau i loaʻa ka efavirenz. ʻO Efavirenz kekahi o nā lāʻau ʻekolu i loko o Atripla.

Ua hoʻonui ʻia nā pae o nā pancreatic enzyme i kekahi poʻe e lawe ana i ka efavirenz, akā ʻaʻole ʻike ʻia inā pili kēia i ka pancreatitis.

E haʻi i kāu kauka inā loaʻa iā ʻoe nā hōʻailona kūpono o ka pancreatitis. Hoʻopili kēia i ka ʻeha i kou kino, nausea a i ʻole ka luaʻi, kahi puʻuwai wikiwiki, a me kahi ʻōpū palupalu a pehu paha. Hiki i kāu kauka ke hoʻololi iā ʻoe i kahi lāʻau ʻokoʻa.

Kaha: Hoʻomaopopo pinepine ʻia ʻo Pancreatitis me ka hoʻohana ʻana i nā lāʻau HIV e like me didanosine.

Nā hopena ʻē aʻe i nā keiki

I nā noiʻi maʻi o Atripla, ʻo ka hapa nui o nā hopena i nā keiki e like me nā poʻe mākua. ʻO Rash kekahi o nā hopena i kū pinepine i nā keiki.

Ua kū mai kahi ʻōpala ma 32% o nā keiki, ʻoiai he 26% wale nō o ka poʻe mākua i loaʻa ka ʻōhū. Ua ʻike pinepine ʻia ka hū i nā keiki ma kahi o 28 mau lā ma hope o ka hoʻomaka ʻana o ka mālama ʻana me Atripla. I mea e pale aku ai i kahi hua o kāu keiki, e ʻōlelo paha kā lākou kauka me ka hoʻohana ʻana i nā lāʻau āpau e like me nā antihistamines ma mua o ka hoʻomaka ʻana i ka lāʻau Atripla.

ʻO nā hopena ʻē aʻe i ʻike ʻia i nā keiki akā ʻaʻole hoʻokomo nā mākua i nā loli o ka ʻili o ka ʻili, e like me nā freckles a i ʻole ka ʻili i ʻeleʻele. Hana ʻia kēia ma nā poho o nā lima a me nā kapuaʻi o nā wāwae. Hoʻopili pū nā hopena i ka anemia, me nā ʻōuli e like me nā pae ikehu haʻahaʻa, ka puʻuwai wikiwiki, a me nā lima a me nā wāwae anuanu.

Rash

ʻO Rash kahi hopena ʻaoʻao maʻamau o ka mālama ʻana Atripla.

I nā hoʻokolohua hoʻokolohua, ua kū ka maʻi ma 26% o nā mākua i loaʻa ka efavirenz, kekahi o nā lāʻau i Atripla. Aia kekahi mau hōʻike e pili ana i nā rashes koʻikoʻi loa me ka hoʻohana ʻana o efavirenz, akā aia wale nō ma 0.1% o ka poʻe i aʻo ʻia. ʻO nā rashes i hana i nā palapū a i ʻole nā ​​ʻeha hāmama i kahi o 0.9% o ka poʻe.

ʻO ka hapa nui o nā rashes i ʻike ʻia me efavirenz he akahai a haʻahaʻa, me nā ʻulaʻula a me nā wahi patchy a me kekahi mau puʻupuʻu i ka ʻili. Kāhea ʻia kēia ʻano lapalapa he pehu maculopapular. Ua ʻike pinepine ʻia kēia mau huhū ma loko o 2 mau pule o ka hoʻomaka ʻana o ka mālama ʻana iā efavirenz a hele aku i loko o hoʻokahi mahina o ko lākou helehelena.

E haʻi i kāu kauka inā hoʻomohala ʻoe i kahi wīwī i ka lawe ʻana iā Atripla. Inā hoʻomohala ʻoe i ka pehu a i ʻole ke kuni, e hoʻōki i ka lawe ʻana iā Atripla a kāhea koke aku i kāu kauka. Hāʻawi paha kāu kauka iā ʻoe i nā lāʻau e mālama ai i ka hopena. Inā koʻikoʻi ka hū, hiki iā lākou ke hoʻololi iā ʻoe i kahi lāʻau ʻokoʻa.

Kaha: Ke ʻaelike mua kekahi kanaka i ka maʻi HIV, hiki i ka ʻōlapa ke hōʻailona mua. Kū mau kēia maʻa mau no 2 a 4 mau pule. Akā inā ua loaʻa ʻoe iā HIV no kekahi manawa a hoʻomaka wale ka mālama ʻana me Atripla, no Atripla paha ka hū hou.

Kaumaha

ʻO ke kaumaha ka hopena maʻamau i nā hoʻokolohua hoʻokolohua o Atripla. Ua hana ʻia ma 9% o ka poʻe e lawe nei i ka lāʻau.

E haʻi koke i kāu kauka inā loaʻa nā ʻōuli o ke kaumaha. Hiki i kēia ke hoʻopili i nā manaʻo o ke kaumaha, ka manaʻolana ʻole, a me ka nalo ʻole o ka hoihoi i nā hana o kēlā me kēia lā. Hiki i kāu kauka ke hoʻololi iā ʻoe i kahi lāʻau ʻokoʻa HIV. Paipai paha lākou i ka hoʻomaʻamaʻa no kāu ʻōuli kaumaha.

Kāohi ʻana i ke ola

  • Inā ʻike ʻoe i kahi mea e makaʻu koke ana i ka hōʻeha ponoʻī, pepehi kanaka ʻana, a i ʻole hōʻeha ʻana i kekahi kanaka.
  • Kāhea iā 911 a i ʻole ka helu kūloko kūloko.
  • Noho me ke kanaka a hiki i ka hōʻea ʻana mai o ke kōkua ʻoihana.
  • Wehe i nā mea kaua, nā lāʻau, a i ʻole nā ​​mea ʻino ʻino ʻē aʻe.
  • E hoʻolohe i ke kanaka me ka hoʻokolokolo ʻole.
  • Inā ʻoe a i ʻole kekahi mea āu e ʻike nei e noʻonoʻo nei i ka pepehi kanaka, hiki i kahi laina pale pale ke kōkua. Loaʻa ka National Suicide Prevention Lifeline 24 mau hola i kēlā me kēia lā ma 800-273-8255.

ʻO ke kumukūʻai Atripla

E like me nā lāʻau āpau, hiki ke hoʻololi ke kumukūʻai o Atripla.

E hilinaʻi kāu kumukūʻai maoli i kāu ʻinikua.

Kōkua kālā a me nā ʻinikua

Inā makemake ʻoe i kākoʻo kālā e uku no Atripla, a i ʻole inā pono ʻoe e kōkua e hoʻomaopopo i kāu ʻinikua uhi, loaʻa ke kōkua.

Hāʻawi ʻo Gilead Science, Inc., ka mea hana a Atripla, i kahi papahana i kapa ʻia Advancing Access. No ka ʻike hou aku a e ʻike inā he kūpono ʻoe no ke kākoʻo, kāhea iā 800-226-2056 a i ʻole kipa i ka pūnaewele pūnaewele.

Hoʻohana ʻo Atripla

Ua ʻae ka Food and Drug Administration (FDA) i nā lāʻau i kuhikuhi ʻia e like me Atripla e mālama i kekahi mau ʻano. Ua ʻae ʻia ʻo Atripla e mālama i ka maʻi HIV.

Atripla no ka maʻi HIV

Ua ʻae ʻia ʻo Atripla e mālama i ka maʻi HIV i nā mākua a me nā keiki e kaupaona ma ka liʻiliʻi 88 paona (40 kilokilo). Hoʻohana ʻia ʻo Atripla e ia iho a i ʻole hui pū ʻia me nā lāʻau ʻē aʻe o ka HIV.

Ua ʻae ʻia ka hapa nui o nā lāʻau hou no ka poʻe ʻaʻole i lawe i nā lāʻau HIV a paʻa paha i kahi lāʻau HIV hou. ʻAʻole loaʻa iā Atripla kēlā hoʻohana kikoʻī i ʻae ʻia.

Hoʻohana i ʻae ʻole ʻia

ʻAʻole ʻae ʻia ʻo Atripla no nā hoʻohana ʻē aʻe. Hoʻohana wale ʻia ia e mālama ai i ka maʻi HIV.

Atripla no ka maʻi hepa B

ʻAʻole ʻae ʻia ʻo Atripla no ka maʻi hepa B a pono ʻole e hoʻohana e mālama iā ia. Eia nō naʻe, hoʻohana ʻia kekahi o nā lāʻau i Atripla (tenofovir disoproxil fumarate) e mālama ai i ka maʻi hepitis B.

Atripla no PEP

ʻAʻole ʻae ʻia ʻo Atripla a ʻaʻole pono e hoʻohana ʻia no ka prophylaxis post-exp (PEP). Pili ʻo PEP i ka hoʻohana ʻana i nā lāʻau HIV ma hope o ka hiki ʻana i ka maʻi HIV ke pale aku i ka maʻi.

Eia hou, ʻaʻole ʻae ʻia ʻo Atripla a ʻaʻole pono e hoʻohana ʻia no ka prophylaxis pre-exposed (PrEP). Pili ʻo PrEP i ka hoʻohana ʻana o nā lāʻau HIV ma mua o ka hiki ʻana i ka maʻi HIV ke pale aku i ka maʻi.

ʻO ka lāʻau wale nō i ʻae ʻia e ka FDA no PrEP ʻo Truvada, kahi e loaʻa ai ka emtricitabine a me ka tenofovir disoproxil fumarate. ʻOiai ʻo Atripla i loko o kēia mau lāʻau ʻelua, ʻaʻole ia i aʻo ʻia ma ke ʻano he kaohi pale no ka maʻi HIV.

Atripla no nā keiki

Hiki ke hoʻohana ʻia ʻo Atripla e mālama i ka maʻi HIV i nā poʻe o nā makahiki āpau ke kau lākou ma ka liʻiliʻi 88 paona (40 mau kilokika). Pākuʻi ʻia kēia me nā keiki.

ʻ dosagekuhi Atripla

Hōʻike ka ʻikepili aʻe i nā lāʻau i hoʻohana pinepine ʻia a koi ʻia paha. Eia nō naʻe, e mālama pono i nā lāʻau a ke kauka i kuhikuhi ai nāu.

Nā ʻano lāʻau a me nā ikaika

Hele mai ʻo Atripla ma ke ʻano he papaha waha. ʻEkolu mau lāʻau i loko o kēlā me kēia pāka.

  • 600 mg o efavirenz
  • 300 mg o tenofovir disoproxil fumarate
  • 200 mg o emtricitabine

Nā hana no ka maʻi HIV

Hoʻokahi Atripla papa e lawe i hoʻokahi manawa i kēlā me kēia lā ma kahi ʻōpū nele (me ka ʻole o ka meaʻai). I ka hapanui o nā hihia, pono e lawe i ka wā moe.

ʻĀpana pēpē

ʻO ke ana Atripla no nā keiki e like me ke ana no nā mākua. ʻAʻole e loli ke ana ma muli o ka makahiki.

He aha inā e haʻo wau i kahi lāʻau?

Inā lawe ʻoe iā Atripla a haʻalele i kahi lāʻau, lawe i ka lāʻau aʻe ke hoʻomanaʻo koke ʻoe. Inā kokoke i ka manawa no kāu kau ma hope, e lawe wale i kēlā kau ma hope. ʻAʻole pono ʻoe e pāpālua i kāu lāʻau no ka make ʻana o ka lāʻau.

Pono wau e hoʻohana i kēia lāʻau lōʻihi?

Inā hoʻoholo ʻoe a me kāu kauka he lapaʻau maikaʻi ʻo Atripla nāu, pono paha ʻoe e lawe i kahi wā lōʻihi.

I ka manawa i hoʻomaka ai ʻoe i ka lāʻau lapaʻau, mai hōʻoki i ka lawe ʻana iā Atripla me ka walaʻau ʻole ʻana me kāu kauka.

Hoʻopili i kāu hoʻolālā hoʻomaʻamaʻa Atripla

Lawe i nā papa Atripla e like me ka ʻōlelo a kāu kauka iā ʻoe he mea nui loa. ʻO ka lawe mau ʻana iā Atripla e hoʻonui i kou manawa e kūleʻa ai ka lāʻau.

Hiki i nā nalo ke nalo ke hoʻopili i ka maikaʻi o ka hana a Atripla e mālama i ka maʻi HIV. Inā ʻoe e nalo i nā lāʻau, hiki iā ʻoe ke hoʻomake i ke kūʻē iā Atripla. ʻO ke kumu o kēia ʻaʻole hiki i ka lāʻau ke hana hou e mālama i kāu maʻi HIV.

Inā loaʻa iā ʻoe ka maʻi hepitis B a me ka HIV, loaʻa iā ʻoe kahi pilikia hou aʻe. ʻO nā nalo o Atripla e lilo i mea e ʻoi aku ai kou maʻi hepatitis B.

E mālama pono i nā kuhikuhi a kāu kauka a lawe iā Atripla i hoʻokahi manawa i ka lā, i kēlā me kēia lā, ke ʻole ke kauka e haʻi aku iā ʻoe i kahi ʻē aʻe. Hiki ke kōkua i ka hoʻohana ʻana i kahi mea hana hoʻomanaʻo i ka lawe ʻana iā Atripla i kēlā me kēia lā.

Inā he mau nīnau a hopohopo paha kāu e pili ana i kāu lāʻau Atripla, e kamaʻilio me kāu kauka. Hiki iā lākou ke kōkua i ka hoʻoponopono ʻana i nā pilikia i loaʻa iā ʻoe a kōkua e hōʻoia iā Atripla e hana maikaʻi nei nāu.

Nā koho ʻē aʻe iā Atripla

Ma waho o ka Atripla, nui a hewahewa nā lāʻau i loaʻa e hiki ke mālama i ka maʻi HIV. Kūpono paha kekahi iā ʻoe ma mua o nā poʻe ʻē aʻe. Inā makemake ʻoe i ka ʻimi ʻana i kahi ʻē aʻe i Atripla, e kamaʻilio me kāu kauka e aʻo hou e pili ana i nā lāʻau ʻē aʻe e holo pono paha iā ʻoe.

ʻO nā lāʻau hoʻohui ʻē aʻe

Pono nā kānaka āpau i loaʻa i ka maʻi HIV e lawe i nā lāʻau hou aku ma mua o hoʻokahi. No kēia kumu, nui nā lāʻau lapaʻau HIV i loaʻa. Loaʻa i loko o kēia mau lāʻau i hoʻokahi lāʻau. ʻO Atripla kahi lāʻau hoʻohui e loaʻa nā lāʻau ʻekolu: emtricitabine, tenofovir disoproxil fumarate, a me efavirenz.

Loaʻa nā laʻana o nā lāʻau hoʻohui ʻē aʻe no ka mālama ʻana i ka maʻi HIV.

  • ʻO Biktarvy (bictegravir, emtricitabine, a me tenofovir alafenamide)
  • ʻO Complera (emtricitabine, rilpivirine, a me tenofovir disoproxil fumarate)
  • Descovy (emtricitabine a me tenofovir alafenamide)
  • ʻO Genvoya (elvitegravir, cobicistat, emtricitabine, a me tenofovir alafenamide)
  • ʻO Juluca (dolutegravir a me rilpivirine)
  • ʻO Odefsey (emtricitabine, rilpivirine, a me tenofovir alafenamide)
  • Stribild (elvitegravir, cobicistat, emtricitabine, a me tenofovir disoproxil fumarate)
  • Symtuza (darunavir, cobicistat, emtricitabine, a me tenofovir alafenamide)
  • Triumeq (abacavir, dolutegravir, a me lamivudine)
  • Truvada (emtricitabine a me tenofovir disoproxil fumarate)

Nā lāʻau lapaʻau pākahi

No kēlā me kēia kanaka me ka HIV, e hoʻolālā kā lākou kauka i kahi hoʻolālā lapaʻau no lākou. He lāʻau hoʻohui paha kēia, a i ʻole he hoʻokaʻawale ʻokoʻa paha nā lāʻau.

Loaʻa ka nui o nā lāʻau i loaʻa pū i nā lāʻau HIV. Hiki i kāu kauka ke haʻi hou aku iā ʻoe e pili ana i nā lāʻau i kūpono iā ʻoe.

Atripla vs. Genvoya

Mahalo paha ʻoe pehea e hoʻohālikelike ai ʻo Atripla me nā lāʻau ʻē aʻe i kuhikuhi ʻia no nā hoʻohana like. Ma aneʻi, nānā mākou i ka like a like ʻole o Atripla a me Genvoya.

Hoʻohana

Ua ʻae ʻia ʻo Atripla lāua ʻo Genvoya e mālama i ka maʻi HIV. Ua ʻae ʻia ʻo Genvoya no ka hoʻohana ʻana i nā poʻe o nā makahiki āpau ke lōʻihi lākou ma ka liʻiliʻi 55 paona (25 kilokilo). Atripla, ma ka ʻaoʻao ʻē aʻe, ʻae ʻia no ka hoʻohana ʻana i nā poʻe o nā makahiki āpau ke kau lākou ma ka liʻiliʻi 88 paona (40 kilokilo).

Nā ʻano lāʻau a me ka hoʻoponopono ʻana

Hele mai ʻo Atripla lāua ʻo Genvoya ma ke ʻano he mau papa waha i lawe ʻia i hoʻokahi manawa i kēlā me kēia lā. Lawe ʻia ʻo Genvoya me ka meaʻai, ʻoiai ʻo Atripla e lawe ʻia i kahi ʻōpū nele. A ʻoiai ʻo Genvoya hiki ke lawe ʻia i kēlā me kēia manawa i ke ao, ua koi ʻia e lawe iā Atripla i ka wā moe e kōkua ai i ka pale ʻana i kekahi mau hopena ʻaoʻao.

Loaʻa i kēlā me kēia papa Atripla nā lāʻau emtricitabine, efavirenz, a me tenofovir disoproxil fumarate. Loaʻa i kēlā me kēia papa Genvoya nā lāʻau emtricitabine, elvitegravir, cobicistat, a me tenofovir alafenamide.

Nā hopena a me nā pilikia

Loaʻa nā hopena like ʻo Atripla a me Genvoya i ke kino a no laila e like me nā hopena ʻaoʻao like loa. Ma lalo nā hiʻohiʻona o kēia mau hopena ʻaoʻao.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻē aʻe i hiki ke hana ʻia me Atripla, me Genvoya, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

  • Hiki ke hana me Atripla:
    • kaumaha
    • nā maʻi maʻi hanu o luna
    • hopohopo
    • eha ka 'ā'ī
    • ka luaʻi
    • ʻūpā
    • hūwī
    • pilikia hiamoe
  • Hiki ke hana me Genvoya:
    • hoʻonui i nā kiʻekiʻe o ka LDL cholesterol
  • Hiki ke hana me nā Atripla a me Genvoya:
    • pāhoehoe
    • nausea
    • ʻeha poʻo
    • luhi
    • hoʻonui i ka nui o nā pae kolesterol

Nā hopena hopena koʻikoʻi

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana ʻia me Atripla, me Genvoya, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

  • Hiki ke hana me Atripla:
    • loli ke olakino noʻonoʻo, e like me ke kaumaha loa a i ʻole ka hana kolohe
    • haʻalulu
    • nā hoʻololi i ka wahi momona ma ke kino holoʻokoʻa
  • Hiki ke hana me Genvoya:
    • kekahi mau hopena koʻikoʻi koʻikoʻi
  • Hiki ke hana me nā Atripla a me Genvoya:
    • nalowale iwi
    • ʻoi loa ka maikaʻi o ka maʻi hepatitis B * (inā loaʻa iā ʻoe ka maʻi maʻi)
    • immune reconstitution syndrome (ke hoʻomaikaʻi wikiwiki ka ʻōnaehana pale a hoʻomaka i "overwork")
    • hōʻino kīhāpai * *
    • lactic acidosis (kahi hana ʻino weliweli o ke kino)
    • maʻi maʻi akepaʻa (hoʻonui ʻia ke ake me ka steatosis)

* ʻO ʻAtripla lāua ʻo Genvoya i kahi ʻōlelo aʻoaʻo mai ka FDA e pili ana i ka hōʻino ʻana o ka maʻi hepitis B. ʻO ka ʻōlelo aʻoaʻo i pahu ʻia ka ʻōlelo aʻo ikaika loa a ka FDA e koi ai. Hoʻomaopopo ia i nā kauka a me nā mea maʻi e pili ana i nā hopena lāʻau e weliweli paha.

* * ʻO Tenofovir, kekahi o nā lāʻau i loko o Genvoya a me Atripla, ua hoʻopili ʻia i ka hōʻino ʻana o ka hakuʻala. Eia nō naʻe, ʻo ke ʻano o ka tenofovir ma Genvoya (tenofovir alafenamide) ʻoi aku ka liʻiliʻi o ka hōʻino ʻana i nā puʻupaʻa ma mua o ke ʻano ma Atripla (tenofovir disoproxil fumarate).

Ka hoʻokō ʻana

ʻAʻole i hoʻohālikelike pololei ʻia kēia mau lāʻau i loko o nā noiʻi haukapila, akā ua ʻike nā noiʻi ua maikaʻi nā Atripla a me Genvoya no ka mālama ʻana i ka maʻi HIV.

Eia nō naʻe, ʻaʻole koi ʻia kekahi lāʻau e like me ke koho mua loa no ka mālama ʻana no ka hapanui o nā kānaka me ka maʻi HIV. ʻO kēia no ka mea ʻo Atripla lāua ʻo Genvoya he mau lāʻau kahiko ʻo HIV, a he loaʻa nā lāʻau hou i loaʻa nā koho ʻoi aku ka maikaʻi. ʻOi aku ka maikaʻi o nā lāʻau ʻoi aku ka maʻi ʻoi aku ka liʻiliʻi o nā hopena ma mua o nā lāʻau kahiko.

Kūpono paha ʻo Atripla a me Genvoya no kekahi poʻe, akā ma ka laulā, ʻaʻole lākou ke koho mua a ke kauka e koi ai no ka hapa nui o ka poʻe.

Nā kumukūʻai

ʻO Atripla lāua ʻo Genvoya nā lāʻau lapaʻau inoa inoa ʻelua. ʻAʻole loaʻa lākou i nā ʻano laulā, ʻoi aku ka liʻiliʻi ma mua o nā lāʻau lapaʻau inoa.

Wahi a nā kuhi ma GoodRx.com, uku liʻiliʻi paha ʻo Atripla ma mua o Genvoya. ʻO ke kumukūʻai maoli āu e uku ai no kēlā me kēia lāʻau e pili ana i kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

Atripla vs. nā lāʻau ʻē aʻe

Ma waho o Genvoya (ma luna), kuhikuhi ʻia nā lāʻau ʻē aʻe e mālama i ka maʻi HIV. Ma lalo nā hoʻohālikelike ma waena o Atripla a me kekahi mau lāʻau HIV.

Atripla vs. Truvada

ʻO Atripla kahi lāʻau hoʻohui e loaʻa nā lāʻau emtricitabine, tenofovir disoproxil fumarate, a me efavirenz. ʻO Truvada kahi lāʻau hoʻohui pū, a loaʻa nā lāʻau like ʻelua i loko o Atripla: emtricitabine a me tenofovir disoproxil fumarate.

Hoʻohana

Ua ʻae ʻia ʻo Atripla lāua ʻo Truvada no ka mālama ʻana i ka maʻi HIV. ʻAe ʻia ʻo Atripla e hoʻohana nona iho, akā ʻae wale ʻia ʻo Truvada no ka hoʻohana ʻana me dolutegravir (Tivicay) a i ʻole nā ​​lāʻau HIV ʻē aʻe.

ʻAe ʻia ʻo Atripla no ka hoʻohana ʻana i nā poʻe o nā makahiki āpau ke kau lākou ma ka liʻiliʻi 88 paona (40 mau kilokika). Ua ʻae ʻia ʻo Truvada e mālama iā HIV i nā poʻe o nā makahiki āpau ke kau lākou ma ka liʻiliʻi 37 paona (17 kilokilo).

Ua ʻae ʻia ʻo Truvada no ka pale ʻana i ka maʻi HIV. ʻAe wale ʻia ʻo Atripla e mālama i ka maʻi HIV.

Nā ʻano lāʻau a me ka hoʻoponopono ʻana

Hele mai ʻo Atripla lāua ʻo Truvada ma ke ʻano he papa ʻōlelo waha i lawe ʻia i hoʻokahi manawa i kēlā me kēia lā. Hiki ke kiʻi ʻia ʻo Truvada me ka ʻole o ka meaʻai, ʻoiai ʻo Atripla e lawe ʻia i kahi ʻōpū nele. A ʻoiai ʻo Truvada hiki ke lawe ʻia i kēlā me kēia manawa i ke ao, koi ʻia ʻoe e lawe iā Atripla i ka wā moe e kōkua i ka pale ʻana i nā hopena ʻaoʻao.

Nā hopena a me nā pilikia

Loaʻa nā Atripla i nā lāʻau like me Truvada, a me efavirenz. No laila, he hopena like ko lākou.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻē aʻe i hiki ke hana ʻia me Atripla a me Truvada (ke lawe pākahi ʻia). Kaha: Nā hopena ʻaoʻao no Truvada i helu ʻia ma aneʻi mai kahi hoʻokolohua hoʻokolohua kahi i lawe ʻia ai ʻo Truvada me efavirenz.

  • Hiki ke hana me nā Atripla a me Truvada:
    • pāhoehoe
    • nausea a me ka luaʻi
    • ʻūpā
    • ʻeha poʻo
    • luhi
    • pilikia hiamoe
    • eha ka 'ā'ī
    • nā maʻi hanu
    • moeʻuhane ʻino
    • hūwī
    • hoʻonui i ka nui o nā pae kolesterol

Nā hopena hopena koʻikoʻi

Loaʻa i kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana me Atripla a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia). Kaha: Nā hopena ʻaoʻao no Truvada i helu ʻia ma aneʻi mai kahi hoʻokolohua hoʻokolohua kahi i lawe ʻia ai ʻo Truvada me efavirenz.

  • Hiki ke hana me Atripla:
    • haʻalulu
    • nā hoʻololi i ka wahi momona ma ke kino holoʻokoʻa
  • Hiki ke hana me nā Atripla a me Truvada:
    • loli ke olakino noʻonoʻo, e like me ke kaumaha loa a i ʻole ka hana kolohe
    • ʻoi aku ka maikaʻi o ka maʻi hepatitis B * (inā loaʻa iā ʻoe ka maʻi maʻi)
    • pale reconstitution maʻi pale (ke hoʻomaikaʻi wikiwiki ka ʻōnaehana pale a hoʻomaka i "overwork")
    • nalowale iwi
    • hōʻino kīhāpai * *
    • lactic acidosis (kahi hana ʻino weliweli o ke kino)
    • maʻi maʻi akepaʻa (hoʻonui ʻia ke ake me ka steatosis)

* ʻO Atripla lāua ʻo Truvada he mau ʻōlelo aʻoaʻo a ka pahu mai ka FDA e pili ana i ka hōʻino ʻana o ka maʻi hepitis B. He ʻōlelo aʻoaʻo ka pahu ka ʻōlelo aʻo ikaika a ka FDA e koi ai. Hoʻomaopopo ia i nā kauka a me nā mea maʻi e pili ana i nā hopena lāʻau e weliweli paha.

* * Tenofovir, kekahi o nā lāʻau i loko o Truvada a me Atripla, ua hoʻopili ʻia i ka hōʻino ʻana o ka hakuʻala.

Ka hoʻokō ʻana

ʻAʻole i hoʻohālikelike pololei ʻia kēia mau lāʻau i loko o nā noiʻi haukapila, akā ua ʻike nā noiʻi ua maikaʻi nā Atripla a me Truvada no ka mālama ʻana i ka maʻi HIV.

ʻOiai hiki ke maikaʻi ʻo Atripla i ka mālama ʻana i ka maʻi HIV, ʻaʻole ia e koi ʻia ma ke ʻano he koho mua loa no ka maʻi HIV. ʻO kēia no ka mea hiki i nā lāʻau hou ke mālama i ka maʻi HIV akā ʻoi aku paha ka hopena o ka hopena ma mua o Atripla.

Hoʻohana ʻia ʻo Truvada me ka dolutegravir (Tivicay), akā naʻe, ua ʻōlelo ʻia ma ke ʻano he koho mua loa no ka hapa nui o ka poʻe me ka maʻi HIV.

Nā kumukūʻai

ʻO Atripla lāua ʻo Truvada nā lāʻau lapaʻau inoa inoa ʻelua. ʻAʻole lākou i loaʻa i nā ʻano laulā, ʻoi aku ka liʻiliʻi o ke kumu kūʻai ma mua o nā lāʻau lapaʻau inoa.

Wahi a nā kuhi ma GoodRx.com, ʻoi aku ke kumukūʻai ʻo Atripla ma mua o Truvada. ʻO ke kumukūʻai maoli āu e uku ai no kēlā me kēia lāʻau e pili ana i kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

Atripla vs. Complera

ʻO Atripla kahi lāʻau hoʻohui e loaʻa nā lāʻau emtricitabine, tenofovir disoproxil fumarate, a me efavirenz. ʻO ka Complera kahi lāʻau hoʻohui pū, a loaʻa nā lāʻau like ʻelua i Atripla: emtricitabine a me tenofovir disoproxil fumarate. ʻO ke kolu o nā lāʻau lapaʻau ʻo rilpivirine.

Hoʻohana

Ua ʻae ʻia ʻo Atripla lāua ʻo Complera no ka mālama ʻana i ka maʻi HIV.

ʻAe ʻia ʻo Atripla no ka hoʻohana ʻana i nā poʻe o nā makahiki āpau ke kau lākou ma ka liʻiliʻi 88 paona (40 mau kilokika). ʻO Complera, ma ka ʻaoʻao ʻē aʻe, ʻae ʻia no ka hoʻohana ʻana i nā poʻe o nā makahiki āpau ke kau lākou ma ka liʻiliʻi 77 paona (35 kilo).

Hoʻohana wale ʻia ʻo Complera i ka poʻe i loaʻa kahi viral viral haʻahaʻa ma mua o ka hoʻomaka ʻana i ka lāʻau. ʻAʻohe o ʻAtripla kēia palena.

Nā ʻano lāʻau a me ka hoʻoponopono ʻana

Hele mai ʻo Atripla lāua ʻo Complera ma ke ʻano he papa ʻōlelo waha i lawe ʻia i hoʻokahi manawa i kēlā me kēia lā. Lawe ʻia ʻo Complera me ka meaʻai, ʻoiai ʻo Atripla e lawe ʻia i kahi ʻōpū nele. A ʻoiai ʻo Complera hiki ke lawe ʻia i kēlā me kēia manawa i ke ao, koi ʻia ʻoe e lawe iā Atripla i ka wā moe e kōkua i ka pale ʻana i nā hopena ʻaoʻao.

Nā hopena a me nā pilikia

Loaʻa nā lāʻau like ʻo Atripla a me Complera. No laila, he hopena like ko lākou.

Nā hopena ʻaoʻao hou aʻe

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻē aʻe i hiki ke hana ʻia me Atripla, me Complera, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

  • Hiki ke hana me Atripla:
    • kekahi mau hopena ʻaoʻao maʻamau
  • Hiki ke hana me Complera:
    • kekahi mau hopena ʻaoʻao maʻamau
  • Hiki ke hana me nā Atripla a me Complera:
    • pāhoehoe
    • nausea a me ka luaʻi
    • ʻūpā
    • ʻeha poʻo
    • luhi
    • pilikia hiamoe
    • eha ka 'ā'ī
    • nā maʻi maʻi hanu o luna
    • moeʻuhane ʻino
    • hūwī
    • kaumaha
    • hopohopo
    • hoʻonui i ka nui o nā pae kolesterol

Nā hopena hopena koʻikoʻi

Aia i loko o kēia mau papa inoa nā laʻana o nā hopena ʻino e hiki ke hana ʻia me Atripla, me Complera, a i ʻole me nā lāʻau ʻelua (ke lawe pākahi ʻia).

  • Hiki ke hana me Atripla:
    • haʻalulu
    • nā hoʻololi i ka wahi momona ma ke kino holoʻokoʻa
  • Hiki ke hana me Complera:
    • pehu i loko o kāu gallbladder
    • pōhaku ʻalā
  • Hiki ke hana me nā Atripla a me Complera:
    • loli ke olakino noʻonoʻo, e like me ke kaumaha loa a i ʻole ka hana kolohe
    • ʻoi loa ka maikaʻi o ka maʻi hepatitis B * (inā loaʻa iā ʻoe ka maʻi maʻi)
    • immune reconstitution syndrome (ke hoʻomaikaʻi wikiwiki ka ʻōnaehana pale a hoʻomaka i "overwork")
    • nalowale iwi
    • hōʻino kīhāpai * *
    • lactic acidosis (kahi hana ʻino weliweli o ke kino)
    • maʻi ate loa (hoʻonui ʻia ke ake me ka steatosis)

* ʻO ʻAtripla lāua ʻo Complera i kahi ʻatikala pahu mai ka FDA e pili ana i ka hōʻino ʻana o ka maʻi hepitis B. ʻO ka ʻōlelo aʻoaʻo pahu ka ʻōlelo aʻo ikaika loa a ka FDA e koi ai. Hoʻomaopopo ia i nā kauka a me nā mea maʻi e pili ana i nā hopena lāʻau e weliweli paha.

* * Tenofovir, kekahi o nā lāʻau i loko o ka Complera a me ka Atripla, ua hoʻopili ʻia i ka hōʻino ʻana o ka hakuʻala.

Ka hoʻokō ʻana

Hoʻohālikelike ʻia ka hoʻohana ʻana o nā lāʻau i Atripla (efavirenz, emtricitabine, a me tenofovir disoproxil fumarate) me ka hoʻohana ʻana o Complera i kahi noiʻi hoʻokolohua. Ua ʻike ʻia nā kuʻina ʻelua i like ka maikaʻi no ka mālama ʻana i ka maʻi HIV.

I ka poʻe i mālama ʻole ʻia no ka maʻi HIV ma mua, ua kūleʻa ka lawelawe ʻana ʻo Complera a me ka huina Atripla he 77% i ka pule 96. Ua manaʻo ʻia he kūleʻa ka hoʻomaʻamaʻa inā ʻoi aku ka nui o ka viral viral o ke kanaka ma mua o 50 i ka hopena o ke aʻo ʻana.

Eia nō naʻe, ʻaʻole loaʻa ka pōmaikaʻi iā 8% o ka poʻe i lawe i ka huikau Atripla, ʻoiai ʻaʻole loaʻa ka pōmaikaʻi iā 14% o ka poʻe i lawe iā Complera. Hōʻike kēia i ka loaʻa ʻana o ka hoʻoponopono maikaʻi ʻo Complera ma mua o ka hui ʻana o ka lāʻau Atripla.

ʻAʻole ʻo Atripla a me Complera paha e koi ʻia ma ke ʻano he koho mua loa no ka hapanui o nā poʻe me ka maʻi HIV. Kūpono paha kēia mau lāʻau no kekahi poʻe, akā ma ka laulaha, paipai pinepine ʻia nā lāʻau hou. ʻO kēia no ka mea ʻoi aku ka maikaʻi o nā lāʻau hou, e like me Biktarvy a i ʻole Triumeq, a ʻoi aku ka liʻiliʻi o nā hopena.

Nā kumukūʻai

ʻO Atripla lāua ʻo Complera nā lāʻau lapaʻau inoa ʻelua. ʻAʻohe o nā ʻano generic i kēia manawa no kekahi lāʻau. ʻOi aku ke kumu kūʻai o nā lāʻau lapaʻau inoa inoa ma mua o nā generics.

Wahi a nā wānana mai GoodRx.com, Atripla a me Complera ma ke ʻano he kumukūʻai like. ʻO ke kumukūʻai maoli āu e uku ai no kēlā me kēia lāʻau e pili ana i kāu hoʻolālā ʻinikua, kou wahi, a me ka lāʻau kūʻai āu e hoʻohana ai.

Pehea e lawe ai iā Atripla

Pono ʻoe e lawe iā Atripla e like me kāu kauka a i ʻole nā ​​ʻōkuhi mālama ola.

Manawa

Lawe ʻoe iā Atripla i ka manawa like i kēlā me kēia lā, ʻoi aku ka maikaʻi i ka wā hiamoe. Lawe iā ia i ka wā moe e kōkua paha i ka hōʻoluʻolu i kekahi o nā hopena ʻaoʻao, e like me ka pilikia i ka noʻonoʻo ʻana a me ka puʻupuʻu.

Lawe iā Atripla ma kahi ʻōpū nele

Lawe ʻoe iā Atripla ma kahi ʻōpū nele (me ka ʻole o ka meaʻai). ʻO ka lawe ʻana iā Atripla me ka meaʻai e hoʻonui i nā hopena o ka lāʻau. ʻO ka loaʻa ʻana o nā lāʻau i loko o kāu ʻōnaehana hiki ke alakaʻi i nā hopena ʻino.

Hiki iā Atripla ke haki?

Ma ka laulā, ʻaʻole pono ia e wāwahi, ʻānai, a nau i nā papa Atripla. E ale wale ʻia lākou.

Inā pilikia ʻoe i ka ale ʻana i nā papa āpau, e kamaʻilio me kāu kauka e pili ana i nā lāʻau ʻē aʻe e ʻoi aku ka maikaʻi iā ʻoe.

ʻAtripla a me ka waiʻona

ʻOi aku ka maikaʻi o ka hōʻalo ʻana i ka inu wai ʻona ʻoiai e lawe ana iā Atripla. ʻO kēia no ka hoʻohui ʻana i ka ʻalekohola a me Atripla ke alakaʻi i nā hopena ʻē aʻe o ka lāʻau. Hiki i kēia mau mea ke:

  • ʻūpā
  • pilikia pilikia hiamoe
  • huikau
  • nā ʻōlelo hoʻohiwahiwa
  • pilikia pilikia

Inā pilikia ʻoe i ka hōʻalo ʻana i ka wai ʻona, e hoʻomaopopo i kāu kauka ma mua o kou hoʻomaka ʻana i ka lāʻau me Atripla. Hōʻike paha lākou i kahi lāʻau ʻokoʻa.

Nā pilina Atripla

Hiki i ka Atripla ke launa pū me nā lāʻau like ʻole a me kekahi mau mea hoʻopili a me nā meaʻai.

Hiki i nā launa like ʻole ke kumu i nā hopena like ʻole. ʻO kahi laʻana, hiki i kekahi ke hoʻopilikia i ka maikaʻi o ka hana ʻana o ka lāʻau, ʻoiai ʻo kekahi e hoʻonui i nā hopena ʻē aʻe.

Atripla a me nā lāʻau ʻē aʻe

Ma lalo ka papa inoa o nā lāʻau i hiki ke launa pū me Atripla. ʻAʻole loaʻa i kēia papa inoa nā lāʻau āpau e launa pū me Atripla. Nui nā lāʻau ʻē aʻe i hiki ke launa pū me Atripla.

Ma mua o ka lawe ʻana iā Atripla, e hoʻomaopopo pono e haʻi aku i kāu kauka a me ka kauka lāʻau e pili ana i nā kauka a pau, ka mea kūʻai aku a me nā lāʻau ʻē aʻe āu e lawe ai. Eia kekahi, e haʻi iā lākou e pili ana i nā wikamina, nā mea kanu, a me nā mea hoʻopiha āu e hoʻohana ai. Hiki ke kōkua i ka hāʻawi ʻana i kēia ʻike iā ʻoe e hōʻalo i nā launa ʻole.

Inā he mau nīnau kāu e pili ana i nā launa lāʻau e hoʻopili iā ʻoe, e nīnau i kāu kauka a kauka paha.

Nā lāʻau HIV kekahi

Hana pū ʻo Atripla me nā lāʻau ʻē aʻe he nui o ka HIV. Mai hoʻomaka i ka lawe ʻana i nā lāʻau he nui no ka HIV ke ʻole i kauoha ʻia e kāu kauka. ʻO ka lawe ʻana iā Atripla me kekahi mau lāʻau HIV e hōʻemi paha i nā hopena o kēia mau lāʻau a hoʻonui paha i kou hopena i nā hopena ʻaoʻao.

Eia kekahi laʻana o kēia mau lāʻau HIV:

  • nā mea hoʻopale protease, e like me:
    • atazanavir
    • fosamprenavir calcium
    • indinavir
    • darunavir / ritonavir
    • lopinavir / ritonavir
    • ritonavir
    • saquinavir
  • non-nucleoside hoʻohuli transcriptase nā mea hoʻopale (NNRTI), e like me:
    • rilpivirine
    • etravirine
    • doravirine
  • maraviroc, ʻo ia ka mea kūʻē CCR5
  • didanosine, ʻo ia kahi mea hoʻohiwahiwa transposase nucleoside huli (NRTI)
  • raltegravir, ʻo ia ka mea hoʻowahāwahā integrase

Nā lāʻau hepatitis C kekahi

Lawe iā Atripla me kekahi mau lāʻau hepatitis C hiki ke hōʻemi i ka lāʻau. Hiki iā ia ke pale aku i kou kino i nā lāʻau hepatitis C. Me ke kūʻē ʻana, ʻaʻole holo pono paha nā lāʻau iā ʻoe. No nā lāʻau hepatitis C ʻē aʻe, lawe iā Atripla me lākou hiki ke hoʻonui i nā hopena ʻaoʻao o Atripla.

ʻO nā laʻana o nā lāʻau hepatitis C ʻaʻole pono e lawe ʻia me Atripla:

  • Epclusa (sofosbuvir / velpatasvir)
  • Harvoni (ledipasvir / sofosbuvir)
  • Mavyret (glecaprevir / pibrentasvir)
  • ʻO Olopa (simeprevir)
  • ʻO Victrelis (boceprevir)
  • ʻO Vosevi (sofosbuvir / velpatasvir / voxilaprevir)
  • Zepatier (elbasvir / grazoprevir)

Nā lāʻau lapaʻau anttifungal

Lawe iā Atripla me kekahi mau lāʻau antifungal hiki ke hōʻemi i ka lāʻau. Hiki iā ia ke hoʻonui i kekahi mau hopena ʻaoʻao. ʻO nā laʻana o kēia mau lāʻau antifungal:

  • itraconazole
  • ketoconazole
  • posaconazole
  • vicalonazole

Nā lāʻau i hiki ke hoʻopili i ka hana o ka hakuʻala

Lawe iā Atripla me kekahi mau lāʻau e pili ana i ke ala o kāu mau puʻupaʻa e hiki ai ke hoʻonui i nā hopena o Atripla. Hiki i kēia ke alakaʻi i ka hoʻonui i nā hopena. Eia kekahi laʻana o kēia mau lāʻau:

  • kekahi mau lāʻau antiviral, e like me:
    • acyclovir
    • adefovir dipivoxil
    • pookela
    • ganciclovir
    • alohaa
    • kahooponopono
  • aminoglycosides, e like me gentamicin
  • nā lāʻau anti-inflammatory nonsteroidal (NSAIDs), e like me ka ibuprofen, piroxicam, a i ʻole ketorolac, ke hoʻohana pū ʻia a i ʻole nā ​​kiʻekiʻe.

Nā lāʻau i hiki ke hoʻēmi ʻia nā hopena

Nui nā lāʻau i hiki ke hoʻemi ʻia nā hopena ke lawe ʻia me Atripla. Eia kekahi laʻana o kēia mau lāʻau:

  • kekahi anticonvulsants, e like me:
    • carbamazepine
    • phenytoin
    • phenobarbital
  • kekahi antidepressants, e like me:
    • pāhoʻonui
    • sertraline
  • nā poloka ʻauʻa calcium, e like me:
    • diltiazem
    • felodipine
    • nicardipine
    • nifedipine
    • verapamil
  • kekahi statins (nā lāʻau kolesterol), e like me:
    • atorvastatin
    • pravastatin
    • simvastatin
  • kekahi mau lāʻau e hoʻoliʻiliʻi i ka hana o kāu ʻōnaehana pale, e like me:
    • cyclosporine
    • ʻākena
    • sirolimus
  • kekahi o nā pila kaohi hānau, e like me ka ethinyl estradiol / norgestimate
  • kekahi mau lāʻau i hoʻohana ʻia i loko o nā hāmeʻa kāohi implantable, e like me etonogestrel
  • liuliu
  • rifabutin
  • kekahi mau lāʻau e mālama pono i ka malaria, e like me:
    • artemether / lumefantrine
    • atovaquone / proguanil
    • methadone

Warfarin

Lawe iā Atripla me warfarin (Coumadin, Jantoven) hiki ke hana i ka warfarin ʻoi aku a emi paha ka hopena. Inā lawe ʻoe i warfarin, e kamaʻilio me kāu kauka e pili ana i nā hopena o ka lawe pū ʻana i kēia mau lāʻau.

Rifampin

Lawe iā Atripla me ka rifampin hiki ke hōʻemi iā Atripla. ʻO ia no ka mea hiki ke hōʻemi i ka nui o efavirenz i kou kino. ʻO Efavirenz kekahi o nā lāʻau i loaʻa ma Atripla.

Inā hoʻoholo kāu kauka pono ʻoe e lawe iā Atripla me ka rifampin, ʻōlelo paha lākou e lawe i kahi 200 keu i kēlā me kēia lā o efavirenz.

ʻO Atripla lāua ʻo Viagra

Hiki i ka Atripla ke hoʻonui i ka wikiwiki o ka hele ʻana o sildenafil (Viagra) i loko o kou kino. Hiki i kēia ke hōʻemi iā Viagra.

Inā makemake ʻoe e lawe iā Viagra i kou wā e mālama ai me Atripla, e kamaʻilio mua me kāu kauka. Hiki iā lākou ke aʻo iā ʻoe e pili ana inā ʻo Viagra ke koho maikaʻi loa nāu, a inā he lāʻau ʻē aʻe e ʻoi aku paha ka maikaʻi.

Atripla a me nā mea kanu a me nā mea hoʻohui

ʻO ka lawe ʻana iā St. John's wort me Atripla e hoʻoliʻiliʻi paha ka hopena iā Atripla. Inā makemake ʻoe e lawe pū i kēia huahana, e kamaʻilio mua me kāu kauka inā palekana ia.

A e ʻike pono e hōʻike i kāu kauka a me ka lāʻau lapaʻau i nā huahana kūlohelohe āu e lawe ai, ʻoiai ʻoe e manaʻo he kūlohelohe a palekana hoʻi lākou. Pākuʻi ʻia kēia i nā tī, e like me ka tī ʻōmaʻomaʻo, a me nā lāʻau kuʻuna, e like me ma-huang.

Atripla a me nā meaʻai

ʻO ka ʻai ʻana i ka grapefruit ʻoiai ʻoe e lawe iā Atripla hiki ke hoʻonui i nā kiʻekiʻe o ka lāʻau i kou kino. Hiki i kēia ke hoʻonui i nā hopena ʻaoʻao mai Atripla, e like me ka nausea a me ka luaʻi. Hōʻalo i ka ʻai ʻana i ka huaʻikuʻi a i ʻole ka wai momona i ka wā o kou mālama ʻana me Atripla.

Pehea e hana ai ʻo Atripla

ʻO ka maʻi HIV ka mea hōʻino i ka ʻōnaehana pale, ʻo ia ka pale o ke kino i nā maʻi. Ke hele a mālama ʻole ʻia ʻo HIV, lawe ia i nā pūnaewele ʻōnaehana pale i kapa ʻia he CD4 cells. Hoʻohana ka HIV i kēia mau hunaola e kope hou (e hana kope iā ia iho) a hohola i loko o ke kino.

Me ka ʻole o ka mālama ʻana, hiki i ka maʻi HIV ke lilo i maʻi ʻaʻai. Me ka maʻi AIDS, e nāwaliwali loa ka ʻōnaehana pale i hiki i ke kanaka ke hoʻomohala i nā kūlana ʻē aʻe, e like me ka niumonia a me ka lymphoma. ʻO ka hopena, hiki i ka maʻi AIDS ke hoʻopōkole i ke ola o ke kanaka.

ʻO Atripla kahi lāʻau hoʻohui i loaʻa i ʻekolu mau lāʻau antiretroviral. ʻO kēia mau lāʻau:

  • efavirenz, ʻo ia kahi mea non-nucleoside reverse transcriptase inhibitor (NNRTI)
  • emtricitabine, ʻo ia kahi mea hoʻohālikelike nucleoside analog huli transcriptase (NRTI)
  • tenofovir disoproxil fumarate, a he NRTI kekahi

Ke hana nei kēia mau lāʻau ʻekolu i ka hoʻōki ʻana i ka maʻi HIV mai ka hana kope ʻana. Hoʻoiho mālie kēia i ka viral viral a kekahi kanaka, ʻo ia ka nui o ka maʻi HIV i ke kino. Ke haʻahaʻa loa kēia pae i ka loaʻa ʻole o ka maʻi HIV i nā hopena hōʻike HIV, ua kapa ʻia ʻaʻole hiki ke ʻike ʻia. ʻO kahi ukana viral ʻike ʻole ʻia ka pahuhopu o ka mālama ʻana i ka maʻi HIV.

Pehea ka lōʻihi o ka hana?

No kēlā me kēia ʻano hoʻomaʻamaʻa HIV, me Atripla, he 8-24 mau pule ka lōʻihi o ke kau ʻana i kahi viral viral undetectable. ʻO kēia ka loaʻa ʻana o ke kanaka i ka maʻi HIV, akā aia ma kahi haʻahaʻa i ʻike ʻole ʻia e ka hoʻāʻo ʻana.

Pono wau e lawe i kēia lāʻau lōʻihi?

ʻAʻohe mea ola i kēia manawa no ka maʻi HIV. No laila, no ka mālama ʻana i ka amo viral HIV ma lalo o ka kaohi, pono mau ka hapanui o nā kānaka e lawe i kekahi ʻano o ka lāʻau HIV.

Inā hoʻoholo ʻoe a me kāu kauka e hana maikaʻi ana ʻo Atripla nāu, pono paha ʻoe e lawe i kahi wā lōʻihi.

Atripla a hāpai

Pono e hōʻalo i ka hāpai keiki i ka wā o ka mālama ʻana me Atripla, a ma ka liʻiliʻi he 12 mau pule ma hope o ka pau ʻana o ka lāʻau. ʻO kēia no ka mea hiki iā Atripla ke hōʻeha i kou hāpai ʻana.

Inā hāpai ʻoe a hoʻolālā paha ʻoe e hāpai, e kamaʻilio me kāu kauka. Hōʻike paha lākou i kahi lapaʻau ʻokoʻa no kāu HIV. A inā hāpai ʻoe i ka lawe ʻana iā Atripla, e kāhea koke aku i kāu kauka.

Inā lawe ʻoe iā Atripla i ka wā hāpai, noʻonoʻo paha ʻoe e hui pū me ka Antiretroviral Pregnancy Registry. Kuhi kēia papa inoa i ke olakino a me ka hāpai ʻana o ka poʻe i lawe i nā lāʻau antiretroviral ʻoiai hāpai. Hiki i kāu kauka ke haʻi hou aku iā ʻoe.

Atripla a me ka waiū hānai

Hōʻalo nā lāʻau i Atripla i ka waiū umauma. ʻAʻole pono ka poʻe e lawe nei iā Atripla i ka umauma, no ka mea lawe kā lākou keiki i ka lāʻau i loko o ka waiū umauma. Inā kū kēia, loaʻa paha i nā keiki nā hopena ʻaoʻao mai ka lāʻau, e like me ka maʻi diarrhea.

ʻO kekahi mea e noʻonoʻo ai e hele paha ʻo HIV i kahi keiki ma o ka waiū umauma. Ma ʻAmelika Hui Pū ʻIa, ua paipai nā Kikowaena no ka Makuahine a me Kāohi Kāohi (CDC) i ka poʻe me ka HIV e hōʻalo i ka hānai ʻana i ka waiū.

Eia nō naʻe, ke paipai nei ka World Health Organization (WHO) i ka hānai ʻana i ka waiū no nā poʻe me ka maʻi HIV i nā ʻāina ʻē aʻe he nui.

Nā nīnau e pili ana iā Atripla

Eia nā pane i kekahi o nā nīnau e nīnau pinepine ʻia e pili ana iā Atripla.

Hiki iā Atripla ke hoʻonāukiuki i ke kaumaha?

ʻAe, hiki i ka Atripla ke hoʻonāukiuki i ke kaumaha. I nā noiʻi hoʻokolohua, 9% o ka poʻe i lawe i ka lāʻau i hoʻomohala i ke kaumaha.

Inā ʻoe e ʻike i nā loli i kou ʻano ke lawe ʻoe iā Atripla, e kamaʻilio koke me kāu kauka. Hiki iā lākou ke hoʻololi i kāu olakino HIV, a hiki iā lākou ke hāʻawi i nā manaʻo kōkua'ē aʻe e hiki ke kōkua i ka hoʻomaha i kou kaumaha.

Hoʻola ʻo Atripla iā HIV?

ʻAʻole, ʻaʻohe mea ola i kēia manawa no ka maʻi HIV. Akā pono ka mālama ʻana i ka maʻi ma ka hopena o ka maʻi. ʻO kēia ka loaʻa ʻana o ke kanaka i ka maʻi HIV, akā aia ma kahi pae haʻahaʻa ʻaʻole i ʻike ʻia e ka hoʻāʻo ʻana. Manaʻo ka FDA i kēia manawa i kahi pae ʻike ʻole ʻia e kūleʻa maikaʻi.

Hiki iā Atripla ke pale aku iā HIV?

ʻAʻole, ʻaʻole ʻae ʻia ʻo Atripla no ka pale ʻana i ka maʻi HIV. ʻO ka lāʻau wale nō i ʻae ʻia e pale aku iā HIV ʻo Truvada, kahi i hoʻohana ʻia no ka prophylaxis pre-exposed (PrEP). Me PrEP, lawe ʻia ka lāʻau i mua o ke kū ʻana i ka maʻi HIV e kōkua ai i ka pale ʻana i ka maʻi.

ʻAʻole aʻo ʻia ʻo Atripla no kēia hoʻohana, ʻoiai aia i loko o nā lāʻau ʻelua i loaʻa i Truvada (emtricitabine a me tenofovir disoproxil fumarate). No laila, ʻaʻole pono e hoʻohana ʻia ʻo Atripla no kēia kumu.

ʻO ke kanaka i loaʻa ʻole ka maʻi HIV akā loaʻa ka manawa o ka ʻaelike ʻana e kamaʻilio me kā lākou kauka. Hiki iā lākou ke paipai i nā koho pale e like me PrEP a i ʻole prophylaxis ma hope o ka hōʻike ʻana (PEP). Hiki iā lākou ke ʻōlelo i nā hana pale ʻē aʻe, e like me ka hoʻohana mau ʻana i ka condom i ka wā wahine a anal paha.

He aha e hana ai inā wau e nalo i nā nui o Atripla?

Inā ʻoe e nalo i nā kaha he nui o Atripla, mai lawe i nā ʻōpala he nui no ka mea āu e nalo ai. Ma kahi o, e kamaʻilio koke me kāu kauka. E hōʻike lākou iā ʻoe i nā kaupaʻi aʻe e pono ai ʻoe e lawe.

He mea nui e lawe iā Atripla i kēlā me kēia lā. ʻO kēia no ka mea inā ʻoe e nalo i nā lāʻau, hiki i kou kino ke hoʻomohala i ka Atripla. Me ke kūpaʻa lāʻau, ʻaʻole hana hou kahi lāʻau e mālama i kekahi ʻano.

Akā inā ʻoe e haʻo wale i hoʻokahi mahele, i ka laulā, pono ʻoe e lawe i kēlā lāʻau i kou hoʻomanaʻo ʻana.

Nā ʻōlelo aʻoaʻo Atripla

Hele mai kēia lāʻau lapaʻau me nā ʻōlelo aʻoaʻo.

Ka ʻōlelo aʻoaʻo a FDA: Worsening of hepatitis B (HBV)

Aia kēia lāʻau i ka ʻōlelo aʻoaʻo a ka pahu. ʻO kēia ka ʻōlelo aʻo koʻikoʻi loa mai ka Food and Drug Administration (FDA). ʻO ka leka hoʻomaopopo e hōʻike i nā kauka a me nā mea maʻi e pili ana i nā hopena lāʻau e weliweli paha.

  • No ka poʻe e lawe nei iā Atripla a loaʻa ka maʻi HIV a me ka HBV, ke kāpae ʻana iā Atripla e alakaʻi i ka HBV ʻoi loa. Hiki i kēia ke alakaʻi i nā pilikia e like me ka hōʻino o ke ake.
  • Pono e hoʻāʻo nā mea maʻi āpau no ka HBV ma mua o ka hoʻomaka ʻana o ka mālama ʻana me Atripla. Eia kekahi, ʻaʻole pono ʻoe e haʻalele i ka lawe ʻana iā Atripla ke ʻole kāu kauka e haʻi aku iā ʻoe.
  • Inā loaʻa iā ʻoe ka maʻi HIV a me ka HBV a hoʻōki i ka lawe ʻana iā Atripla, pono ke kauka e nānā pono i kāu hana ate no kekahi mau mahina. Inā hōʻino kāu HBV, hiki i kāu kauka ke hoʻomaka iā ʻoe ma ka mālama ʻana iā HBV.

Nā ʻōlelo aʻoaʻo ʻē aʻe

Ma mua o ka lawe ʻana iā Atripla, e kamaʻilio me kāu kauka e pili ana i kāu mōʻaukala olakino. ʻAʻole kūpono paha ʻo Atripla iā ʻoe inā loaʻa iā ʻoe kekahi ʻano olakino. Pākuʻi ʻia kēia mau mea:

  • Hypersensitivity i Atripla a i ʻole nā ​​mea hana. Inā loaʻa iā ʻoe kahi hopena maʻi ʻino i ʻAtripla a i ʻole kekahi o nā lāʻau i loaʻa i loko, pono ʻoe e hōʻole i ka lawe ʻana iā Atripla. Inā kēnā kauka iā Atripla nāu, e haʻi pono iā lākou e pili ana i kāu hopena ma mua o kou hoʻomaka ʻana i ka lāʻau.

Kaha: No ka ʻike hou aku e pili ana i nā hopena maikaʻi ʻole o Atripla, e ʻike i ka ʻāpana "Nā ʻaoʻao" ma luna.

Hoʻopiʻi nui ʻo Atripla

ʻO ka lawe ʻana i ka nui o kēia lāʻau i hiki ke hoʻonui i kou makaʻi i nā hopena ʻino.

Nā hōʻailona overdose

ʻAʻole i hōʻike nā noiʻi hoʻokolohua a Atripla i ka mea e hiki ke hana inā lawe ʻia ka nui o ka lāʻau. Akā ua hōʻike ʻia nā noiʻi ʻē aʻe i ka lawe ʻana i ka efavirenz nui loa, kahi lāʻau i loaʻa ma Atripla, hiki ke hoʻonui i kekahi mau hopena o ka lāʻau. Pākuʻi ʻia kēia mau mea:

  • ʻūpā
  • pilikia hiamoe
  • huikau
  • nā ʻōlelo hoʻohiwahiwa
  • mimilo ʻili

He aha e hana ai inā he overdose

Inā lawe ʻoe ma mua o hoʻokahi papa Atripla i hoʻokahi lā, e haʻi i kāu kauka. A e ʻike pono e haʻi iā lākou e pili ana i nā loli i kāu hopena a i ʻole pehea e ʻike ai i ka nui.

Inā manaʻo ʻoe ua lawe nui ʻoe i ka Atripla, e kāhea i kāu kauka a i ʻole e ʻimi i ke alakaʻi mai ka ʻAmelika Hui Pū ʻIa Poison Control ma 800-222-1222 a i ʻole ma o kā lākou mea pono pūnaewele. Akā inā koʻikoʻi kāu mau ʻōuli, e kāhea iā 911 a i ʻole e hele koke i kahi lumi pilikia kokoke.

Pau Atripla

Ke haʻalele ʻia ʻo Atripla mai ka hale kūʻai lāʻau, e hoʻohui ka kauka i kahi lā palena pau i ka lepili ma ka ʻōmole. ʻO kēia lā he 1 mau makahiki ia mai ka lā i hāʻawi ʻia ai ka lāʻau.

ʻO ke kumu o kēlā mau lā palena pau e hōʻoia i ka hopena o nā lāʻau i kēia manawa. ʻO ke kūlana o ka Food and Drug Administration (FDA) i kēia manawa e hōʻalo i ka hoʻohana ʻana i nā lāʻau i make.

Pehea ka lōʻihi o ka maikaʻi o ka lāʻau e hiki ai ke hilinaʻi i nā kumu he nui, me ke ʻano a me kahi e mālama ʻia ai ka lāʻau. Pono e mālama ʻia nā pila Atripla i ka mahana wela, ma kahi o 77 ° F (25 ° C). E mālama pū ʻia lākou i loko o kā lākou ipu kumu, me ka uhi paʻa ʻana o ka uhi.

Inā loaʻa iā ʻoe kahi lāʻau i hoʻohana ʻole ʻia i hala i ka lā palena pau, e kamaʻilio me kāu kauka lāʻau e pili ana inā hiki paha iā ʻoe ke hoʻohana.

ʻO ka ʻike ʻoihana no Atripla

Hāʻawi ʻia ka ʻike aʻe no nā kauka lapaʻau a me nā ʻoihana ola.

Mekanism o ka hana

ʻO Atripla kahi papaha hui antiretroviral triple i loaʻa iā efavirenz, kahi non-nucleoside reverse transcriptase inhibitors (NNRTI), a me emtricitabine a me tenofovir disoproxil fumarate, ʻo ia nā nucleoside analog reverse transcriptase (NRTI).

Hoʻopili pū nā NNRTI a me nā NRTI i ka transcriptase hoʻohuli i ka HIV, kahi e hoʻōki ai i ka hoʻohuli ʻana o ka HIV RNA i ka HIV DNA. Eia nō naʻe, hana lākou i nā ʻāpana like ʻole o ka HIV hoʻohuli transcriptase enzyme.

Pharmacokinetics a me ka metabolism

Lawe ʻia ʻo Atripla ma kahi ʻōpū nele. Hoʻokomo koke ʻia nā lāʻau ʻekolu ma Atripla. Lawe ʻo Efavirenz i ka lōʻihi loa e kiʻi i nā pae kūmau (6-10 mau lā). ʻO ka hapalua o ke ola hoʻopau no nā lāʻau āpau ʻekolu e like me kēia:

  • efavirenz: 40-55 mau hola
  • emtricitabine: 10 mau hola
  • tenofovir disoproxil fumarate: 17 mau hola

ʻAʻole koi ʻia ʻo Atripla no ka hoʻohana ʻana i ka poʻe me ke akahai a ʻinoʻino paha o ka ate. Ma muli o ka hoʻopili ʻia ʻana o efavirenz e nā ʻenema ate (CYP P450), pono e hana me ka akahele i ka hoʻohana ʻana o Atripla i ka poʻe me nā ʻākea āpau.

ʻAʻole koi ʻia ka hoʻohana ʻana o Atripla i ka poʻe me ke ʻano kaulike a hōʻeha loa i ke kīʻaha (CrCl <50 mL / min).

Nā Kūʻai Kūʻai

ʻAʻole pono e hoʻohana ʻia ʻo Atripla i ka poʻe i loaʻa ka hopena maʻi maikaʻi ʻole iā efavirenz, ʻo ia kekahi o nā lāʻau i Atripla.

ʻAʻole pono e hoʻohana ʻia ʻo Atripla i ka poʻe e lawe pū nei i ka voriconazole a i ʻole elbasvir / grazoprevir.

Waihona

Pono e mālama ʻia ʻo Atripla ma ka mahana wela 77 ° F (25 ° C), paʻa paʻa ʻia i loko o kāna ipu kumu.

Hoʻolaha: Ua hana ʻo Nūhou Lapaʻau i kēia mau lā e hōʻoia i ka pololei, ka laulā, a me ka lā hou o nā ʻike āpau. Eia nō naʻe, ʻaʻole pono e hoʻohana i kēia ʻatikala i pani no ka ʻike a me ka mākaukau o kahi loea mālama ola laikini. E nīnau mau ʻoe i kāu kauka a i ʻole ʻoihana olakino ʻē aʻe ma mua o ka lawe ʻana i nā lāʻau. Hiki ke loli i ka ʻike o ka lāʻau i loko a ʻaʻole i manaʻo ʻia e uhi i nā hoʻohana a pau, nā kuhikuhi, ka mālama ʻana, nā ʻōlelo aʻoaʻo, nā launa lāʻau, nā hopena maʻi ʻaʻai, a me nā hopena maikaʻi ʻole. ʻO ka loaʻa ʻole o nā ʻōlelo aʻoaʻo a i ʻole nā ​​ʻike ʻē aʻe no kahi lāʻau i hāʻawi ʻia ʻaʻole ia e hōʻike i ka palekana o ka lāʻau a lāʻau paha i kūpono no nā mea maʻi āpau a i ʻole nā ​​hoʻohana kikoʻī āpau.

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