Nā helu ola a me Outlook no Acute Myeloid Leukemia (AML)

Anter

• He aha nā helu ola no ka AML?
• Nā keiki me AML
• He aha nā mea e hoʻohuli ai i ka helu ola?
• He aha ka hopena o ka makahiki i ka helu ola?
• He aha ka hopena o ka ʻano AML i ke ola ola?
• He aha ka hopena o ka pane ʻana i ka pane i ke ola ola?
• Pehea e hiki ai i ke kanaka ke ʻimi i ke kākoʻo?
• E nīnau i nā nīnau
• E ʻike i nā hui e hāʻawi i ke kākoʻo
• Hui i kahi hui kākoʻo
• E kiʻi aku i nā hoaaloha a me ka ʻohana
• E ʻike i nā ala leʻaleʻa e hoʻomaha ai i ke kaumaha

He aha ka leukemia myeloid koʻikoʻi (AML)?

ʻO ka leukemia myeloid ākea, a i ʻole AML, kahi ʻano maʻi ʻaʻai e hoʻopili i ka iwi iwi a me ke koko. ʻIke ʻia e nā ʻano inoa like ʻole, e like me ka leukemia myelogenous huehue a me ka leukemia non-lymphocytic maha. ʻO ka AML ka lua o ka leukemia maʻa mau i nā mākua.

Kāhea nā kauka iā AML "koʻikoʻi" no ka mea hiki ke holo wikiwiki i ke ʻano. ʻO ka huaʻōlelo ʻo “leukemia” e pili ana i nā maʻi ʻaʻai o ka iwi iwi a me nā aʻa koko. ʻO ka huaʻōlelo myeloid, a i ʻole myelogenous, pili i ke ʻano o ka pūnaewele e hoʻopili ai.

ʻO nā pūnaewele myeloid nā mea i mua o nā hunaola ʻē aʻe. ʻO ka maʻa mau o kēia mau hunaola e hoʻomohala i nā hunaola ʻulaʻula (RBC), platelet, a me nā ʻano kikoʻī o nā hunaola keokeo (WBC). Akā i ka AML, ʻaʻole hiki iā lākou ke hoʻomohala maʻamau.

Ke loaʻa ka AML o kekahi kanaka, hoʻololi a kā lākou mau hunaola myeloid a hana i nā hā leukemia. ʻAʻole holo kēia mau hunaola e like me ka hana ʻana o nā hunaola maʻamau. Hiki iā lākou ke mālama i ke kino mai ka hana ʻana i nā keena olakino olakino.

I ka hopena, e hoʻomaka kekahi i ka nele i nā RBC e halihali ana i ka oxygen, platelet e pale ai i ke kahe maʻalahi, a me nā WBC e pale i ke kino mai nā maʻi. ʻO ia no ka hana nui o ko lākou kino i ka hana ʻana i nā leukemikā blast cells.

Hiki ke make i ka hopena. Eia nō naʻe, no ka poʻe he nui, he maʻi hiki ke mālama ʻia ka AML.

He aha nā helu ola no ka AML?

ʻO ka holomua i ka mālama ʻana i ka maʻi ʻaʻai a me ka hoʻomaopopo ʻana o nā kauka i ka maʻi he ʻoi aku ka nui o nā poʻe e ola i ke ʻano i kēlā me kēia makahiki.

Kuhi kēlā me kēia makahiki i nā kauka he 19,520 paha ka poʻe i United States me AML. Kuhi ʻia he 10,670 mau make i kēlā me kēia makahiki no ka maʻi.

Loaʻa ka hapa nui o ka poʻe me AML i nā lāʻau chemotherapy. Pepehi wikiwiki kēia mau lāʻau i nā ʻāpana hoʻokaʻawale, e like me nā hunaola maʻi ʻaʻai. Hiki i ka Chemotherapy ke alakaʻi i ke kala, ʻo ia hoʻi ʻaʻole i loaʻa i kahi kanaka nā ʻōuli o ka maʻi a aia ka helu o ko lākou koko i kahi pae maʻamau.

Ma kahi o 90 pākēneka o ka poʻe me kahi ʻano AML i ʻike ʻia ma ke ʻano he leukemia promyelocytic koʻikoʻi (APL) e hele i ke kala ma hope o ka "induction" (puni mua) o ka chemo. ʻO kēia ka ʻōlelo a ka American Cancer Society (ACS). No ka hapa nui o nā ʻano AML, aia ka helu remit ma kahi o 67 pākēneka.

ʻO ka poʻe kahiko ma mua o 60 mau makahiki ʻaʻole lākou e pane maʻamau i ka lāʻau lapaʻau, me kahi o ka hapalua o lākou e hele ana i ke kala ma hope o ka hoʻokomo ʻana.

ʻO kekahi poʻe e hele i ke kala e noho i ke kala. Eia nō naʻe, no nā mea he nui, hiki i ka AML ke hoʻi i ka manawa.

ʻO ka helu ola ola ʻelima mau makahiki no AML he 27.4 pakeneka, e like me ka National Cancer Institute (NCI). ʻO kēia ke ʻano o nā ʻumi tausani mau ʻAmelika e noho nei me AML, kahi 27,4 pakeneka paha e noho nei ʻelima mau makahiki ma hope o kā lākou ʻike ʻia.

Nā keiki me AML

Ma ka laulā, ʻike ʻia nā keiki me ka AML ma mua o ka nui o ka makaʻu ma mua o nā mākua. Ma kahi o 85 a 90 paha pākēneka o nā keiki me AML e komo i ke kala ma hope o ke komo ʻana, e like me ka American Cancer Society. E hoʻi ʻo AML i kekahi mau hihia.

ʻO ka helu ola ola ʻelima mau makahiki no nā keiki me AML he 60 a 70 pakeneka.

He aha nā mea e hoʻohuli ai i ka helu ola?

Hoʻololi ka nānā a me ka wānana no ka AML. Manaʻo nā kauka i nā kumu he nui ke hāʻawi i kekahi i kahi wānana, e like me ka makahiki o ke kanaka a i ʻole ke ʻano o ka AML.

ʻO ka hapa nui o ia mea e pili ana i nā hopena a me nā anamanaʻo o nā hoʻāʻo ʻana o ke koko, nā noiʻi kiʻi ʻana, nā hōʻike o ka cerebrospinal fluid (CSF), a me nā biopsies o ka iwi iwi.

ʻO kekahi poʻe me kahi wānana maikaʻi ʻole e ola i nā makahiki hou aʻe ma mua o ka wānana a ke kauka ʻoiai ʻaʻole e ola lōʻihi kekahi.

He aha ka hopena o ka makahiki i ka helu ola?

ʻO ka makahiki waena o kekahi kanaka i ʻike ʻia me AML he 68 kona mau makahiki.

Hiki i ka makahiki ke lilo i kumu nui i ka hoʻoholo ʻana i ka pane o ka hoʻomaʻamaʻa AML. Ua ʻike nā kauka ʻo ka nui o ke ola no ka poʻe i ʻike ʻia me AML ʻoi aku ka maikaʻi o ka hoʻohiki no nā poʻe ma lalo o ka makahiki 60.

ʻO kēia no nā kumu he nui. ʻO kekahi poʻe i ʻoi aku i ka makahiki o 60 i loaʻa i nā kūlana maʻi ʻaʻohe paha i ke olakino maikaʻi. Hiki i kēia ke lilo i mea paʻakikī i ko lākou mau kino e lawelawe i nā lāʻau chemotherapy ikaika a me nā ʻano maʻi ʻaʻai ʻē aʻe e pili ana me AML.

Eia kekahi, he nui nā mākua me ka AML ʻaʻole i loaʻa ka lāʻau no ke ʻano.

Ua ʻike ʻia kahi noiʻi ma 2015 he 40 wale nō ka pākēneka o ka poʻe 66 a ʻoi i loaʻa ka chemotherapy i loko o ʻekolu mau mahina o ka hōʻailona. ʻOiai nā ʻokoʻa o ka pane lapaʻau ma waena o nā makahiki like ʻole (a i ʻole nā ​​cohorts), ua hoʻomaikaʻi ke ola holoʻokoʻa no nā poʻe ma waena o 65 a me 74 mau makahiki i loko o ʻekolu mau makahiki i hala, e like me kahi noiʻi 2011.

He aha ka hopena o ka ʻano AML i ke ola ola?

Hoʻokaʻawale pinepine nā kauka i nā ʻano like ʻole o ka AML e kā lākou hoʻololi ʻana o ka cell. ʻO kekahi o nā ʻano hoʻololi o ke kelepona i ʻike ʻia e pane maʻalahi i nā mālama ʻana. ʻO nā laʻana e pili ana i nā CEBPA mutated a me nā keena inv (16) CBFB-MYH11.

Hiki i kekahi hoʻololi ʻana o ke kelepona ke pale i ke kūpaʻa. ʻO nā laʻana me del (5q) a me inv (3) RPN1-EVI1. E haʻi aku kāu oncologist iā ʻoe i ke ʻano a i ʻole ke ʻano o ka mutation o ke kelepona i loaʻa iā ʻoe.

He aha ka hopena o ka pane ʻana i ka pane i ke ola ola?

ʻOi aku ka maikaʻi o ka pane ʻana o kekahi poʻe i ka lapaʻau ma mua o nā poʻe ʻē aʻe. Inā loaʻa i kekahi kanaka nā lāʻau chemotherapy a hoʻi ʻole kāna maʻi ʻaʻai i loko o ʻelima mau makahiki, manaʻo pinepine ʻia ua hoʻōla ʻia lākou.

Inā hoʻi mai ka maʻi ʻaʻai o kekahi kanaka a pane ʻole paha i nā mālama ʻana, ʻaʻole maikaʻi ka hopena o kā lākou lapaʻau ʻana.

Pehea e hiki ai i ke kanaka ke ʻimi i ke kākoʻo?

Nānā ʻole i ka wānana, hiki i kahi hōʻailona AML ke hana i nā manaʻo o ka makaʻu, ka hopohopo, a me ka maopopo ʻole. Maluhia paha ʻoe ma hea e huli a ʻimi i ke kākoʻo.

Ke hōʻike nei kahi hōʻailona maʻi ʻaʻai i ka manawa kūpono e ulu kokoke ai ʻoe i ka poʻe kokoke iā ʻoe a loiloi pehea e hiki ai iā ʻoe ke ola i kahi ola āu e leʻaleʻa ai.

Eia kekahi mau ʻōlelo aʻoaʻo e kōkua iā ʻoe e hoʻokele i kēia kuhi a me ka lāʻau.

E nīnau i nā nīnau

He mea nui e hoʻomaopopo ʻoe i kou ʻano. Inā loaʻa kekahi mea āu e kānalua ʻole ai e pili ana i kāu kuhi, lapaʻau, a wānana paha, e nīnau i kāu kauka.

Hiki i nā laʻana o nā nīnau ke nīnau "He aha kaʻu mau koho lapaʻau?" a "He aha kaʻu e hana ai e pale aku iā AML mai ka hoʻi mai?"

E ʻike i nā hui e hāʻawi i ke kākoʻo

Hāʻawi nā hui e like me ka American Cancer Society (ACS) i kekahi mau lawelawe kākoʻo.

Hoʻopili kēia i ka hoʻonohonoho ʻana i nā holo i ka lāʻau lapaʻau a me ke kōkua ʻana iā ʻoe e ʻike i nā limahana kōkua, e like me nā dietitians a i ʻole nā ​​limahana kaiaulu.

Hui i kahi hui kākoʻo

ʻO nā hui kākoʻo kahi ala maikaʻi loa e hālāwai me nā poʻe e hele nei i nā ʻano like me ʻoe. ʻO ka ʻike ʻana i nā kūleʻa a me ka noʻonoʻo o nā poʻe ʻē aʻe hiki ke kōkua iā ʻoe e ʻike ʻaʻole ʻoe hoʻokahi.

Ma waho aʻe o nā kumuwaiwai e like me ka ACS a me ka LLS, hiki i kāu oncologist a i ʻole ka haukapila kūloko ke hāʻawi i nā hui kākoʻo.

E kiʻi aku i nā hoaaloha a me ka ʻohana

Nui nā hoaaloha a me nā lālā o ka ʻohana e makemake e kōkua. E hāʻawi iā lākou i nā meaʻai ma o ka lawelawe e like me Meal Train a hoʻolohe wale paha i kāu mau hopohopo. Hiki i ka wehe ʻana i nā poʻe ʻē aʻe ke kōkua iā ʻoe e mālama i kahi manaʻo maikaʻi.

E ʻike i nā ala leʻaleʻa e hoʻomaha ai i ke kaumaha

Nui nā mākeke no ʻoe e hōʻoluʻolu i ke koʻikoʻi a me ka hopohopo i kou ola. ʻO ka noʻonoʻo a mālama ʻana paha i kahi puke pai a blog paha kekahi mau laʻana. Hoʻohui, uku liʻiliʻi lākou e lawe a hoʻomau.

Ke loaʻa nei kahi puka āu e leʻaleʻa ai hiki ke hana i nā mea kupanaha no kou noʻonoʻo a me kou ʻuhane.