Hoʻoikaika ACTH

Anter

• Pehea e hana ai i ka hōʻike ACTH
• No ke aha e hana ʻia ai ka hōʻike ACTH
• He aha ka hopena o ka hopena o ka hopena ʻo ACTH
• Nā pilikia o kahi hōʻike ACTH
• He aha ka mea e manaʻo ai ma hope o kahi hōʻike iā ACTH

He aha ka hoʻāʻo ʻo ACTH?

Adrenocorticotropic hormone (ACTH) kahi hormone i hana ʻia i loko o ka mua, a i mua paha, pituitary gland i ka lolo. ʻO ka hana a ACTH ka hoʻoponopono ʻana i nā pae o ka steroid hormon cortisol, i hoʻokuʻu ʻia mai ka adrenal gland.

ʻIke ʻia ʻo ACTH ma ke ʻano he:

• hōmona adrenocorticotropic
• serum adrenocorticotropic hōmona
• mahalo nui loa iā ACTH
• lāʻau pākuʻi
• cosyntropin, kahi ʻano lāʻau o ACTH

Ana kahi hōʻike ACTH i nā pae o ka ACTH a me ka cortisol i loko o ke koko a kōkua i kāu kauka e ʻike i nā maʻi e pili ana i ka nui a i ʻole ka liʻiliʻi o ka cortisol i ke kino. ʻO nā kumu kūpono o kēia mau maʻi me:

• kahi maʻi pituitary a adrenal paha
• he maʻi pituitary tumor
• he tumora adrenal
• he puʻupuʻu puʻupuʻu

Pehea e hana ai i ka hōʻike ACTH

E ʻōlelo paha kāu kauka iā ʻoe ʻaʻole e lawe i nā lāʻau steroid i mua o kāu hōʻike. Hiki i kēia mau mea ke hoʻopili i ka pololei o nā hopena.

Hana pinepine ʻia ka hōʻike ma ke kakahiaka. ʻOi aku ka kiʻekiʻe o nā pae ʻo ACTH ke ala ʻoe. E hoʻonohonoho paha kāu kauka i kāu hōʻoia no ke kakahiaka nui.

Hōʻaʻo ʻia nā pae ʻo ACTH me ka hoʻohana ʻana i kahi laʻana koko. Lawe ʻia kahi laʻana koko e ke kiʻi ʻana i ke koko mai kahi aa, maʻa mau o loko o ka kuʻe lima. ʻO ka hāʻawi ʻana i kahi hāpana koko e pili ana i kēia mau hana:

1. Hoʻomaʻemaʻe mua kahi mea lawelawe olakino i ka pūnaewele me kahi antiseptic e pepehi i nā mikamina.
2. A laila, e hoʻopili lākou i kahi kaula elastis a puni kou lima. ʻO kēia ke kumu e pehu ai ke aa koko.
3. E hoʻokomo mālie lākou i kahi nila o ke kui kele i loko o kou aa a hōʻiliʻili i kou koko i ka pūmole syringe.
4. Ke piha ka paipu, hemo ka nila. Lawe ʻia ke kāʻei elastis, a uhi ʻia ka pūnaewele puncture me ka gauze sterile e hoʻōki i ke kahe ʻana o ke kahe.

No ke aha e hana ʻia ai ka hōʻike ACTH

Hiki paha i kāu kauka ke kauoha i kahi hoʻokolohua koko ACTH inā loaʻa iā ʻoe nā ʻōuli o ka nui a i ʻole liʻiliʻi paha o ka cortisol. Hiki ke loli ākea kēia mau ʻōuli mai kekahi kanaka a i kekahi kanaka a pinepine i hōʻailona o nā pilikia olakino hou aʻe.

Inā loaʻa iā ʻoe kahi pae kiʻekiʻe cortisol, loaʻa paha iā ʻoe:

• momona
• he helehelena poepoe
• lahilahi, ʻili lahilahi
• nā laina poni ma ka ʻōpū
• nā mākala nāwaliwali
• huehue
• he lauoho hoʻonui ʻia
• kahe koko kiʻekiʻe
• pae pae potassium haʻahaʻa
• pae kiʻekiʻe bikarbonate kiʻekiʻe
• pae glucose kiʻekiʻe
• diabetes

ʻO nā ʻōuli o ka liʻiliʻi cortisol me:

• nā mākala nāwaliwali
• luhi
• Kaumaha emi
• hoʻonui i ka pigmentation ʻili ma nā wahi i kū ʻole i ka lā
• he nalowale o ka makemake
• haʻahaʻa haʻahaʻa haʻahaʻa
• haʻahaʻa pae kō glucose
• pae paʻakai haʻahaʻa
• kiʻekiʻe pae potasiuma
• kiʻekiʻe pae kalipuna

He aha ka hopena o ka hopena o ka hopena ʻo ACTH

ʻO nā waiwai maʻamau o ka ACTH he 9 a 52 mau kiʻi ma ka milliliter. Hiki ke hoʻololi iki i nā pae maʻamau maʻamau e pili ana i ka hale hana. E wehewehe kāu kauka i kāu mau hopena hōʻike iā ʻoe.

ʻO kahi pae kiʻekiʻe o ACTH he hōʻailona paha o:

• Maʻi ʻo Addison
• hyperplasia adrenal
• Maʻi ʻo Cushing
• kahi tumo ectopic e hana ana iā ACTH
• adrenoleukodystrophy, ka mea kākaʻikahi loa
• ʻO Nelson's syndrome, he mea liʻiliʻi loa ia

ʻO kahi pae haʻahaʻa o ACTH he hōʻailona paha o:

• ʻōiwi adrenal
• exogenous Cushing's syndrome
• hypopituitarism

Lawe i nā lāʻau steroid hiki ke hoʻohaʻahaʻa i nā pae haʻahaʻa o ACTH, no laila e ʻike pono i kāu kauka inā ʻoe ma nā steroid.

Nā pilikia o kahi hōʻike ACTH

ʻAno maikaʻi ʻia nā hoʻokolohua koko. ʻOi aku ka liʻiliʻi a i ʻole ka nui o nā uaua o kekahi poʻe, ʻoi aku ka paʻakikī o ka lawe ʻana i kahi laʻana koko. Eia nō naʻe, kākaʻikahi nā kamepiula e pili ana i nā hoʻokolohua koko e like me ka hoʻāʻo ʻana o ka hormone ACTH.

ʻO nā pilikia maʻamau o ke kaʻi ʻia ʻana o ke koko:

• kahe nui ke koko
• ʻālohilohi a maʻule paha
• hematoma, a i ʻole ke kōkō ʻana o ke koko ma lalo o ka ʻili
• maʻi ma ka pūnaewele

He aha ka mea e manaʻo ai ma hope o kahi hōʻike iā ACTH

ʻIke i nā maʻi ʻo ACTH hiki ke lilo i paʻakikī. Pono paha kāu kauka e kauoha hou aku i nā hoʻokolohua hoʻokolohua a hana i kahi hoʻokolokolo kino ma mua o ka hiki iā lākou ke hana i kahi hōʻailona.

No ka hūnā ʻana ʻo ACTH, hōʻike mau ʻia ke ʻoki. I kekahi manawa, hiki ke hoʻohana i nā lāʻau e like me cabergoline e normalize ai i nā pae cortisol. Hypercortisolism ma muli o ka adrenal hikoko pono nā ʻoki pū kekahi.