Mea Kākau: Clyde Lopez
Lā O Ka Hana: 23 Iulai 2021
HōʻAno Hou I Ka Lā: 15 Nowemapa 2024
Anonim
Pharmacology 880 c Anti Viral AIDS HIV Treatment PI Protease Inhibitors Indinavir IDV Nelfinavir NFV
Wikiō: Pharmacology 880 c Anti Viral AIDS HIV Treatment PI Protease Inhibitors Indinavir IDV Nelfinavir NFV

Anter

Hoʻohana ʻia ʻo Nelfinavir me nā lāʻau ʻē aʻe e mālama ai i ka maʻi maʻi (HIV) maʻi kanaka. Aia ʻo Nelfinavir i kahi papa o nā lāʻau i kapa ʻia nā protease inhibitors. Hana ia ma ka hoʻemi ʻana i ka nui o ka maʻi HIV i loko o ke koko. ʻOiai ʻaʻole mālama ʻo nelfinavir i ka maʻi HIV, hoʻoliʻiliʻi paha ia i kou manawa o ka hoʻomohala ʻia ʻana o ka maʻi maʻi maʻi (AIDS) a me nā maʻi e pili ana i ka maʻi HIV e like me nā maʻi nui a i ʻole ke kanesa. ʻO ka lawe ʻana i kēia mau lāʻau me ka hana palekana ʻana i ka moekolohe a me ka hoʻololi ʻana i nā ʻano nohona ʻē aʻe e hōʻemi paha i ka lawe ʻana i ka maʻi HIV i kekahi poʻe ʻē aʻe.

Hele mai ʻo Nelfinavir ma ke ʻano he papa a me ka pauka e lawe ai i ka waha. Lawe ʻia ia i ʻelua a ʻekolu mau manawa i ka lā me ka meaʻai. Lawe iā nelfinavir ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pololei iā nelfinavir e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.


Inā hiki ʻole iā ʻoe ke ale i ka pā, hiki paha iā ʻoe ke waiho i loko o ke kīʻaha a hoʻoheheʻe ʻia i loko o kahi wai liʻiliʻi. Hui pono i ka wai, a inu koke. E holoi i ke aniani me ka wai hou a ale i ka hui āpau e ʻike pono ua lawe ʻoe i nā lāʻau āpau.

Hiki ke hoʻohui ʻia i ka pauka waha Nelfinavir i ka wai, ka waiū, ka haʻilula, ka waiū soy, a i ʻole nā ​​mea hoʻopili meaʻai. Hoʻohui maikaʻi, a inu koke i nā wai āpau i mea e lawe ai i ka piha piha. Ke haʻi aku nei kāu lepili kuhikuhi iā ʻoe i ka nui o nā scoops o nelfinavir pauka e hoʻohui i ka wai. Inā ʻaʻole lawe koke ʻia ka hui ʻana pono e waiho ʻia i loko o ka pahu hau a lawe ʻia i loko o 6 mau hola. Mai hoʻohui i ka paula wahahehe hidfinavir me ka meaʻai acidic a i ʻole ka wai ʻalani (wai ʻalani, wai ʻāpala, a me nā mea ʻono apple). Mai hoʻohui i ka nelfinavir me ka wai i loko o ka ipu kumu.

Mālama ʻo Nelfinavir i ka maʻi HIV akā ʻaʻole ia e hoʻōla iā ia. E hoʻomau i ka lawe nelfinavir ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana iā nelfinavir me ke kamaʻilio ʻole ʻana me kāu kauka. Inā kū ʻoe i ka lawe ʻana i nā nelfinavir a i ʻole lele i nā lāʻau, malia paha eʻoi aku ka maikaʻi o kou maʻi a lilo i pale i nā lāʻau.


E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kuhi ʻia kēia lāʻau i kekahi manawa no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana iā nelfinavir,

  • e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka nelfinavir, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o ka papa nelfinavir a i ʻole ka pauka. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka inā lawe ʻoe i alfuzosin (Uroxatral); amiodarone (Cordarone, Nexterone, Pacerone); cisapride (Propulsid; ʻaʻole loaʻa i ka U.S.); nā lāʻau lapaʻau ergot-type e like me bromocriptine (Cycloset, Parlodel), dihydroergotamine (D.H.E. 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (Ergomar, ma Cafergot, ma Migergot), a me methylergonovine (Methergine); lovastatin (Altoprev); lurasidone (Latuda); midazolam (Versed) e ka waha; pimozide (Orap); quinidine (i Nuedexta); rifampin (Rimactane, Rifadin, ma Rifater, ma Rifamate); sildenafil (ʻo ka inoa Revatio wale nō i hoʻohana ʻia no ka maʻi puʻupuʻu); simvastatin (Zocor, i Vytorin); St. John's wort; and triazolam (Halcion). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe iā nelfinavir inā ʻoe e lawe i hoʻokahi a ʻoi paha o kēia mau lāʻau.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, a me nā mea hoʻopihaʻaiʻai āu e lawe nei a hoʻolālā paha e lawe. E hōʻoia e haʻi i kekahi o kēia mau mea: anticoagulants ('nā mea hōʻemi koko') e like me warfarin (Coumadin, Jantoven); azithromycin (Azasite, Zithromax, Zmax); bosentan (Tracleer); kekahi mau lāʻau kalika e pale ana i nā lāʻau e like me amlodipine (Norvasc, ma Prestalia, ma Twynsta, a me nā mea ʻē aʻe), felodipine, isradipine, nicardipine (Cardene), nifedipine (Adalat, Afeditab, Procardia), nimodipine (Nymalize), a me nisoldipine (Sular); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, a me nā mea ʻē aʻe); kekahi mau lāʻau hoʻohaʻahaʻa kolesterol (statins) e like me atorvastatin (Lipitor, ma Caduet) a me rosuvastatin (Crestor); colchisin (Colcrys, Mitigare); delavirdine (Mea kākau); fluticasone (Flonase, Flovent; i Advair); indinavir (Crixivan); nā lāʻau e kāohi i ka ʻōnaehana pale e like me cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune, Torisel), a me tacrolimus (Astagraf XL, Prograf); methadone (Dolophine, Methadose); nevirapine (Viramune); kekahi mau mea kāpae phosphodiesterase (PDE-5 mea kāohi) i hoʻohana ʻia no ka hana erectile e like me sildenafil (Viagra), tadalafil (Adcirca, Cialis), a me vardenafil (Levitra); phenobarbital; phenytoin (Dilantin, Phenytek); nā mea pale proton-pump e like me esomeprazole (Nexium), lansoprazole (Prevacid), omeprazole (Prilosec), pantoprazole (Protonix), a me rabeprazole (AcipHex); quetiapine (Seroquel); rifabutin (Mycobutin); ritonavir (Norvir, ma Kaletra, ma Viekira Pak); salmeterol (Serevent, ma Advair); saquinavir (Hoʻokele); a trazodone. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me nelfinavir, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
  • inā ʻoe e lawe ana i ka didanosine (Videx), lawe ia i hoʻokahi hola ma mua a ʻoi aku paha ma mua o 2 mau hola ma hope o nelfinavir.
  • e haʻi i kāu kauka inā e lawe ana ʻoe i nā lāʻau kaohi hānau. Hiki iā Nelfinavir ke hoʻoliʻiliʻi i ka hopena o nā mea pale waha. E hoʻohana ʻoe i kahi hana ʻē aʻe o ka kaohi hānau ʻana ke lawe ʻoe i kēia lāʻau. E kamaʻilio me kāu kauka e pili ana i ka kaohi hānau ke lawe iā nelfinavir.
  • e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ʻaʻai, hemophilia (kahi hui o nā maʻi hoʻokahe hoʻoilina i hiki ʻole ke hiki i ke kōpē ke maʻamau), a i ʻole nā ​​maʻi ate.
  • E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana iā nelfinavir, e kāhea i kāu kauka. ʻAʻole pono ʻoe e hānai waiū inā loaʻa ka maʻi HIV a ke lawe nei iā nelfinavir.
  • inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe nei ʻoe i ka nelfinavir.
  • pono ʻoe e makaʻala e hoʻonui a neʻe paha kou momona o ke kino i nā wahi like ʻole o kou kino, e like me kou kua i luna, ʻāʻī ('buffalo hump'), nā umauma, a puni kou ʻōpū. ʻIke paha ʻoe i ka nalo ʻana o ka momona o ke kino mai kou alo, mau wāwae, a me kou mau lima.
  • pono ʻoe e ʻike e ʻike paha ʻoe i ka hyperglycemia (hoʻonui i kāu kō kō) ʻoiai ʻoe e lawe nei i kēia lāʻau, ʻoiai inā ʻaʻohe ou diabetes. E haʻi koke i kāu kauka inā loaʻa iā ʻoe kekahi o nā ʻōuli aʻe ke lawe nei ʻoe i ka nelfinavir: make wai loa, mimiki pinepine, pololi loa, ʻike maka ʻole ʻia, a nāwaliwali paha. He mea nui ia e kāhea aku i kāu kauka ke loaʻa koke iā ʻoe kekahi o kēia mau ʻōuli, no ka mea, ʻaʻole mālama ʻia ke kō koko kiʻekiʻe e mālama ʻia ai i kahi ʻano koʻikoʻi i kapa ʻia ʻo ketoacidosis. Lilo paha ʻo Ketoacidosis i mea hoʻoweliweli i ke ola ke mālama ʻole ʻia ia i ka wā mua. ʻO nā ʻōuli o ketoacidosis e komo pū me ka waha maloʻo, kahe a me ka luaʻi, ka hanu o ka hanu, ka hanu e ʻaʻala i ka hua, a me ka emi o ka ʻike.
  • inā he phenylketonuria ʻoe (PKU, kahi ʻano hoʻoilina e pono ai e ukali ʻia kahi papaʻai kūikawā e pale ai i ka noʻonoʻo noʻonoʻo), pono ʻoe e ʻike i ka momona o nelfinavir pauka waha me ka aspartame e hana ai i ka phenylalanine.
  • pono ʻoe e ʻike ʻoiai ʻoe e lawe nei i nā lāʻau e mālama ai i ka maʻi HIV, e ikaika paha kou ʻōnaehana pale a hoʻomaka e hakakā i nā maʻi ʻē aʻe i loko o kou kino. Hiki iā ʻoe ke hoʻomohala i nā ʻōuli o kēlā mau maʻi. Inā loaʻa iā ʻoe nā hōʻailona hou a pōʻino paha i kēlā me kēia manawa i kāu mālama ʻana me nelfinavir, e haʻi pono i kāu kauka.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.


E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Nelfinavir i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • pāhoehoe
  • nausea
  • ʻenekini
  • ʻeha ka ʻōpū
  • nalo ʻai ʻole
  • hūwī

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

  • hives
  • ʻūlili
  • pilikia i ka hanu ʻana a i ʻole ke ale ʻana

Loaʻa i loko o Nelfinavir kahi kemika i loaʻa i kumu no ka maʻi ʻaʻai i loko o nā holoholona laboratory. Ua noi aku ka Food and Drug Administration (FDA) i ka mea hana e hana i nā loli i ke ʻano o ka nelfinavir e hoʻoliʻiliʻi ai i ka nui o kēia kemika i nā huahana nelfinavir. ʻAʻole ʻike ʻia ka makaʻu i nā kānaka akā kiʻekiʻe paha i nā keiki a me nā wahine hāpai. E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka lawe ʻana iā nelfinavir.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua. Ma hope o ka hoʻohui ʻia ʻana o ka paula nelfinavir i ka wai, mālama ʻia ka hui ʻana ma ke ana wela no 6 mau hola.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i kāu pane iā nelfinavir.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

E mālama i kahi lako o nelfinavir ma ka lima. Mai kali a hiki i ka pau ʻana o kāu lāʻau e hoʻopiha hou i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • Viracept®
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