Evinacumab-dgnb ka pahu kui

Anter

• Ma mua o ka loaʻa ʻana o evinacumab-dgnb,
• Hiki i nā Evinacumab-dgnb ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

Hoʻohana ʻia ʻo Evinacumab-dgnb i hui pū ʻia me nā hana ʻē aʻe e hōʻemi i ka nui o ka lipoprotein (LDL) kolamu haʻahaʻa ('kolesterol maikaʻi') a me nā mea momona ʻē aʻe i loko o ke koko i nā mākua a me nā keiki he 12 mau makahiki a ʻoi paha i loaʻa i ka hyperkolesterolemia ʻohana homozygous. (HoFH; kahi ʻano hoʻoilina kahi hiki ʻole ke hoʻoneʻe ʻia ka cholesterol mai ke kino maʻamau). Aia ʻo Evinacumab-dgnb i loko o ka papa o nā lāʻau i kapa ʻia angiopoietin-like protein 3 (ANGPTL3) mea pale monoclonal antibodies. Hana ia ma ka hoʻemi ʻana i ka hana ʻana o ka LDL cholesterol a hoʻonui i ka haki ʻana o ka LDL cholesterol a me nā mea momona ʻē aʻe i loko o ke kino.

ʻO ka hōʻuluʻulu ʻana o ka cholesterol a me nā momona ma nā paia o kou aʻa (kahi hana i ʻike ʻia ʻo atherosclerosis) e hoʻemi ana i ke kahe o ke koko a, no laila, hāʻawi ka oxygen i kou puʻuwai, lolo, a me nā ʻāpana ʻē aʻe o kou kino Hiki ke kōkua i ka hoʻohaʻahaʻa ʻana i ke kiʻekiʻe o kou koko a me nā momona ke pale aku i nā maʻi puʻuwai, angina (ʻeha o ka umauma), nā hahau, a me nā hōʻeha puʻuwai.

Hele mai ʻo Evinacumab-dgnb ma ke ʻano he hopena (wai) e kāwili ʻia me ka wai a injected me ka lohi i loko o kahi aa i 60 mau minuke e ke kauka a kahu hānai paha. Hāʻawi pinepine ʻia hoʻokahi manawa i kēlā me kēia 4 pule.

Hiki i ke kuʻi ʻana ʻo Evinacumab-dgnb ke hana i nā hopena koʻikoʻi i ka wā o ka hoʻokomo ʻana o ka lāʻau. E nānā pono kahi kauka a kahu hānai paha iā ʻoe ke loaʻa iā ʻoe ka lāʻau. E haʻi koke i kāu kauka a kahu hānai paha inā ʻike ʻoe i kekahi o nā ʻōuli ma hope a i ʻole a ma hope paha o ke kuʻi ʻana: ka liʻiliʻi o ka hanu; ʻūhā; ʻehu; hives; ʻumeʻume; ʻūpā; nāwaliwali o nā mākala; kuni; nausea; piko o ka ihu; aiʻole ka pehu ʻana o ka maka, puʻu, alelo, lehelehe, a i ʻole nā ​​maka.

Pono paha kāu kauka e hoʻolohi i kāu infusion a hoʻopau paha i kāu lāʻau inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. E pono e haʻi aku i kāu kauka i kou ʻano i kou wā e mālama ai me evinacumab-dgnb.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o evinacumab-dgnb,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka evinacumab-dgnb, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o ka inikopa evinacumab-dgnb. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe.
• e haʻi i kāu kauka inā hāpai ʻoe, a i ʻole hoʻolālā e hāpai. Pono paha ʻoe e lawe i kahi hōʻike hāpai ma mua o ka hoʻomaka ʻana o ka lāʻau ʻana me evinacumab-dgnb. ʻAʻole pono ʻoe e hāpai i ka wā o kāu mālama ʻana me ka inikua evinacumab-dgnb. Pono ʻoe e hoʻohana i ka kaohi hānau pono e pale i ka hāpai ʻana i ka wā o kāu mālama ʻana me ka injection evinacumab-dgnb a no 5 mau mahina ma hope o kāu hopena hope loa. Inā hāpai ʻoe i ka loaʻa ʻana iā evinacumab-dgnb, e kāhea koke i kāu kauka.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū.

ʻAi i kahi papaʻai momona momona, momona momona. E mālama pono i nā hana hoʻoikaika kino a me nā papa kuhikuhi papaʻai i hana ʻia e kāu kauka a i ʻole dietitian. Hiki iā ʻoe ke kipa aku i ka National Cholesterol Education Program (NCEP) pūnaewele no ka ʻike pili i ka papaʻai ma: http://www.nhlbi.nih.gov/health/public/heart/chol/chol_tlc.pdf.

Kāhea koke i kāu kauka inā ʻaʻole hiki iā ʻoe ke mālama i kahi manawa e loaʻa ai kahi lāʻau o ka inikū evinacumab-dgnb.

Hiki i nā Evinacumab-dgnb ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ihu ihope
• paheʻe ihu
• eha ka 'ā'ī
• nā ʻōuli like flu
• eha ka 'ā'ī
• ʻūpā
• nausea
• ʻeha ma nā wāwae a i ʻole nā ​​lima
• hoʻemi ikehu

Hiki i nā Evinacumab-dgnb ke hana i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino iā evinacumab-dgnb.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Evkeeza^®