ʻO Pralsetinib

Anter

• Ma mua o ka lawe ʻana i ka pralsetinib,
• Hoʻokumu paha ʻo Pralsetinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i PRECAUTIONS SPECIAL, e kelepona koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ʻo Pralsetinib e mālama i kekahi ʻano maʻi ʻaʻai liʻiliʻi liʻiliʻi ʻole (NSCLC) i nā mākua i pāhola ʻia i nā ʻāpana ʻē aʻe o ke kino. Hoʻohana ʻia ia e mālama i kekahi ʻano o ka maʻi ʻaʻai thyroid i nā mākua a me nā keiki he 12 mau makahiki a ʻoi paha e ʻino ana a i hele paha i nā ʻāpana ʻē aʻe o ke kino. Hoʻohana ʻia ʻo Pralsetinib e mālama i kekahi ʻano o ka maʻi ʻaʻai thyroid i nā mākua a me nā keiki he 12 mau makahiki a ʻoi paha e ʻino ana a i ʻole pālahalaha ʻia i nā ʻāpana ʻē aʻe o ke kino a ʻaʻole hiki ke mālama ʻia me ka iodine radioactive. Aia ʻo Pralsetinib i kahi papa o nā lāʻau i kapa ʻia ʻo nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o kekahi mea kūlohelohe e pono ai e kōkua i nā hunaola maʻi ʻaʻai e hoʻonui.

Hele mai ʻo Pralsetinib ma ke ʻano he capsule e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i kēlā me kēia lā ma ka ʻōpū hakahaka, ma ka liʻiliʻi he 2 mau hola ma mua a ma ka liʻiliʻi 1 hola ma hope o ka pāʻina ʻana. E lawe i ka pralsetinib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka pralsetinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Inā luaʻi ʻoe ma hope o ka lawe ʻana i ka pralsetinib, mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau a i ʻole manawa kūmau a paʻa mau paha i kāu lāʻau inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. E haʻi pono i kāu kauka i kou ʻano i kou wā e mālama ai me pralsetinib.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka pralsetinib,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka pralsetinib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā capsule pralsetinib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E ʻōlelo pono i kekahi o nā mea aʻe: nā lāʻau antifungal me itraconazole (Onmel, Sporanox) a me ketoconazole; clarithromycin (i Biaxin); kekahi mau lāʻau HIV e like me efavirenz (Sustiva, i Atripla, Symfi), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, ma Kaletra, Viekira Pak), a me saquinavir (Invirase); oxcarbazepine (Oxtellar XR, Trileptal); phenobarbital; phenytoin (Dilantin, Phenytek); pioglitazone (Actos, ma Oseni, Duetact); rifabutin (Mycobutin); a me rifampin (Rifadin, Rimactane, ma Rifater). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i nā pilikia hanu a i ʻole nā ​​pilikia ʻē aʻe ma mua o ka maʻi ʻaʻa maʻi, nā kahe koko, ke koko kiʻekiʻe, a i ʻole nā ​​maʻi ate.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a inā ʻoe e hoʻolālā i kahi keiki i kahi keiki. Hoʻopilikia paha ʻo Pralsetinib i ka hana o nā mea pale hormonal (nā lāʻau kaohi hānau, nā pāhoʻi, nā apo, nā implants, a i ʻole nā ​​injection), no laila ʻaʻole pono ʻoe e hoʻohana i kēia mau mea ma ke ʻano he ʻano hana wale no kou kaohi hānau i kāu wā e mālama ai. Pono ʻoe e hoʻohana i kahi kaohi hānau ʻole hormonal e like me ke ʻano pale (kahi mea e ālai i ka sperm mai ke komo ʻana i ka pūpū e like me ka condom a i ʻole diaphragm) E noi i kāu kauka e kōkua iā ʻoe e koho i kahi hana o ka kaohi hānau e holo pono nāu. Inā he wahine ʻoe, pono ʻoe e hoʻokolohua hāpai ma mua o kou hoʻomaka ʻana i ka lāʻau, a pono ʻoe e hoʻohana i ka kaohi hānau ʻole hormonal e pale ai i ka hāpai ʻana i kāu wā lapaʻau a no 2 mau pule ma hope o kāu hopena hope loa. Inā he kāne ʻoe a hiki i kāu pakanā ke hāpai, pono ʻoe e hoʻohana i ka kaohi hānau kūpono e pale ai i ka hāpai ʻana i kāu wā lapaʻau a no 1 pule ma hope o kāu hopena hope loa. Pono ʻoe e ʻike i kēia lāʻau e hoʻemi ai i ka momona i nā kāne a me nā wahine; Eia naʻe, ʻaʻole pono ʻoe e kuhi ʻaʻole hiki iā ʻoe ke hāpai a i ʻole hiki iā ʻoe ke hāpai i kekahi mea ʻē aʻe. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i ka pralsetinib, e kāhea i kāu kauka. Hoʻopilikia paha ʻo Pralsetinib i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū a i ʻole hoʻolālā e hānai. ʻAʻole pono ʻoe e hānai i ka wā e lawe ana i ka pralsetinib a no 1 mau pule ma hope o kāu hopena hope loa.
• pono ʻoe e ʻike i kēia lāʻau i hoʻemi ai i ka momona i nā kāne a me nā wahine. E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka lawe pralsetinib.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ka pralsetinib. E haʻi paha kāu kauka iā ʻoe mai lawe i ka pralsetinib 5 mau lā ma mua o kou ʻoki ʻana a e haʻi wau iā ʻoe i ka manawa e hoʻomaka ai e lawe hou i ka lāʻau.
• pono ʻoe e ʻike e hoʻonui paha kou kahe koko i kou wā e mālama ai me pralsetinib. E nānā pono kāu kauka i kou kaomi koko, a kauoha paha i ka lāʻau e mālama i ke koko kiʻekiʻe inā ulu ia.
• pono ʻoe e ʻike e ʻike paha ʻoe i ka maʻi tumo lysis syndrome (TLS; kahi kumu i hoʻokumu ʻia e ka wikiwiki o ka haki ʻana o nā hunaola maʻi ʻaʻai e hiki ai ke hōʻeha i nā puʻupaʻa a me nā pilikia ʻē aʻe) i kou wā e lapaʻau ai me pralsetinib I mea e hōʻemi ai i kou makaʻu i ka loaʻa ʻana iā TLS, e noi paha kāu kauka iā ʻoe e inu i ka wai ma mua a i ka wā o kāu mālama ʻana, a i kēlā me kēia manawa e hoʻonui ʻia kāu mahele lāʻau. Eia hou, e hāʻawi aku kāu kauka iā ʻoe i ka lāʻau e lawe ma mua o ka hoʻomaka ʻana a i kāu wā e hoʻomaʻamaʻa ai e pale ai i kēia hopena ʻaoʻao. Inā ʻoe e ʻike i kekahi o nā ʻōuli o TLS, e kāhea koke aku i kāu kauka: fever, chills, nausea, luaʻi, huikau, ka hanu ʻana, ka hopu ʻana i ka puʻuwai puʻuwai ʻole, ka mimi ʻeleʻele a me ke ao, ka luhi ʻole, a i ʻole ka ʻeha a ʻeha pū paha.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala ma ka lā like ke hoʻomanaʻo ʻoe iā ia. A laila, e hoʻomau i kāu papa hana hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Pralsetinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• kōpaʻa
• pāhoehoe
• waha maloo
• ʻehaʻeha a ʻeha iwi paha
• pehu o nā lima, nā kuʻekuʻe wāwae, a me nā wāwae

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i PRECAUTIONS SPECIAL, e kelepona koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• huikau, ʻeha poʻo, pōkole o ka hanu, ʻōpikipiki, a ʻehaʻeha paha
• ke kunu, ka hanu o ka hanu, a me ka kaʻe
• ʻili mae, māluhiluhi, a i ʻole pōkole o ka hanu
• melemele o ka ʻili a mau maka paha, mimi ʻeleʻele ʻeleʻele, kahe ʻana o ke kahe a i ʻole ka palu ma mua o ka maʻamau, ka nele o ka makemake, hoʻemi i ka ikehu, a ʻeha paha ma ka ʻaoʻao ʻākau o ka ʻōpū
• pahu noho ʻeleʻele a lohi hoʻi
• koko ʻulaʻula i nā noho
• luaʻi koko
• mea luaʻi e like me ke kahua kope
• kahe ana ke koko
• kahe koko ʻole ʻana a palapū paha
• hoʻokahe keu
• kahe pinepine ka ihu
• hiamoe, huikau, ʻeha poʻo, a i ʻole paʻakikī e ʻōlelo

Hoʻokumu paha ʻo Pralsetinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kahi hoʻokolohua hoʻokolohua ma mua o kāu mālama ʻana e ʻike inā hiki ke mālama ʻia i kou maʻi ʻaʻai me pralsetinib. E kauoha pū kāu kauka i kekahi mau hoʻokolohua lab ma mua, i ka wā, a ma hope o kāu mālama ʻana e nānā i ka pane o kou kino i ka pralsetinib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Gavreto^®