Mea Kākau: Janice Evans
Lā O Ka Hana: 2 Iulai 2021
HōʻAno Hou I Ka Lā: 14 Nowemapa 2024
Anonim
Antibody-Drug Conjugates in TNBC: Sacituzumab Govitecan
Wikiō: Antibody-Drug Conjugates in TNBC: Sacituzumab Govitecan

Anter

Hiki i ka Sacituzumab govitecan-hziy ke hana i kahi hōʻemi koʻikoʻi o ka helu o nā keokeo keʻokeʻo i kou koko. E kauoha pinepine kāu kauka i nā hoʻokolohua hale hana i kāu mālama ʻana e nānā i ka helu o nā hunaola keʻokeʻo i loko o kou koko. ʻO ka hoʻemi ʻana i ka helu o nā hunaola keʻokeʻo i loko o kou kino e hoʻonui i ka makaʻu e hoʻomohala ʻoe i kahi maʻi koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: fiva, anuanu, ʻāʻī puʻuwai, ka hanu ʻana, ka ʻū a me ka paʻa mau ʻana, ka ʻeha a ʻeha paha i ka wā e mimi ai ʻoe, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi.

Hiki i ka Sacituzumab govitecan-hziy ke kumu i ka palahī nui. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: nā noho humuhumu; pāhoehoe; pahu noho ʻeleʻele a koko paha; nā hōʻailona o ka make wai e like me ka lightheadedness, dizziness, a maule paha; aiʻole inā ʻaʻole hiki iā ʻoe ke inu i nā wai ma ka waha ma muli o ka pualu a me ka luaʻi. E kamaʻilio me kāu kauka e pili ana i ka mea āu e hana ai inā hoʻomohala ʻoe i ka maʻi pākī i kēlā me kēia manawa i kou wā e mālama ai me sacituzumab govitecan-hziy a i ʻole ke kaohi ʻia i loko o 24 mau hola ma hope o ka mālama ʻana me nā lāʻau no ka maʻi diarrhea.


E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua ma mua a i kou wā e mālama ai e nānā i ka pane o kou kino iā sacituzumab govitecan-hziy.

E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka loaʻa ʻana iā sacituzumab govitecan-hziy.

Hoʻohana ʻia ʻo Sacituzumab govitecan-hziy e mālama i kekahi ʻano maʻi ʻaʻai o ka umauma i nā mākua i pāhola ʻia i nā ʻāpana ʻē aʻe o ke kino a ua mālama ʻia me ʻelua mau lāʻau chemotherapy ʻē aʻe. Aia ʻo Sacituzumab govitecan-hziy i loko o ka papa o nā lāʻau i kapa ʻia he conjugates anti-drug. Hana ia ma ka luku ʻana i nā hunaola maʻi ʻaʻai.

Hele mai ʻo Sacituzumab govitecan-hziy ma ke ʻano he pauka e kāwili ʻia me ka wai a ʻimi ʻino ʻia (i loko o kahi aa) ma mua o 1 a 3 mau hola e ke kauka a kahu hānai paha i kahi haukapila a i ʻole kahi wahi olakino. Hāʻawi pinepine ʻia ia i nā lā 1 a me 8 o kahi pōʻaiapuni 21 mau lā. E hana hou ʻia ke kalapona e like me ka ʻōlelo a kāu kauka. Pili ka lōʻihi o kāu lapaʻau i ka maikaʻi o ka pane ʻana o kou kino i ka lāʻau a me nā hopena ʻē aʻe āu e ʻike ai.


Hiki paha i ka inikua Sacituzumab govitecan-hziy ke kanalua, ka luaʻi, a me nā hopena maʻi kūpilikiʻi, i hana pinepine ʻia i ka wā o ka hoʻokomo ʻana o ka lāʻau a i ʻole 24 mau hola o ka loaʻa ʻana o kahi lāʻau. Hāʻawi ʻia ʻoe i nā lāʻau ʻē aʻe e kōkua e pale a mālama i nā hopena. E nānā pono ke kauka a kahu hānai paha iā ʻoe a ma ka liʻiliʻi he 30 mau minuke ma hope o ka hoʻopili ʻana no nā hopena i ka lāʻau. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e haʻi koke aku i kāu kauka: nausea; ka luaʻi; pehu o kou alo, lehelehe, alelo, a puʻu paha; kuni; ʻūpā; pāheʻe; haʻalulu; ʻehu; hives; ʻumeʻume; ʻūhā; a i ʻole paʻakikī i ka hanu ʻana.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau a i ʻole manawa kūmau a paʻa mau paha i kāu lāʻau. Aia kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe a me nā hopena ʻē aʻe āu e ʻike ai. E haʻi pono i kāu kauka i kou ʻano i kou wā e mālama ai me sacituzumab govitecan-hziy.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.


Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana iā sacituzumab govitecan-hziy,

  • e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka sacituzumab govitecan-hziy, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka injection sacituzumab govitecan-hziy. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E hōʻike pono i kekahi o kēia mau mea: carbamazepine (Carbatrol, Equetro, Teril, a me nā mea ʻē aʻe), atazanavir (Reyataz, ma Evotaz), indinavir (Crixivan), irinotecan (Camptosar, Onivyde), phenobarbital, rifampin (Rifadin, i Rifater), and sorafenib (Nexavar). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
  • e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate.
  • E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a inā ʻoe e hoʻolālā i kahi keiki i kahi keiki. ʻAʻole ʻoe a i ʻole kāu pakanā e hāpai i ka wā e loaʻa ana iā ʻoe ka sacituzumab govitecan-hziy injection. Inā he wahine ʻoe i hiki ke hāpai, pono ʻoe e lawe i kahi hōʻike hāpai keiki ma mua o ka hoʻomaka ʻana i ka lāʻau lapaʻau a hoʻohana i ka kaohi hānau hānau maikaʻi i kāu wā e mālama ai a no 6 mau mahina ma hope o kāu hopena hope loa. Inā he kāne ʻoe, pono ʻoe a me kāu pakanā wahine e hoʻohana i ka kaohi hānau ma kāu wā e mālama ai a no 3 mau mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Inā hāpai ʻoe a ʻo kāu hoa paha i ka loaʻa ʻana o ka injection sacituzumab govitecan-hziy, kāhea i kāu kauka. Hiki paha i ka Sacituzumab govitecan-hziy ke hōʻeha i ka fetus.
  • e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā e loaʻa ana iā ʻoe ka sacituzumab govitecan-hziy a no 1 mau mahina ma hope o kāu hopena hope loa.
  • pono ʻoe e ʻike i kēia lāʻau i hoʻemi ʻia ka momona i nā wahine. E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka loaʻa ʻana iā sacituzumab govitecan-hziy.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Inā haʻalele ʻoe i kahi manawa e loaʻa ai iā sacituzumab govitecan-hziy, e kāhea koke aku i kāu kauka.

Hiki i ka Sacituzumab govitecan-hziy ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • kōpaʻa
  • ʻeha nā waha
  • ʻeha ka ʻōpū
  • luhi
  • nalo ʻai ʻole
  • loli ka ʻono
  • poho lauoho
  • ʻili maloʻo
  • ʻeha poʻo
  • ʻeha, puhi ʻana, a i ʻole ka ʻūlū ʻana i nā lima a me nā wāwae paha
  • ʻeha hope a hui pū paha
  • ʻeha ma nā lima a me nā wāwae
  • pehu o nā lima, nā kuʻekuʻe wāwae, a me nā wāwae
  • paʻakikī e hiamoe a hiamoe paha
  • ʻili mae a i ʻole ka luhi a ʻano ʻole paha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i nā ʻARlelo Aʻo IMPORTANT a me HOW, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

  • paopao maʻalahi a hoʻokahe paha; kahe kahe mai ka gum a ka ihu; a i ʻole ke koko i ka mimi a i ʻole ka noho

Hiki i ka Sacituzumab govitecan-hziy ke hana i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Pākuʻi ʻia paha nā ʻōuli o ka overdose:

  • ke kuni, ke anu, ka ʻū, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi

E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana iā sacituzumab govitecan-hziy. Kauoha paha kāu kauka i kekahi mau hoʻokolohua lab ma mua o kou hoʻomaka ʻana i kāu lāʻau e ʻike inā loaʻa paha ʻoe i ka nui o ka hopena no nā hopena ʻaoʻao mai sacituzumab govitecan-hziy e pili ana i kāu hoʻoilina a me kāu make-up.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

  • Trodelvy®
Nānā Hou - 06/15/2020

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