ʻOzanzanod

Anter

• Ma mua o ka lawe ʻana i ka ozanimod,
• Hoʻokumu paha ʻo Ozanimod i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e hōʻoki i ka lawe ʻana i ka ozanimod a kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ʻo Ozanimod e mālama i nā mākua me nā ʻano hou o nā sclerosis he nui (MS; kahi maʻi kahi e holo pono ʻole ai nā ʻalalā a ʻike paha ka poʻe i ka nāwaliwali, numbness, nalo ʻana o ka coordination o nā mākala, a me nā pilikia me ka hihi, kamaʻilio, a me ka mālama ʻana i ka maʻi ʻaʻa) me ke kaʻawale kaʻawale (CIS; nā ʻōuli ʻōuli e hope ma 24 mau hola), nā palapala hoʻihoʻi hou (papa o ka maʻi kahi e piʻi ai nā ʻōuli mai kēlā me kēia manawa), a i ʻole nā ​​ʻano holomua ʻelua (ke ʻano o ka maʻi ma laila pinepine ka hoʻi ʻana). Aia ʻo Ozanimod i kahi papa o nā lāʻau i kapa ʻia ʻo sphingosine l-phosphate receptor modulator. Hana ia ma ka hoʻemi ʻana i ka hana o nā hunaola ʻino e hiki ai ke hōʻino i nā nerve.

Hele mai ʻo Ozanimod ma ke ʻano he capsule e lawe ma ka waha. Lawe mau ʻia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i kēlā me kēia lā. Lawe iā ozanimod ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka ozanimod. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Pau i nā capsule; mai wehe, nau, a wāwahi paha iā lākou.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi haʻahaʻa o ka ozanimod a hoʻonui iki i kāu lāʻau i ka pule mua.

Hiki paha i Ozanimod ke kōkua i ka mālama ʻana i nā ʻōuli sclerosis he nui, akā ʻaʻole ia e hoʻōla iā lākou. E nānā pono kāu kauka iā ʻoe e ʻike i ka maikaʻi o ka hana ozanimod iā ʻoe. He mea nui e haʻi i kāu kauka i kou ʻano i kou wā e mālama ai.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me ka ozanimod a i kēlā me kēia manawa e hoʻopiha hou i kāu kuhikuhi. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka ozanimod,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka ozanimod, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā capsule ozanimod. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka inā lawe ʻoe i kahi mea hoʻopuka MAO e like me isocarboxazid (Marplan), linezolid (Zyvox), methylene blue, phenelzine (Nardil), selegiline (Eldepryl, Emsam, Zelapar), a i ʻole tranylcypromine (Parnate) a i ʻole ua oki ka lawe ʻana i kekahi o kēia mau lāʻau i loko o nā pule ʻelua i hala. E haʻi paha kāu kauka iā ʻoe ʻaʻole pono ʻoe e lawe i ka ozanimod i kēia manawa. Inā hōʻoki ʻoe i ka lawe ʻana i ka ozanimod, pono ʻoe e kali ma ka liʻiliʻi he 14 mau lā ma mua o kou hoʻomaka ʻana e lawe i kahi mea hoʻopuka MAO.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: clopidogrel (Plavix); cyclosporine (Gengraf, Neoral, Sandimmune); eltrombopag (Promacta); erythromycin (E.E.S., Erythromycin, nā mea ʻē aʻe); gemfibrozil (Lopid); nā lāʻau no ke kuʻi puʻuwai kūlike ʻole e like me amiodarone (Nexterone, Pacerone), procainamide, a me quinidine (i Nuedexta); opioid (narcotic) nā lāʻau ʻeha e like me meperidine (Demerol), methadone (Dolophine, Methadose), a me tramadol; rifampin (Rifadin, Rimactane, ma Rifamate, nā mea ʻē aʻe); nā mea kālailai serotonin-reuptake e like me citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, ma Symbyax), fluvoxamine (Luvox), paroxetine (Brisdelle, Prozac, Pexeva), a me sertraline (Zoloft); a me nā serotonin a me nā norepinephrine reuptake inhibitors e like me desvenlafaxine (Khedezla, Pristiq), duloxetine (Cymbalta), milnacipran (Savella), a me venlafaxine (Effexor); a me sotalol (Betapace, Sorine, Sotylize). E haʻi pū aku i kāu kauka inā lawe ʻoe i kekahi o nā lāʻau aʻe, a i ʻole inā lawe ʻoe iā lākou i kēia manawa: alemtuzumab (Campath, Lemtrada); nā corticosteroids e like me dexamethasone, methylprednisolone (Medrol), a me prednisone (Rayos); nā lāʻau no ka maʻi ʻaʻai; a me nā lāʻau e hoʻonāwaliwali a kāohi paha i ka ʻōnaehana pale pale e like me glatiramer (Copaxone, Glatopa) a me interferon beta (Betaseron, Extavia, Plegridy). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me ka ozanimod, no laila e ʻike pono e haʻi aku i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka inā loaʻa ʻoe i kahi puʻuwai puʻuwai, ʻeha o ka umauma, hahau a i ʻole hōʻeha liʻiliʻi, a i ʻole puʻuwai puʻuwai i nā mahina 6 i hala iho nei. Eia kekahi, e haʻi aku i kāu kauka inā loaʻa kahi puʻuwai puʻuwai kūpono ʻole i hoʻoponopono ʻole ʻia e kahi mea hana pacemaker, a i ʻole inā he maʻi hiamoe kou (e hoʻomaha ana i ka hanu no nā manawa pōkole i ka wā hiamoe). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka ozanimod.
• e haʻi i kāu kauka inā he kuni kou, ʻeha ka ʻāʻī, ʻūhā, ʻalalā, nā ʻōpū pehu, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi, inā loaʻa ʻoe i kahi maʻi e hele a hele paha a i hele ʻole paha, a inā ʻaʻole hiki iā ʻoe ke hakakā i nā maʻi. ma muli o kekahi maʻi. Eia kekahi, e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i ke koko kiʻekiʻe, ka wikiwiki o ka puʻuwai, ka maʻi diabetes, uveitis (mumū o ka maka) a i ʻole nā ​​pilikia maka, a i ʻole ka maʻi puʻuwai a i ʻole ate.
• e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Pono ʻoe e hoʻohana i ka kaohi hānau kūpono i kāu mālama ʻana me ka ozanimod a no 3 mau mahina ma hope o kāu hopena hope loa. Inā hāpai ʻoe i ka lawe ʻana i ka ozanimod, e kāhea koke i kāu kauka.
• e haʻi i kāu kauka inā loaʻa kāu lāʻau lapaʻau i nā lā he 30 i hala iho nei ma mua o kou hoʻomaka ʻana i kāu lāʻau me ka ozanimod. ʻAʻohe o nā lāʻau lapaʻau i ka wā o kāu mālama ʻana a i ʻole no 3 mau mahina ma hope o kāu hopena hope loa me ke kamaʻilio ʻole ʻana me kāu kauka.
• e haʻi aku i kāu kauka inā ʻaʻole ʻoe i loaʻa i ka moa moa a ʻaʻole i loaʻa iā ʻoe ka lāʻau lapaʻau o ka moa (varicella). Kauoha paha kāu kauka i kahi hoʻokolohua koko e ʻike inā ua ʻike ʻia ʻoe i ka moa. Pono paha ʻoe e loaʻa i ka lāʻau lapaʻau chickenpox a laila kali i 1 mahina ma mua o ka hoʻomaka ʻana i kāu lāʻau me ka ozanimod.
• pono ʻoe e ʻike he hiki i ka ozanimod ke hoʻoluhi, ka māmā, a me ka maʻule ke ala koke ʻoe mai kahi kūlana wahaheʻe. ʻOi aku ka maʻamau o kēia ke hoʻomaka mua ʻoe e lawe i ka ozanimod. I mea e hōʻalo ai i kēia pilikia, e hele mālie i waho o kahi moe, e hoʻomaha ana i kou mau wāwae i ka papahele no kekahi mau minuke ma mua o ke kū ʻana i luna.

Hiki paha iā ʻoe ke ʻike i kahi hopena koʻikoʻi inā ʻai ʻoe i nā meaʻai i kiʻekiʻe i ka tyramine i kou wā e mālama ai me ka ozanimod. Loaʻa ʻo Tyramine i nā meaʻai a me nā mea inu he nui, e like me ka ʻiʻo, nā moa, nā iʻa, a me nā tīhi i puhi ʻia, ʻelemakule, mālama kūpono ʻole ʻia, a i hōʻino ʻia paha. kekahi mau huaʻai, nā lau, a me nā pī; mea inu ʻona; a me nā huahana hū i hū. E haʻi aku kāu kauka a mea ʻaʻai paha i nā meaʻai āu e pale pono ai, a me nā meaʻai āu e ʻai ai i nā liʻiliʻi. Inā ʻoe e ʻai i kahi meaʻai kiʻekiʻe i ka tyramine ʻoiai e lawe ana i ka ozanimod, e kāhea i kāu kauka.

Inā hala ʻoe i hoʻokahi a ʻoi paha nā lāʻau i loko o nā lā he 14 mua o ka mālama ʻana, e kamaʻilio me kāu kauka ma mua o kou hoʻomaka ʻana e lawe hou. Pono ʻoe e hoʻomaka hou i ka lāʻau i kahi mahele haʻahaʻa a hoʻonui iki i ka lāʻau.

Inā ʻoe e nalo i kahi mahele lāʻau ma hope o nā lā he 14 mua o ka mālama ʻana, e hoʻomau i kāu papa hana maʻamau i ka lā aʻe. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Ozanimod i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻeha kua

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e hōʻoki i ka lawe ʻana i ka ozanimod a kāhea koke aku i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• fiva, uha, ʻāʻī puʻuwai, ihu ihu, a ʻeha a pinepine hoʻi i ka mimiki i ka wā o ka mālama ʻana a i ʻekolu mau mahina ma hope o kāu hopena hope loa
• ʻeha poʻo, ʻāʻī ʻoʻoleʻa, kuni, ʻike i ka mālamalama, nausea, a huikau paha i ka wā o ka mālama ʻana a hiki i 3 mau mahina ma hope o kāu hopena hope loa.
• nausea, luaʻi, nalo o ka makemake ʻole, ʻeha o ka ʻōpū, melemele o ka ʻili a me nā maka, a i ʻole ka mimi ʻeleʻele
• blurriness, aka, a i ʻole kahi makapō i waenakonu o kāu ʻike; ʻike i ka mālamalama; kala ʻokoʻa i kāu hihiʻo a i ʻole nā ​​pilikia ʻike
• ʻehaʻeha kūpikipiki nui, huikau, hoʻololi i ka hihiʻo, a i ʻole ka hopu ʻana
• nāwaliwali ma kekahi ʻaoʻao o ke kino a i ʻole nā ​​clumsiness o nā lima a mau wāwae paha e ʻino i ka holo ʻana o ka manawa. nā hoʻololi i kou noʻonoʻo, hoʻomanaʻo, a kaulike paha; huikau a ʻano pilikino paha; aiʻole ka nalowale o ka ikaika
• ʻehu; hives; a i ʻole ka pehu ʻana o nā lehelehe, ka maka, a me ke alelo
• pōkole hou o ka hanu
• dizziness, māluhiluhi, ʻeha o ka umauma, a i ʻole pāʻūlū a i ʻole hoʻokūʻi ʻole i ka naʻau

Hiki i ka Ozanimod ke hoʻonui i ka makaʻu o ka ulu ʻana i ka maʻi ʻaʻai ʻili. E kamaʻilio me kāu kauka e pili ana i ka makaʻu i ka lawe ʻana i kēia lāʻau.

Hiki ke hoʻonui i kahi ʻāpana o nā hōʻailona MS a me ka hōʻino ʻana o ke kīnā ʻole ma hope o kou oki ʻana i ka lawe ʻana i ka ozanimod. E haʻi i kāu kauka inā hōʻeha kāu mau hōʻailona MS ma hope o kou hōʻoki ʻana i ka ozanimod.

Hoʻokumu paha ʻo Ozanimod i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E loaʻa iā ʻoe kahi electrocardiogram (ECG; hōʻike e hoʻopaʻa i ka hana uila o ka puʻuwai) ma mua o kou lawe ʻana i kāu kau mua. E kauoha pū kāu kauka i kekahi mau hoʻokolohua lab, nā hoʻokolohua maka, a e nānā i kou kahe koko ma mua a i kou wā o ka mālama ʻana e maopopo he palekana ia nou e hoʻomaka i ka lawe ʻana a hoʻomau i ka lawe ʻana i ka ozanimod.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Zeposia^®