ʻO Diroximel Fumarate

Anter

• Ma mua o ka lawe ʻana i diroximel fumarate,
• Hoʻokumu paha ʻo Diroximel fumarate i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ʻo Diroximel fumarate e mālama i nā mākua me nā ʻano like ʻole o ka sclerosis maha (MS; kahi maʻi kahi e holo pono ʻole ai nā ʻalalā a ʻike paha ka poʻe i ka nāwaliwali, numbness, nalo ʻana o ka coordination o nā mākala, a me nā pilikia me ka hihi, kamaʻilio, a me ka mālama ʻana i ka maʻi ʻaʻa) me:

• maʻi hoʻokaʻawale clinically (CIS; nā ʻōuli ʻōuli nerve e kū ma ka liʻiliʻi he 24 mau hola),
• relapsing-remitting forms (papa o ka maʻi kahi e ʻō ai nā ʻōuli mai kēlā me kēia manawa), a i ʻole
• nā papa holomua holomua (papa o ka maʻi kahi e hoʻi pinepine ai ka hoʻi ʻana).

ʻO Diroximel fumarate i kahi papa o nā lāʻau i kapa ʻia ʻo Nrf2 activators. Hana ia ma ka hōʻemi ʻana i ka lī a me ka pale ʻana i nā hōʻino o ke aʻalolo e kumu ai nā ʻōuli o ka sclerosis maha.

Hele mai ʻo Diroximel fumarate ma ke ʻano he lohi-hoʻokuʻu (hoʻokuʻu i ka lāʻau i loko o ka ʻōpū e pale i ka haki ʻana o ka lāʻau e nā ʻōpū o ka ʻōpū) e lawe ka waha. Lawe pinepine ʻia ia i ʻelua mau lā. E lawe ixximel fumarate ma kahi o nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i kaubahximel fumarate e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Lawe ʻia ʻo Diroximel fumarate me ka ʻole o ka meaʻai. Eia nō naʻe, mai lawe ia mea me kahi momona momona, a me nā mea momona momona kiʻekiʻe; pono ka ʻai a i ka meaʻai māmā paha ma mua o 700 mau kalori a ma lalo o 30 mau momona o ka momona.

Mai inu i nā mea inu ʻona i ka manawa like e lawe ai ʻoe i diroximel fumarate.

E hoʻopau i nā capsule hoʻokuʻu lohi i ka holoʻokoʻa; mai hoʻokaʻawale, mauʻu, ʻānai, a pīpī iā lākou.

Hiki iā ʻoe ke lawe i kahi aspirin i uhi ʻole ʻia (325 mg a i ʻole emi) 30 mau minuke ma mua o ka lawe ʻana i kaubahximel fumarate e hoʻemi i ka manawa o ka pīpī (ʻulaʻula maka) i kāu wā e lapaʻau ai.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi lāʻau haʻahaʻa o diroximel fumarate a hoʻonui i kāu lāʻau ma hope o 7 mau lā.

Hiki iā Diroximel fumarate ke kōkua i ka mālama ʻana i nā sclerosis he nui, akā ʻaʻole ia e hoʻōla iā ia. E hoʻomau i ka lawe ʻana i diroximel fumarate ʻoiai inā maikaʻi ʻoe. Mai hooki i ka lawe ʻana i ka diroximel fumarate me ka walaʻau ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i diroximel fumarate,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i diroximel fumarate, dimethyl fumarate (Tecfidera), nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o kaxximel fumarate hoʻopaneʻe i ka hoʻokuʻu capsules. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• E haʻi i kāu kauka inā lawe ʻoe i ka dimethyl fumarate (Tecfidera). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i diroximel fumarate inā ʻoe e lawe i kēia lāʻau.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa ʻoe i kahi maʻi, me nā maʻi e hele mai ana a hele a me nā maʻi maʻi mau ʻole e hele, a i ʻole he helu keokeo haʻahaʻa keokeo a i ʻole ka maʻi ate a me nā puʻupaʻa.
• e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i diroximel fumarate, e kāhea i kāu kauka.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Diroximel fumarate i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• mehana, ʻulaʻula, ʻili, a ʻaʻā paha o ka ʻili
• ʻeha ka ʻōpū
• pāhoehoe
• nausea
• ka luaʻi
• puʻuwai puʻuwai

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• pilikia i ka hanu ʻana a i ʻole ke ale ʻana
• hives
• hūwī
• ka pehu o ka maka, ka ʻāʻī, ke alelo, nā lehelehe, nā maka, nā lima, nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
• nāwaliwali ma kekahi ʻaoʻao o ke kino, palaualelo i kou mau lima a mau wāwae paha, nā pilikia ʻike, nā loli i ka noʻonoʻo a me ka hoʻomanaʻo, huikau, a i ʻole nā ​​ʻano pilikino.
• luhi, nalo o ka makemake ʻole, ʻeha ma ka ʻaoʻao ʻākau o kou ʻōpū, mimi ʻeleʻele, a melemele o ka ʻili a me nā maka

Hoʻokumu paha ʻo Diroximel fumarate i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i kāu kauka ke kauoha i kahi hoʻokolohua koko ma mua o kou hoʻomaka ʻana i kāu lāʻau lapaʻau a kauoha paha i kekahi mau hoʻokolohua hoʻokolohua i kou wā e mālama ai e nānā i ka pane o kou kino iā diroximel fumarate.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Helu lehulehu^®