Mea Kākau: Marcus Baldwin
Lā O Ka Hana: 17 Iune 2021
HōʻAno Hou I Ka Lā: 17 Nowemapa 2024
Anonim
Tubercolosi, parere europeo positivo all’approvazione di pretomanid per le forme multiresistenti (cr
Wikiō: Tubercolosi, parere europeo positivo all’approvazione di pretomanid per le forme multiresistenti (cr

Anter

Hoʻohana ʻia ʻo Pretomanid me ka bedaquiline (Sirturo) a me ka linezolid (Zyvox) e mālama ai i ka tuberculosis kūpona (MDR-TB) Aia ʻo Pretomanid i ka papa o nā lāʻau i kapa ʻia antimycobacterial. Hana ia ma ka luku ʻana i nā koʻohune ke kumu i ka maʻi kō.

Hele mai ʻo Pretomanid ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i kēlā me kēia lā me ka meaʻai no 26 mau pule a ʻoi paha. Lawe i ka pretomanid ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i ka pretomanid e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E hoʻopau i nā papa i ka wai.

E hoʻomau i ka lawe ʻana i ka pretomanid a hiki i kou hoʻopau ʻana i ke kuhikuhi a mai haʻalele i nā lāʻau, ʻoiai inā ʻoe e ʻoi aku ka maikaʻi. Inā kū ʻoe i ka lawe ʻana i ka pretomanid ma mua koke a lele paha i nā lāʻau, ʻaʻole hiki ke mālama pono ʻia i kāu maʻi a hiki i ke kūpikipiki ke kūʻē i nā antibiotic. E paʻakikī kēia i kāu maʻi e mālama i ka wā e hiki mai ana. E komo pū ʻoe i kahi papahana hoʻōla pono e nānā pono iā ʻoe e lawe i kāu lāʻau āpau e like me ke kuhikuhi. I kēia papahana, hāʻawi kahi limahana olakino iā ʻoe i kēlā me kēia lāʻau o ka lāʻau lapaʻau a e nānā ʻo ia iā ʻoe e ale i ka lāʻau.


Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka pretomanid,

  • e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka pretomanid, bedaquiline, linezolid, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa pretomanid. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: efavirenz (Sustiva, ma Atripla), methotrexate (Rheumatrex, Trexall), a i ʻole rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me ka pretomanid, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
  • e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St. Mai lawe iā St. John's wort a i ʻole nā ​​huahana lāʻau ʻē aʻe i ka lawe ʻana i ka pretomanid.
  • e haʻi i kāu kauka inā lōʻihi a lōʻihi paha ka QT maʻi o ʻoe a o kekahi ʻohana paha (ke ʻano e hoʻonui ai i ka makaʻu o ke kūkulu ʻana i kahi puʻuwai puʻuwai ʻole e hiki ai i ka maʻule a i ʻole ka make koke ʻana) a i ʻole kekahi ʻano o ka puʻuwai puʻuwai ʻole a i ʻole ka pilikia o ka puʻuwai puʻuwai. Eia kekahi, e haʻi i kāu kauka inā loaʻa a i ʻole loaʻa iā ʻoe nā haʻahaʻa o ke koko o ka calcium, magnesium a i ʻole potassium i loko o kou koko, kahi puʻuwai puʻuwai, puʻuwai puʻuwai (HF; kahi i hiki ʻole ai i ka puʻuwai ke pauma i ke koko i nā ʻāpana ʻē aʻe o ke kino) , ka hopu ʻana, ka maʻi HIV, a i ʻole ka thyroid, ka ate a me nā maʻi pākī.
  • e haʻi i kāu kauka inā hāpai ʻoe, hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana i ka pretomanid, e kāhea i kāu kauka.
  • pono ʻoe e ʻike e hōʻalo i ka inu ʻana i nā mea inu ʻona. ʻO ka inu ʻana i ka waiʻona e hoʻonui ai i ka makaʻu e ʻike ʻoe i nā hopena koʻikoʻi mai ka pretomanid.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.


E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Pretomanid ke kumu i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • huehue
  • ʻeha poʻo
  • puʻuwai puʻuwai
  • nalo ʻai ʻole
  • Kaumaha emi
  • hūwī
  • ʻūlili
  • ʻeha ka ʻōpū
  • nausea
  • ka luaʻi
  • pāhoehoe
  • kōpaʻa
  • ʻili maloʻo
  • paʻakikī e hiamoe a hiamoe paha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

  • nalo o ka makemake ʻole, kahoʻi, maka melemele a i ʻole ka ʻili, ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū, a me ka mimi ʻeleʻele
  • ʻeha, numbness, a nāwaliwali paha i nā lima, nā wāwae, a i ʻole nā ​​ʻāpana ʻē aʻe o ke kino; a i ʻole nā ​​pilikia me ke kaulike
  • loli ka hihiʻo
  • wikiwiki a i ʻole kōkō puʻuwai puʻuwai; luuluu; a maule paha
  • ʻili mae a luhi nui paha
  • nausea hou a me ka luaʻi; hanu wikiwiki; huikau; a luhi paha
  • ʻāwīwī, ʻehaʻeha i ka umauma, ʻoiai ke hanu i loko a i waho

Hiki i ka Pretomanid ke kumu i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.


Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua hoʻokolohua ma mua a i kou wā e mālama ai e nānā i ka pane o kou kino i ka pretomanid. Pono ʻoe e loaʻa i kahi electrocardiogram (ECG; kahi hoʻāʻo e ana i ka hana uila o ka puʻuwai) ma mua o kāu lapaʻau a me nā manawa he nui i kou wā e mālama ai e ʻike pehea ka hopena o kēia lāʻau i ka puʻuwai o kou puʻuwai.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

Nānā Hou - 11/15/2019

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