Selinexor

Anter

• Ma mua o ka lawe ʻana i selinexor,
• Hoʻokumu ʻo Selinexor i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ʻo Selinexor me dexamethasone e mālama i nā myeloma he nui (kahi ʻano maʻi ʻaʻai o ka iwi iwi) i hoʻi mai a i ʻole i pane i nā mea ʻehā ʻē aʻe. Hoʻohana ʻia ʻo Selinexor me ka bortezomib a me dexamethasone e mālama i nā myeloma he nui i nā mea maʻi i mālama mua ʻia me hoʻokahi lāʻau ʻē aʻe. Hoʻohana ʻia ia e mālama i kekahi ʻano diffuse nui B-cell lymphoma (DLBCL; kahi ʻano o ka maʻi ʻaʻai e hoʻomaka i loko o nā keʻokeʻo koko keʻokeʻo) i nā mākua i hoʻi a maʻi ʻole paha kā lākou maʻi ʻaʻai i ʻelua mau lapaʻau ʻē aʻe. Aia ʻo Selinexor i loko o ka papa o nā lāʻau i kapa ʻia he mea kāohi i nā mea hoʻopukapuka nukelea (SINE). Hana ia ma ka luku ʻana i nā hunaola maʻi ʻaʻai.

Hele mai ʻo Selinexor ma ke ʻano he papa e lawe ma ka waha me ka ʻole o ka meaʻai. No ka hoʻohana pū ʻana me dexamethasone no ka mālama ʻana i ka myeloma maha a i ʻole no ka mālama ʻana o DLBCL, lawe mau ʻia ka selinexor i nā lā 1 a me 3 o kēlā me kēia pule. No ka hoʻohana pū ʻana me bortezomib a me dexamethasone no ka mālama ʻana i ka myeloma maha, lawe pinepine ʻia ʻo selinexor i hoʻokahi manawa i ka pule. Lawe i ka selinexor ma kahi o ka manawa like o ka lā i kēlā me kēia lā āu e lawe ai. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pono i selinexor e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa i ka wai; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Inā ʻoe e luaʻi ma hope o ka lawe ʻana i selinexor, mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

E haʻi paha kāu kauka iā ʻoe e lawe i ka lāʻau e pale ai i ka pualu a me ka luaʻi ma mua a i kou wā e mālama ai me selinexor.

Pono paha kāu kauka e hōʻoki a hoʻopau paha i kāu lāʻau a hōʻemi paha i kāu lāʻau inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. E pono e haʻi i kāu kauka i kou ʻano i kou wā e mālama ai me selinexor.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i selinexor,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka selinexor, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hoʻohui i nā papa selinexor. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• E haʻi aku i kāu kauka inā loaʻa a maʻi paha ʻoe i kēia manawa, inā ua loaʻa a loaʻa paha iā ʻoe kahi pilikia kahe o ke kahe, a inā he cataract kou (ke ao o ka maka o ka maka).
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe i kahi hōʻoia hāpai maikaʻi ʻole ma mua o kou hoʻomaka ʻana i ka selinexor. Inā he wahine ʻoe, ʻaʻole pono ʻoe e hāpai i ka wā e lawe ana ʻoe i ka selinexor a no 1 mau pule ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Inā he kāne ʻoe, pono ʻoe a me kāu pakanā wahine e hoʻohana i ka kaohi hānau i ka wā o kāu mālama ʻana a hoʻomau i ka hoʻohana ʻana i ka kaohi hānau no 1 pule ma hope o kāu hopena hope loa. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i selinexor, e kāhea koke aku i kāu kauka. Hoʻopilikia paha ʻo Selinexor i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā e lawe nei ʻoe i selinexor a no 1 pule ma hope o kāu hopena hope loa.
• pono ʻoe e ʻike i kēia lāʻau i hoʻemi ai i ka momona i nā kāne a me nā wahine.
• pono ʻoe e ʻike i ka selinexor e hoʻomoe ai i ka hiamoe a i ʻole hoʻonāukiuki ai. Mai hoʻokele i kahi kaʻa a hana i nā mīkini a ʻike ʻoe i ka hopena o kēia lāʻau iā ʻoe.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E paipai paha kāu kauka e inu ʻoe i nā wai a lawa a ʻai i ka nui o nā calorie i kāu mālama ʻana.

Inā ʻoe e nalo i kahi mahele lāʻau, e lele i kēlā lāʻau a lawe i kāu lāʻau i kāu lā a me ka manawa i hoʻonohonoho pinepine ʻia. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu ʻo Selinexor i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• ka luaʻi
• pāhoehoe
• kōpaʻa
• Kaumaha emi
• nalo ʻai ʻole
• luhi loa
• paʻakikī e hiamoe a hiamoe paha
• ʻeha poʻo
• loli ka ʻono

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• maʻalahi ke kahe ʻana a i ʻole ka palapū
• luhi, ʻili mae a i ʻole ka pokole o ka hanu
• fiva, uā, haʻalulu, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• ke ʻike nei i nā mea a i ʻole ka lohe ʻana i nā leo i ʻole
• huikau
• ʻike hihi ʻole a pālua paha
• hoʻonui i ka ʻike i ka mālamalama a me ka lilelile

Hoʻokumu paha ʻo Selinexor i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E nānā kāu kauka i kou kaumaha o ke kino a kauoha i kekahi mau hoʻokolohua lab ma mua a i kou wā e mālama ai e nānā i ka pane o kou kino i ka selinexor.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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