Esketamine Nasal Spray

Anter

• Ma mua o ka hoʻohana ʻana i ka spray nasal esketamine,
• Hiki i ka ʻeha nasket Esketamine ke hopena i nā hopena. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

ʻO ka hoʻohana ʻana i ka ʻehu nasket esketamine ka mea e hoʻohiamoe ai, maule ai, paupauaho ai, hopohopo, a wili ai, a i ʻole ka manaʻo e hemo ai mai kou kino, nā manaʻo, nā manaʻo, kahi a me ka manawa. E hoʻohana ʻoe i ka spray nasal esketamine iā ʻoe iho i kahi wahi olakino, akā e nānā mua kāu kauka iā ʻoe ma mua, i ka wā, a ma kahi o 2 mau hola ma hope o kāu lapaʻau. Pono ʻoe e hoʻolālā no kahi mea mālama a lālā ʻohana paha e hoʻokele iā ʻoe i ka home ma hope o ka hoʻohana ʻana i ka esketamine. Ma hope o kou hoʻohana ʻana i ka spray nasal esketamine, mai hoʻokele i kahi kaʻa, hana i nā mīkini, a i ʻole hana i kekahi mea e pono ai ʻoe e makaʻala a hiki i ka lā aʻe ma hope o ka hiamoe hiamoe o ka pō. E haʻi koke aku i kāu kauka inā loaʻa ʻoe i ka luhi nui, maʻule, ʻeha o ka umauma, ka hanu ʻana o ka manawa, ʻeha ke poʻo ʻeha, hoʻololi i ka ʻike, haʻalulu ʻole i kahi ʻāpana o ke kino, a i ʻole ka hopu ʻana.

Hoʻokumu paha ka Esketamine. E haʻi i kāu kauka inā inu ʻoe a i ʻole kekahi i kou ʻohana a inu paha i ka nui o ka waiʻona, hoʻohana a hoʻohana paha i nā lāʻau lapaʻau o ke alanui, a i ʻole hoʻohana nui ʻole i nā lāʻau lapaʻau.

ʻO kahi liʻiliʻi o nā keiki, ʻōpio, a me nā ʻōpio ʻōpio (a hiki i ka 24 mau makahiki) i lawe i nā antidepressants ('ʻelele kūlana') i ka manawa o nā noiʻi maʻi ʻana i lilo i suicidal (e noʻonoʻo e pili ana i ka hōʻeha a pepehi paha iā ʻoe iho a i ʻole ke hoʻolālā ʻana a hoʻāʻo ʻana paha e hana pēlā). ʻO nā keiki, ʻōpio, a me nā ʻōpio ʻōpio e lawe i nā antidepressants e mālama i ke kaumaha a i ʻole nā ​​maʻi noʻonoʻo ʻē aʻe e lilo i suicidal ma mua o nā keiki, ʻōpio, a me nā ʻōpio makua ʻole i lawe ʻole i nā antidepressants e mālama i kēia mau ʻano. Eia naʻe, ʻaʻole maopopo ka poʻe loea e pili ana i ka nui o kēia pilikia a pehea e noʻonoʻo ai i ka hoʻoholo ʻana inā paha e lawe kahi keiki a mea ʻōpio paha i kahi antidepressant. Pono nā keiki ʻaʻole hoʻohana i ka esketamine.

Pono ʻoe e ʻike e loli paha kou olakino noʻonoʻo i nā ala i manaʻo ʻole ʻia ke hoʻohana ʻoe i ka esketamine a i ʻole nā ​​antidepressants ʻē aʻe inā he makua ʻoe ma luna o nā makahiki he 24. ʻO ʻoe, kou ʻohana, a i ʻole kāu mea mālama e kāhea koke aku i kāu kauka inā ʻike ʻoe i kekahi o kēia mau ʻōuli: ke kaumaha hou a i ʻole ke kaumaha paha; ke noʻonoʻo nei e pili ana i ka hōʻino a pepehi paha iā ʻoe iho, a i ʻole ke hoʻolālā ʻana a hoʻāʻo ʻana paha e hana pēlā; hopohopo nui loa; hoʻonāukiuki; hoʻouka weliweli; paʻakikī e hiamoe a hiamoe paha; hana kolohe; ukiuki; hana me ka noʻonoʻo ʻole; hoʻomaha ʻole loa; a me ka pīhoihoi pīhoihoi frenzied. E ʻike pono i kou ʻohana a mea mālama paha e ʻike i nā hōʻailona e koʻikoʻi paha i hiki iā lākou ke kāhea i ke kauka inā ʻaʻole hiki iā ʻoe ke ʻimi iā ʻoe lāʻau ponoʻī.

Ma muli o nā pilikia o kēia lāʻau, loaʻa wale ka esketamine ma o kahi papahana hoʻokaʻawale palena papaha. ʻO kahi papahana i kapa ʻia ʻo Spravato Risk Evaluation and Mitigation Strategies (REMS) polokalamu. Pono ʻoe, kāu kauka, a me kāu kauka e kākau inoa i ka papahana Spravato REMS ma mua o ka loaʻa ʻana o kēia lāʻau iā ʻoe. E hoʻohana ʻoe i ka esketamine nasal spray i kahi hale olakino ma lalo o ka nānā ʻana a ke kauka a i ʻole ʻoihana ola.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E nānā kāu kauka i kou kaomi koko ma mua a ma ka liʻiliʻi he 2 mau hola ma hope o kou hoʻohana ʻana i ka esketamine i kēlā me kēia manawa.

E hāʻawi aku kāu kauka a mea kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka mālama ʻana me ka esketamine a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Hoʻohana ʻia ka ʻehu nasket Esketamine me kahi antidepressant ʻē aʻe, i lawe ʻia e ka waha, e mālama i ke kaumaha kū ʻole i ka lāʻau lapaʻau (TRD; kaumaha e hoʻomaikaʻi ʻole me ka mālama ʻana) i nā mākua. Hoʻohana ʻia ia me kahi antidepressant ʻē aʻe, i lawe ʻia e ka waha, e mālama i nā hōʻailona depressive i nā mākua me nā maʻi depressive nui (MDD) a me nā manaʻo suicidal a hana paha. Aia ʻo Esketamine i kahi papa o nā lāʻau i kapa ʻia ʻo NMDA receptor antagonists. Hana ia ma ka hoʻololi ʻana i ka hana o kekahi mau mea kūlohelohe i ka lolo.

Hele mai ka Esketamine ma ke ʻano he wai (wai) e pīpī i ka ihu. No ka mālama ʻana i ke kaumaha kūpaʻa kūpaʻa, ʻāpī pinepine ʻia i ka ihu i ʻelua mau manawa o ka pule i nā pule he 1-4, hoʻokahi pule i kēlā me kēia pule 5-8, a laila hoʻokahi manawa i ka pule a i hoʻokahi manawa i kēlā me kēia 2 mau pule i ka pule 9 a ma ʻō. No ka mālama ʻana i nā ʻōuli depressive i nā mākua me ka maʻi depressive nui a me nā manaʻo suicidal a i ʻole nā ​​hana, ua pīpī pinepine ʻia i ka ihu i ʻelua mau manawa o ka pule a hiki i 4 mau pule. Pono e hoʻohana ʻia ka Esketamine i kahi wahi olakino.

Mai ʻai no 2 mau hola a inu paha i nā wai no ka liʻiliʻi he 30 mau minuke ma mua o ka hoʻohana ʻana i ka esketamine nasal spray.

Hāʻawi kēlā me kēia nasal spray spray i 2 sprays (hoʻokahi spray no kēlā me kēia nostril). ʻElua mau kiko ʻōmaʻomaʻo ma ka hāmeʻa e haʻi iā ʻoe ua piha ka ʻehu nasal, hoʻokahi kiko ʻōmaʻomaʻo e haʻi iā ʻoe ua hoʻohana ʻia hoʻokahi spray, a ʻaʻohe kiko ʻōmaʻomaʻo e hōʻike i ka hoʻohana ʻia ʻana o ka mahele lāʻau piha.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka hoʻohana ʻana i ka spray nasal esketamine,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka esketamine, ketamine, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka esketamine nasal spray. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono e haʻi i kekahi o kēia mau mea: amphetamines, nā lāʻau no ka hopohopo, armodafinil (Nuvigil), MAO mea kāohi e like me phenelzine (Nardil), procarbazine (Matulane), tranylcypromine (Parnate), a me selegiline (Eldepryl, Emsam, Zelapar); nā lāʻau lapaʻau ʻē aʻe no ka maʻi noʻonoʻo, methylphenidate (Aptension, Jornay, Metadate, a me nā mea ʻē aʻe), modafanil, nā lāʻau opioid (narcotic) no ka ʻeha, nā lāʻau no ka hopu ʻana, nā mea hoʻohiamoe, nā lāʻau moe, a me nā tranquilizers. E haʻi i kāu kauka inā ua lawe koke ʻoe i kekahi o kēia mau lāʻau.
• inā ʻoe e hoʻohana nei i ka corticosteroid ihu e like me ciclesonide (Alvesco, Omnaris, Zetonna) a me mometasone (Asmanex) a i ʻole decongestant nasal e like me oxymetazoline (Afrin) a me phenylephrine (Neosynephrine), hoʻohana ia ma ka liʻiliʻi he 1 hola ma mua o ka hoʻohana ʻana i ka esketamine nasal spray.
• e haʻi i kāu kauka inā he maʻi kīʻaha koko kou i ka lolo, ka umauma, ka ʻōpū, nā lima a me nā wāwae paha. loaʻa kahi malformation arteriovenous (kahi pilina maʻamau ma waena o kāu mau uaua a me nā ʻāpana); a i ʻole he moʻolelo kahe o ke kahe ʻana i kou lolo. E haʻi paha kāu kauka iā ʻoe mai hoʻohana i ka spray nasal esketamine.
• e haʻi i kāu kauka inā ua loaʻa ʻoe i ka maʻi hahau, ka puʻuwai puʻuwai, ka ʻeha o ka lolo, a i ʻole kekahi ʻano kumu e hoʻonui ai i ka lolo. E haʻi i kāu kauka inā ʻike ʻoe, lohe, a lohe paha i nā mea ʻaʻole ma laila; a i ʻole manaʻoʻiʻo i nā mea ʻoiaʻiʻo ʻole. Eia kekahi, e haʻi i kāu kauka inā loaʻa a i ʻole loaʻa paha iā ʻoe ka maʻi puʻuwai puʻuwai, maikaʻi ʻole o ka puʻuwai, hypertension (ke koko kiʻekiʻe), kahi puʻuwai lohi a i ʻole kaulike ʻole, ka hanu ʻana, ka ʻeha o ka umauma, a me ka maʻi ate a puʻuwai paha.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Inā hāpai ʻoe i ka hoʻohana ʻana i ka spray nasal esketamine, e kāhea koke i kāu kauka. Hoʻopilikia ka ʻehu esketamine i ka fetus.
• e haʻi i kāu kauka inā ʻoe e hānai umauma ana. ʻAʻole pono ʻoe e hānai i ka wā e hoʻohana ana i ka esketamine nasal spray.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e hoʻohana nei ʻoe i ka esketamine nasal spray.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Inā ʻoe e nalo i kahi kau lapaʻau e hoʻokaʻaʻike koke aku i kāu kauka e hoʻonohonoho i kahi manawa. Inā ʻike ʻoe i kahi lāʻau lapaʻau a lilo i ke kaumaha o kou kaumaha, pono paha i kāu kauka e hoʻololi i kāu lāʻau a i ʻole ka papa kuhikuhi.

Hiki i ka ʻeha nasket Esketamine ke hopena i nā hopena. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• pinepine, wikiwiki, wela, a i ʻole ka mimino ʻeha
• kōpaʻa
• pāhoehoe
• waha maloo
• nausea
• ka luaʻi
• pilikia i ka noʻonoʻo a ʻona paha
• ʻeha poʻo
• ʻono ʻokoʻa a metallic paha i ka waha
• makaʻu ʻole o ka ihu
• ukiuki o ka puʻu
• hoʻonui sweating

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o nā ʻōuli i helu ʻia i ka ʻlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hiki i ka ʻeha esketamine ihal ke kumu i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka hoʻohana ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Spravato^®