Mea Kākau: Gregory Harris
Lā O Ka Hana: 16 Apelila 2021
HōʻAno Hou I Ka Lā: 19 Nowemapa 2024
Anonim
Molecular Tumor Board fev/2022: mutação em genes relacionados ao reparo por recombinação homóloga
Wikiō: Molecular Tumor Board fev/2022: mutação em genes relacionados ao reparo por recombinação homóloga

Anter

Hoʻohana ʻia ʻo Talazoparib e mālama i kekahi ʻano o ka maʻi ʻaʻai o ka umauma i pāhola i loko o ka umauma a i nā wahi ʻē aʻe o ke kino. Aia ʻo Talazoparib i loko o ka papa o nā lāʻau i kapa ʻia he mau mea hoʻopale poly (ADP-ribose) polymerase (PARP). Hana ia ma ke kāohi ʻana a i ʻole ka hoʻolohi ʻana i ka ulu ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Talazoparib ma ke ʻano he capsule e lawe ma ka waha. Lawe pinepine ʻia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i ka lā. Lawe iā talazoparib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe pololei i ka talazoparib. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā capsule holoʻokoʻa; mai hoʻonā a wehe iā lākou.

Inā luaʻi ʻoe ma hope o ka lawe ʻana i ka talazoparib, mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau o talazoparib, a i ʻole paʻa mau a hoʻomaha paha i kāu lāʻau lapaʻau, inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. E haʻi pono i kāu kauka i kou ʻano i kou wā e mālama ai me talazoparib.


E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i talazoparib,

  • e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka talazoparib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā capsules talazoparib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono e haʻi i kekahi o kēia mau mea: amiodarone (Cordarone, Pacerone), carvedilol (Coreg), clarithromycin (Biaxin, ma Prevpac), itraconazole (Onmel, Sporanox), sulfasalazine (Azulfidine), a me verapamil (Calan, Covera, Isoptin, ʻO Tarka, Verelan). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me talazoparib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
  • e haʻi i kāu kauka inā loaʻa ʻoe a i ʻole loaʻa i ka maʻi maʻi kidney.
  • E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a inā ʻoe e hoʻolālā i kahi keiki i kahi keiki. ʻAʻole hāpai ʻoe a me kāu pakanā ʻoiai ʻoe e lawe nei iā talazoparib. Inā he wahine ʻoe, hiki i kāu kauka ke hana i kahi hoʻokolohua hāpai ma mua o kou hoʻomaka ʻana i ka lāʻau, a pono ʻoe e hoʻohana i ka kaohi hānau e pale i ka hāpai ʻana i kāu mālama talazoparib a no 7 mau mahina ma hope o kāu hopena hope loa. Inā he kāne ʻoe, pono ʻoe a me kāu pakanā e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i ka wā o kāu mālama ʻana me talazoparib a no 4 mau mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i kāu wā o kāu mālama ʻana. Hiki i Talazoparib ke hoʻemi i ka momona i nā kāne. Eia nō naʻe, ʻaʻole pono ʻoe e kuhi ʻaʻole hiki iā ʻoe a i ʻole kāu pakanā ke hāpai. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i talazoparib, e kāhea i kāu kauka. Hiki iā Talazoparib ke hōʻeha i ka fetus.
  • e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā e lawe ana ʻoe i ka talazoparib a no 1 mau mahina ma hope o kāu hopena hope loa.
  • inā ke ʻoki nei ʻoe, e like me ke ʻoki niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe nei ʻoe i ka talazoparib.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.


Inā ʻoe e nalo i kahi lāʻau, haʻalele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Talazoparib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • nausea
  • nalo ʻai ʻole
  • pāhoehoe
  • ka luaʻi
  • ʻeha ka ʻōpū
  • loli i ke ʻano o ka ʻono
  • puʻuwai puʻuwai
  • poho lauoho

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

  • nāwaliwali
  • luhi nei
  • Kaumaha emi
  • ke kuni, ke anu, ka ʻū, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
  • pokole o ka hanu
  • puʻuwai wikiwiki
  • ʻeha poʻo, ʻūpū, huikau, a i ʻole ʻili pale
  • ke koko i ka mimi a i ʻole ka noho
  • kahe koko ʻole ʻana a palapū paha

Hoʻokumu paha ʻo Talazoparib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).


E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i talazoparib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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