ʻO Duvelisib

Anter

• Ma mua o ka lawe ʻana i duvelisib,
• Hoʻokumu paha ʻo Duvelisib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻokumu paha ʻo Duvelisib i nā maʻi nui a weliweli paha i ke ola. E haʻi aku i kāu kauka inā loaʻa ʻoe i ka maʻi, a i ʻole inā i loaʻa iā ʻoe he cytomegalovirus (CMV; kahi maʻi viral e hōʻeha paha i nā ʻōuli i nā maʻi me nā ʻōnaehana pale nawaliwali). Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: ke kuni, ka ʻeha o ka ʻāʻī, ke anuanu, ka hanu ʻole, a me nā ʻōuli ʻino ʻē aʻe.

Hoʻokumu paha ʻo Duvelisib i ka maʻi diarrhea a i ʻole colitis (ʻōhū o ka ʻōpū nui). E haʻi i kāu kauka inā loaʻa ʻoe i ka maʻi pākī a i ʻole he colitis a i ʻole nā ​​ʻano ʻē aʻe e hoʻopili i kou ʻōpū a i ʻole kou ʻōpū. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: ka hoʻonui ʻana i ka nui o ka ʻōpū i ka lā, ke koko i kāu pahu, a i ʻole nā ​​ʻeha o ka ʻōpū a ʻeha paha.

Hoʻokumu paha ʻo Duvelisib i nā hopena ʻili koʻikoʻi a hoʻoweliweli paha i ke ola. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: he ʻehu hou a ʻoi aku paha ka ʻino, pākī me ke kuni, ʻūpiki me ka ʻili, palapū a ʻili ʻili paha, a i ʻole nā ​​ʻeha ʻeha a ʻeha paha ma kou ʻili, lehelehe, a i loko paha o kou waha.

Hoʻokumu paha ʻo Duvelisib i ka maʻi maʻi maʻi weliweli a i ʻole hoʻoweliweli ola (ka pehu ʻana o nā akemāmā). E haʻi i kāu kauka inā loaʻa ʻoe i ka maʻi maʻi a i ʻole nā ​​pilikia hanu. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: hou a hōʻeha paha i ka ʻū, paʻakikī i ka hanu ʻana, i ke kani ʻana, a i ʻole ka liʻiliʻi o ka hanu.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua e nānā i ka pane o kou kino iā duvelisib.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka pepa ʻikepili a ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me duvelisib a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Hoʻohana ʻia ʻo Duvelisib e mālama i ka leukemia lymphocytic mau (CLL; kahi ʻano o ka maʻi ʻaʻai e hoʻomaka i nā kahe koko keʻokeʻo) a i ʻole lymphocytic lymphoma liʻiliʻi (SLL; kahi ʻano o ke kanesa e hoʻomaka ka hapanui i nā lymph node) i hoʻi a pane ʻole paha i ʻelua mau lapaʻau ʻē aʻe. Hoʻohana ʻia ia e mālama i kekahi ʻano o ka lymphoma follicular (FL; kahi ʻano o ke kanesa e hoʻomaka i nā hunaola keokeo) i nā mākua i hoʻi a hōʻole ʻole paha i nā maʻi ʻē aʻe ʻelua. Aia ʻo Duvelisib i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i nā hōʻailona e hoʻonui ai i nā hunaola maʻi ʻino. Kōkua kēia i mea e hōʻoki ai i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Duvelisib ma ke ʻano he capsule e lawe ma ka waha. Lawe pinepine ʻia ia i ʻelua mau lā me ka ʻai ʻole. Lawe i ka duvelisib ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i ka duvelisib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i ka capsule holoʻokoʻa; mai wehe, nau, a wāwahi paha iā lākou.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau o duvelisib a i ʻole e haʻi iā ʻoe e hōʻoki i ka lawe ʻana i ka lāʻau no kekahi manawa a mau loa paha inā ʻike ʻoe i nā hopena ʻē aʻe i kāu lapaʻau ʻana. Aia kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe a me nā hopena ʻē aʻe āu e ʻike ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana. E hoʻomau i ka lawe ʻana i ka duvelisib ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ka duvelisib me ke kamaʻilio ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i duvelisib,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka duvelisib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā capsule duvelisib. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, lawe ʻoe a hoʻolālā paha e lawe. E ʻōlelo pono i kekahi o kēia mau mea: carbamazepine (Epitol, Tegretol, Teril, a me nā mea ʻē aʻe); clarithromycin (Biaxin); nā lāʻau i hoʻohana ʻia e mālama ai i ka maʻi pale maʻi (HIV) e like me efavirenz (Sustiva, i Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), a me ritonavir (Norvir, i nā mea ʻē aʻe); itraconazole (Onmel, Sporanox); ketoconazole, midazolam; nefazodone; phenobarbital; phenytoin (Dilantin, Phenytek); pioglitazone (Actos); rifabutin (Mycobutin); a me rifampin (Rifadin, Rimactane, ma Rifamate). Pili pū paha nā lāʻau ʻē aʻe he nui me duvelisib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Pono ʻoe e hōʻike i kahi hāpai hāpai ma mua o kou hoʻomaka ʻana e lawe i ka duvelisib. ʻAʻole ʻoe e hāpai i ka wā o kāu mālama ʻana me duvelisib. Inā he wahine ʻoe, pono ʻoe e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i ka wā o kāu mālama ʻana me duvelisib a ma ka liʻiliʻi ʻo 1 mahina ma hope o kāu hopena hope loa. Inā he kāne ʻoe a hiki i kāu hoapili ke hāpai, pono ʻoe e hoʻohana i ka kaohi hānau kūpono i kāu wā e mālama ai a no 1 mahina ma hope o kāu hopena hope loa. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i duvelisib, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Duvelisib i ke fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā e lawe nei ʻoe i ka duvelisib a no ka liʻiliʻi o 1 mau mahina ma hope o kāu hopena hope loa.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Inā ʻoe e nalo i kahi mahele o ka duvelisib ma lalo o 6 mau hola, e lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai a laila lawe i ka lāʻau aʻe i ka manawa i hoʻopaʻa ʻia. Eia nō naʻe, inā ʻoe e nalo i kahi mahele ma mua o 6 mau hola, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Duvelisib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• ka luaʻi
• kōpaʻa
• luhi
• ʻeha poʻo
• ʻeleu a hui pū paha i ka ʻeha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• melemele nā ​​maka a i ʻole ka ʻili; abdominal eha; ʻehaʻeha a hoʻokahe paha i ka wehewehe ʻole ʻia; lilo o ka makemake ʻole; mimi melemele a ʻeleʻele paha; noho humuhumu; aiʻole kaʻeha ma kaʻaoʻao'ākau o luna o ka'ōpū

Hoʻokumu paha ʻo Duvelisib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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