ʻO Ivosidenib

Anter

• Ma mua o ka lawe ʻana iā ivosidenib,
• Hiki i nā Ivosidenib ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hiki iā Ivosidenib ke kumu i kahi hui koʻikoʻi a hoʻoweliweli paha i ke ola o nā ʻōuli i kapa ʻia he diffence syndrome. E nānā pono kāu kauka iā ʻoe e ʻike inā ke hoʻomohala nei ʻoe i kēia maʻi maʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: fiva, batukū, ʻūlū, loaʻa ke kaupaona hikiwawe, hoʻemi i ka urination, ka pehu ʻana o nā lima a me nā wāwae paha, ʻūpē a me ka lightheadedness, ka liʻiliʻi o ka hanu, a me ka pilikia o ka hanu. Kū paha kēia mau ʻōuli a 3 mau mahina ma hope o ka hoʻomaka ʻana o ka mālama ʻana me ivosidenib. I ka hōʻailona mua ke hoʻomohala nei ʻoe i ka maʻi hoʻokaʻawale, e kuhikuhi ana kāu kauka i nā lāʻau e mālama ai i ka maʻi, a e haʻi paha iā ʻoe e hoʻōki i ka lawe ʻana i ivosidenib no kekahi manawa.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua ma mua a i kou wā e mālama ai e nānā i ka pane o kou kino iā ivosidenib.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me ivosidenib a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) e kiʻi i ke alakaʻi Medication.

Hoʻohana ʻia ʻo Ivosidenib e mālama i kekahi ʻano o ka leukemia myeloid koʻikoʻi (AML; kahi ʻano o ka maʻi ʻaʻai e hoʻomaka i loko o nā keʻokeʻo koko keʻokeʻo) i hoʻi mai a i hoʻomaikaʻi ʻole paha ma hope o nā lāʻau ma mua. Hoʻohana ʻia ʻo Ivosidenib e mālama i kekahi ʻano AML i kekahi mau mākua ma mua o 75 mau makahiki ma ke ʻano he lapaʻau mua. Aia ʻo Ivosidenib i kahi papa o nā lāʻau lapaʻau cad IDH1 mea kāohi. Hana ia ma ka hoʻolohi a paʻa ʻana paha i ka ulu ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Ivosidenib ma ke ʻano he papa e lawe ma ka waha. Lawe mau ʻia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i kēlā me kēia lā. Hana ʻaʻole lawe iā ia me kahi meaʻai momona momona (e like me nā meaʻai palai a i ʻole meaʻai wikiwiki). Lawe iā ivosidenib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono iā ivosidenib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Inā luaʻi ʻoe ma hope o ka lawe ʻana i ivosidenib, mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau a i ʻole manawa kūmau a paʻa mau paha i kāu mālama ʻana me ivosidenib ma muli o kāu pane i ka lāʻau lapaʻau a i ʻole nā ​​hopena ʻē aʻe āu e ʻike ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana iā ivosidenib,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka ivosidenib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa ivosidenib. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono e ʻōlelo i kekahi o kēia mau mea: amiodarone (Nexterone, Pacerone), carbamazepine (Equetro, Tegretol, Teril, a me nā mea ʻē aʻe), clarithromycin, diltiazem (Cardizem, Cartia, Diltzac, Tiazac, a me nā mea ʻē aʻe) Symfi), erythromycin (Eryc), fluconazole (Diflucan), indinavir (Crixivan), itraconazole (Onmel, Sporanox, Tolsura), ketoconazole, oral contraceptives e like me kekahi ('birth control pills'), patches, and hormonal vaginal ring, nefazodone , nelfinavir (Viracept), nevirapine (Viramune), phenobarbital, phenytoin (Dilantin, Phenytek), pioglitazone (Actos), procainamide, quinidine (in Nuedexta), rifabutin (Mycobutin), rifampin (Rifadin, in Rifamate, in Ravamate, in Ravamate, in Ravamate, in Ravamate, in Ravamate, in Ravamate) (Norvir, ma Kaletra, ma Viekira), saquinavir (Fortovase, Invirase), telithromycin (Ketek), a me verapamil (Calan, Verelan, ma Tarka). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me ivosidenib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo keu ʻo St. John's Wort.
• e haʻi i kāu kauka inā ʻo ʻoe a ʻo kekahi paha o kou ʻohana a i ʻole loaʻa i kahi wā QT hoʻolōʻihi (kahi e hoʻonui ai i ka makaʻu o ka hoʻomohala ʻana i kahi puʻuwai kūpono ʻole e hoʻonāwaliwali ai ʻole make koke paha); inā i loaʻa iā ʻoe a i ʻole loaʻa i kahi puʻuwai lohi a i ʻole kaulike ʻole a i ʻole nā ​​pilikia puʻuwai ʻē aʻe; nā pae koko haʻahaʻa o ka sodium, potassium, a i ʻole magnesium; pilikia pilikia ʻōnaehana; maʻi maʻi ate, me cirrhosis; aiʻole inā ke loaʻa nei ʻoe i nā lāʻau lapaʻau dialysis a i ʻole inā i loaʻa iā ʻoe a loaʻa i kahi maʻi maʻi konohiki.
• e haʻi i kāu kauka inā hāpai ʻoe a hoʻolālā paha e hāpai, a i ʻole e hānai umauma ʻana. Pono ʻoe e ʻike i ka ivosidenib hiki ke hoʻemi i ka pono o nā kaola hormonal (nā lāʻau kaohi hānau, nā pāʻina, nā apo, a i ʻole nā ​​injection) ke lawe nei ʻoe i kēia lāʻau. E kamaʻilio me kāu kauka e pili ana i ka hoʻohana ʻana i kahi ʻano o ka kaohi hānau. Inā hāpai ʻoe i ka lawe ʻana iā ivosidenib, e kāhea koke i kāu kauka. Hiki iā Ivosidenib ke hōʻeha i ka fetal.
• e haʻi i kāu kauka inā e hānai ana i ka hānai. Mai hānai i ka wā o kāu mālama ʻana me ivosidenib a no 1 mau mahina ma hope o kāu hopena hope loa.

E kamaʻilio me kāu kauka e pili ana i ka ʻai ʻana i ka huaʻōlau a me ka inu ʻana i ka wai momona a ke lawe nei ʻoe i kēia lāʻau.

E hōʻoia e inu nui i ka wai a i ʻole nā ​​wai ʻē aʻe i kēlā me kēia lā ʻoiai ʻoe e lawe nei iā ivosidenib.

Inā loaʻa kāu mahele lāʻau aʻe i 12 mau hola a ʻoi paha, e lawe i ka lāʻau i hala i kou hoʻomanaʻo ʻana iā ia. Eia nō naʻe, inā e lawe ʻia ka lāʻau aʻe ma lalo o 12 mau hola, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i nā Ivosidenib ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻeha poʻo
• luhi
• ʻeha hui a ʻeha ʻeha paha
• pāhoehoe
• kōpaʻa
• ka luaʻi
• nausea
• nalo ʻai ʻole
• ʻeha o ka waha a me nā puʻupuʻu
• ʻeha ka ʻōpū

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• puʻupuʻu, uila, a maʻule paha
• nāwaliwali a i ʻole ke kaniʻuhū ʻana i nā wāwae, nā lima, a i ʻole ke kino kiʻekiʻe; numbness a ʻeha ma kekahi ʻaoʻao a i ʻole ʻelua ʻaoʻao o ke kino; nā loli i kou hiki ke ʻike, hoʻopā, lohe a ʻono paha; puhi a ʻaʻā Prickling sensation paha; a i ʻole paʻakikī i ka hanu ʻana
• ʻeha ka umauma

Hiki iā Ivosidenib ke hana i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E kauoha kāu kauka i kahi hoʻokolohua lab ma mua o kou hoʻomaka ʻana i kāu lāʻau e ʻike inā hiki ke mālama ʻia i kou maʻi ʻaʻai me ivosidenib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Tibsovo^®