Pākuʻi Durvalumab

Anter

• Ma mua o ka loaʻa ʻana o ka injection durvalumab,
• Hoʻokumu paha ʻo Durvalumab injection i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

Hoʻohana ʻia ʻo Durvalumab e mālama ai i ka maʻi ʻaʻai liʻiliʻi liʻiliʻi liʻiliʻi (NSCLC) i pāhola ʻia i nā mea pili kokoke a ʻaʻole hiki ke hemo ʻia e ke kaha ʻana akā ʻaʻole i ʻoi aku ka maikaʻi ma hope o ka mālama ʻia ʻana me nā lāʻau chemotherapy a me nā lāʻau radiation. Hoʻohana pū ʻia ʻo Durvalumab injection me ka etoposide (Etopophos) a me ka carboplatin a i ʻole cisplatin e mālama ai i ka maʻi ʻaʻa puʻupuʻu puʻupuʻu liʻiliʻi (ES-SCLC) i nā mākua i pāhola ʻia ka maʻi ʻaʻai ma nā akemāmā a me nā ʻāpana ʻē aʻe o ke kino. Aia ʻo Durvalumab injection i loko o ka papa o nā lāʻau i kapa ʻia he monoclonal antibodies. Hana ia ma ke kōkua ʻana i kāu ʻōnaehana pale e hoʻolohi a kū i ka ulu ʻana o nā hunaola maʻi ʻaʻai.

ʻO ke kōkō ʻana o Durvalumab ma ke ʻano he wai e hoʻokomo ʻia i loko o ke aa i 60 mau minuke e ke kauka a kahu hānai paha i kahi haukapila a i ʻole kahi wahi olakino. No ka mālama ʻana i ka maʻi ʻaʻai urothelial a i ʻole NSCLC, hāʻawi pinepine ʻia ia i kēlā me kēia 2 pule no ka mea ke koi aku kāu kauka iā ʻoe e loaʻa i ka lāʻau lapaʻau a i ʻole no NSCLC a i hoʻokahi makahiki. No ka mālama ʻana iā ES-SCLC, hāʻawi pinepine ʻia ia i kēlā me kēia 3 pule no 4 pōʻaiapuni me nā lāʻau ʻē aʻe, a laila hoʻokahi wale nō i kēlā me kēia 4 pule no ka mea ke koi aku kāu kauka iā ʻoe e mālama.

Hiki i ke kīpuna Durvalumab ke kumu i nā hopena koʻikoʻi a hoʻoweliweli paha i ke ola. E nānā pono kahi kauka a kahu hānai paha iā ʻoe ke loaʻa nei ʻoe i ka infusion a ma hope koke iho o ka infusion e hōʻoia ʻaʻole ʻoe i kahi hopena koʻikoʻi i ka lāʻau. E haʻi koke aku i kāu kauka a kahu hānai paha inā ʻike ʻoe i kekahi o nā ʻōuli e hiki ke hana ʻia ma hope a ma hope paha o ka infusion: haʻalulu a haʻalulu, ʻili, ʻūlū, flush, paʻakikī i ka hanu ʻana, pākī, kuni, maʻule, hoʻi a ʻeha ʻāʻī, a huʻā paha. o kou alo.

E hoʻolohi paha kāu kauka i kāu infusion, hoʻolohi a hoʻopau paha i kāu mālama ʻana me ke kī ʻana o ka durvalumab, a i ʻole mālama iā ʻoe me nā lāʻau hou aʻe e like me kāu pane i ka lāʻau a me nā hopena ʻē aʻe āu e ʻike ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka pepa ʻikepili a ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me ka inikolo durvalumab a i kēlā me kēia manawa ke loaʻa iā ʻoe kahi lāʻau. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka injection durvalumab,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka durvalumab, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hoʻohui i ka injection durvalumab. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā loaʻa iā ʻoe kahi transplant organ. E haʻi pū aku i kāu kauka inā loaʻa a loaʻa paha iā ʻoe kahi maʻi autoimmune (ke ʻano e hoʻouka ai ka ʻōnaehana pale i kahi ʻaoʻao olakino o ke kino) e like me ka maʻi o Crohn (ke ʻano e hoʻouka ai ka ʻōnaehana pale i ka uhi o ka ʻaoʻao digestive e hōʻeha ai i ka ʻeha, diarrhea, weight loss, and fever), ulcerative colitis (ke kumu o ka pehu ʻana a me nā ʻeha ma ka ʻaoʻao o ke kolona [ʻōpū nui] a me ke kīhā), a i ʻole lupus (ke ʻano e hoʻouka aku ai ka ʻōnaehana pale i nā aʻa a me nā ʻola me ka ʻili. nā hono, ke koko, a me nā puʻupaʻa); kekahi ʻano maʻi maʻi a i ʻole nā ​​pilikia hanu; aiʻole ka maʻi ate. E haʻi aku i kāu kauka inā mālama ʻia ʻoe i kēia manawa no kahi maʻi.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. ʻAʻole pono ʻoe e hāpai i ka wā e loaʻa ana iā ʻoe ka lāʻau ʻo durvalumab. Pono ʻoe e hoʻohana i ka kaohi hānau pono e pale i ka hāpai ʻana i kāu wā e mālama ai me ka hoʻopili ʻana o ka durvalumab a no 3 mau mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Inā hāpai ʻoe i ka loaʻa ʻana o ka injection durvalumab, e kāhea koke i kāu kauka. Hoʻopilikia paha ka piʻo Durvalumab i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū a i ʻole hoʻolālā e hānai. ʻAʻole pono ʻoe e hānai i ka wā e loaʻa ana ka puʻupuʻu durvalumab a no 3 mau mahina ma hope o kāu hopena hope loa.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Hoʻokumu paha ʻo Durvalumab injection i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻeha ka iwi a ʻeha paha
• pehu o kou mau lima a mau wāwae paha
• kōpaʻa

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka:

• ʻeha hou a ʻoi aku paha ka ʻeha, ʻeha o ka umauma, a me ka hanu ʻole
• melemele o kou mau maka a i ʻole ʻili, kahe ʻana o ke kahe a palu paha, hoʻemi i ka makemake, ʻeleʻele (ʻeleʻele) ka mimi, ʻeha ma ka ʻaoʻao ʻākau o luna o ka ʻōpū, nāwaliwali loa, nausea a i ʻole ka luaʻi
• diarrhea, ʻeha o ka ʻōpū, a ʻeleʻele paha, hoʻolāʻihi, pili a i ʻole nā ​​noho koko
• hoʻemi i ka urination, ke koko i ka mimi, ka pehu ʻana i kou mau kuʻekuʻe wāwae, hoʻoliʻiliʻi ka makemake
• fiva, batukū, haʻalulu, flu e like me nā ʻōuli, urination pinepine a ʻeha paha, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• ʻeha poʻo ʻole e hele aku a i ʻole poʻo poʻo poʻo ʻokoʻa paha; luhi loa; ka pohō kaumaha a loaʻa kālā paha; hoʻonui i ka pōloli a make wai paha; luuluulu a maule paha; ke anuanu, ka hohonu ʻana o ka leo, a i ʻole ka constipation; poho lauoho; nā loli i ke ʻano a me nā ʻano e like me ka hoʻoliʻiliʻi hoʻokau wahine, huhū, huikau, a hoʻopoina paha; nausea a i ʻole ka luaʻi; ʻeha ka ʻōpū
• ʻehu, ʻili, a ʻili hoʻi o ka ʻili
• ʻāʻī ʻoʻoleʻa
• pohihihi a ʻike pālua paha, a i ʻole nā ​​pilikia ʻike ʻē aʻe
• ʻulaʻula maka a ʻeha paha

Hoʻokumu paha ʻo Durvalumab injection i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha aku kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka injection durvalumab.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Imfinzi^®