Brigatinib

Anter

• Ma mua o ka lawe ʻana i brigatinib,
• Hoʻokumu paha ʻo Brigatinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ʻo Brigatinib e mālama i kekahi ʻano maʻi ʻaʻai liʻiliʻi liʻiliʻi liʻiliʻi (NSCLC) i pāhola ʻia i nā ʻāpana ʻē aʻe o nā kino. Aia ʻo Brigatinib i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o kahi protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hoʻolohi a hoʻopau paha i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Brigatinib ma ke ʻano he papa e lawe ma ka waha. Lawe mau ʻia me ka ʻai ʻole a ʻai ʻole hoʻokahi manawa i kēlā me kēia lā. Lawe i ka brigatinib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pololei i ka brigatinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai nahu a paopao iā lākou.

Inā luaʻi ʻoe ma hope o ka lawe ʻana i brigatinib, mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

E hoʻomaka paha kāu kauka iā ʻoe ma kahi haʻahaʻa o brigatinib a hoʻonui i kāu lāʻau ma hope o 7 mau lā o ka mālama ʻana.

Pono paha kāu kauka e hoʻopau i kahi manawa a kūpaʻa mau paha i kāu lāʻau a hōʻemi paha i kāu lāʻau o brigatinib a i ʻole nā ​​lāʻau ʻē aʻe āu e lawe nei, e pili ana i nā hopena i loaʻa iā ʻoe i kāu wā e mālama ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana. Mai hōʻoki i ka lawe ʻana i ka brigatinib me ke kamaʻilio ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i brigatinib,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka brigatinib, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa brigatinib. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E hōʻike pono i kekahi o kēia mau mea: antifungals e like me itraconazole (Onmel, Sporanox, Tolsura), ketoconazole, buprenorphine a me naloxone (Suboxone), carbamazepine (Equetro, Tegretol, Teril, a me nā mea ʻē aʻe) ), diltiazem (Cardizem, Cartia, Diltzac, kekahi), efavirenz (Sustiva, ma Atripla, Symfi), erythromycin (EES, Eryc, Erythrocin), indinavir (Crixivan), nefazodone, nelfinavir (Viracept), nevirapine (Viramept), nevirapine (Viramept), nevirapine (Viramept), nevirapine (Viramept), nevirapine (Viramept) ; phenytoin (Dilantin, Phenytek), pioglitazone (Actos, ma Actoplus Met, Duetact, Oseni), rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater), ritonavir (Norvir, ma Kaletra, Technivie, Viekira), sirolimus (Rapamune), tacrolimus (Astagraf, Envarsus, Prograf), a i ʻole verapamil (Calan, Verelan, ma Tarka). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me brigatinib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa paha iā ʻoe ke kiʻekiʻe o ke koko kiʻekiʻe; he puʻuwai puʻuwai diabetes a i ʻole nā ​​pilikia kō kō ʻē aʻe; aiʻole ka maʻi puʻuwai a i ʻole ate.
• e haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole hoʻolālā i ka makua kāne o kahi keiki. Hoʻopilikia paha ʻo Brigatinib i ka hana o nā mea pale hormonal (nā lāʻau kaohi o ka hānau ʻana, nā pāhoʻi, nā apo, nā implant, a i ʻole nā ​​injection), no laila ʻaʻole pono ʻoe e hoʻohana i kēia mau mea ma ke ʻano he ʻano hana wale no kou kaohi hānau i kāu wā e mālama ai. Pono ʻoe e hoʻohana i kahi kaohi hānau ʻole hormonal e like me ke ʻano pale (kahi mea e ālai i ka sperm mai ke komo ʻana i ka pūpū e like me ka condom a i ʻole diaphragm) E noi i kāu kauka e kōkua iā ʻoe e koho i kahi hana o ka kaohi hānau e holo pono nāu. Inā he wahine ʻoe, pono ʻoe e hoʻohana i ka hānau hānau ʻole hormonal i kou wā lapaʻau a no 4 mau mahina ma hope o kāu hopena hope loa. Inā he kāne ʻoe, pono ʻoe a me kāu pakanā wahine e hoʻohana i ka kaohi hānau i ka wā o kāu mālama ʻana a hoʻomau i ka hoʻohana ʻana i ka kaohi hānau no 3 mau mahina ma hope o kāu hopena hope loa. Hoʻopilikia paha ʻo Brigatinib i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā o kāu mālama ʻana me brigatinib a no 1 mau pule ma hope o kāu hopena hope loa.
• pono ʻoe e ʻike i kēia lāʻau i hoʻemi ai i ka momona i nā kāne. E kamaʻilio me kāu kauka e pili ana i nā pilikia o ka lawe ʻana i brigatinib.

Hōʻalo i ka ʻai ʻana i ka huaʻulu a me ka inu ʻana i ka wai momona a ke lawe nei ʻoe i ka brigatinib.

E haʻalele i ka lāʻau i haʻalele ʻia a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Inā makemake ʻoe e lawe i ka brigatinib no 14 mau lā a ʻoi aku paha, e kamaʻilio me kāu kauka ma mua o ka hoʻomaka ʻana e lawe hou. E hoʻomaka hou paha ʻoe i ka lawe ʻana i kahi mahele haʻahaʻa.

Hoʻokumu paha ʻo Brigatinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• pāhoehoe
• ka luaʻi
• kōpaʻa
• luhi
• hūwī
• ʻeha poʻo
• numbness, ʻeha, ʻūlū, a me ke ʻano wela i nā wāwae a i ʻole nā ​​lima
• ʻeha hope a hui pū paha
• nalo ʻai ʻole
• paʻakikī e hiamoe a hiamoe paha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• pōkole o ka hanu a paʻakikī hoʻi i ka hanu ʻana
• ʻeha ka umauma
• uha me ka ʻole o ka hemo
• fiva
• ʻeha poʻo, ʻūlū, uila, a me nāwaliwali paha
• ʻike hihi ʻole a pālua paha
• ke ʻike aku nei i nā kukuna uila
• ʻeha ka maka i kou mau maka
• ke ʻike nei iā '' floaters '' a i ʻole nā ​​specks liʻiliʻi
• make wai loa, urination pinepine, pololi loa, ʻike maka ʻole, a nāwaliwali paha
• ʻeha o ka ʻōpū o luna e pālahalaha i ka hope a i ʻole e ʻoi aku ka maikaʻi me ka ʻai ʻana; Kaumaha emi; aiʻole nausea
• puʻuwai a i ʻole kōkō puʻuwai
• ʻeha ʻeha, spasms, palupalu, a nāwaliwali paha

Hoʻokumu paha ʻo Brigatinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kahi hoʻokolohua lab ma mua o kou hoʻomaka ʻana i kāu lāʻau e ʻike inā hiki ke mālama ʻia i kou maʻi ʻaʻai me brigatinib. E kauoha nō hoʻi kāu kauka i kekahi mau hoʻokolohua lab a nānā i kou kaomi koko ma mua a i kou wā e mālama ai e nānā i ka pane o kou kino i ka brigatinib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Alunbrig^®