Atezolizumab Injection

Anter

• Hoʻohana ʻia ka pahu kui Atezolizumab:
• Ma mua o ka loaʻa ʻana o ka injection atezolizumab,
• Hoʻokumu paha ʻo Atezolizumab injection i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli e kāhea koke i kāu kauka a i ʻole e loaʻa i ka lāʻau lapaʻau olakino.

Hoʻohana ʻia ka pahu kui Atezolizumab:

• e mālama i kekahi ʻano o ka maʻi ʻaʻai urothelial (ka maʻi ʻaʻai o ka pale o ka maʻi ʻaʻai a me nā ʻāpana ʻē aʻe o ka maʻi urinary) i pālahalaha ʻia a i ʻole hiki ʻole ke hemo ʻia e ke ʻoki ʻana i ka poʻe i hiki ʻole ke loaʻa ka chemotherapy platinum (carboplatin, cisplatin),
• hoʻokahi a i ʻole me nā lāʻau chemotherapy ʻē aʻe ma ke ʻano he lapaʻau mua no kekahi ʻano o ka maʻi ʻaʻai liʻiliʻi liʻiliʻi ʻole (NSCLC) i pāhola ʻia i nā ʻāpana ʻē aʻe o ke kino.
• e mālama i kekahi ʻano o ka NSCLC i pālahalaha ʻia i nā ʻāpana ʻē aʻe o ke kino a ua hōʻino ʻia i ka wā a ma hope paha o ka mālama ʻana me nā lāʻau chemotherapy ʻē aʻe,
• me nā lāʻau chemotherapy ʻē aʻe ma ke ʻano he lapaʻau mua no kekahi ʻano maʻi ʻaʻai liʻiliʻi liʻiliʻi (SCLC) i pāhola ʻia i loko o ka akemāmā a i nā ʻāpana ʻē aʻe paha o ke kino.
• me nā lāʻau chemotherapy ʻē aʻe ma ke ʻano he lapaʻau no kekahi ʻano o ka maʻi ʻaʻai umauma i pāhola ʻia i nā ʻāpana ʻē aʻe o ke kino a i ʻole hiki ʻole ke wehe ʻia e ke ʻoki kino.
• me ka bevacizumab (Avastin) e mālama ai i ka maʻi hepocellular (HCC) i pālahalaha a i ʻole hiki ke hemo ʻia e ke ʻoki ʻana i ka poʻe i loaʻa ʻole ka chemotherapy, a
• i ka hui pū ʻana me cobimetinib (Cotellic) a me vemurafenib (Zelboraf) e mālama i kekahi mau ʻano melanoma (kahi ʻano maʻi ʻaʻai ʻili) i pālahalaha a i ʻole hiki ke hemo ʻia e ka ʻoki kino.

Aia ka injection Atezolizumab i kahi papa o nā lāʻau i kapa ʻia he monoclonal antibodies. Hana ia ma ke kāpae ʻana i ka hana o kekahi protein i nā hunaola maʻi ʻaʻai. Kōkua kēia i ka ʻōnaehana pale o ke kanaka e kaua aku i nā hunaola maʻi ʻaʻai, a kōkua i ka lohi o ka ulu ʻana o ka tumo.

Hele mai ka pahu Atezolizumab me he wai lā e hoʻokomo ʻia i loko o ke aa ma mua o 30 a 60 mau minuke e ke kauka a kahu hānai paha i kahi haukapila a i ʻole kahi wahi olakino. Ke hoʻohana ʻia ka injection atezolizumab e mālama ai i ka maʻi ʻaʻai urothelial, NSCLC, SCLC, a i ʻole ka maʻi kanesa hepatocellular, ʻimi pinepine ʻia ia i kēlā me kēia 2, 3, a i ʻole 4 mau pule e like me kāu kauka no ka mea ke koi aku kāu kauka e loaʻa iā ʻoe ka lāʻau. Ke hoʻohana ʻia ka pahu kui atezolizumab e mālama i ka maʻi ʻaʻai o ka umauma ua injected maʻamau ia i nā lā 1 a me 15 ma ke ʻano he mahele o ka pōʻaiapuni 28 mau lā. Ke hoʻohana ʻia ka injection atezolizumab e mālama i ka melanoma, ua injected mau ia i kēlā me kēia 2 pule. Aia ka lōʻihi o kāu mālama ʻana i ka maikaʻi o ka pane ʻana o kou kino i ka lāʻau a me nā hopena ʻaoʻao āu e ʻike ai.

Hiki i ke kīpuna Atezolizumab ke hana i nā hopena koʻikoʻi i ka wā o ka hoʻokomo ʻana o ka lāʻau. E nānā pono kahi kauka a kahu hānai paha iā ʻoe ke loaʻa iā ʻoe ka lāʻau. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e haʻi koke aku i kāu kauka: flushing, fever, chills, haʻalulu, hoʻoluhi, ʻano maʻule, pōkole o ka hanu, paʻakikī i ka hanu ʻana, ʻili, ʻūlū, ʻāʻī a ʻāʻī hoʻi, a i ʻole pehu o ka maka a i ʻole nā ​​lehelehe .

Pono paha kāu kauka e hoʻolohi i kāu infusion, hoʻolohi a hoʻopau paha i kāu lāʻau lapaʻau, a mālama iā ʻoe me nā lāʻau ʻē aʻe inā ʻike ʻoe i kekahi mau hopena ʻaoʻao. E pono e haʻi aku i kāu kauka i kou ʻano i kou wā e mālama ai me ka injection atezolizumab.

E hāʻawi aku kāu kauka a mea kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me atezolizumab injection a i kēlā me kēia manawa ke loaʻa iā ʻoe ka lāʻau. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka injection atezolizumab,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i atezolizumab, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka inezolizumab injection. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka inā mālama ʻia ʻoe no kahi maʻi. E haʻi pū aku i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i kahi transplant ʻōnaehana; nā pilikia o ka hanu a me ka hanu ʻana; maʻi e hoʻopili i kou ʻōnaehana hopohopo e like me myasthenia gravis (kahi maʻi o ka ʻōnaehana hopohopo e kumu ai i ka nāwaliwali o nā mākala) a i ʻole ʻo Guillain-Barre Syndrome (nāwaliwali, ʻalalā, a me ka hiki ʻole o ka palapū ma muli o ka ʻino o ke aʻalolo. maʻi autoimmune (ke ʻano e hoʻouka ai ka ʻōnaehana pale i kahi ʻaoʻao olakino o ke kino) e like me ka maʻi o Crohn (ke ʻano e hoʻouka aku ai ka ʻōnaehana pale i ka uhi ʻana o ka mahele digestive e hōʻeha ai i ka maʻi, diarrhea, weight loss, and fever), ulcerative colitis ( ke kumu e kū ai ka pehu a me nā ʻeha i ka uhi ʻana o ke kolona [ʻōpū nui] a me ke kīhā) a i ʻole ka lupus (ke ʻano e hoʻouka aku ai ka ʻōnaehana pale i nā aʻa a me nā ʻokena e like me ka ʻili, nā hono, ke koko, a me nā puʻupaʻa); aiʻole ka maʻi ate.
• e haʻi i kāu kauka inā hāpai ʻoe, a i ʻole hoʻolālā e hāpai. ʻAʻole pono ʻoe e hāpai i ka wā o kāu mālama ʻana a no 5 mau mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i kāu wā o kāu mālama ʻana. Inā hāpai ʻoe i ka loaʻa ʻana o ka injection atezolizumab, kāhea koke i kāu kauka.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. E haʻi paha kāu kauka iā ʻoe ʻaʻole e hānai i ka wā o kāu mālama ʻana a no 5 mau mahina ma hope o kāu kau hope loa.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Hoʻokumu paha ʻo Atezolizumab injection i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• kua, ʻāʻī, a ʻeha pū paha
• hūwī
• ʻūlili
• pilikia e hiamoe ana a hiamoe paha
• luhi loa
• ʻili mae
• ʻano anuanu
• pehu o nā lima
• nalo ʻai ʻole
• nausea
• ka luaʻi
• pāhoehoe
• kōpaʻa
• poho lauoho
• ka hohonu ʻana o ka leo a i ʻole ke kani ʻana
• loaʻa kaupaona

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli e kāhea koke i kāu kauka a i ʻole e loaʻa i ka lāʻau lapaʻau olakino.

• diarrhea, ʻeha o ka ʻōpū, ke koko a i ʻole ka mucus i loko o ka pahu, a i ʻole ka pāleo ʻeleʻele, paleko, ka noho
• ʻeha mau e hoʻomaka i ka hema hema a i ʻole ka waena o ka ʻōpū akā hiki ke pālahalaha i ke kua, ke kuni, kahoʻi, ka luaʻi
• kōpū me ka ʻōpū ʻōpū a ʻōhū paha
• fiva, ʻāʻī puʻupuʻu, ʻūhā, haʻalulu, ʻōuli e like me ka flu, pinepine, wikiwiki, paʻakikī, a i ʻole ka mimiki ʻeha, a i ʻole nā ​​hōʻailona ʻino ʻē aʻe.
• mimi, ʻulaʻula, a i ʻole mimi eleele ʻeleʻele
• hoʻemi i ka urination, ka pehu ʻana i kou mau wāwae, nā kuʻekuʻe wāwae, a me nā wāwae
• mahana, ʻulaʻula, pehu, a wāwae palupalu paha
• hou a hōʻino paha i ka ʻeha a maʻi paha ke koko, ka liʻiliʻi o ka hanu, a me ka ʻeha o ka umauma
• melemele o ka ʻili a i ʻole nā ​​maka, māluhiluhi nui loa, kahe ʻana o ke kōkō a palū paha paha, pākī a luaʻi paha, ʻeha o ka ʻōpū, mimi ʻeleʻele, hoʻemi i ka makemake.
• ʻeha poʻo ʻole ʻole e hele a i ʻole poʻo poʻo poʻo ʻole, hoʻonui i ka make wai a i ʻole ka urination, hoʻololi i ka hihiʻo, hoʻemi i ka hoʻokele wahine
• wikiwiki ka puʻuwai, hoʻonui i ka makemake, lilo kaumaha koke, ʻano wela, loli ke ʻano
• nāwaliwali o ka mākala, numbness a i ʻole tingling i kou mau lima, nā wāwae, nā lima, a i ʻole nā ​​wāwae, ke kuni, ka huikau, nā loli i ke ʻano a me ke ʻano, ʻike i ka mālamalama, ʻāʻī ʻoʻoleʻa
• blurry a ʻike pālua paha, a i ʻole nā ​​pilikia ʻike ʻē aʻe, ʻeha o ka maka a ʻulaʻula paha
• ʻūpī a palupalu paha
• ʻoi aku ka pōloli a make wai paha ma mua o ka maʻamau, hoʻonui i ka urination, ka luhi nui loa, nāwaliwali, ka hanu e ʻaʻala i ka hua
• nā loli i ke ʻano a me nā lawena (hoʻemi i ka hoʻokau wahine, hoʻonāukiuki, huikau, a me ka hoʻopoina)
• ʻeha o ka umauma, ka pōkole o ka hanu, ka puʻuwai puʻuwai ʻole, ka pehu ʻana o nā kuʻekuʻe wāwae, ʻaʻole hiki ke hoʻoikaika e like me ʻoe ma mua.

Hoʻokumu paha ʻo Atezolizumab injection i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab a ma mua a i kou wā e mālama ai me ka injection atezolizumab e nānā i ka pane o kou kino i ka lāʻau. No kekahi mau kūlana, e kauoha kāu kauka i kahi hoʻokolohua hoʻokolohua ma mua o kou hoʻomaka ʻana i kāu lāʻau e ʻike inā hiki ke mālama ʻia i kou maʻi ʻaʻai me atezolizumab.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Tecentriq^®