ʻO Sofosbuvir lāua ʻo Velpatasvir

Anter

• Ma mua o ka lawe ʻana i sofosbuvir a me velpatasvir,
• ʻO Sofosbuvir a me velpatasvir ke kumu o nā hopena. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

Ua hele a maʻi paha ʻoe i ka maʻi hepatitis B (kahi maʻi i hoʻopili i ke ake a hōʻeha paha i ka ate), akā ʻaʻohe o nā ʻōuli o ka maʻi. I kēia hihia, ʻo ka lawe ʻana i ka hui o sofosbuvir a me velpatasvir hiki ke hoʻonui i ka makaʻu e lilo i kou maʻi a ʻoi aku paha ka weliweli a e hoʻomohala ʻoe i nā ʻōuli. E haʻi i kāu kauka inā loaʻa a loaʻa paha iā ʻoe i ka maʻi maʻi maʻi hepatitis B. E kauoha aku kāu kauka i kahi hoʻokolohua koko e ʻike inā loaʻa a loaʻa paha iā ʻoe i ka maʻi hepitis B. E nānā pū kāu kauka iā ʻoe no nā hōʻailona o ka maʻi hepatitis B i ka manawa a no kekahi mau mahina ma hope o kāu lapaʻau. Inā pono, hiki i kāu kauka ke hāʻawi iā ʻoe i ka lāʻau e mālama ai i kēia maʻi ma mua a i kou wā o ka mālama ʻana me ka hui ʻana o sofosbuvir a me velpatasvir. Inā ʻoe e ʻike i kekahi o nā ʻōuli ma hope a i ʻole a ma hope paha o kāu lapaʻau ʻana, e kāhea koke aku i kāu kauka: luhi nui, melemele o ka ʻili a i ʻole nā ​​maka, lilo i ka makemake ʻole, nausea a i ʻole ka luaʻi, nā pale pale, ʻeha o ka ʻōpū, a me ka mimi ʻeleʻele.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. Hiki paha i kāu kauka ke kauoha i kekahi mau hoʻokolohua ma mua, i ka wā, a ma hope o kāu mālama ʻana e nānā i ka pane o kou kino i ka hui pū ʻana o sofosbuvir a me velpatasvir.

E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i ka hui o sofosbuvir a me velpatasvir.

Hoʻohana wale ʻia ka hui ʻana o sofosbuvir a me velpatasvir a i ʻole me ribavirin (Copegus, Rebetol, Ribasphere) e mālama ai i ka maʻi hepatitis C mau (kahi maʻi viral e hoʻomau nei e hōʻino ai i ke ake) i nā mākua a me nā keiki 6 mau makahiki a ʻoi paha a i kaupaona ma ka liʻiliʻi 37 paona (17 kg). Aia ʻo Sofosbuvir i kahi papa o nā lāʻau antiviral i kapa ʻia he nucleotide hepatitis C virus (HCV) NS5B polymerase inhibitors. Aia ʻo Velpatasvir i loko o ka papa o nā lāʻau antiviral i kapa ʻia ʻo HCV NS5A replication complex inhibitors. Hana ka hui pū ʻana o sofosbuvir a me velpatasvir ma ka hoʻōki ʻana i ka maʻi nāna e hoʻolauna ka maʻi hepatitis C i loko o ke kino.

ʻO ka hui pū ʻana o sofosbuvir a me velpatasvir hele mai ma ke ʻano he papa e lawe ʻia e ka waha. Lawe ʻia ia me ka ʻole a me ka ʻole o ka ʻai i hoʻokahi manawa i ka lā no 12 mau pule. Lawe iā sofosbuvir a me velpatasvir ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono iā sofosbuvir a me velpatasvir e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E hoʻomau i ka lawe sofosbuvir a me velpatasvir ʻoiai inā maikaʻi ʻoe. Mai kū i ka lawe sofosbuvir a me velpatasvir me ke kamaʻilio ʻole ʻana me kāu kauka.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i sofosbuvir a me velpatasvir,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka sofosbuvir, velpatasvir, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā papa sofosbuvir a me velpatasvir E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi aku i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻaiʻai āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: amiodarone (Nexterone, Pacerone); atorvastatin (Lipitor, ma Caduet); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); digoxin (Lanoxin); efavirenz (Sustiva, i Atripla); oxcarbazepine (Oxtellar, Trileptal); phenobarbital; phenytoin (Dilantin, Phenytek); nā mea pale proton-pump e like me dexlansoprazole (Dexilant), esomeprazole (Nexium, ma Vimovo), lansoprazole (Prevacid, i Prevpac), omeprazole (Prilosec, Zegerid), pantoprazole (Protonix), a me rabeprazole (AcipHex): rifabutin rifampin (Rifadin, Rimactane, ma Rifamate, Rifater); rifapentine (Priftin); rosuvastatin (Crestor); tenofovir DF (Viread, ma Atripla, Complera, Stribild, Truvada, nā mea ʻē aʻe); tipranavir (Aptivus) ke lawe ʻia me ritonavir (Norvir); topotecan (Hycamtin); a me warfarin (Coumadin, Jantoven). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Hiki paha i nā lāʻau ʻē aʻe ke launa pū me sofosbuvir a me velpatasvir, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• inā ʻoe e lawe i nā antacids, lawe iā lākou i 4 mau hola ma mua a i ʻole 4 mau hola ma hope o sofosbuvir a me velpatasvir.
• e haʻi i kāu kauka inā e lawe ana ʻoe i ka lāʻau no ka palaka ʻole ʻana, ka ʻū ʻana o ka puʻuwai, a i ʻole nā ​​maʻi maʻi hē₂ blockers) e like me cimetidine, ranitidine (Zantac), famotidine (Pepcid, ma Duexis), a i ʻole nizatidine. E haʻi paha kāu kauka iā ʻoe e lawe i kēia lāʻau i 12 mau hola ma mua a i ʻole 12 mau hola ma hope o ka sofosbuvir a me ka velpatasvir, a i ʻole ma ka manawa like e lawe ai iā sofosbuvir a me velpatasvir.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa iā ʻoe ka maʻi pale maʻi (HIV), a i ʻole loaʻa kekahi ʻano o ka pilikia ate ma mua o ka hepatitis C.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole e hānai umauma ana. Inā hāpai ʻoe i ka lawe ʻana iā sofosbuvir a me velpatasvir, e kāhea i kāu kauka.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

ʻO Sofosbuvir a me velpatasvir ke kumu o nā hopena. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• hūwī
• nele i ka ikaika
• huhū
• kaumaha

ʻO Sofosbuvir a me velpatasvir ke kumu o nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Epclusa^®