Mea Kākau: Virginia Floyd
Lā O Ka Hana: 12 Aukake 2021
HōʻAno Hou I Ka Lā: 17 Nowemapa 2024
Anonim
Talimogene Laherparepvec (T-VEC): Intrahepatic Injection Procedures
Wikiō: Talimogene Laherparepvec (T-VEC): Intrahepatic Injection Procedures

Anter

Hoʻohana ʻia ʻo Talimogene laherparepvec injection e mālama i kekahi mau melanoma (kahi ʻano maʻi ʻaʻai ʻili) ʻaʻole hiki ke hemo ʻia i ka ʻokiʻoki a hoʻi mai paha ma hope o ka mālama ʻia ʻana me ke ʻoki. Aia ʻo Talimogene laherparepvec i kahi papa o nā lāʻau i kapa ʻia he mau virus oncolytic. He ʻano nāwaliwali a loli hoʻi ʻo Herpes Simplex Virus Type I (HSV-1 'cold sore virus') e hana nei ma ke kōkua ʻana e pepehi i nā hunaola maʻi ʻaʻai.

Hele mai ka injection ʻo Talimogene laherparepvec ma ke ʻano he wehe (wai) e ʻimi ʻia e ke kauka a kahu hānai paha i kahi keʻena olakino. E hoʻopili pono kāu kauka i ka lāʻau i loko o nā tumors i luna o kou ʻili, ma lalo pono o kou ʻili, a i ʻole nā ​​lymph node. E loaʻa iā ʻoe i ka lua o ka mālama 3 mau hebedoma ma hope o ka hana mua, a laila i kēlā me kēia 2 mau pule ma hope. Pili ka lōʻihi o ka mālama ʻana i ka maikaʻi o ka pane ʻana o kou tumors i ka lāʻau. ʻAʻole kiki paha kāu kauka i nā tumors āpau i kēlā me kēia kipa.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Kauka Lapaʻau) ke hoʻomaka ʻoe i ka lāʻau me talimogene laherparepvec a i kēlā me kēia manawa ke loaʻa ʻoe i nā injection. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.


Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka loaʻa ʻana o ka talimogene laherparepvec injection,

  • e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka talimogene laherparepvec, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i ka inikua talimogene laherparepvec. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
  • e haʻi i kāu kauka inā lawe ʻoe i nā lāʻau e hoʻonāwaliwali ai i kou ʻōnaehana pale pale e like me antithymositte globulin (Atgam, Thymoglobulin), azathioprine (Azasan, Imuran), basiliximab (Simulect), belatacept (Nulojix), belimumab (Benlysta), cortisone, cyclosporine ( ʻO Gengraf, Neoral, Sandimmune), dexamethasone, fludrocortisone, methotrexate (Otrexup, Rasuvo, Trexall), methylprednisolone (Depo-medrol, Medrol, Solu-medrol), mycophenolate mofetil (Cellcept), prednisolone (Flopredone, Orapred, Rayos), sirolimus (Rapamune), a me tacrolimus (Astagraf XL, Prograf, Envarsus XR). He nui nā lāʻau ʻē aʻe e hoʻonāwaliwali paha i kāu ʻōnaehana pale, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa. E haʻi paha kāu kauka iā ʻoe ʻaʻole e loaʻa ka talimogene laherparepvec inā ʻoe e lawe i hoʻokahi a ʻoi paha o kēia mau lāʻau.
  • e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E ʻōlelo pono i kekahi o kēia mau mea: nā lāʻau antiviral e like me acyclovir (Sitavig, Zovirax), cidofovir, docosanol (Abreva), famciclovir (Famvir), foscarnet (Foscavir), ganciclovir (Cytovene), penciclovir (Denavirine (trifl), trifl Viroptic), valacyclovir (Valtrex), a me valganciclovir (Valcyte). Hoʻopili paha kēia mau lāʻau i ka maikaʻi o ka talimogene laherparepvec e hana ai iā ʻoe.
  • e haʻi i kāu kauka inā loaʻa a loaʻa paha iā ʻoe ka maʻi leukemia (maʻi ʻaʻai o nā aʻa koko keʻokeʻo), lymphoma (maʻi ʻaʻai o kahi ʻāpana o ka ʻōnaehana pale pale), maʻi hoʻomaʻemaʻe kanaka (HIV), loaʻa i ka maʻi maʻi maʻi (AIDS), a i ʻole kekahi ʻanoʻano ʻo ia ke kumu o ka nāwaliwali o ka pale. ʻAʻole paha makemake kāu kauka iā ʻoe e loaʻa ʻole ka puʻupuʻu talimogene laherparepvec.
  • e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole ua mālama mua ʻia ʻoe i ka radiation radiation ma kahi o nā tuman melanoma, myeloma maha (maʻi ʻaʻai o nā hunaola plasma i loko o ka iwi iwi), kekahi ʻano maʻi autoimmune (nā kūlana e hoʻouka ai ka ʻōnaehana pale i nā ʻāpana olakino o ke kino a hana i ka ʻeha, ka pehu ʻana, a me nā pohō), a i ʻole inā pili pili loa ʻoe me kekahi mea hāpai a i ʻole nāwaliwali nāwaliwali.
  • E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a i ʻole e hānai umauma ana. ʻAʻole pono ʻoe e hāpai i ka wā o kāu mālama ʻana me ka injection talimogene laherparepvec. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i kāu wā o kāu mālama ʻana. Inā hāpai ʻoe i ka loaʻa ʻana o ka inikua talimogene laherparepvec, e kelepona koke i kāu kauka. Hoʻopilikia paha ka puʻupuʻu Talimogene laherparepvec i ka fetus.
  • pono ʻoe e ʻike aia i loko o ka talimogene laherparepvec injection kahi maʻi virus i hiki ke pālahalaha a lele i nā poʻe ʻē aʻe. E akahele ʻoe i ka uhi ʻana i nā pūnaewele i hoʻopili ʻia me nā bandages airtight a me ka wai ʻole no 1 mau pule ma hope o kēlā me kēia lapaʻau, a ʻoi aku paha ka lōʻihi inā e kahe ana ka pūnaewele injection. Inā hemo a hāʻule paha nā kaula, e hoʻoliʻiliʻi koke. Pono ʻoe e hoʻohana i nā mīkina lima lope a i ʻole ka hopena ma ka hoʻopaʻa ʻana i nā pūnaewele i hoʻokomo ʻia. E hoʻokomo pono i nā mea hoʻomaʻemaʻe, nā mīkina lima, a me nā bandages i hoʻohana ʻia no nā pūnaewele i hoʻokomo ʻia i loko o kahi ʻeke ea i hoʻopaʻa ʻia a hoʻolei aku iā lākou i loko o nā ʻōpala.
  • ʻaʻole ʻoe e hoʻopā a wili paha i nā pūnaewele i hoʻokomo ʻia a i ʻole nā ​​kaula. Hiki i kēia ke pāhola i ka maʻi ma ka lāʻau talimogene laherparepvec i nā ʻāpana ʻē aʻe o kou kino. E akahele ka poʻe a puni ʻoe ʻaʻole e hele pololei i ka launa ʻana me kāu mau pūnaewele injection, bandages, a i ʻole nā ​​wai o ke kino. Kāhea koke i kāu kauka inā ʻoe, a i ʻole kekahi mea e hoʻopuni ana iā ʻoe, e hoʻomohala i nā maʻi o ka maʻi herpes;: ʻeha, puhi ʻana, a i ʻole ke kani ʻana i ka pūpū e kou waha, genitalia, manamana lima, a pepeiao paha; ʻeha o ka maka, ʻulaʻula, a haehae paha; ʻike hihi; ʻike i ka mālamalama; nāwaliwali i nā lima a me nā wāwae; hiamoe nui loa; a huikau paha o ka noʻonoʻo.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.


Hoʻokumu paha ʻo Talimogene laherparepvec i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

  • luhi laha ʻole
  • nausea
  • ka luaʻi
  • pāhoehoe
  • kōpaʻa
  • abdominal eha
  • ʻeha poʻo
  • ʻūpā
  • Kaumaha emi
  • maloʻo, māwae, ʻimi, ʻili ʻili
  • ʻehaʻeha a ʻeha pū paha
  • ʻeha ma nā lima a me nā wāwae
  • lohi ka hoʻōla ʻana i nā pūnaewele injection
  • ʻeha ma nā pūnaewele injection

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻĀLU MAKAHIKI kūikawā, e kāhea koke i kāu kauka:

  • ka hanu ʻana a i ʻole nā ​​pilikia hanu ʻē aʻe
  • ʻūhā
  • ʻākala, ʻāpala cola, a i ʻole mimi foamy
  • pehu o ka maka, ka lima, ka wāwae a i ʻole ka ʻōpū
  • nalowale ke kala i kou ʻili, lauoho, a i ʻole nā ​​maka
  • mehana, ʻulaʻula, pehu, a ʻeha ʻeha paha e pili ana i kahi o ka injection
  • fiva, ʻeha ka ʻāʻī, haʻalulu, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
  • nā mea make a i ʻole nā ​​ʻeha hāmama ma nā tumors i injected

Hoʻokumu paha ʻo Talimogene laherparepvec injection i nā hopena ʻē aʻe. Kāhea i kāu kauka inā loaʻa iā ʻoe kekahi pilikia maʻamau i ka loaʻa ʻana o kēia lāʻau.


Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mālama i nā manawa āpau me kāu kauka.

E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka talimogene laherparepvec injection.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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  • T-Vec
Nānā Hou - 02/15/2016

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