ʻO Trifluridine lāua ʻo Tipiracil

Anter

• Ma mua o ka lawe ʻana i trifluridine a me tipiracil,
• Hiki i ka Trifluridine a me ka tipiracil ke kumu i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli e kāhea koke i kāu kauka a i ʻole e loaʻa i ka lāʻau lapaʻau olakino.

Hoʻohana ʻia ka hui ʻana o trifluridine a me tipiracil e mālama ai i ka kolone (ʻōpū nui) a i ʻole ka maʻi ʻaʻai pololei i pāhola ʻia i nā ʻāpana ʻē aʻe o ke kino i ka poʻe i mālama ʻia me nā lāʻau chemotherapy ʻē aʻe a i ʻole hiki ke loaʻa i kēia mau lāʻau chemotherapy. Hoʻohana ʻia ka hui ʻana o trifluridine a me tipiracil e mālama i kekahi ʻano o ka maʻi ʻaʻai o ka ʻōpū a i ʻole ka maʻi ʻaʻai i loaʻa ma kahi e hui ai ka ʻōpū me ka esophagus (ka paipu ma waena o ka ʻāʻī a me ka ʻōpū) i pāhola ʻia i nā ʻāpana ʻē aʻe o ke kino i ka poʻe i loaʻa ua loaʻa ʻelua mau lāʻau chemotherapy ʻē aʻe. Aia ʻo Trifluridine i loko o ka papa o nā lāʻau i kapa ʻia he like nukleoside analogs me thymidine. Hana ia ma ka hoʻōki ʻana i ka ulu ʻana o nā hunaola maʻi ʻaʻai. Aia ʻo Tipiracil i loko o ka papa o nā lāʻau i kapa ʻia nā thymidine phosphorylase inhibitors. Hana ia ma ka hoʻolōʻihi ʻana i ka haki ʻana o trifluridine e ke kino.

ʻO ka hui pū ʻana o trifluridine a me tipiracil e hele mai ma ke ʻano he papa e lawe ʻia e ka waha. Lawe ʻia ia i ʻelua mau manawa i ka lā me ka meaʻai no 5 mau lā ma ka lālani, a ukali ʻia e kahi lā hoʻomaha 2 lā. Hoʻomaʻa hou ʻia kēia papa hana hana a laila ukali ʻia e kahi hoʻomaha he 2 mau pule. E hana hou paha kēia pōʻaiapuni 28 mau lā e kaukaʻi ʻia i ka maikaʻi o ka hana ʻana o kēia lāʻau iā ʻoe a me nā hopena ʻaoʻao āu e ʻike ai. E lawe i ka trifluridine a me ka tipiracil ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i ka trifluridine a me ka tipiracil e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Hele mai ʻo Trifluridine a me tipiracil papa i ʻelua mau ikaika ʻokoʻa. Makemake paha kāu kauka iā ʻoe e lawe i kahi hui o nā ikaika ʻelua o nā papa e hoʻopau ai i kāu kau palena. E ʻike pono i ke ʻano o kēlā me kēia ʻano o ka papa ʻaina a ehia āu e lawe ai i kēlā me kēia. E noi i kāu kauka a kauka paha inā he nīnau kāu.

Hiki i kāu kauka ke hoʻolohi i kāu lāʻau a hōʻemi paha i kāu lāʻau o trifluridine a me tipiracil kaukaʻi ʻia i nā hopena ʻaoʻao āu e ʻike ai. E kamaʻilio pono i kāu kauka e pili ana i kou ʻano i kou wā e mālama ai. Mai hōʻoki i ka lawe ʻana i trifluridine a me tipiracil me ka walaʻau ʻole ʻana me kāu kauka.

E holoi i kou mau lima ma hope o ka lawelawe ʻana i nā papa trifluridine a me tipiracil. Inā lawelawe kekahi i kāu pākana trifluridine a me tipiracil, pono lākou e komo i nā mīkina lima a i ʻole ka hopena paha i pili ʻole ko lākou ʻili me nā papa.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i trifluridine a me tipiracil,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka trifluridine a me ka tipiracil, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o ka papa trifluridine a me ka tipiracil. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau he aha nā lāʻau lapaʻau a me nā lāʻau ʻole i kuhikuhi ʻia, nā wikamina, nā mea hoʻopihaʻai, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe
• e haʻi i kāu kauka inā he 65 kou mau makahiki a ʻoi paha, a i ʻole loaʻa a loaʻa paha ʻoe i ka maʻi ate a me nā puʻupaʻa.
• E haʻi i kāu kauka inā hāpai ʻoe, e hoʻolālā e hāpai, a inā ʻoe e hoʻolālā i kahi keiki i kahi keiki. ʻAʻole pono ʻoe a ʻo kāu hoa paha e hāpai i ka wā o kāu mālama ʻana me trifluridine a me tipiracil. Inā he wahine ʻoe, pono ʻoe e hoʻokolohua hāpai ma mua o kou hoʻomaka ʻana i ka lāʻau, a pono ʻoe e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i kāu wā lapaʻau a no 6 mau mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā ʻano hana hānau hiki iā ʻoe ke hoʻohana i kāu wā o kāu mālama ʻana. Inā he kāne ʻoe a hiki i kāu pakanā ke hāpai, pono ʻoe e hoʻohana i kahi pale pale i ka wā e lawe ana i kēia lāʻau, a no 3 mau mahina ma hope o kāu lapaʻau. Inā hāpai ʻoe a i ʻole kāu pakanā ʻoiai ʻoe e loaʻa ana iā trifluridine a me tipiracil, e kāhea koke i kāu kauka. Hiki iā Trifluridine a me tipiracil ke hōʻeha i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. E haʻi paha kāu kauka iā ʻoe ʻaʻole e hānai i ka wā o kāu mālama ʻana a no 1 lā ma hope o kāu kau hope loa.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

Inā ʻike ʻoe i kahi mahele o trifluridine a me tipiracil, mai lawe i kahi lāʻau ʻē aʻe e pani ai no ka lāʻau i hala. Kāhea i kāu kauka no nā ʻōkuhi e pili ana i ka mea e hana ai no kahi lāʻau i hala.

Hiki i ka Trifluridine a me ka tipiracil ke kumu i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• poho lauoho
• hoʻololi i ke ʻano o ka ʻono o nā mea
• nalo ʻai ʻole
• ʻehaʻeha o ka waha a huʻu paha i loko o ka waha
• nele i ka ikaika
• luhi nui loa

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli e kāhea koke i kāu kauka a i ʻole e loaʻa i ka lāʻau lapaʻau olakino.

• fiva, ʻehaʻeha o ke kino, haʻalulu, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• nausea, ka luaʻi, diarrhea, a i ʻole ka ʻeha o ka ʻōpū nui loa a i ʻole hele aku
• nāwaliwali a me ka pōkole o ka hanu ke hoʻohana
• ʻili mae
• ʻeha ka umauma
• ʻeha me ka hanu hohonu
• kahe ana ke koko
• kahe koko ʻole ʻana a palapū paha

Hoʻokumu paha ʻo Trifluridine a me tipiracil i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi.E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Inā ua mālama ʻoe i kēia lāʻau i waho o ka ipu i komo mai ai, hoʻolei i nā papa i hoʻohana ʻole ʻia ma hope o 30 mau lā.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab a ma mua a i kou wā e mālama ai e nānā i ka pane o kou kino i trifluridine a me tipiracil.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

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