Midostaurin

Anter

• Ma mua o ka lawe ʻana i ka midostaurin,
• Hoʻokumu paha ʻo Midostaurin i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

Hoʻohana ʻia ʻo Midostaurin me nā lāʻau chemotherapy ʻē aʻe e mālama i kekahi ʻano o ka leukemia myeloid nui (AML; kahi ʻano maʻi ʻaʻai o nā hunaola keʻokeʻo). Hoʻohana ʻia ʻo Midostaurin i kekahi ʻano mastocytosis (kahi maʻi maʻi koko kahi e nui ai nā mast mast [kahi ʻano keokeo keʻokeʻo]). Aia ʻo Midostaurin i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o ka protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hōʻoki ʻana i ka mast a me nā hunaola maʻi ʻaʻai.

Hele mai ʻo Midostaurin ma ke ʻano he capsule e lawe ma ka waha. Lawe ʻia ia me ka meaʻai i ʻelua mau manawa o ka lā. Lawe i ka midostaurin ma nā manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono i ka midostaurin e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā capsule holoʻokoʻa; mai wehe a wāwahi paha iā lākou.

Inā luaʻi ʻoe ma hope o ka lawe ʻana i ka midostaurin, mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau o midostaurin a i ʻole e haʻi iā ʻoe e hoʻōki i ka lawe ʻana i ka midostaurin no kekahi manawa a i ʻole i ka wā o kāu mālama ʻana. Aia kēia i nā hopena ʻaoʻao āu e ʻike ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana. E hoʻomau i ka lawe ʻana i ka midostaurin ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ka midostaurin me ke kamaʻilio ʻole ʻana me kāu kauka.

E haʻi paha kāu kauka iā ʻoe e lawe i ka lāʻau e pale ai i ka pualu a me ka luaʻi ma mua o kēlā me kēia kau o ka midostaurin.

E noi i kāu kauka lāʻau a kauka paha no kahi kope o ka ʻike a ka mea hana no ka mea maʻi.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka midostaurin,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka midostaurin, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i nā capsule midostaurin. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, a me nā mea hoʻopihaʻai pono ʻole āu e lawe nei a hoʻolālā paha e lawe. E hoʻomaopopo pono e ʻōlelo i kekahi o kēia mau mea: boceprevir (ʻaʻole i loaʻa hou ma ka US; Victrelis); carbamazepine (Carbatrol, Equetro, Tegretol, a me nā mea ʻē aʻe); clarithromycin (Biaxin, i Prevpac); diltiazem (Cardizem, Cartia, Tiazac, nā mea ʻē aʻe); enzalutamide (Xtandi); idelalisib (Zydelig); itraconazole (Onmel, Sporanox); ketoconazole (Nizoral); nā lāʻau i hoʻohana ʻia e mālama ai i nā maʻi maʻi (HIV) e like me ka cobicistat (Tybost, ma Evotaz, ma Genvoya, ma Prezcobix, ma Stribild), elvitegravir (Vitekta), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir, ma Kaletra , ma Technivie, ma Viekira), saquinavir (Invirase) a me tipranavir (Aptivus); mitotane (Lysodren); nefazodone; phenytoin (Dilantin, Phenytek); posaconazole (Noxafil); rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater); troleandomycin (ʻaʻole loaʻa ma ka U.S.); a me voriconazole (Vfend). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Pili pū paha nā lāʻau ʻē aʻe he nui me ka midostaurin, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo ka wort ʻo St.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa paha i kahi puʻuwai kīnā ʻole, QT hoʻolōʻihi (kahi pilikia puʻuwai e hiki ai ke hōʻeha i ka puʻuwai maikaʻi ʻole, maʻule, a make koke paha), akemāmā, ake, a i ʻole nā ​​maʻi puʻupaʻa.
• e haʻi i kāu kauka inā hāpai ʻoe a i ʻole hoʻolālā e hāpai. Inā he wahine ʻoe, ʻaʻole pono ʻoe e hāpai i ka wā e lawe ana ʻoe i ka midostaurin a i ʻehā mau mahina ma hope o kāu hopena hope loa. Pono ʻoe e loaʻa i kahi hōʻike hāpai kino maikaʻi ʻole ma waena o 7 mau lā ma mua o kou hoʻomaka ʻana i ka midostaurin. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Inā he kāne ʻoe, pono ʻoe a me kāu pakanā wahine e hoʻohana i ka kaohi hānau i ka wā o kāu mālama ʻana a hoʻomau i ka hoʻohana ʻana i ka kaohi hānau no 4 mau mahina ma hope o kāu hopena hope loa. Inā hāpai ʻoe a ʻo kāu hoa paha i ka lawe ʻana i ka midostaurin, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Midostaurin i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū. ʻAʻole pono ʻoe e hānai i ka wā e lawe ana ʻoe i ka midostaurin a no 4 mau mahina ma hope o kāu hopena hope loa.
• pono ʻoe e ʻike i kēia lāʻau i hoʻemi ai i ka momona i nā kāne a me nā wahine.

E kamaʻilio me kāu kauka e pili ana i ka ʻai ʻana i ka huaʻōlau a me ka inu ʻana i ka wai momona a ke lawe nei ʻoe i kēia lāʻau.

Inā ʻaʻole haʻi kāu kauka iā ʻoe, e hoʻomau i kāu papaʻai maʻamau.

E haʻalele i ka lāʻau i haʻalele ʻia a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Midostaurin i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• ka luaʻi
• pāhoehoe
• ʻeha poʻo
• ihu ihu
• luhi
• nāwaliwali
• ʻūpā
• kōpaʻa
• hemorrhoids
• hoʻonui sweating
• ʻeha ka ʻōpū
• nā pā keʻokeʻo a i ʻole nā ​​ʻeha ma nā lehelehe a i ka waha a me ka ʻāʻī
• ka pehu o nā lima, ka wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
• kua, iwi, pili, lālā, a ʻeha ʻeha hoʻi
• paʻakikī e hiamoe a hiamoe paha

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• fiva, uha, ʻāʻī ʻeha, haʻalulu, a me nā ʻōuli ʻē aʻe o ka maʻi
• wikiwiki, kūlike ʻole, a kuʻi paha i ka puʻuwai puʻuwai
• pokole o ka hanu
• ʻeha ka umauma
• ʻōhinu
• pehu o nā lehelehe, alelo, a puʻu paha
• pilikia i ka hanu ʻana a i ʻole ke ale ʻana
• hives
• hūwī
• ʻūlili
• ʻūhū hou a i ʻole worsening paha
• ʻūhā
• luaʻi i ke koko a i ʻole ka luaʻi o nā mea e like me ke kahua kope
• kahe koko ʻole ʻana a palapū paha
• ʻāʻī a ʻeha paha i ka wā e urination

Hiki i ka Midostaurin ke kumu i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha paha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ka midostaurin.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Rydapt^®