Ceritinib

Anter

• Ma mua o ka lawe ceritinib,
• Hoʻokumu paha ʻo Ceritinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻĀLU MAKAHIKI kūikawā, e kāhea koke i kāu kauka:

Hoʻohana ʻia ʻo Ceritinib e mālama i kekahi ʻano maʻi ʻaʻai liʻiliʻi liʻiliʻi liʻiliʻi (NSCLC) i hoʻolaha ʻia i nā ʻāpana ʻē aʻe o ke kino. Aia ʻo Ceritinib i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o kahi protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hoʻolohi a hoʻopau paha i ka hoʻolaha ʻana o nā hunaola maʻi ʻaʻai.

Hele mai ʻo Ceritinib ma ke ʻano he capsule a me kahi papa e lawe ʻia e ka waha. Lawe mau ʻia me ka meaʻai hoʻokahi i ka lā. Lawe i ka ceritinib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. E lawe i ka ceritinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

Inā ʻoe e luaʻi ma hope o ka lawe ʻana i ka ceritinib, mai lawe i kahi lāʻau ʻē aʻe. E hoʻomau i kāu papa hana maʻamau.

Hiki i kāu kauka ke hōʻemi i kāu lāʻau o ceritinib, mālama iā ʻoe me nā lāʻau ʻē aʻe, a i ʻole e haʻi iā ʻoe e haʻalele i ka lawe ʻana i ka ceritinib no kahi manawa i kou wā e mālama ai. E pili kēia i ka maikaʻi o ka hana ʻana o ka lāʻau iā ʻoe a me nā hopena ʻē aʻe āu e ʻike ai. E haʻi pono i kāu kauka i kou ʻano i kou wā e mālama ai me ceritinib.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ceritinib,

• e haʻi i kāu kauka a me ka mea kauka lāʻau inā he maʻi ʻoe i ka ceritinib, nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o nā capsule ceritinib a i ʻole nā ​​papa. E noi i kāu kauka lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: amiodarone (Nexterone, Pacerone); anagrelide (Agrylin); anticoagulants ('blood thinners') e like me warfarin (Coumadin, Jantoven); beta blockers e like me atenolol (Tenormin), labetalol (Normodyne), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), propranolol (Inderal) a me sotalol (Betapace, Sorine, Sotylize); carbamazepine (Carbatrol, Epitol, Equetro, Tegretol, Teril); kekahi mau lāʻau no ka maʻi pale maʻi (HIV) a i ʻole loaʻa i ka maʻi maʻi maʻi maʻi (AIDS) e like me efavirenz (Sustiva, i Atripla), indinavir (Crixivan), nelfinavir (Viracept), nevirapine (Viramune), ritonavir (Norvir, ma Kaletra), a saquinavir (Hoʻokele); chloroquine; chlorpromazine; cilostazol; ciprofloxacin (Cipro); citalopram (Celexa); clarithromycin; clonidine (Catapres, Kapvay); Corticosteroids; cyclosporine (Gengraf, Neoral, Sandimmune); digoxin (Lanoxin); diltiazem (Cardizem, Dilacor, Tiazac); disopyramide (Norpace); dofetilide (Tikosyn); donepezil (Aricept); dronedarone (Multaq); escitalopram (Lexapro); fentanyl (Abstral, Actiq, Duragesic, Fentora, Subsys); flecainide (Tambocor); fluconazole (Diflucan); haloperidol (Haldol); ibutilide (Corvert); itraconazole (Onmel, Sporanox, Tolsura); ketoconazole; levofloxacin; methadone (Dolophine, Methadose); moxifloxacin (Avelox); nefazodone; ondansetron (Zuplenz, Zofran); pentamidine (Pentam); phenobarbital; phenytoin (Dilantin, Phenytek); pimozide (Orap); pioglitazone (Actos, ma Duetact, Oseni); procainamide; quinidine (i Nuedexta); rifabutin (Mycobutin); rifampin (Rifadin, Rimactane, ma Rifater); sildenafil (Revatio); sirolimus (Rapamune); tacrolimus (Astagraf, Prograf); thioridazine; vardenafil (Levitra, Staxyn); a me verapamil (Calan, Covera, Isoptin, Verelan). Nui paha nā lāʻau ʻē aʻe e launa pū me ceritinib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo keu ʻo St. John's Wort.
• e haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi diabetes a i ʻole ke kō i ke kō, kiʻekiʻe ʻole o ka puʻuwai, kahi puʻuwai puʻuwai ʻole, QT hoʻolōʻihi (kahi puʻuwai puʻuwai kūpono ʻole e hiki ai i ka nāwaliwali, nalowale o ka ʻike, hopu ʻana, a make koke paha), kahi pae haʻahaʻa. o ka potassium a i ʻole magnesium i loko o kou koko, pancreatitis (hoʻāla o ka pancreas), a i ʻole ka maʻi ate.
• e haʻi i kāu kauka inā hāpai ʻoe, a i ʻole hoʻolālā e hāpai. ʻAʻole pono ʻoe e hāpai i ka wā e lawe ana ʻoe i ceritinib. Pono ʻoe e loaʻa i kahi hōʻike hāpai ma mua o kou hoʻomaka ʻana i ka lāʻau, a pono ʻoe e hoʻohana i ka kaohi hānau e pale ai i ka hāpai ʻana i kāu wā lapaʻau a no 6 mau mahina ma hope o kāu hopena hope loa. Inā he kāne ʻoe me kāu hoa wahine e hāpai ana, pono ʻoe e hoʻohana i ka kaohi hānau e pale i ka hāpai ʻana i kou wā lapaʻau a no 3 mau mahina ma hope o kāu hopena hope loa. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Hiki paha iā Ceritinib ke hoʻopōʻino i kāu pēpē i hānau ʻole ʻia. Inā hāpai ʻoe a ʻo kāu hoa paha i ka wā o kāu mālama ʻana me ceritinib, e kāhea koke i kāu kauka.
• e haʻi i kāu kauka inā ʻoe e hānai umauma ana. ʻAʻole pono ʻoe e hānai i ka umauma ʻoiai ʻoe e lawe ana i ka ceritinib a no 2 mau pule ma hope o kāu hopena hope loa.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o ka niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ceritinib.
• pono ʻoe e ʻike e ʻike paha ʻoe i ka hyperglycemia (hoʻonui i kāu kō kō) ʻoiai ʻoe e lawe nei i kēia lāʻau. E haʻi koke i kāu kauka inā loaʻa iā ʻoe kekahi o nā ʻōuli aʻe ke lawe nei ʻoe i ka ceritinib: make wai loa, mimiki pinepine, pōloli loa, ʻike maka ʻole, ʻeha ka noʻonoʻo a noʻonoʻo paha, hanu e like me nā hua, a nāwaliwali paha.

Mai ʻai i ka hua waina a i ʻole inu i ka wai huaʻulu i ka wā e lawe ana i kēia lāʻau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā aia ma waena o 12 mau hola o kāu kau ma hope, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Ceritinib i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• nausea
• pāhoehoe
• ka luaʻi
• kōpaʻa
• ʻeha ka ʻōpū
• puʻuwai puʻuwai
• paʻakikī i ka ale ʻana
• nalo ʻai ʻole
• Kaumaha emi
• luhi
• hūwī
• ʻūlili
• nā hoʻololi i ka hihiʻo
• ʻami, iwi, lima hoʻi, a ʻeha ʻeha paha
• ʻeha poʻo

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻĀLU MAKAHIKI kūikawā, e kāhea koke i kāu kauka:

• ʻeha ma ka ʻaoʻao ʻākau i luna o ka ʻōpū
• ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
• mimi ʻeleʻele
• melemele o ka ʻili a me nā maka
• hoʻēmi ʻai
• nā ʻōuli like flu
• ʻūlili
• pokole o ka hanu
• ke kuni, ke anu, ka ʻāʻī, ka ʻū a me ka paʻa mau, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• ʻeha o ka umauma a hōʻoluʻolu ʻole paha
• nā hoʻololi i ka puʻuwai puʻuwai
• palpitations puʻuwai
• ʻūpā
• ʻālohilohi
• maule ana
• ʻeha mau e hoʻomaka i ka hema hema a i ʻole ka waena o ka ʻōpū akā hiki ke pālahalaha i ka hope
• ka hopu ʻana

Hoʻokumu paha ʻo Ceritinib i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a mamao aku mai ka mālamalama, ka wela a me ka momona o ka wela (ʻaʻole i loko o ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua lab e nānā i ka pane o kou kino i ceritinib. E kauoha pū kāu kauka i kahi hoʻokolohua lab ma mua o kou hoʻomaka ʻana i kāu lāʻau e ʻike inā hiki ke mālama ʻia i kou maʻi ʻaʻai me ceritinib.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Zykadia^®