Lomitapide

Anter

• Ma mua o ka lawe ʻana i ka lomitapide,
• Hoʻokumu paha ʻo Lomitapide i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e hoʻōki i ka lawe ʻana i ka lomitapide a kāhea koke aku i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.

Hoʻokumu paha ʻo Lomitapide i nā hōʻino nui i ke ake. E haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi akepau a i ʻole inā ua loaʻa mua ʻoe i nā pilikia o ke akepaʻa ke lawe ʻoe i nā lāʻau ʻē aʻe.E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka lomitapide. E haʻi i kāu kauka inā inu ʻoe i ka waiʻona. ʻO ka inu ʻana i ka waiʻona e hoʻonui paha i ka makaʻu e hoʻomohala ʻoe i nā pilikia o ke ake. Mai inu i hoʻokahi mea inu ʻona i kēlā me kēia lā ke lawe nei ʻoe i ka lomitapide. E haʻi i kāu kauka a me ka kauka inā ʻoe e lawe ana i ka acetaminophen (Tylenol, nā mea ʻē aʻe), amiodarone (Cordarone), doxycycline (Doryx, Vibramycin, a me nā mea ʻē aʻe), isotretinoin (Accutane), methotrexate (Rheumatrex), minocycline (Dynacin, Minocin), tamoxifen (Nol. ), a i ʻole tetracycline (Sumycin). Inā ʻoe e ʻike i kekahi o nā ʻōuli i lalo i kēlā me kēia manawa i kāu wā e lapaʻau ai, e hoʻōki i ka lawe ʻana i ka lomitapide a kāhea koke aku i kāu kauka: ka luhi nui loa, ka nele o ka ikaika, nāwaliwali, nausea a i ʻole ka luaʻi e ʻoi aku ana ka maikaʻi a ʻaʻole hoʻi e hele, ʻeha ma ka ʻaoʻao ʻākau kiʻekiʻe ʻāpana o ka ʻōpū, nalowale o ka makemake ʻole, melemele o ka ʻili a me nā maka, kuni, a me nā hōʻailona like flu. Pono paha kāu kauka e hoʻololi i ka lāʻau a oki paha a hoʻolohi paha i kāu lāʻau inā ʻike ʻoe i nā pilikia o ke ake.

ʻO kahi papahana i kapa ʻia ʻo Juxtapid REMS^® ua ʻae ʻia e ka Food and Drug Administration (FDA) ma muli o ka hiki ke hōʻino ʻia ke ake e pili ana i ka hoʻohana ʻana o lomitapide. Pono nā kānaka āpau i kuhikuhi ʻia i ka lomitapide e loaʻa kahi palapala lomitapide mai ke kauka i hoʻopaʻa inoa ʻia me Juxtapid REMS^®, a hoʻopiha ʻia ke kuhikuhi ma kahi kauka lāʻau i hoʻopaʻa inoa ʻia me Juxtapid REMS^® i mea e loaʻa ai kēia lāʻau.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua ma mua a i kou wā e mālama ai e nānā i ka pane o kou kino i ka lomitapide.

E hāʻawi aku kāu kauka a mea kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Ke alakaʻi alakaʻi) ke hoʻomaka ʻoe i ka lāʻau me lomitapide a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Hoʻohana ʻia ʻo Lomitapide me nā loli o ka papaʻai (kaohi ʻana o ke kōpaʻa a me ka lawe ʻana i ka momona) a me nā lāʻau lapaʻau ʻē aʻe e hōʻemi i ka nui o ka lipoprotein (LDL) kolokolo haʻahaʻa ('kolesterol maikaʻi'), ka huina kolesterol, a me nā mea momona ʻē aʻe i ke koko i ka poʻe. i loaʻa iā homozygous familial hypercholesterolemia (HoFH; kahi ʻano hoʻoilina kahi hiki ʻole ke hemo ʻia ka cholesterol mai ke kino maʻamau). ʻAʻole pono e hoʻohana ʻia ʻo Lomitapide e hoʻoliʻiliʻi i nā kiʻekiʻe o ka cholesterol i ka poʻe ʻaʻohe o lākou HoFH. Aia ʻo Lomitapide i loko o ka papa o nā lāʻau i kapa ʻia ʻo nā kolokoli hoʻohaʻahaʻa kolesterol. Hana ia ma ka hoʻolohi ʻana i ka hana ʻana o ka kōkōkō i loko o ke kino e hōʻemi i ka nui o ka kolesterol e kūkulu ʻia ma nā paia o nā aʻa a ālai i ke kahe o ke koko i ka puʻuwai, lolo, a me nā ʻāpana ʻē aʻe o ke kino.

ʻO ka hōʻuluʻulu ʻana o ka cholesterol a me nā momona ma nā paia o kou aʻa (kahi hana i ʻike ʻia ʻo atherosclerosis) e hoʻemi ana i ke kahe o ke koko a, no laila, hāʻawi ka oxygen i kou puʻuwai, lolo, a me nā ʻāpana ʻē aʻe o kou kino Hiki ke kōkua i ka hoʻohaʻahaʻa ʻana i ke kiʻekiʻe o kou koko a me nā momona ke pale aku i nā maʻi puʻuwai, angina (ʻeha o ka umauma), nā hahau, a me nā hōʻeha puʻuwai.

Hele mai ʻo Lomitapide ma ke ʻano he capsule e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā. Lomitapide e lawe ʻia me ka ʻole o ka meaʻai ma ka ʻōpū hakahaka, ma ka liʻiliʻi he 2 mau hola ma hope o kāu ʻaina ahiahi. Inu i kahi kīʻaha piha o ka wai me kēlā me kēia mahele o lomitapide.

Lawe i ka lomitapide ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pololei i ka lomitapide e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā capsule holoʻokoʻa; mai hoʻokaʻawale, nau aʻe, hoʻonā a wāwahi paha iā lākou.

Pono ʻoe e lawe i kahi huaora i ka wā o kāu mālama ʻana me ka lomitapide E mālama pono i nā ʻōlelo aʻoaʻo a kou kauka i hana pono ai.

E hoʻomau i ka lawe ʻana i ka lomitapide ʻoiai inā maikaʻi ʻoe. Mai hōʻoki i ka lawe ʻana i ka lomitapide me ke kamaʻilio ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i ka lomitapide,

• e haʻi i kāu kauka a me kāu kauka lāʻau inā he maʻi ʻoe i ka lomitapide, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o nā capsule lomitapide. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka inā lawe ʻoe i nā lāʻau antifungal e like me fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), a me voriconazole (Vfend); boceprevir (Victrelis); aprepitant (Emend); ciprofloxacin (Cipro); clarithromycin (Biaxin); crizotinib (Xalkori); diltiazem (Cardizem, Dilacor, Tiazac); erythromycin (E.E.S., E-Mycin, Erythrocin); Nā mea kūpale protease HIV e like me amprenavir (Agenerase), atazanavir (Reyataz), darunavir (Prezista), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir (i Kaletra), nelfinavir (Viracept), saquinavir (Invirase (Norir), ritonav i Kaletra), ritonavir a me tipranavir (Aptivus), a me teleprevir (Incivek); imatinib (Gleevec); nefazodone; telithromycin (Ketek); a me verapamil (Calan, Covera, Isoptin, Verelan). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka lomitapide inā ʻoe e lawe i hoʻokahi a ʻoi paha o kēia mau lāʻau.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E ʻōlelo pono i nā lāʻau i helu ʻia i ka ʻARlelo Aʻo IMPORTANT a me kekahi o kēia mau mea: aliskiren (Tekturna); alprazolam (Xanax); ambrisentan (Letairis); amiodarone (Cordarone, Pacerone); amlodipine (Norvasc, ma Caduet); bicalutamide (Casodex); cilostazol (Pletal); kekahi mau lāʻau lapaʻau waha no ka maʻi diabetes e like me saxagliptin (Onglyza ma Kombiglyze) a me sitagliptin (Januvia, i Janumet); cimetidine (Tagament); colchisin (Colcrys); dabigatran (Pradaxa); digoxin (Lanoxin); everolimus (Afinitor, Zortress); fexofenadine (Allegra); fluoxetine (Prozac); fluvoxamine (Luvox); isoniazid (INH, Nydrazid); lapatinib (Tykerb); maraviroc (Selzentry); nā lāʻau e kāohi i ka ʻōnaehana pale e like me cyclosporine (Gengraf, Neoral, Sandimmune), sirolimus (Rapamune) a me tacrolimus (Prograf); nilotinib (Tasigna); nā pale pale waha (nā pā kaohi hānau); nā lāʻau hoʻohaʻahaʻa kolesterol e like me atorvastatin (Lipitor, ma Caduet, ma Liptruzet), lovastatin (Mevacor), a me simvastatin (Zocor, ma Simcor, ma Vytorin); pazopanib (Votrient); ranitidine (Zantac); ranolazine (Ranexa); ticagrelor (Brilinta); tolvaptan (Samsca); topotecan (Hycamtin); warfarin (Coumadin); a me zileuton (Zyflo). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me ka lomitapide, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, keu hoʻi ka ginkgo a i ʻole ke goldenseal.
• inā ʻoe e lawe nei i ka cholestyramine (Questran), colesevelam (WellChol), a i ʻole colestipol (Colestid), e lawe iā 4 mau hola ma mua a i ʻole 4 mau hola ma hope o lomitapide.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa ʻole ka hoʻomanawanui ʻole galactose a i ʻole glucose-galactose malabsorption (nā ʻano hoʻoilina kahi hiki ʻole i ke kino ke hoʻomanawanui i ka lactose), ka hoʻomau ʻana o ka ʻōpū a me nā ʻōpū o ka ʻōpū, a i ʻole pancreas a i ʻole nā ​​maʻi pākī.
• E haʻi i kāu kauka inā hāpai ʻoe a hoʻolālā paha e hāpai. Inā he wahine ʻoe i hiki ke hāpai, pono ʻoe e lawe i kahi hōʻike hāpai keiki ma mua o kou hoʻomaka ʻana e lawe i ka lomitapide. Inā hiki iā ʻoe ke hāpai, pono ʻoe e hoʻohana i ka kaohi hānau pono i ka lawe ʻana i ka lomitapide. E kamaʻilio me kāu kauka e pili ana i nā hana kaohi hānau e holo pono nāu. Inā hāpai ʻoe i ka lawe ʻana i ka lomitapide, kāohi i ka lawe ʻana i ka lāʻau a kāhea koke i kāu kauka. Hiki i ka Lomitapide ke hōʻeha i ka fetus.
• e haʻi i kāu kauka inā ʻoe e hānai umauma ana. ʻAʻole pono ʻoe e hānai i ka umauma ʻoiai ʻoe e lawe nei i ka lomitapide.

Mai ʻai i ka hua waina a i ʻole inu i ka wai huaʻulu i ka wā e lawe ana i kēia lāʻau.

E haʻi aku kāu kauka iā ʻoe e ʻai i ka papaʻai momona momona. ʻO ka ʻai ʻana i kahi papaʻai momona momona hiki ke hoʻohaʻahaʻa i ka manawa e loaʻa iā ʻoe nā pilikia o ka ʻōpū e like me ka nausea, ka luaʻi, ka ʻōpū huhū, a me ka palahī ʻoiai ʻoe e lawe nei i ka lomitapide. E hāhai pono i nā ʻōlelo papaʻai āpau i hana ʻia e kāu kauka a i ʻole kauka hānai.

E haʻalele i ka lāʻau i haʻalele ʻia a hoʻomau i kāu papa hana hana maʻamau i ka lā aʻe. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hoʻokumu paha ʻo Lomitapide i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• pāhoehoe
• nausea
• ka luaʻi
• ʻeha ka ʻōpū
• kōpaʻa
• ʻōhūhū
• ʻenekini
• hoʻohuhū ʻōpū
• Kaumaha emi
• ʻeha poʻo
• ʻūpā
• eha ka 'ā'ī
• ihu ihope
• ʻeha kua

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e hoʻōki i ka lawe ʻana i ka lomitapide a kāhea koke aku i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.

• ʻōpū nui loa
• ʻālohilohi
• hoʻemi i ka puka mimi

Hoʻokumu paha ʻo Lomitapide i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Juxtapid^®