Mifepristone (Korlym)

Anter

• Ma mua o ka lawe ʻana i mifepristone,
• Hiki i ka Mifepristone ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

No nā maʻi wahine:

Mai lawe iā mifepristone inā hāpai ʻoe a hoʻolālā paha e hāpai. Hiki i ka Mifepristone ke kumu o ka nalo ʻana o ka hāpai keiki. Pono ʻoe e hōʻoia i kahi hāpai hāpai maikaʻi ʻole ma mua o ka hoʻomaka ʻana o ka mālama ʻana me mifepristone a ma mua o ka hoʻomaka ʻana o ka lāʻau ʻana inā kū ʻoe i ka lawe ʻana ma mua o 14 mau lā. Inā hiki iā ʻoe ke hāpai, pono ʻoe e hōʻalo i ka hāpai ʻana i ka wā o kāu mālama ʻana me mifepristone. Pono ʻoe e hoʻohana i nā ʻano ʻoluʻolu o ka kaohi hānau i kāu wā e mālama ai a no ka liʻiliʻi o 1 mahina ma hope o ka pau ʻana o kāu lāʻau. E haʻi aku kāu kauka iā ʻoe i ke ʻano o ka kaohi hānau e ʻae ʻia. Inā manaʻo ʻoe he hāpai ʻoe, ua haʻo ʻoe i kahi manawa menstrual, a i ʻole moe kolohe ʻoe me ka hoʻohana ʻole ʻana i ka kaohi hānau ʻoiai e lawe ana i ka mifepristone a i ʻole ma loko o 1 mahina ma hope o kāu lapaʻau ʻana, e kāhea koke i kāu kauka.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha paha kāu kauka i kekahi mau hoʻokolohua e nānā ai i ka pane o kou kino iā mifepristone.

E hāʻawi aku kāu kauka a mea kauka paha iā ʻoe i ka palapala ʻike hoʻomanawanui o ka mea hana (Ke Alakaʻi Medication) ke hoʻomaka ʻoe i ka lāʻau me mifepristone a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

E kamaʻilio me kāu kauka e pili ana i ka makaʻu o ka lawe ʻana i ka mifepristone.

Hoʻohana ʻia ʻo Mifepristone (Korlym) e mālama i ka hyperglycemia (ke kō kiʻekiʻe o ke kō) i ka poʻe me kekahi ʻano o ka maʻi ʻo Cushing kahi e hana ai ke kino i ka nui o ka cortisol (kahi hōmona) a ua kūleʻa ʻole i ka ʻoki ʻana a i ʻole hiki ʻole ke ʻoki ʻia e mālama ai i kēia ʻano. Aia ʻo Mifepristone i loko o ka papa o nā lāʻau i kapa ʻia he blockerol receptor blockers. Hana ia ma ka pale ʻana i ka hana o cortisol.

Loaʻa ʻo Mifepristone ma ke ʻano he huahana ʻē aʻe (Mifeprex) i hoʻohana hoʻokahi ʻia a i ʻole me ka hoʻohui ʻia me kekahi lāʻau e hoʻopau ai i ka hāpai mua. Hāʻawi wale kēia monograp i ka ʻike e pili ana i ka mifepristone (Korlym) i hoʻohana ʻia e kaohi i ka hyperglycemia i ka poʻe me kekahi ʻano o ka maʻi o Cushing. Inā ʻoe e hoʻohana ana i ka mifepristone e hoʻopau ai i kahi hāpai ʻana, e heluhelu i ka monograph i kapa ʻia ʻo mifepristone (Mifeprex), i kākau ʻia e pili ana i kēia huahana.

Hele mai ʻo Mifepristone ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā me kahi pāʻina. Lawe i ka mifepristone ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe i mifepristone e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou. E haʻi i kāu kauka a kauka paha inā ʻaʻole hiki iā ʻoe ke ale i nā papa āpau.

E hoʻomaka kāu kauka iā ʻoe ma kahi haʻahaʻa o ka mifepristone a hoʻonui iki i kāu lāʻau, ʻaʻole ʻoi aku ka pinepine ma mua o hoʻokahi manawa i kēlā me kēia 2 a 4 mau pule. Inā kū ʻoe i ka lawe ʻana i ka mifepristone, e kāhea i kāu kauka. Pono paha kāu kauka e hoʻomaka hou iā ʻoe ma ka hopena haʻahaʻa o ka mifepristone a hoʻonui iki i kāu lāʻau.

Hiki i ka Mifepristone ke kāohi i kou kūlana akā ʻaʻole ia e hoʻōla iā ia. He 6 mau pule paha a ʻoi paha ka lōʻihi ma mua o kou ʻike ʻana i ka pono piha o ka mifepristone. E hoʻomau i ka lawe i ka mifepristone ʻoiai inā maikaʻi ʻoe.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ʻana i mifepristone,

• e haʻi i kāu kauka inā ʻaʻa ʻoe i ka mifepristone, i nā lāʻau ʻē aʻe, a i ʻole kekahi o nā mea hana i loko o ka papa nifepristone. E noi i kāu kauka lāʻau a nānā paha i ka ʻike hoʻomanawanui o ka mea hana no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka inā lawe ʻoe i kekahi o nā lāʻau i hope aʻe a i ʻole lawe ʻia i nā pule ʻelua i hala: corticosteroids e like me betamethasone (Celestone), budesonide (Entocort), cortisone (Cortone), dexamethasone (Decadron, Dexpak, Dexasone, a me nā mea ʻē aʻe) , fludrocortisone (Floriner), hydrocortisone (Cortef, Hydrocortone), methylprednisolone (Medrol, Meprolone, a me nā mea ʻē aʻe), prednisolone (Prelone, nā mea ʻē aʻe), prednisone (Deltasone, Meticorten, Sterapred, a me nā mea ʻē aʻe), a me triamcinolone (Aristocort, Azmacort); nā lāʻau e kāohi i ka ʻōnaehana pale e like me cyclosporine (Neoral, Sandimmune), sirolimus (Rapamune), a me tacrolimus (Prograf); dihydroergotamine (D.H.E. 45, Migranal); ergotamine (Ergomar, ma Cafergot, ma Migergot); fentanyl (Duragesic); lovastatin (Mevacor); pimozide (Orap); quinidine (Quinidex); a me simvastatin (Zocor). E haʻi paha kāu kauka iā ʻoe ʻaʻole e lawe i ka mifepristone inā ʻoe e lawe i hoʻokahi a ʻoi paha o kēia mau lāʻau.
• e haʻi i kāu kauka a me ka mea lapaʻau i nā lāʻau lapaʻau, nā huaora, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a i ʻole lawe ʻia i nā pule ʻelua i hala. E haʻi pono i kekahi o kēia mau mea: anticoagulants ('nā mea lahilahi o ke koko') e like me warfarin (Coumadin); nā antifungals e like me itraconazole (Sporanox), ketoconazole (Nizoral), posaconazole (Noxafil), a i ʻole voriconazole (Vfend); aspirin a me nā lāʻau anti-inflammatory nonsteroidal (NSAIDs) e like me ibuprofen (Advil, Motrin) a me naproxen (Aleve, Naprosyn); bupropion (Wellbutrin); ciprofloxacin (Cipro); clarithromycin (Biaxin); konivaptan (Vaprisol); diltiazem (Cardizem); erythromycin (E.E.S., E-Mycin, Erythrocin); fluvastatin (Lescol); nā pale hormonal e like me nā lāʻau kaohi hānau, nā implants, nā palaki, nā apo, a i ʻole nā ​​injection nā lāʻau no ka maʻi hepatitis C e like me boceprevir (Victrelis) a me telaprevir (Incivek); nā lāʻau no ka HIV a me ka maʻi AIDS e like me amprenavir (Agenerase), atazanavir (Reyataz), efavirenz (Sustiva), fosamprenavir (Lexiva), indinavir (Crixivan), lopinavir a me ritonavir hoʻohui (Kaletra), nelfinavir (Viracept), ritonavir (Norvir) a me ka saquinavir (Fortovase, Invirase); nā lāʻau no ka hopu ʻana e like me ka carbamazepine (Tegretol), phenobarbital (Luminal, Solfoton), phenytoin (Dilantin); nā lāʻau no ka tuberculosis e like me rifabutin (Mycobutin), rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater) a me rifapentine (Priftin); nefazodone (Serzone); repaglinide (Prandin); telithromycin (Ketek); a me ka verapamil (Calan, Isoptin, nā mea ʻē aʻe). Nui paha nā lāʻau ʻē aʻe e launa pū paha me ka mifepristone, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa. Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao.
• e haʻi i kāu kauka i nā huahana lāʻau āu e lawe nei, ʻo keu ʻo St. John's Wort.
• e haʻi i kāu kauka inā loaʻa iā ʻoe kahi transplant organ a i ʻole inā he maʻi thyroid paha kāu. Inā he wahine ʻoe a ʻaʻohe ou ʻoki e wehe i kou kōpū, e haʻi i kāu kauka inā loaʻa a i ʻole loaʻa ʻole ka wehewehe ʻana i ke kahe o ka maʻi puʻupuʻu, endometrial hyperplasia (overgrowth of the lining of the uterus), or endometrial cancer (cancer of the lining of kou kōpū). E haʻi paha kāu kauka iā ʻoe mai lawe i ka mifepristone.
• e haʻi i kāu kauka inā loaʻa ʻole a i ʻole loaʻa paha ʻoe i ka puʻuwai ʻole, kahi wā QT hoʻolōʻihi (kahi pilikia puʻuwai laha ʻole e hiki ai ke hōʻeha i ka puʻuwai ʻole, maʻule, a make koke paha), potassium haʻahaʻa i loko o kou koko, lawa ʻole adrenal (ke ʻano kahi o nā adrenal glands. mai hana lawa i kekahi mau hormona e pono ai no nā hana koʻikoʻi o ke kino), kahi maʻi koko, a me ke ake, nā konā, a me nā maʻi puʻuwai.
• e haʻi i kāu kauka inā ʻoe e hānai umauma ana.

Mai ʻai i ka hua waina a i ʻole inu i ka wai huaʻikuʻi ke lawe nei ʻoe i kēia lāʻau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

Hiki i ka Mifepristone ke hana i nā hopena ʻaoʻao. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• ʻeha poʻo
• ka luaʻi
• waha maloo
• pāhoehoe
• kōpaʻa
• ʻeha hui a ʻeha ʻeha paha
• ka pehu o nā lima, ka wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo
• hūwī
• ʻūlili

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke i kāu kauka a i ʻole e kiʻi i ka lāʻau olakino olakino.

• nausea
• nalo ʻai ʻole
• dizziness a i ʻole ʻālohilohi
• luhi ʻole a nawaliwali paha
• hopohopo a huhū paha
• haʻalulu
• ka houʻu ʻana
• nāwaliwali o ka mākala, ʻeha, a i ʻole nā ​​ʻūlū
• wikiwiki, kūlike ʻole, a kuʻi paha i nā puʻuwai puʻuwai
• kahe ʻole o ke kahe o ke kolo
• pokole o ka hanu

Hoʻokumu paha ʻo Mifepristone i nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Ma mua o ka loaʻa ʻana o kahi hoʻokolohua hoʻokolohua, e haʻi i kāu kauka a me nā limahana o ke keʻena hoʻokolohua e lawe nei ʻoe i ka mifepristone.

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• ʻO Korlym^®