Ponatinib

Anter

• Ma mua o ka lawe ponatinib,
• ʻO Ponatinib paha ke kumu o nā hopena. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:
• Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e hoʻōki i ka lawe ʻana i ka ponatinib a kāhea koke aku i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.
• Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

Hiki paha i ka Ponatinib ke hana i ke koko a weliweli paha i kou mau wāwae a i ʻole nā ​​akemāmā, nā puʻuwai puʻuwai, a me nā hahau. E haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa kahi kōkō koko i kou mau māmā a mau wāwae paha; he hahau ʻana; ke koko kiʻekiʻe; hyperlipidemia (kiʻekiʻe o ke kolesterol i loko o kou koko); kahi puʻuwai lohi, wikiwiki, a i ʻole kaulike ʻole; maʻi maʻi ākea peripheral (hoʻoliʻiliʻi o nā kīʻaha koko i nā wāwae, nā wāwae, a i ʻole nā ​​lima e hoʻoulu ai i ka helu, ʻeha, a anuanu hoʻi i kēlā ʻāpana o ke kino); he puʻuwai puʻuwai; aiʻole maʻi puʻuwai. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: ʻeha o ka umauma; pokole o ka hanu; poniuniu a maʻule paha; huikau paha a pilikia paha e ʻōlelo a hoʻomaopopo paha; ʻōlohelohe ʻole a nawaliwali paha o ka maka, ka lima a i ʻole ka wāwae ma kekahi ʻaoʻao o ke kino; ʻeha poʻo poʻo loa; ʻeha ka wāwae, ka lima, ke kua, ka ʻāʻī, a me ka ʻāʻī; manaʻo o ka mahanahana i ka wāwae lalo; aiʻole ka pehu ʻana o nā wāwae, nā kuʻekuʻe wāwae, a me nā wāwae lalo.

Hiki i ka Ponatinib ke hana i nā puʻuwai koʻikoʻi a i ʻole hoʻoweliweli ola (ke ʻano i hiki ʻole i ka puʻuwai ke pauma i ke koko i nā ʻāpana ʻē aʻe o ke kino) a me nā arrhythmia (nā puʻuwai puʻuwai ʻokoʻa). E haʻi i kāu kauka inā loaʻa a loaʻa paha iā ʻoe nā pilikia puʻuwai, e like me ka puʻuwai puʻuwai, hoʻolōʻihi QT (kahi puʻuwai puʻuwai kūpono ʻole e hiki ai i ka nāwaliwali, nalowale o ka ʻike, hopu ʻana, a make koke paha); a i ʻole ke kuʻi puʻuwai, wikiwiki, a i ʻole kūleʻa. Inā ʻike ʻoe i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: ka pōkole o ka hanu; ʻeha ka umauma; wikiwiki, kūlike ʻole, a i ʻole kuʻi ka puʻuwai puʻuwai; ʻūpā; a maule paha.

ʻO Ponatinib paha ke kumu o ka hōʻeha koʻikoʻi a ola paha i ke ake. E haʻi i kāu kauka inā loaʻa a loaʻa paha ʻoe i ka maʻi ate a i ʻole nā ​​pilikia me kou ake. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli, e kāhea koke aku i kāu kauka: ʻili, maka melemele a i ʻole ʻili, mimi ʻeleʻele, a i ʻole ʻeha a hōʻoluʻolu ʻole paha ma ka ʻaoʻao ʻōpū o luna pono.

E mālama i nā manawa a pau me kāu kauka a me ka hale hana. E kauoha kāu kauka i kekahi mau hoʻokolohua ma mua o kou hoʻomaka a i kou wā o ka mālama ʻana e nānā i ka pane o kou kino iā ponatinib.

E hāʻawi aku kāu kauka a kauka paha iā ʻoe i ka ʻikepili ʻike hoʻomanawanui o ka mea hana (Ke alakaʻi alakaʻi) ke hoʻomaka ʻoe i ka lāʻau me ponatinib a i kēlā me kēia manawa e hoʻopiha hou i kāu kauka. E heluhelu pono i ka ʻike a nīnau i kāu kauka a kauka paha inā he nīnau kāu. Hiki iā ʻoe ke kipa aku i ka pūnaewele ʻo Food and Drug Administration (FDA) (http://www.fda.gov/Drugs/DrugSafety/ucm085729.htm) a i ʻole pūnaewele o ka mea hana e kiʻi i ka Medication Guide.

Hoʻohana ʻia ʻo Ponatinib e mālama i kekahi mau ʻano like ʻole o ka myeloid leukemia (CML; kahi ʻano maʻi ʻaʻai o nā hunaola keʻokeʻo), e like me ka mālama ʻana i ka poʻe hiki ʻole ke loaʻa pono hou mai nā lāʻau ʻē aʻe no CML a i ʻole hiki ʻole ke lawe i kēia mau lāʻau no ka hopena o ka hopena. Hoʻohana ʻia ʻo Ponatinib e mālama i kekahi ʻano o ka leukemia lymphoblastic huikau (ALL; kahi ʻano maʻi ʻaʻai o nā hunaola keʻokeʻo) i ka poʻe i hiki ʻole ke pōmaikaʻi hou ʻia mai nā lāʻau ʻē aʻe no ka leukemia a i ʻole hiki ʻole ke lawe i kēia mau lāʻau no ka hopena. Aia ʻo Ponatinib i kahi papa o nā lāʻau i kapa ʻia nā kinase inhibitors. Hana ia ma ke kāpae ʻana i ka hana o kahi protein pono ʻole e hōʻailona ai i nā hunaola maʻi ʻaʻai e hoʻonui. Kōkua kēia i ka hōʻoki ʻana i nā hunaola maʻi ʻaʻai.

Hele mai ʻo Ponatinib ma ke ʻano he papa e lawe ma ka waha. Lawe ʻia ia i hoʻokahi manawa i ka lā me ka ʻai ʻole. Lawe iā ponatinib ma kahi o ka manawa like i kēlā me kēia lā. E hāhai pono i nā ʻōkuhi i kāu lepili kuhikuhi, a nīnau i kāu kauka a kauka paha e wehewehe i kahi ʻāpana āu i maopopo ʻole ai. Lawe pono iā ponatinib e like me ke kuhikuhi. Mai lawe i ka mea ʻoi aku a liʻiliʻi paha o ia mea a lawe pinepine iā ia ma mua o ka mea i kauoha ʻia e kāu kauka.

E ale i nā papa holoʻokoʻa; mai hoʻokaʻawale, a nau aku, a hoka ʻole iā lākou.

Pono paha kāu kauka e hoʻolohi i kāu lāʻau, hoʻoponopono i kāu lāʻau, a i ʻole hoʻokū mau i kāu mālama ʻana o ponatinib ke kaukaʻi ʻia i kāu pane i ka lāʻau a me nā hopena ʻē aʻe āu e ʻike ai. E kamaʻilio me kāu kauka e pili ana i kou ʻano i kāu mālama ʻana. E hoʻomau i ka lawe ʻana i ponatinib inā ʻoe e ʻoluʻolu. Mai hōʻoki i ka lawe ʻana i ka ponatinib me ke kamaʻilio ʻole ʻana me kāu kauka.

Kau ʻia kēia lāʻau no nā hoʻohana ʻē aʻe; e noi i kāu kauka a kauka paha no ka ʻike hou aku.

Ma mua o ka lawe ponatinib,

• e haʻi i kāu kauka a me ka kauka inā he maʻi ʻoe i ka ponatinib, nā lāʻau ʻē aʻe, lactose, a i ʻole kekahi o nā mea hana i loko o nā papa ponatinib. E noi i kāu kauka lāʻau a nānā i ke alakaʻi lāʻau no kahi papa inoa o nā mea hoʻohui.
• e haʻi i kāu kauka a me ka mea kauka lāʻau i nā lāʻau lapaʻau, nā wikamina, nā mea hoʻopihapiha, a me nā huahana lāʻau āu e lawe nei a hoʻolālā paha e lawe. E haʻi pono i kekahi o kēia mau mea: ketoconazole (Nizoral); nā lāʻau e hoʻemi i ka waikawa ʻōpū, e like me lansoprazole (Prevacid); a me rifampin (Rifadin, Rimactane, ma Rifamate, ma Rifater). Pono paha kāu kauka e hoʻololi i nā kaha o kāu mau lāʻau a nānā pono iā ʻoe no nā hopena ʻaoʻao. Nui paha nā lāʻau ʻē aʻe e launa pū paha me ponatinib, no laila e ʻike pono i kāu kauka e pili ana i nā lāʻau a pau āu e lawe nei, a ʻo nā mea ʻaʻole i ʻike ʻia ma kēia papa inoa.
• e haʻi i kāu kauka inā loaʻa iā ʻoe a i ʻole loaʻa i kahi kahe koko; mimikō; pancreatitis (hāhā o ka pancreas, he gland ma hope o ka ʻōpū e hoʻopuka i nā mea e kōkua ai me ka digestion); aiʻole inā he lactose intolerant ʻoe (hiki ʻole ke ʻeli i nā huahana waiū). Eia kekahi, e haʻi i kāu kauka inā inu ʻoe a ua inu paha i ka nui o ka waiʻona.
• pono ʻoe e ʻike i ka hoʻihoʻi ʻana o ponatinib i ka momona i nā wahine. Eia nō naʻe, ʻaʻole pono ʻoe e kuhi ʻaʻole hiki iā ʻoe a i ʻole kāu pakanā ke hāpai. E haʻi i kāu kauka inā hāpai ʻoe a hoʻolālā paha e hāpai. Inā he wahine ʻoe, pono ʻoe e lawe i kahi hōʻike hāpai keiki ma mua o kou hoʻomaka ʻana i ka lāʻau. Pono ʻoe e hoʻohana i ka kaohi hānau e pale i ka hāpai ʻana i ka wā o kāu mālama ʻana me ponatinib a no 3 mau pule ma hope o kou hōʻoki ʻana i ka lawe ʻana i ka lāʻau. E kamaʻilio me kāu kauka e pili ana i nā ʻano o ka kaohi hānau e holo pono nāu. Inā hāpai ʻoe i ka lawe ʻana i ponatinib, e kāhea koke i kāu kauka. Hoʻopilikia paha ʻo Ponatinib i ka fetus.
• e haʻi i kāu kauka inā e hānai ana ʻoe i ka waiū a i ʻole hoʻolālā e hānai. ʻAʻole pono ʻoe e hānai i ka wā e lawe ana i ponatinib a no 6 mau lā ma hope o kāu hopena hope loa.
• inā ke ʻoki nei ʻoe, e like me ke kaha ʻana o nā niho, e haʻi i ke kauka a i ʻole kauka niho paha e lawe ana ʻoe i ponatinib. Inā hoʻonohonoho ʻia ʻoe e hana ʻia i kahi ʻoki, e haʻi aku kāu kauka iā ʻoe e haʻalele i ka lawe ʻana i ka ponatinib ma kahi o 7 mau lā ma mua o ke ʻoki a me ke kaʻina hana. E haʻi aku kāu kauka iā ʻoe i ka manawa e hoʻomaka ai e lawe hou i ponatinib ma hope o kāu ʻoki ʻana.
• pono ʻoe e ʻike e hoʻonui paha kou kahe koko i kou wā o ka mālama ʻana me ponatinib. E nānā paha kāu kauka i kou kaomi koko i kou wā e lapaʻau ai.

Mai ʻai i ka nui o ka huaʻulu a inu paha i ka wai huaʻikuʻi i ka wā e lawe ana i kēia lāʻau.

E lawe i ka lāʻau i hala i kou wā e hoʻomanaʻo ai. Eia nō naʻe, inā kokoke i ka manawa no ka mahele hope aʻe, e lele i ka lāʻau i hala a hoʻomau i kāu papa hana maʻamau. Mai lawe i kahi lāʻau pālua e pani no kahi mea i hala.

ʻO Ponatinib paha ke kumu o nā hopena. E haʻi i kāu kauka inā koʻikoʻi kekahi o kēia mau ʻōuli a mai hele aku paha:

• hūwī
• ʻili maloʻo
• pāhoehoe
• kōpaʻa
• poho lauoho
• nā pā keʻokeʻo a i ʻole nā ​​ʻeha ma nā lehelehe a i ka waha a me ka ʻāʻī
• nalo ʻai ʻole
• Kaumaha emi
• ʻūhā
• paʻakikī e hiamoe a hiamoe paha
• kua, iwi, pili, lālā, a ʻeha ʻeha hoʻi

Hiki i kekahi o nā hopena ʻaoʻao ke koʻikoʻi. Inā ʻoe e ʻike i kekahi o kēia mau ʻōuli a i ʻole nā ​​mea i helu ʻia i ka ʻARlelo Aʻo IMPORTANT, e hoʻōki i ka lawe ʻana i ka ponatinib a kāhea koke aku i kāu kauka a i ʻole e kiʻi i nā lāʻau lapaʻau pilikia.

• ʻāpā ʻaʻano ʻole a hoʻokahe koko paha
• koko a ʻeleʻele paha, noho aliʻi
• koko i ka mimi
• luaʻi koko
• he kahe maʻamau o ke kahe a ʻoi aku ka ʻoi aku o ke kaumaha ma mua o ke kahe maʻamau
• ka luaʻi e like me nā pā kope
• kahe pinepine ka ihu
• kahe ana ke koko
• mau maka maloʻo, ʻulaʻula, ʻeha, a hoʻonāukiuki paha
• ʻike i ka mālamalama
• ʻike hihi, floats, ʻike lua, a i ʻole nā ​​loli ʻike hou ʻē aʻe
• nā palapū hoola ʻole
• fiva, ʻeha ka ʻāʻī, haʻalulu, a i ʻole nā ​​hōʻailona ʻē aʻe o ka maʻi
• nā hoʻololi i ka ʻono; nāwaliwali o nā mākala; hāʻule nā ​​lihilihi a i ʻole ʻāpana o ka maka; ʻūlū, puhi, ʻeha, a i ʻole nalo ʻana o ka manaʻo i nā lima a me nā wāwae
• ʻeha poʻo, hopu ʻia, huikau, noʻonoʻo i nā pilikia, a i ʻole nā ​​loli a i ʻole ka nalo ʻana o ka ʻike
• hoʻemi urination
• ka luhi nui a nawaliwali paha
• loaʻa kaupaona
• ka pehu ʻana o kou alo, lima, wāwae, kuʻekuʻe wāwae, a i ʻole nā ​​wāwae lalo
• ʻeha, pehu, a palupalu paha i loko o ka ʻōpū (ʻōpū ʻōpū)
• nausea
• ka luaʻi
• ʻeha mau e hoʻomaka i ka wahi o ka ʻōpū akā e pālahalaha paha i ka hope

ʻO Ponatinib paha ke kumu o nā hopena ʻē aʻe. Kāhea i kāu kauka inā he pilikia ʻokoʻa kāu i ka lawe ʻana i kēia lāʻau.

Inā ʻoe e ʻike i kahi hopena koʻikoʻi, e hoʻouna ʻoe a i ʻole kāu kauka i kahi hōʻike i ka papahana hōʻike ʻino a MedWatch Adverse Event Food (FDA) ma ka pūnaewele (http://www.fda.gov/Safety/MedWatch) a i ʻole kelepona. 1-800-332-1088).

E mālama i kēia lāʻau i loko o ka pahu i komo ai, pani paʻa ʻia, a ʻaʻole hiki i nā kamaliʻi. E mālama iā ia i ka mahana wela o ka lumi a ma kahi o ka wela a me ka momona (ʻaʻole i ka lua.

He mea nui e mālama i nā lāʻau āpau mai ka maka a hiki i nā keiki e like me nā ipu (e like me nā minder pill i kēlā me kēia pule a me nā mea no nā kulu maka, nā kalima, nā pākuʻi, a me nā inhalers) ʻaʻole pale keiki a hiki i nā keiki ʻōpio ke wehe maʻalahi iā lākou. No ka pale ʻana i nā keiki ʻōpio mai ka lāʻau make, laka mau i nā pāpale palekana a kau koke i ka lāʻau i kahi palekana - kahi i luna a mamao a mai ko lākou alo a hiki. http://www.upandaway.org

Pono e hoʻolei ʻia nā lāʻau i koi ʻole ʻia i nā ala kūikawā e hōʻoia i ka hiki ʻole i nā holoholona, ​​nā keiki, a me nā poʻe ʻē aʻe ke hoʻopau iā lākou. Eia nō naʻe, ʻaʻole pono ʻoe e kaomi i kēia lāʻau i ka lua. Akā, ʻo ke ala ʻoi loa e hoʻolilo i kāu lāʻau i loko o kahi papahana hoʻihoʻi lāʻau. E kamaʻilio me kāu kauka lāʻau a kāhea paha i kāu ʻōpala a me nā hana hoʻopōʻaiapuni kūloko e aʻo e pili ana i nā papahana hoʻihoʻi i kou kaiāulu. E ʻike i ka pūnaewele palekana o kā FDA's Disposal of Medicines (http://goo.gl/c4Rm4p) no ka ʻike hou aku inā ʻaʻohe ou komo i kahi papahana hoʻihoʻi.

I ke kumu o ka overdose, e kāhea i ka helpline kaohi lāʻau make ma 1-800-222-1222. Loaʻa ka ʻike ma ka pūnaewele ma https://www.poisonhelp.org/help. Inā ua hina ka mea i hoʻomāinoino ʻia, loaʻa ka hopu ʻana, pilikia i ka hanu ʻana, a i ʻole hiki ʻole ke ala aʻe, e kāhea koke i nā lawelawe kūikawā ma 911.

Hiki i nā ʻōuli o ka overdose ke hoʻopili i kēia mau mea:

• fiva, ʻeha ka ʻāʻī, haʻalulu, a me nā ʻōuli ʻē aʻe o ka maʻi
• wikiwiki, kūlike ʻole, a kuʻi paha i ka puʻuwai puʻuwai
• luhi
• ʻeha ka umauma

Mai ʻae i kahi mea ʻē aʻe e lawe i kāu lāʻau. E nīnau i kāu kauka lāʻau i nā nīnau āu e pili ana i ka hoʻopiha hou ʻana i kāu kuhikuhi.

He mea nui iā ʻoe e mālama i kahi papa inoa i kākau ʻia a me nā lāʻau lapaʻau ʻole (over-the-counter) lāʻau āu e lawe nei, a me nā huahana e like me nā huaora, nā minelala, a i ʻole nā ​​mea hoʻopiliʻai aʻe. Pono ʻoe e lawe i kēia papa inoa me ʻoe i kēlā me kēia manawa ke kipa ʻoe i ke kauka a i ʻole inā ʻae ʻia ʻoe i kahi haukapila. He ʻike nui nō hoʻi ia e lawe pū me ʻoe inā pilikia ʻo ka pilikia.

• Iclusig^®